Seasonal malaria chemoprevention with sulfadoxine–pyrimethamine plus amodiaquine in children

Seasonal malaria chemoprevention with sulfadoxine–pyrimethamine plus amodiaquine in children PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240073698
Category : Medical
Languages : en
Pages : 62

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Book Description

Seasonal malaria chemoprevention with sulfadoxine–pyrimethamine plus amodiaquine in children

Seasonal malaria chemoprevention with sulfadoxine–pyrimethamine plus amodiaquine in children PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240073698
Category : Medical
Languages : en
Pages : 62

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Book Description


ClinicalTrials

ClinicalTrials PDF Author: Curtis L. Meinert
Publisher: OUP USA
ISBN: 0195387880
Category : Medical
Languages : en
Pages : 702

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Book Description
The classic, definitive guide to the design, conduct, and analysis of randomized clinical trials.

Malaria Immunology

Malaria Immunology PDF Author: Peter Perlmann
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805573766
Category : Medical
Languages : en
Pages : 422

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Book Description
Despite extensive efforts to control it, malaria is still one of the most devastating infectious diseases worldwide. This book, now in its second edition, provides a broad and up-to-date overview of the rapidly expanding field of malaria immunology and its importance in the control of this disease. The first section deals with the malaria parasite and its interactions with both the vertebrate host and the mosquitoes which transmit the disease. In the second part, the mechanisms of immunity and their regulation by environmental and genetic factors are discussed. Finally, this volume contains several chapters on malaria vaccine development, describing the application of the most recent vaccine technologies as well as ongoing and planned vaccine trials. Authored by well-recognized experts, this volume not only demonstrates the rapid progress being made in the search for vaccines against malaria, but also broadens our understanding of immunity to infection in general. It is therefore highly recommended reading for all scientists and professionals in the fields of immunology, infection and vaccine development.

Disease Control Priorities, Third Edition (Volume 8)

Disease Control Priorities, Third Edition (Volume 8) PDF Author: Donald A. P. Bundy
Publisher: World Bank Publications
ISBN: 1464804397
Category : Medical
Languages : en
Pages : 977

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Book Description
More children born today will survive to adulthood than at any time in history. It is now time to emphasize health and development in middle childhood and adolescence--developmental phases that are critical to health in adulthood and the next generation. Child and Adolescent Health and Development explores the benefits that accrue from sustained and targeted interventions across the first two decades of life. The volume outlines the investment case for effective, costed, and scalable interventions for low-resource settings, emphasizing the cross-sectoral role of education. This evidence base can guide policy makers in prioritizing actions to promote survival, health, cognition, and physical growth throughout childhood and adolescence.

Saving Lives, Buying Time

Saving Lives, Buying Time PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309165938
Category : Medical
Languages : en
Pages : 384

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Book Description
For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called "artemisinins" are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.

WHO guideline on mass drug administration of azithromycin to children under five years of age to promote child survival

WHO guideline on mass drug administration of azithromycin to children under five years of age to promote child survival PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240009582
Category : Medical
Languages : en
Pages : 54

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Book Description
The purpose of the guideline was to provide an evidence-informed recommendation on whether mass drug administration of azithromycin, as a public health intervention for the reduction of under-five mortality, should (a) be rolled out universally in low- and middle-income countries, (b) be applied only in some situational contexts in low-and middle-income countries or (c) not be used at all.

Guidelines for the Treatment of Malaria. Third Edition

Guidelines for the Treatment of Malaria. Third Edition PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241549122
Category : Medical
Languages : en
Pages : 317

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Book Description
Malaria remains an important cause of illness and death in children and adults in countries in which it is endemic. Malaria control requires an integrated approach including prevention (primarily vector control) and prompt treatment with effective antimalarial agents. Malaria case management consisting of prompt diagnosis and effective treatment remains a vital component of malaria control and elimination strategies. Since the publication of the first edition of the Guidelines for the treatment of malaria in 2006 and the second edition in 2010 all countries in which P. falciparum malaria is endemic have progressively updated their treatment policy from use of ineffective monotherapy to the currently recommended artemisinin-based combination therapies (ACT). This has contributed substantially to current reductions in global morbidity and mortality from malaria. Unfortunately resistance to artemisinins has arisen recently in P. falciparum in South-East Asia which threatens these gains. This third edition of the WHO Guidelines for the treatment of malaria contains updated recommendations based on a firmer evidence base for most antimalarial drugs and in addition include recommendation on the use of drugs to prevent malaria in groups at high risk. The Guidelines provide a framework for designing specific detailed national treatment protocols taking into account local patterns of resistance to antimalarial drugs and health service capacity. It provides recommendations on treatment of uncomplicated and severe malaria in all age groups all endemic areas in special populations and several complex situations. In addition on the use of antimalarial drugs as preventive therapy in healthy people living in malaria-endemic areas who are high risk in order to reduce morbidity and mortality from malaria. The Guidelines are designed primarily for policy-makers in ministries of health who formulate country-specific treatment guidelines. Other groups that may find them useful include health professionals and public health and policy specialists that are partners in health or malaria control and the pharmaceutical industry. The treatment recommendations in the main document are brief; for those who wish to study the evidence base in more detail a series of annexes is provided with references to the appropriate sections of the main document.

Management of Severe Malaria

Management of Severe Malaria PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241545232
Category : Medical
Languages : en
Pages : 84

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Book Description
Malaria continues to be a major health problem in many parts of the world, with over 2,400 million people in 100 countries at risk of infection. This handbook is an updated edition of 'Management of severe and complicated malaria', providing practical guidance on the diagnosis and management of severe falciparum malaria, a form of the disease that can have life-threatening complications if treatment is delayed.

World Malaria Report 2018

World Malaria Report 2018 PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241565659
Category : Medical
Languages : en
Pages : 210

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Book Description
This year s report shows that after an unprecedented period of success in global malaria control progress has stalled. Data from 2015?2017 highlight that no significant progress in reducing global malaria cases was made in this period. There were an estimated 219 million cases and 435 000 related deaths in 2017. The World malaria report 2018 draws on data from 90 countries and areas with ongoing malaria transmission. The information is supplemented by data from national household surveys and databases held by other organizations.

World Malaria Report 2015

World Malaria Report 2015 PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241565152
Category : Medical
Languages : en
Pages : 283

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Book Description
The World Malaria Report 2015assesses global malaria disease trends and changes in the coverage and financing of malaria control programs between 2000 and 2015. It also summarizes progress towards international targets, and provides regional and country profiles that summarize trends in each WHO region and each country with malaria. The report is produced with the help of WHO regional and country offices, ministries of health in endemic countries, and a broad range of other partners. The data presented are assembled from the 96 countries and territories with ongoing malaria transmission, and a further five countries that have recently eliminated malaria. Most data are those reported for 2014 and 2015, although in some cases projections have been made into 2015, to assess progress towards targets for 2015.