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Author: John Stephenson
Publisher: Elsevier
ISBN: 0323146686
Category : Science
Languages : en
Pages : 540
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Book Description
Molecular Biology of RNA Tumor Viruses deals with the molecular biology and biologic significance of RNA tumor viruses. Methods and procedures with broad application to diverse areas of molecular biology, including cell culture procedures, competition radioimmunoassays, molecular hybridization, oligonucleotide mapping, heteroduplex mapping, and restriction endonuclease techniques, are considered. This book is organized into 12 chapters and begins with a historical overview of tumor virology beginning with the early studies of Peyton Rous and leading up to the significant surge of activity during the later decade. The biology of endogenous retroviruses, their transmission both within and between species, and cellular regulatory factors influencing their expression are subsequently discussed. This book then addresses the nature and origin of transforming RNA viruses and gives a detailed review of knowledge concerning the genomic structure of type C viruses. Translational products encoded by the type C viral genome are examined in ensuing chapters, emphasizing the viral reverse transcriptase. Other mammalian retroviruses, including the mouse mammary tumor virus and type D isolates of primates, are also described. The book concludes by evaluating the possibility of direct etiologic involvement of either endogenous or exogenous RNA tumor viruses in human cancers. This book will be of value both to graduate students and to established investigators with specific interest in other aspects of molecular biology.
Author: John Stephenson
Publisher: Elsevier
ISBN: 0323146686
Category : Science
Languages : en
Pages : 540
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Book Description
Molecular Biology of RNA Tumor Viruses deals with the molecular biology and biologic significance of RNA tumor viruses. Methods and procedures with broad application to diverse areas of molecular biology, including cell culture procedures, competition radioimmunoassays, molecular hybridization, oligonucleotide mapping, heteroduplex mapping, and restriction endonuclease techniques, are considered. This book is organized into 12 chapters and begins with a historical overview of tumor virology beginning with the early studies of Peyton Rous and leading up to the significant surge of activity during the later decade. The biology of endogenous retroviruses, their transmission both within and between species, and cellular regulatory factors influencing their expression are subsequently discussed. This book then addresses the nature and origin of transforming RNA viruses and gives a detailed review of knowledge concerning the genomic structure of type C viruses. Translational products encoded by the type C viral genome are examined in ensuing chapters, emphasizing the viral reverse transcriptase. Other mammalian retroviruses, including the mouse mammary tumor virus and type D isolates of primates, are also described. The book concludes by evaluating the possibility of direct etiologic involvement of either endogenous or exogenous RNA tumor viruses in human cancers. This book will be of value both to graduate students and to established investigators with specific interest in other aspects of molecular biology.
Author:
Publisher:
ISBN:
Category : Oncogenic viruses
Languages : en
Pages : 1254
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Book Description
Author: Blossom Damania
Publisher: Springer Science & Business Media
ISBN: 0387689451
Category : Medical
Languages : en
Pages : 805
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Book Description
This unique book focuses on the DNA viruses in the human population that are associated with cancers. It covers most of the viruses that are thought to contribute to human malignancy. This book represents a comprehensive review of the field of DNA tumor virology. Right now, while there are books out there that cover individual viruses that are also covered in this book, there is no single book that covers this topic comprehensively. This book is the first current, comprehensive review of its kind in the market.
Author: Philip Furmanski
Publisher: Springer Science & Business Media
ISBN: 1461325838
Category : Medical
Languages : en
Pages : 430
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Book Description
We stand today on the threshold of a new understanding of cancer. Primarily through the powerful tools of molecular biology, unified hypotheses explaining the origins of the disease are emerging and rapidly being validated. This volume, which presents the latest findings from laboratories throughout the world on the role of RNA tumor viruses in cancer, is a celebration of these achievements and a prediction of further progress leading ultimately to the control of the disease. It is important in this context to recall the natural history or life cycle of RNA cancer virology. From the earliest days of the science, when viruses were first recognized as distinct biologic agents of etiologic significance, their role in cancer was proposed and hotly debated. The critical early discoveries, even those made as recently as 25 years ago, were met with rejection; not skepticism or cautious restraint, but outright rejection. During the 60's, there was a gradual acceptance of the association between viruses and cancer, the result of landmark studies in experimental systems, and this led to a frenzy of activity in the field. There followed another period of doubt and uncertainty, due to the difficulty in attempting to apply directly, and in retrospect inappropriately, the tenets of infectious disease to human cancers, only to have the field resurrected, revitalized and redirected by the explosion of progress in molecular biology and genetics.
Author: Robert C. Bast, Jr.
Publisher: John Wiley & Sons
ISBN: 111900084X
Category : Medical
Languages : en
Pages : 2008
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Book Description
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Author: John Tooze
Publisher:
ISBN:
Category : DNA viruses
Languages : en
Pages : 1418
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Book Description
Author: Rolf Knippers
Publisher: Springer Science & Business Media
ISBN: 3642745784
Category : Medical
Languages : en
Pages : 271
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Book Description
It is surprising, and even disappointing, that there have been very few meetings and published volumes resulting from these meetings that focus attention upon all of the groups of DNA tumor viruses. Historically, separate meetings were held each year for the adenovirus-SV40-polyoma researchers, the herpes viruses, hepatitis B virus and the papillomaviruses. It was as if these four virus groups were four fields of study developing independently with a literature and culture of their own. When a virologist crossed the field from the adenovirus group to the herpesvirus or papillomaviruses, he or she was lost to their former group because of the structure of separate meetings and remote literature. This, of course, has resulted from historical accident and is being rectified by the rapid progress made in our understanding of how these viruses contribute to the causation of cancer in animals and humans. It was pre cisely because of these factors that it was time to hold a meeting and publish its proceedings on the subject of transforming proteins of DNA tumor viruses. For the first time, DNA tumor viruses were defined as all of the virus groups that can contribute to cancer in animals with the exception, unfortunately, of the . poxviruses. The purpose of the meeting was to bring together scientists who rarely attend meetings together but actually work on the same problems with different viruses.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 188
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Book Description
Author: Howard M. Temin
Publisher:
ISBN:
Category : Oncogenic viruses
Languages : en
Pages : 328
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Book Description
Author: Piet Emmelot
Publisher:
ISBN:
Category : CEA (Oncology)
Languages : en
Pages : 404
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Book Description
