Author: United States. National Commission for the Review of Antitrust Laws and Procedures
Publisher:
ISBN:
Category : Antitrust law
Languages : en
Pages : 336
Book Description
Reports of case studies project and advisory panels
Author: United States. National Commission for the Review of Antitrust Laws and Procedures
Publisher:
ISBN:
Category : Antitrust law
Languages : en
Pages : 336
Book Description
Publisher:
ISBN:
Category : Antitrust law
Languages : en
Pages : 336
Book Description
The Prevention and Treatment of Missing Data in Clinical Trials
Author: National Research Council
Publisher: National Academies Press
ISBN: 030918651X
Category : Medical
Languages : en
Pages : 163
Book Description
Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.
Publisher: National Academies Press
ISBN: 030918651X
Category : Medical
Languages : en
Pages : 163
Book Description
Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.
The Final Report of the Joint Commission on Prescription Drug Use, Inc. ; Prepared for the Subcommittee on Health and Scientific Research of the Committee on Labor and Human Resources, United States Senate
Author: Joint Commission on Prescription Drug Use
Publisher:
ISBN:
Category : Drug utilization
Languages : en
Pages : 180
Book Description
Publisher:
ISBN:
Category : Drug utilization
Languages : en
Pages : 180
Book Description
Defense Manpower Commission Staff Studies and Supporting Papers
Author: United States. Defense Manpower Commission
Publisher:
ISBN:
Category : Recruiting and enlistment
Languages : en
Pages : 1318
Book Description
Publisher:
ISBN:
Category : Recruiting and enlistment
Languages : en
Pages : 1318
Book Description
Reports of Studies Commissioned by the Panel
Author: Canada. Comité d'examen public des systèmes de sécurité des navires-citernes et de la capacité d'intervention en cas de déversements en milieu marin
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Our Common Future
Author:
Publisher:
ISBN: 9780195531916
Category : Australia
Languages : en
Pages : 400
Book Description
Publisher:
ISBN: 9780195531916
Category : Australia
Languages : en
Pages : 400
Book Description
Progressive Failure Studies of Stiffened Panels Subjected to Shear Loading
Author: Damodar R. Ambur
Publisher: DIANE Publishing
ISBN: 1428995536
Category :
Languages : en
Pages : 25
Book Description
Publisher: DIANE Publishing
ISBN: 1428995536
Category :
Languages : en
Pages : 25
Book Description
Arctic Research of the United States
Author:
Publisher:
ISBN:
Category : Arctic regions
Languages : en
Pages : 900
Book Description
Publisher:
ISBN:
Category : Arctic regions
Languages : en
Pages : 900
Book Description
Making Health Care Decisions: Report
Author: United States. President's Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research
Publisher:
ISBN:
Category : Decision making
Languages : en
Pages : 212
Book Description
Publisher:
ISBN:
Category : Decision making
Languages : en
Pages : 212
Book Description
Case Studies in US Trade Negotiation Volume 2
Author: Charan Devereaux
Publisher: Columbia University Press
ISBN: 088132471X
Category : Political Science
Languages : en
Pages : 391
Book Description
Between 1992 and 2000, US exports rose by 55 percent. By the year 2000, trade summed to 26 percent of US GDP, and the United States imported almost two-thirds of its oil and was the world's largest host country for foreign investors. America's interest in a more open and prosperous foreign market is now squarely economic. These case studies in multilateral trade policymaking and dispute settlement explore the changing substance of trade agreements and also delve into the negotiation process—the who, how, and why of decision making. These books present a coherent description of the facts that will allow for discussion and independent conclusions about policies, politics, and processes. Volume 2 presents five cases on trade negotiations that have had important effects on trade policy rulemaking, as well as an analytic framework for evaluating these negotiations.
Publisher: Columbia University Press
ISBN: 088132471X
Category : Political Science
Languages : en
Pages : 391
Book Description
Between 1992 and 2000, US exports rose by 55 percent. By the year 2000, trade summed to 26 percent of US GDP, and the United States imported almost two-thirds of its oil and was the world's largest host country for foreign investors. America's interest in a more open and prosperous foreign market is now squarely economic. These case studies in multilateral trade policymaking and dispute settlement explore the changing substance of trade agreements and also delve into the negotiation process—the who, how, and why of decision making. These books present a coherent description of the facts that will allow for discussion and independent conclusions about policies, politics, and processes. Volume 2 presents five cases on trade negotiations that have had important effects on trade policy rulemaking, as well as an analytic framework for evaluating these negotiations.