Recent Frontiers of Phytochemicals

Recent Frontiers of Phytochemicals PDF Author: Siddhartha Pati
Publisher: Elsevier
ISBN: 0443158088
Category : Science
Languages : en
Pages : 706

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Book Description
Phytochemicals have been present in human diet and life since the birth of mankind, including the consuming of plant foods and the application of herbal treatments. This coevolutionary interaction of plants and people has resulted in humans' reliance on food and medicinal plants as sources of macronutrients, micronutrients, and bioactive phytochemicals. Phytochemicals can be used as adjuvant agents and sensitizers in traditional antibiotic and anticancer therapy, reducing the potential of selecting resistant microbial strains and cancer cells. Recent Frontiers of Phytochemicals addresses the many processes of potential phytochemical evaluation of known sources, with a focus on phytochemical and pharmacological evaluations, and computational research into the structures and pharmacological mechanisms of natural products and their applications in medicine, food and biotech. - Novel extraction, characterization, and application method for phytochemicals in food, pharmacology, and biotechnology - Colour illustrations and extensive tables with state-of-art information - Covers potential sources of phytochemicals, their extraction and characterization techniques

Recent Frontiers of Phytochemicals

Recent Frontiers of Phytochemicals PDF Author: Siddhartha Pati
Publisher: Elsevier
ISBN: 0443158088
Category : Science
Languages : en
Pages : 706

Get Book Here

Book Description
Phytochemicals have been present in human diet and life since the birth of mankind, including the consuming of plant foods and the application of herbal treatments. This coevolutionary interaction of plants and people has resulted in humans' reliance on food and medicinal plants as sources of macronutrients, micronutrients, and bioactive phytochemicals. Phytochemicals can be used as adjuvant agents and sensitizers in traditional antibiotic and anticancer therapy, reducing the potential of selecting resistant microbial strains and cancer cells. Recent Frontiers of Phytochemicals addresses the many processes of potential phytochemical evaluation of known sources, with a focus on phytochemical and pharmacological evaluations, and computational research into the structures and pharmacological mechanisms of natural products and their applications in medicine, food and biotech. - Novel extraction, characterization, and application method for phytochemicals in food, pharmacology, and biotechnology - Colour illustrations and extensive tables with state-of-art information - Covers potential sources of phytochemicals, their extraction and characterization techniques

Phytochemicals as Lead Compounds for New Drug Discovery

Phytochemicals as Lead Compounds for New Drug Discovery PDF Author: Chukwuebuka Egbuna
Publisher: Elsevier
ISBN: 0128178914
Category : Science
Languages : en
Pages : 382

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Book Description
Phytochemicals as Lead Compounds for New Drug Discovery presents complete coverage of the recent advances in the discovery of phytochemicals from medicinal plants as models to the development of new drugs and chemical entities. Functional bioactive compounds of plant origin have been an invaluable source for many human therapeutic drugs and have played a major role in the treatment of diseases around the world. These compounds possess enormous structural and chemical diversity and have led to many important discoveries. This book presents fundament concepts and factors affecting the choice for plant-based products, as well as recent advances in computer-aided drug discovery and FDA drug candidacy acceptance criteria. It also details the various bioactive lead compounds and molecular targets for a range of life-threatening diseases including cancer, diabetes, and neurodegenerative diseases. Written by a global team of experts, Phytochemicals as Lead Compounds for New Drug Discovery is an ideal resource for drug developers, phytochemists, plant biochemists, food and medicinal chemists, nutritionists and toxicologists, chemical ecologists, taxonomists, analytical chemists, and other researchers in those fields. It will also be very valuable to professors, students, and researchers in this domain. - Presents fundamental concepts and factors affecting choice for plant-based products - Details the FDA drug candidacy acceptance criteria, including bottlenecks and way forward - Highlights recent advances in computational-based drug discovery - Focuses on the discovery of new drugs and potential druggable targets for the treatment of chronic diseases of world importance

Bioactive Phytochemicals: Perspectives for Modern Medicine

Bioactive Phytochemicals: Perspectives for Modern Medicine PDF Author: V. K. Gupta
Publisher: Daya Publishing House
ISBN: 9789351307068
Category : Medical
Languages : en
Pages : 594

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Book Description
The present volume of the series, "Bioactive Phytochemicals: Perspectives for Modern Medicine - Vol. 3" with 21 original research and review articles written by eminent scientists and researchers from within India and abroad has been compiled, and the notable amongst which include: Lupeol as Anticancer Drug; Bioactive Phytochemicals as Phytomedicine and its Pharmacology and Toxicology of Genus Capparis; Artesunate with its Antimalarial Profile; Fractionation and Structural Characterization of Antimicrobials from Woodfordia fruticosa Kurz.; Exocyclic-Nitrogen Alkaloids in Herbalism as a Source of New Drugs; Naringin, a Citrus Flavonone Inhibits the Benzo[a]pyrene (BaP)-Induced Forestomach Carcinogenesis in Mice; Capsaicin Prevents Oxidative Stress During D-galactosamine Induced Experimental Hepatitis; A Review on Rhizophora Genus: Therapeutically Important Perspective Phytochemical Constituents; Rotenoids as Anticancer Agents; Plant Lignans: Potent Anticancer Agents; Potentials of Dietary Polyphenols to Modulate Wnt/b-Catenin Signaling Pathway; Exploitation of Algae as Priceless Source of Potential Commercial High-Value Compounds; Hypericum spp.: A Resource from Wild Mediterranean Flora for the Treatment of Mild Depression; Herbs and Herbal Products against some Psychiatric Disorders; The Current Status of Bioactive Metabolites From the Genus Juniperus; Bioactive Phytochemicals - An Overview; New Phyto-Enzymes of Therapeutic and Industrial Values; Efficiency of Garlic Derived Phytochemicals against Advanced Metabolic Disorders; Potential of Pulse Derived Phytochemicals against Advanced Physiological Threats; Potential Bioactive Phytoconstituents and Synthesis of Modern Antimalarials; and Traditional Medicinal Plants for Anticancer Activity. The book like previous volumes shall prove very valuable and an important research compendium that shall stimulate interest of scientific community particularly phytochemists, biochemists, pharmacologists, ethnopharmacologists, ethnobotanists and others engaged in the allied disciplines.

Handbook of Dietary Phytochemicals

Handbook of Dietary Phytochemicals PDF Author: Jianbo Xiao
Publisher: Springer
ISBN: 9789811541476
Category : Technology & Engineering
Languages : en
Pages : 1953

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Book Description
This book summarizes recent advances in the chemistry, bioactivity, nutrition, and functional aspects of dietary phytochemicals, as well as the health and functional aspects of foods rich in phytochemicals. Consisting of forty-four chapters, it discusses the different chemical types of phytochemicals in our diets and food and presents data collected from animal or human experiments that are directly related to human health. Each chapter covers the chemistry, epidemiological study, bioavailability, bioactivity (animal experiments) function in humans and safety, as well as products on the market. Moreover, the more than 200 figures make it easy to grasp the main findings in each area.

BIOACTIV PHYTOCHEMCLS PERSP MOD MED

BIOACTIV PHYTOCHEMCLS PERSP MOD MED PDF Author: Vijay Kumar Gupta
Publisher:
ISBN: 9789351300922
Category : Botanical chemistry
Languages : en
Pages :

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Book Description


Bioactive Phytochemicals

Bioactive Phytochemicals PDF Author: Javed Ahamad
Publisher:
ISBN: 9789811464478
Category :
Languages : en
Pages : 238

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Book Description
Natural bioactive compounds from medicinal plants are inexplicably diverse in chemical structure and biological properties. The unmet therapeutic requirements for various diseases serve as a guide for researchers to study natural compounds. These studies are intended to isolate, identify the structural characterization and eventually discover the pharmacological activity of natural compounds from their plant sources with the goal of treating specific diseases. Bioactive Phytochemicals: Drug Discovery to Product Development explores the scope and approaches of drug discovery from natural products. Chapters in the book cover information about the cultivation, collection and processing of medicinal plants, the methods and high throughput techniques for isolation and characterization of bioactive phytochemicals and pharmacological screening for activity, formulation and quality control. Information about the regulations specified for natural medicinal products in different region of the world is also presented, followed by a concluding chapter devoted to the role of natural herbal products for treatment of human diseases such as cancer, cardiovascular diseases, diabetes, obesity, inflammation and neurological disorders. Each chapter concludes with a general reference section, which is a bibliographic guide to more advanced texts. The contributing authors for this volume are drawn from a rich blend of experts in various areas of herbal medicine which encompass herbal drug discovery to product development. The concise and organized layout along with a broad coverage of phytochemistry and drug discovery makes this book a suitable reference for students of medicinal chemistry, researchers and industry professionals interested in herbal product development.

Poisonous Plants and Phytochemicals in Drug Discovery

Poisonous Plants and Phytochemicals in Drug Discovery PDF Author: Andrew G. Mtewa
Publisher: John Wiley & Sons
ISBN: 1119650232
Category : Science
Languages : en
Pages : 444

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Book Description
Focusing on phytochemicals and their potential for drug discovery, this book offers a comprehensive resource on poisonous plants and their applications in chemistry and in pharmacology. Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discovery Covers the mechanisms, benefits, risks and management protocols of phytotoxins in a scientific laboratory and the usefulness in drug discovery Presents chapters in a carefully designed, clear order, making it an ideal resource for the academic researcher or the industry professional at any stage in their career

Phytochemicals

Phytochemicals PDF Author: Toshiki Asao
Publisher: BoD – Books on Demand
ISBN: 1789843774
Category : Science
Languages : en
Pages : 220

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Book Description
Phytochemicals provides original research work and reviews on the sources of phytochemicals, and their roles in disease prevention, supplementation, and accumulation in fruits and vegetables. The roles of anthocyanin, flavonoids, carotenoids, and taxol are presented in separate chapters. Antioxidative and free radicle scavenging activity of phytochemicals is also discussed. The medicinal properties of Opuntia, soybean, sea buckthorn, and gooseberry are presented in a number of chapters. Supplementation of plant extract with phytochemical properties in broiler meals is discussed in one chapter. The final two chapters include the impact of agricultural practices and novel processing technologies on the accumulation of phytochemicals in fruits and vegetables. This book mainly focuses on medicinal plants and the disease-preventing properties of phytochemicals, which will be a useful resource to the reader.

Phytochemical Nanodelivery Systems as Potential Biopharmaceuticals

Phytochemical Nanodelivery Systems as Potential Biopharmaceuticals PDF Author: J. Basilio Heredia
Publisher: Elsevier
ISBN: 0323903908
Category : Technology & Engineering
Languages : en
Pages : 366

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Book Description
Phytochemical Nanodelivery Systems as Potential Biopharmaceuticals comprehensively reviews current information on nanotechnology applied to phytochemical nanoencapsulation to enhance their bioavailability and bioactivity. The book is divided into two sections, the first section critically reviews current information on the field of nanotechnology and phytochemicals, and the second section highlights the pre-clinical and clinical studies of phytochemicals to comprehensively review the efficacy of these molecules as drugs of human use. Phytochemical Nanodelivery Systems as Potential Biopharmaceuticals provides a useful overview of this rapidly evolving field for materials scientists and pharmaceutical scientists, as well as for those with an interest in biopharmaceuticals from plant sources, such as organic chemists and food scientists. Provides an introduction to both phytochemicals and nanomaterials for use in biopharmaceutics, allowing both materials scientists and pharmaceutical scientists to gain a basic understanding of each field Reviews key phytochemical types for use as biopharmaceuticals, including terpenes, alkaloids, glucosinolates and more Explores the various nanomaterials and nanoencapsulation techniques for administration of phytochemical nanoformulations

Phytochemicals Targeting Tumor Microenvironment in Gastrointestinal Cancers

Phytochemicals Targeting Tumor Microenvironment in Gastrointestinal Cancers PDF Author: Ganji Purnachandra Nagaraju
Publisher: Springer Nature
ISBN: 303048405X
Category : Medical
Languages : en
Pages : 341

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Book Description
Gastrointestinal (GI) malignancies account for a large portion of cancers worldwide. Although incidence of esophageal, gastric, and colorectal cancers has decreased in recent years, pancreatic and liver cancer have increased. The mainstay of GI cancer therapy is chemoradiation and surgery. Despite significant medical advancements, diagnosis and therapy for GI cancers remain challenging due to tumor cell resistance to chemoradiotherapy. The tumor’s increased cell signalling due to excessive transcription factor activation and increased stellate cell activity leads to collagen deposition formation of a dense stroma around the tumor, which prevents drugs from reaching the malignant cells. This leads to tumor chemoresistance. To circumvent these difficulties, drug therapy targeting the tumor’s specific microenvironment and the additive anticancer effect of phytochemicals can allow for more effective treatment. This volume will be the first on the market on the topic of phytochemicals and their effect on the tumor microenvironment (TME). TME is an emerging area of research and the book will be a welcome introductory addition to the field.