Author: K. Nagata
Publisher: Springer Science & Business Media
ISBN: 4431669701
Category : Science
Languages : en
Pages : 261
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Book Description
The metabolism of all living organisms consists of elaborate and complex interactions among numbers of biomolecules, including protein-protein interactions. BIACORE is a new device that uses surface plasmon resonance for kinetic analysis of molecular interactions and automates whole analytical processes. The number of users of BIACORE is increasing worldwide, but until now nothing had been published in English to explain the principles of this new methodology and the kinds of applications it makes available. This updated and revised version of the Japanese original explains the underlying principles of BIACORE, providing concrete examples that utilize the methodology for analysis in areas ranging from basic to applied sciences. With its generous use of illustrations, this book is a valuable source of information for all users of BIACORE.
Author: Kazuhiro Nagata
Publisher: Springer Verlag Tokyo
ISBN:
Category : Biomolecules
Languages : en
Pages : 276
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Book Description
Author: Ang Yan Shan
Publisher: Springer
ISBN: 9811321884
Category : Technology & Engineering
Languages : en
Pages : 224
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Book Description
This book provides essential insights into designing a localized DNA circuit to promote the rate of desired hybridization reactions over undesired leak reactions in the bulk solution. The area of dynamic DNA nanotechnology, or DNA circuits, holds great promise as a highly programmable toolbox that can be used in various applications, including molecular computing and biomolecular detection. However, a key bottleneck is the recurring issue of circuit leakage. The assembly of the localized circuit is dynamically driven by the recognition of biomolecules – a different approach from most methods, which are based on a static DNA origami assembly. The design guidelines for individual reaction modules presented here, which focus on minimizing circuit leakage, are established through NUPACK simulation and tested experimentally – which will be useful for researchers interested in adapting the concepts for other contexts. In the closing section, the design concepts are successfully applied to the biomolecular sensing of a broad range of targets including the single nucleotide mutations, proteins, and cell surface receptors.
Author: Sanjeeva Srivastava
Publisher: CRC Press
ISBN: 1000648672
Category : Medical
Languages : en
Pages : 272
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Book Description
Proteomics aims to study all the proteins of human and other living systems, as well as their properties to provide an integrated view of cellular processes. The study of proteomics involves the application of rapidly evolving high-throughput technologies and new platforms that are coming forward regularly, providing versatile novel tools for biomedical and pharmaceutical applications. This book provides a detailed understanding of the basics of proteins and proteomics, gel based-proteomics techniques, basics of mass spectrometry and quantitative proteomics, interactomics: basics and applications, and advancements in proteomics. It also covers basic knowledge about sample preparation, mass spectrometry workflow, different chromatography technologies and quantitative proteomics. The text highlights the application and challenges of various high-throughput integrated proteomics technologies capable of fast and accurate screening of thousands of biomolecules, which are found to be very effective for studying disease pathobiology and identification of next-generation biomarkers and potential drug/vaccine targets; and are therefore considered valuable tools for multidisciplinary research. Features Basics of proteins and proteomics techniques In-depth understanding of mass spectrometry and quantitative proteomics An overview of interactomics and its application for translational research Advancement in the field of proteomics and challenges in clinical applications We hope the knowledge gained from reading this book will intrigue and motivate young minds to explore future opportunities in the constantly evolving field of proteomics.
Author: W.R. Heineman
Publisher: Elsevier
ISBN: 1483297179
Category : Science
Languages : en
Pages : 573
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Book Description
Keeping up to date with new biosensors developments has been getting harder ... – one of the fastest moving fields of academic and industrial research in the world – a constant stream of new commercial applications – centres of research excellence all over Europe, North America and the Pacific Rim – enormous implications for monitoring personal health and fitness, the food we eat, the environment, health services and industry The answer came on 20–22 May 1992, with BIOSENSORS 92. With a core of invited speakers and over 220 original contributed papers from 24 countries, BIOSENSORS 92 was the largest and most comprehensive event of its kind – a response to the growing importance of biosensors as a powerful new technology. Elsevier Advanced Technology, the organizers of BIOSENSORS 92, have now published the proceedings of this important event. Biosensors 92 Proceedings contains over 150 papers presenting current research and developments straight from those who are leading the way in: – Enzyme–based Sensors – Affinity Sensors – Environmental Monitoring using Biosensors – Biosensors and Bioelectronics Biosensors 92 Proceedings – Your key to current awareness in sensor technology for just £90 [dollar rate subject to current £/$ exchange rate].
Author: Leo M. L. Nollet
Publisher: John Wiley & Sons
ISBN: 081380874X
Category : Business & Economics
Languages : en
Pages : 909
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Book Description
Simpson (food science and agricultural chemistry, McGill U., Canada) brings together academics and industry professionals working in food biochemistry, processing, and safety around the world for this 45-chapter textbook aimed at food scientists, researchers and technologists in the food industry, and faculty and students in food science, technology, and engineering. It combines the areas of food biochemistry and food processing to help them rationalize and develop more effective strategies to produce and preserve food. It covers the essential principles of food biochemistry, enzymology, and food processing, then the biochemistry of meat, poultry, seafoods, milk, fruits, vegetables, cereals, and fermented foods, and food microbiology and safety. Along with updates to several chapters, this edition has been revised to incorporate safety considerations and the chemical changes induced by processing in the biomolecules of food in each chapter. It includes a new section on health and functional foods and 10 new chapters on topics like thermally and minimally processed foods, separation technology, and allergens.
Author: Edwin Silverman
Publisher: CRC Press
ISBN: 1444114662
Category : Medical
Languages : en
Pages : 554
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Book Description
There has been a recent explosion of knowledge in the field of respiratory genetics. This authoritative text brings together current knowledge in respiratory genetics in a single volume. The book includes a comprehensive introductory section to provide guidance and aid understanding of key basic concepts in respiratory genetics, including statistic
Author: Gerhard Isenberg
Publisher: Springer Science & Business Media
ISBN: 3642803709
Category : Science
Languages : en
Pages : 253
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Book Description
In spite of tremendous scientific progress over the past years, cell biologists do not yet understand the fundamental processes that determine the life cy cle of a cell. Such are: cell movement and cell spreading, cell division, cell communication, cell signaling, cell regeneration and cell death. Biochemistry has enabled us to recognize and to isolate an overwhelming number of new proteins. In vitro assays and the reinjection of proteins into cells and tissues have provided insights into molecular functions and cellular mechanisms. The renaissance of the genetic approach by applying restriction enzymes and vectors, PCR and antisense technology has enabled us to overexpress certain cellular products, to make altered constructs of cell components or to create "knock-out" mutants that entirely lack the factor of interest. Amazingly en ough, all these molecular toys have led to a stream of information but not, in a comparable degree, to a better understanding. Has the puzzle become too complex to get solved; or are the windows too small that we are looking through? As an attempt to answer both questions, the aim of the present mono graph Modern Optics, Electronics and High Precision Techniques in Cell Biol ogy is first to provide cell and molecular biologists with a whole new scope of easily applicable techniques including brand-new optical, biophysical, physicochemical and biosensoric devices. Secondly, these newly developed techniques allow us to look at cells and biological systems as a whole.
Author:
Publisher: Elsevier
ISBN: 0323853102
Category : Science
Languages : en
Pages : 426
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Book Description
Surface Plasmon Resonance in Bioanalysis, Volume 95 in the Comprehensive Analytical Chemistry series, contains a wide range of topics on the applications and new advances of surface plasmon resonance (SPR) in bioanalysis, including Surface plasmon resonance microscopy for single-cell based drug screening, Phase-Sensitive Surface Plasmon Resonance Sensors for Highly Sensitive Bioanalysis, SPR coupled to ambient mass spectrometry, Surface Plasmon Resonance Microscopy for activity detection and imaging of single cells, SPR for water pollutant detection and biofouling control, SPR imaging for cellular analysis and detection, Progress in detection of surface palsmon resonance for biorefinery technology, and more. Additional chapters cover Long-range surface plasmon resonance and its biological sensing applications and Critical issues in clinical and biomedical applications of Surface Plasmon Resonance sensing. - Provides updates on the latest applications of SPR microscopy in cell analysis - Covers the latest design in SPR sensing for highly sensitive bioanalysis - Presents the critical issues in clinical and biomedical applications of SPR
Author: Atta-ur- Rahman
Publisher: Bentham Science Publishers
ISBN: 1608051994
Category : Medical
Languages : en
Pages : 371
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Book Description
"Frontiers in Drug Design and Discovery" is an Ebook series devoted to publishing the latest and the most important advances in drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery inclu
