Proceedings of the 2nd Annual Conference on Atmospheric Contamination in Confined Spaces, 4 and 5 May 1966 PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Proceedings of the 2nd Annual Conference on Atmospheric Contamination in Confined Spaces, 4 and 5 May 1966 PDF full book. Access full book title Proceedings of the 2nd Annual Conference on Atmospheric Contamination in Confined Spaces, 4 and 5 May 1966 by . Download full books in PDF and EPUB format.
Author:
Publisher:
ISBN:
Category : Closed respiratory systems (Space environment)
Languages : en
Pages : 340
Get Book
Book Description
Author:
Publisher:
ISBN:
Category : Closed respiratory systems (Space environment)
Languages : en
Pages : 340
Get Book
Book Description
Author:
Publisher:
ISBN:
Category : Closed respiratory systems (Space environment)
Languages : en
Pages : 468
Get Book
Book Description
The report is a complete compilation of the papers presented and the Proceedings of the 3rd Annual Conference on Atmospheric Contamination in Confined Spaces, sponsored by the Aerospace Medical Research Laboratories and held in Dayton, Ohio on 9, 10, and 11 May 1967. Major technical areas discussed by the invited speakers, members of the Open Forum and Conference attendees included toxicological evaluation of atmospheres and contaminants, histopathological evidences of toxicity, evaluation of cabin materials, instruments and detection techniques, measurement of behavioral responses, and life support systems. Included as an Appendix, but not presented at the Conference, is a status report on oxygen toxicity prepared by Dr. Harold Kaplan.
Author:
Publisher:
ISBN:
Category : Closed respiratory systems (Space environment)
Languages : en
Pages : 336
Get Book
Book Description
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 168
Get Book
Book Description
Author:
Publisher:
ISBN:
Category : Human engineering
Languages : en
Pages : 686
Get Book
Book Description
Author: J. D. MacEwen
Publisher:
ISBN:
Category : Low pressure (Science)
Languages : en
Pages : 36
Get Book
Book Description
As extensions of previous short-term experiments on the toxicity of oxygen at reduced pressure in animals, long-term continuous exposures of beagle dogs, rhesus monkeys and albino rats and mice were undertaken. The exposures were for 230 days to 100% oxygen at 5 psia. No mortality occurred in the exposed dogs or monkeys. More rats and mice died in the control groups than in the experimental groups, indicating no effects on mortality due to the experimental conditions. The growth rates of control and experimental rats were almost identical, further indicating lack of deleterious effects. Histopathologic examination of tissues was conducted on all four animal species. No differences were observed between exposed animals and their controls in monkeys, rats or mice. Minimal differences consisting of mild bronchitis and mild congestion were seen in the dogs exposed to 100% oxygen at reduced pressure. One exposed dog exhibited severe pulmonary changes associated with acute interstitial bronchial pneumonia. Periodic measurements of blood constituents showed no significant differences attributable to prolonged oxygen exposure at reduced pressure.
Author:
Publisher:
ISBN:
Category : Aeronautics
Languages : en
Pages : 340
Get Book
Book Description
Author:
Publisher:
ISBN:
Category : Aviation medicine
Languages : en
Pages : 480
Get Book
Book Description
Author: Willis H. Riesen
Publisher:
ISBN:
Category : Oxygen
Languages : en
Pages : 84
Get Book
Book Description
The use of pure oxygen atmospheres at reduced pressure in manned spacecraft has stimulated new research interest. Exposure of humans to pure oxygen at total pressures of 5 to 7 psia for up to 30 days has generally produced only subjective and occasional symptomatic distress. Nevertheless, studies with animals have clearly documented toxicity if the exposure to pure oxygen is at higher total pressures. The selection of suitable oxygen atmospheres for manned space flight and the development of protective measures against toxic manifestations will be considerably facilitated by a clearer understanding of the toxic syndrome. Rats, dogs, and monkeys were exposed to pure (98.5%) oxygen at 1 atm and 1/3 atm in a closed, recirculating chamber and in a nonrecirculating chamber. Rats exposed to a pressure of 1 atm showed significant reduction in efficiency of liver mitochondrial oxidative phosphorylation. Weight loss accompanied this change. Insignificant changes were found in liver or lung mitochondrial oxygen consumption; liver or lung NAD, NADH, or NAD/NADH; and arterial blood lactate and pyruvate, and lactate/pyruvate ratio. A composite index of oxygen toxicity was derived from a multivariant data analysis. Exposure of rats to pure oxygen at 1/3 atm showed slight elevation in P/O ratio in 7 days. The ratio returned to normal in 2 weeks and remained so for 8 months. No significant weight changes were observed. Only preliminary experiments with the dogs and monkeys were conducted, therefore no conclusions can as yet be made. There is an indication that monkeys are more resistant to oxygen toxicity at 1 atm than rats.
Author:
Publisher:
ISBN:
Category : Space medicine
Languages : en
Pages : 508
Get Book
Book Description
