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Author: B. V. Rama Sastry
Publisher: CRC Press
ISBN: 9780849378119
Category : Medical
Languages : en
Pages : 216
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Book Description
Placenta plays a very significant role in the development of secretory and regulatory functions for the maintenance of pregnancy and in the nutrition of the embryo. It shares many functions of the heart, lung, liver, endocrines, and other organs. In Placental Pharmacology, fourteen expert authors discuss how placenta and its component parts can be used effectively in drug development research and in the study of transfer mechanisms across membranes. This reference begins by describing the use of modern biophysical methods to study placental function and prospects for their application in pharmacological research. The next three chapters deal with placental hemodynamics, use of placental tissues and cells in pharmacological assays, and placental transfer of drugs used in pregnancy. Three more chapters contain up-to-date information on molecular biological aspects of placenta currently receiving lots of attention - phospholipase A2 isozymes, imprinted genes and embryogenesis, and placental growth factors. The final chapter describes the clinically relevant topics of placental metabolism and toxicity of homocysteine in placenta. Easy to understand, thorough, and complete, Placental Pharmacology is the perfect resource for scientists interested in placenta and its uses in drug development and testing.
Author: B. V. Rama Sastry
Publisher: CRC Press
ISBN: 9780849378119
Category : Medical
Languages : en
Pages : 216
Get Book Here
Book Description
Placenta plays a very significant role in the development of secretory and regulatory functions for the maintenance of pregnancy and in the nutrition of the embryo. It shares many functions of the heart, lung, liver, endocrines, and other organs. In Placental Pharmacology, fourteen expert authors discuss how placenta and its component parts can be used effectively in drug development research and in the study of transfer mechanisms across membranes. This reference begins by describing the use of modern biophysical methods to study placental function and prospects for their application in pharmacological research. The next three chapters deal with placental hemodynamics, use of placental tissues and cells in pharmacological assays, and placental transfer of drugs used in pregnancy. Three more chapters contain up-to-date information on molecular biological aspects of placenta currently receiving lots of attention - phospholipase A2 isozymes, imprinted genes and embryogenesis, and placental growth factors. The final chapter describes the clinically relevant topics of placental metabolism and toxicity of homocysteine in placenta. Easy to understand, thorough, and complete, Placental Pharmacology is the perfect resource for scientists interested in placenta and its uses in drug development and testing.
Author: Donald Mattison
Publisher: Academic Press
ISBN: 0123860075
Category : Medical
Languages : en
Pages : 496
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Book Description
Clinical Pharmacology During Pregnancy is written for clinicians, physicians, midwives, nurses, pharmacists and other medical professionals directly involved in the care of women during pregnancy. This book focuses on the impact of pregnancy on drug disposition and also includes coverage of treatments for diseases of specific body systems, as well as essential content on dosing and efficacy. Written in a clear and practical manner, this reference provides easily accessible information and clinical guidance on how best to treat women with medications during pregnancy.
Author: Colin Pinnock
Publisher: Cambridge University Press
ISBN: 9780521690799
Category : Medical
Languages : en
Pages : 990
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Book Description
The second edition of Fundamentals of Anaesthesia builds upon the success of the first edition, and encapsulates the modern practice of anaesthesia in a single volume. Written and edited by a team of expert contributors, it provides a comprehensive but easily readable account of all of the information required by the FRCA Primary examination candidate and has been expanded to include more detail on all topics and to include new topics now covered in the examination. As with the previous edition, presentation of information is clear and concise, with the use of lists, tables, summary boxes and line illustrations where necessary to highlight important information and aid the understanding of complex topics. Great care has been taken to ensure an unrivalled consistency of style and presentation throughout.
Author: B. V. Rama Sastry
Publisher: CRC Press
ISBN: 9781439805527
Category : Medical
Languages : en
Pages : 312
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Book Description
Placental Toxicology examines placental transfer and toxicology of drugs and environmental agents to placenta, as well as to fetus. For the first time in a single volume, placental and fetal consequences of exposure of pregnant women to drugs, environmental chemicals, and infections, such as HIV, are discussed. Topics include: The art of in
Author: E.M. Johnson
Publisher: Springer Science & Business Media
ISBN: 3642819192
Category : Medical
Languages : en
Pages : 379
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Book Description
The resolution of links between exposure to components of our complex environmental and causation of reproductive effects in the population constitutes an important problem in the field of toxicology. The focus of this volume is developmental toxicology, which represents one aspect of reproductive toxicology dealing with the study of adverse effects on the developing conceptus. Developmental toxicology, which includes teratogenesis as one of its manifesta tions, provides a fertile field for research in several basic and clinical disciplines; this field also receives input from several disoiplines such as developmental and molecu lar biology, pathology, pharmacology and toxicology, pediatrics and neonatology, and epidemiology. More recently we h~ve seen an emergence of interest in other fields such as perinatal physiology and postnatal behavior which have now become incorporated into the mainstream of research in this discipline. The present volume is an effort to provide a sampling of concepts currently under active investigation in several of the above fields. The authors have endeavored to provide up-to-date in formation on the following topics: detection and analysis of potential hazards to the conceptus in the workplace, pharmacokinetic aspects of the maternal/placental! fetal complex and its relationship to human birth defects, and probable mechanisms of teratogenesis as uncovered in certain well-defined situations. Also included are summaries of newer investigations on the emerging field of postnatal functional evaluations, i. e. , adverse effects on adult activities resultant from in utero exposure to toxic substances.
Author:
Publisher: Academic Press
ISBN: 0128144262
Category : Medical
Languages : en
Pages : 754
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Book Description
Biopharmaceutics and Pharmacokinetics Considerations examines the history of biopharmaceutics and pharmacokinetics. The book provides a biopharmaceutics and pharmacokinetics approach to addressing issues in formulation development and ethical considerations in handling animals. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biopharmaceutics and pharmacokinetics within drug discovery and drug development. Each chapter delves into a particular aspect of this fundamental field to cover the principles, methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to study the chemical and physical properties of drugs and the biological effects they produce. - Examines the most recent developments in biopharmaceutics and pharmacokinetics for pharmaceutical sciences - Covers the principles, methodologies and technologies of biopharmaceutics and pharmacokinetics - Focuses on the pharmaceutical sciences, but also encompasses aspects of toxicology, neuroscience, environmental sciences and nanotechnology
Author: Vicki Clark
Publisher: Oxford University Press
ISBN: 0198713339
Category : Medical
Languages : en
Pages : 1017
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Book Description
This textbook provides an up-to-date summary of the scientific basis, assessment for and provision of anaesthesia throughout pregnancy and labour. It is divided into nine sections including physiology, assessment, complications and systemic disease.
Author: Alison Fiander
Publisher: Cambridge University Press
ISBN: 1107667135
Category : Education
Languages : en
Pages : 557
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Book Description
A fully updated and illustrated handbook providing comprehensive coverage of all curriculum areas covered by the MRCOG Part 1 examination.
Author: Sumner J. Yaffe
Publisher: Lippincott Williams & Wilkins
ISBN: 0781795389
Category : Medical
Languages : en
Pages : 1072
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Book Description
"Neonatal and Pediatric Pharmacology offers guidelines for safe, effective, and rational drug therapy in newborns, children and adolescents. The book provides relevant and useful data on the molecular, physiologic, biochemical, and pharmacologic mechanisms of drug action and therapy in this population. The authors identify areas of innovative basic and translational research necessary for the continuing evaluation and development of drugs for the fetus, newborns, children and adolescents. Neonatal and Pediatric Pharmacology is is a valuable reference for all health care professionals who treat the fetus, newborns, children, and adolescents, including neonatologists, nurses, pediatricians, general practitioners, students, obstetricians, perinatologists, surgeons and allied health professionals. It will be useful anytime during the day and especially in the middle of the night when knowledge of appropriate indications, safe and effective use, dosage, and therapeutic regimen for a certain drug or molecular entity is immediately needed. The book is also directed to those involved in basic, clinical, and other academic pharmacological research, the pharmaceutical industry, and regulatory agencies dealing with drug and therapeutic developments for this population. Those teaching pharmacology and therapeutics will find this compilation of information extremely useful in preparing teaching materials"--Provided by publisher.
Author: Ramesh C Gupta
Publisher: Elsevier
ISBN: 0080481604
Category : Medical
Languages : en
Pages : 1233
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Book Description
Veterinary Toxicology, 2nd edition is a unique single reference that teaches the basic principles of veterinary toxicology and builds upon these principles to offer an essential clinical resource for those practicing in the field. This reference book is thoroughly updated with new chapters and the latest coverage of topics that are essential to research veterinary toxicologists, students, professors, clinicians and environmentalists. Key areas include melamine and cyanuric acid, toxicogenomics, veterinary medical geology, toxic gases, toxicity and safety evaluation of new veterinary pharmaceuticals and much more. The 2nd edition of this popular book represents the collective wisdom of leading contributors worldwide and continues to fill an undeniable need in the literature relating to veterinary toxicology. - New chapters covering important and timely topics such as melamine and cyanuric acid, toxicogenomics, toxic gases and veterinary medical geology - Expanded look at international topics, such as epidemiology of animal poisonings, regulatory guidelines and poisonous plants in Europe - Heavily contributed book with chapters written by qualified and well-experienced authorities across all areas of veterinary toxicology - Problem solving strategies are offered for treatment as well as in-depth knowledge of the basic mechanisms of veterinary toxicology
