Particle Count Method Development for Concentration Standards and Sample Stabilization PDF Download
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Author: Zaid K. Chowdhury
Publisher: American Water Works Association
ISBN: 1583210245
Category : Particle counting (Water treatment plants)
Languages : en
Pages : 196
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Book Description
Author: Zaid K. Chowdhury
Publisher: American Water Works Association
ISBN: 1583210245
Category : Particle counting (Water treatment plants)
Languages : en
Pages : 196
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Book Description
Author:
Publisher: DIANE Publishing
ISBN: 1428900136
Category : Drinking water
Languages : en
Pages : 321
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Book Description
Author: Karl G. Linden
Publisher: IWA Publishing
ISBN: 1843396998
Category : Science
Languages : en
Pages : 124
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Book Description
Disinfection of wastewater is a necessary treatment process for protecting the public from potential exposure to pathogenic microorganisms because many wastewater effluents are discharged into water bodies that may be used for recreation or as future drinking water supplies. Two common forms of disinfection are chlorine and ultraviolet (UV) light. However, microorganisms differ in their susceptibility to UV and chlorine disinfectants. It is necessary to understand how different classes of pathogens respond to UV and chlorine disinfection processes in wastewater to better develop strategies for optimizing the treatment of pathogens in wastewater. It is also recognized that water quality may impact disinfection effectiveness, such as protection of pathogen by particles and disinfectant demand. This study investigated bacteria, viruses and protozoan pathogens. All species of bacteria tested were susceptible to both UV and chlorine, despite differences in antibiotic resistance and tendency to aggregate. Upon exposure to disinfection conditions that could indicate viability of the bacteria tested, but not culturability using common methods, it was found that UV and chlorine were effective in eliminating the capability of viable but non-culturable bacteria to resuscitate and become re-infective. Clostridium spores were resistant to free chlorine and UV disinfection but found to be susceptible to long exposure to monochloramine. Cryptosporidium was resistant to all chlorine forms but very susceptible to UV irradiation. Pathogenic and indicator viruses tested were very susceptible to free chlorine and UV disinfection. UV radiation throughout the 200 to 300 nm range was effective for inactivation of viruses and C. parvum, but wavelengths between 260-270 nm and below 220 nm appeared to be more effective for viruses, suggesting a possible advantage for polychromatic UV sources. Sequential disinfection strategies were proposed and tested to enhance inactivation of various microorganisms. One scenario integrated UV disinfection followed by dynamic chloramination through addition of free chlorine and subsequent transformation to combined chlorine. Further, disinfection of microorganisms in wastewater presents challenges that are inherent to the water matrix, such as pathogens associated with particles. UV and chlorine were both effective for disinfection of coliform in wastewater but chlorine was found to be more effective during long contact times for inactivation of particle associated coliform. In addition to coliform, both Cryptosporidium parvum and Salmonella typhimurium were identified as being particle associated in wastewater using molecular approaches developed to detect microbes in environmental samples
Author: Lawrence K. Wang
Publisher: Springer Science & Business Media
ISBN: 1597452785
Category : Science
Languages : en
Pages : 728
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Book Description
In this essential new volume, Volume 13: Membrane and Desalination Technologies, a panel of expert researchers provide a wealth of information on membrane and desalination technologies. An advanced chemical and environmental engineering textbook as well as a comprehensive reference book, this volume is of high value to advanced graduate and undergraduate students, researchers, scientists, and designers of water and wastewater treatment systems. This is an essential part of the Handbook of Environmental Engineering series, an incredible collection of methodologies that study the effects of pollution and waste in their three basic forms: gas, solid, and liquid. Chapters adopt the series format, employing methods of practical design and calculation illustrated by numerical examples, including pertinent cost data whenever possible, and exploring in great detail the fundamental principles of the field. Volume 13: Membrane and Desalination Technologies is an essential guide for researchers, highlighting the latest developments in principles of membrane technology, membrane systems planning and design, industrial and municipal waste treatments, desalination requirements, wastewater reclamation, biofiltration, and more.
Author: New England Water Works Association
Publisher:
ISBN:
Category : Water-supply
Languages : en
Pages : 578
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Book Description
Author: Sandeep Nema
Publisher: CRC Press
ISBN: 0429576838
Category : Business & Economics
Languages : en
Pages : 1145
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Book Description
Parenteral Medications is an authoritative, comprehensive reference work on the formulation and manufacturing of parenteral dosage forms, effectively balancing theoretical considerations with practical aspects of their development. Previously published as a three-volume set, all volumes have been combined into one comprehensive publication that addresses the plethora of changes in the science and considerable advances in the technology associated with these products and routes of administration. Key Features: Provides a comprehensive reference work on the formulation and manufacturing of parenteral dosage forms Addresses changes in the science and advances in the technology associated with parenteral medications and routes of administration Includes 13 new chapters and updated chapters throughout Contains the contributors of leading researchers in the field of parenteral medications Uses full color detailed illustrations, enhancing the learning process The fourth edition not only reflects enhanced content in all the chapters but also highlights the rapidly advancing formulation, processing, manufacturing parenteral technology including advanced delivery and cell therapies. The book is divided into seven sectionss: Section 1 - Parenteral Drug Administration and Delivery Devices; Section 2 - Formulation Design and Development; Section 3 - Specialized Drug Delivery Systems; Section 4 - Primary Packaging and Container Closure Integrity; Section 5 - Facility Design and Environmental Control; Section 6 - Sterilization and Pharmaceutical Processing; Section 7 - Quality Testing and Regulatory Requirements
Author: Dana Ferguson
Publisher:
ISBN: 9780787635435
Category : Reference
Languages : en
Pages : 558
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Book Description
Author: Feroz Jameel
Publisher: Springer Nature
ISBN: 3030314154
Category : Medical
Languages : en
Pages : 888
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Book Description
The biotechnology/biopharmaceutical sector has tremendously grown which led to the invention of engineered antibodies such as Antibody Drug Conjugates (ADCs), Bispecific T-cell engager (BITES), Dual Variable Domain (DVD) antibodies, and fusion proteins that are currently being used as therapeutic agents for immunology, oncology and other disease conditions. Regulatory agencies have raised the bar for the development and manufacture of antibody-based products, expecting to see the use of Quality by Design (QbD) elements demonstrating an in-depth understanding of product and process based on sound science. Drug delivery systems have become an increasingly important part of the therapy and most biopharmaceuticals for self-administration are being marketed as combination products. A survey of the market indicates that there is a strong need for a new book that will provide “one stop shopping” for the latest information and knowledge of the scientific and engineering advances made over the last few years in the area of biopharmaceutical product development. The new book entitled Development of Biopharmaceutical Drug Device Products is a reference text for scientists and engineers in the biopharmaceutical industry, academia or regulatory agencies. With insightful chapters from experts in the field, this new book reviews first principles, covers recent technological advancements and provides case studies and regulatory strategies relating to the development and manufacture of antibody-based products. It covers topics such as the importance of early preformulation studies during drug discovery to influence molecular selection for development, formulation strategies for new modalities, and the analytical techniques used to characterize them. It also addresses important considerations for later stage development such as the development of robust formulations and processes, including process engineering and modeling of manufacturing unit operations, the design of analytical comparability studies, and characterization of primary containers (pre-filled syringes and vials).Finally, the latter half of the book reviews key considerations to ensure the development and approval of a patient-centered delivery system design. This involves the evolving regulatory framework with perspectives from both the US and EU industry experts, the role of international standards, design control/risk management, human factors and its importance in the product development and regulatory approval process, as well as review of the risk-based approach to bridging between devices used in clinical trials and the to-be-marketed device. Finally, case studies are provided throughout.The typical readership would have biology and/or engineering degrees and would include researchers, scientific leaders, industry specialists and technology developers working in the biopharmaceutical field.
Author: F.D.K. Liddell
Publisher: CRC Press
ISBN: 9780849366468
Category : Science
Languages : en
Pages : 398
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Book Description
The part of this book covering pathogensis and modes of action begins with a chapter on the physicochemical properties of asbestos fibers and a chapter on the deposition and retention of fibers within the lung and their clearance. Some of the effects of asbestos can be reproduced in animal experiments, and the book includes a full review of the results from animal studies using various routes of administration of fibers. It is also generally accepted that the effects of fibers on pulmonary macrophages is central to all fiber-induced pathology, and the release of macrophage-associated inflammatory and immunological mediatros is dealt with in a further chapter. Examination of pathogenicity by cell culture is described, and areas covered include the role of free radicals and cellular mechanisms in producing genetic damage. The fiber-induced activation of some second messenger pathways is also described, with consideration of whether or not similar cellular mechanisms are responsible for all the clinical conditions associated with fiber exposure. Knowledge of the mechanisms involved should be valuable in the development of safe fibers and the prevention of human exposure to new materials that are dangerous as asbestos. The final chapters expound and resolve the conflicts in evidence, discuss the importance of fibers for human well-being and the possible health impact on nonmineral alternatives, and evaluate risks to the public
Author:
Publisher:
ISBN:
Category : Books
Languages : en
Pages : 1886
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Book Description
