Sensitivity Analysis: Matrix Methods in Demography and Ecology

Sensitivity Analysis: Matrix Methods in Demography and Ecology PDF Author: Hal Caswell
Publisher: Springer
ISBN: 3030105342
Category : Social Science
Languages : en
Pages : 308

Get Book Here

Book Description
This open access book shows how to use sensitivity analysis in demography. It presents new methods for individuals, cohorts, and populations, with applications to humans, other animals, and plants. The analyses are based on matrix formulations of age-classified, stage-classified, and multistate population models. Methods are presented for linear and nonlinear, deterministic and stochastic, and time-invariant and time-varying cases. Readers will discover results on the sensitivity of statistics of longevity, life disparity, occupancy times, the net reproductive rate, and statistics of Markov chain models in demography. They will also see applications of sensitivity analysis to population growth rates, stable population structures, reproductive value, equilibria under immigration and nonlinearity, and population cycles. Individual stochasticity is a theme throughout, with a focus that goes beyond expected values to include variances in demographic outcomes. The calculations are easily and accurately implemented in matrix-oriented programming languages such as Matlab or R. Sensitivity analysis will help readers create models to predict the effect of future changes, to evaluate policy effects, and to identify possible evolutionary responses to the environment. Complete with many examples of the application, the book will be of interest to researchers and graduate students in human demography and population biology. The material will also appeal to those in mathematical biology and applied mathematics.

Sensitivity Analysis: Matrix Methods in Demography and Ecology

Sensitivity Analysis: Matrix Methods in Demography and Ecology PDF Author: Hal Caswell
Publisher: Springer
ISBN: 3030105342
Category : Social Science
Languages : en
Pages : 308

Get Book Here

Book Description
This open access book shows how to use sensitivity analysis in demography. It presents new methods for individuals, cohorts, and populations, with applications to humans, other animals, and plants. The analyses are based on matrix formulations of age-classified, stage-classified, and multistate population models. Methods are presented for linear and nonlinear, deterministic and stochastic, and time-invariant and time-varying cases. Readers will discover results on the sensitivity of statistics of longevity, life disparity, occupancy times, the net reproductive rate, and statistics of Markov chain models in demography. They will also see applications of sensitivity analysis to population growth rates, stable population structures, reproductive value, equilibria under immigration and nonlinearity, and population cycles. Individual stochasticity is a theme throughout, with a focus that goes beyond expected values to include variances in demographic outcomes. The calculations are easily and accurately implemented in matrix-oriented programming languages such as Matlab or R. Sensitivity analysis will help readers create models to predict the effect of future changes, to evaluate policy effects, and to identify possible evolutionary responses to the environment. Complete with many examples of the application, the book will be of interest to researchers and graduate students in human demography and population biology. The material will also appeal to those in mathematical biology and applied mathematics.

Fitting Models to Biological Data Using Linear and Nonlinear Regression

Fitting Models to Biological Data Using Linear and Nonlinear Regression PDF Author: Harvey Motulsky
Publisher: Oxford University Press
ISBN: 9780198038344
Category : Mathematics
Languages : en
Pages : 352

Get Book Here

Book Description
Most biologists use nonlinear regression more than any other statistical technique, but there are very few places to learn about curve-fitting. This book, by the author of the very successful Intuitive Biostatistics, addresses this relatively focused need of an extraordinarily broad range of scientists.

Online Optimization of Large Scale Systems

Online Optimization of Large Scale Systems PDF Author: Martin Grötschel
Publisher: Springer Science & Business Media
ISBN: 3662043319
Category : Mathematics
Languages : en
Pages : 789

Get Book Here

Book Description
In its thousands of years of history, mathematics has made an extraordinary ca reer. It started from rules for bookkeeping and computation of areas to become the language of science. Its potential for decision support was fully recognized in the twentieth century only, vitally aided by the evolution of computing and communi cation technology. Mathematical optimization, in particular, has developed into a powerful machinery to help planners. Whether costs are to be reduced, profits to be maximized, or scarce resources to be used wisely, optimization methods are available to guide decision making. Opti mization is particularly strong if precise models of real phenomena and data of high quality are at hand - often yielding reliable automated control and decision proce dures. But what, if the models are soft and not all data are around? Can mathematics help as well? This book addresses such issues, e. g. , problems of the following type: - An elevator cannot know all transportation requests in advance. In which order should it serve the passengers? - Wing profiles of aircrafts influence the fuel consumption. Is it possible to con tinuously adapt the shape of a wing during the flight under rapidly changing conditions? - Robots are designed to accomplish specific tasks as efficiently as possible. But what if a robot navigates in an unknown environment? - Energy demand changes quickly and is not easily predictable over time. Some types of power plants can only react slowly.

Global Sensitivity Analysis

Global Sensitivity Analysis PDF Author: Andrea Saltelli
Publisher: John Wiley & Sons
ISBN: 9780470725177
Category : Mathematics
Languages : en
Pages : 304

Get Book Here

Book Description
Complex mathematical and computational models are used in all areas of society and technology and yet model based science is increasingly contested or refuted, especially when models are applied to controversial themes in domains such as health, the environment or the economy. More stringent standards of proofs are demanded from model-based numbers, especially when these numbers represent potential financial losses, threats to human health or the state of the environment. Quantitative sensitivity analysis is generally agreed to be one such standard. Mathematical models are good at mapping assumptions into inferences. A modeller makes assumptions about laws pertaining to the system, about its status and a plethora of other, often arcane, system variables and internal model settings. To what extent can we rely on the model-based inference when most of these assumptions are fraught with uncertainties? Global Sensitivity Analysis offers an accessible treatment of such problems via quantitative sensitivity analysis, beginning with the first principles and guiding the reader through the full range of recommended practices with a rich set of solved exercises. The text explains the motivation for sensitivity analysis, reviews the required statistical concepts, and provides a guide to potential applications. The book: Provides a self-contained treatment of the subject, allowing readers to learn and practice global sensitivity analysis without further materials. Presents ways to frame the analysis, interpret its results, and avoid potential pitfalls. Features numerous exercises and solved problems to help illustrate the applications. Is authored by leading sensitivity analysis practitioners, combining a range of disciplinary backgrounds. Postgraduate students and practitioners in a wide range of subjects, including statistics, mathematics, engineering, physics, chemistry, environmental sciences, biology, toxicology, actuarial sciences, and econometrics will find much of use here. This book will prove equally valuable to engineers working on risk analysis and to financial analysts concerned with pricing and hedging.

Predictability and Nonlinear Modelling in Natural Sciences and Economics

Predictability and Nonlinear Modelling in Natural Sciences and Economics PDF Author: J. Grasman
Publisher: Springer Science & Business Media
ISBN: 9401109621
Category : Mathematics
Languages : en
Pages : 662

Get Book Here

Book Description
Researchers in the natural sciences are faced with problems that require a novel approach to improve the quality of forecasts of processes that are sensitive to environmental conditions. Nonlinearity of a system may significantly complicate the predictability of future states: a small variation of parameters can dramatically change the dynamics, while sensitive dependence of the initial state may severely limit the predictability horizon. Uncertainties also play a role. This volume addresses such problems by using tools from chaos theory and systems theory, adapted for the analysis of problems in the environmental sciences. Sensitive dependence on the initial state (chaos) and the parameters are analyzed using methods such as Lyapunov exponents and Monte Carlo simulation. Uncertainty in the structure and the values of parameters of a model is studied in relation to processes that depend on the environmental conditions. These methods also apply to biology and economics. For research workers at universities and (semi)governmental institutes for the environment, agriculture, ecology, meteorology and water management, and theoretical economists.

Sensitivity Analysis in Practice

Sensitivity Analysis in Practice PDF Author: Andrea Saltelli
Publisher: John Wiley & Sons
ISBN: 047087094X
Category : Mathematics
Languages : en
Pages : 232

Get Book Here

Book Description
Sensitivity analysis should be considered a pre-requisite for statistical model building in any scientific discipline where modelling takes place. For a non-expert, choosing the method of analysis for their model is complex, and depends on a number of factors. This book guides the non-expert through their problem in order to enable them to choose and apply the most appropriate method. It offers a review of the state-of-the-art in sensitivity analysis, and is suitable for a wide range of practitioners. It is focussed on the use of SIMLAB – a widely distributed freely-available sensitivity analysis software package developed by the authors – for solving problems in sensitivity analysis of statistical models. Other key features: Provides an accessible overview of the current most widely used methods for sensitivity analysis. Opens with a detailed worked example to explain the motivation behind the book. Includes a range of examples to help illustrate the concepts discussed. Focuses on implementation of the methods in the software SIMLAB - a freely-available sensitivity analysis software package developed by the authors. Contains a large number of references to sources for further reading. Authored by the leading authorities on sensitivity analysis.

Nonlinear Modeling and Applications, Volume 2

Nonlinear Modeling and Applications, Volume 2 PDF Author: Tom Proulx
Publisher: Springer Science & Business Media
ISBN: 1441997199
Category : Technology & Engineering
Languages : en
Pages : 186

Get Book Here

Book Description
This the second volume of five from the 28th IMAC on Structural Dynamics and Renewable Energy, 2010, bringing together 17 chapters on Applications of Non-Linear Dynamics. It presents early findings from experimental and computational investigations on Non-Linear Dynamics including studies on Dynamics of a System of Coupled Oscillators with Geometrically Nonlinear Damping, Assigning the Nonlinear Distortions of a Two-input Single-output System, A Multi-harmonic Approach to Updating Locally Nonlinear Structures, A Block Rocking on a Seesawing Foundation, and Enhanced Order Reduction of Forced Nonlinear Systems Using New Ritz Vectors.

Secondary Analysis of Electronic Health Records

Secondary Analysis of Electronic Health Records PDF Author: MIT Critical Data
Publisher: Springer
ISBN: 3319437429
Category : Medical
Languages : en
Pages : 435

Get Book Here

Book Description
This book trains the next generation of scientists representing different disciplines to leverage the data generated during routine patient care. It formulates a more complete lexicon of evidence-based recommendations and support shared, ethical decision making by doctors with their patients. Diagnostic and therapeutic technologies continue to evolve rapidly, and both individual practitioners and clinical teams face increasingly complex ethical decisions. Unfortunately, the current state of medical knowledge does not provide the guidance to make the majority of clinical decisions on the basis of evidence. The present research infrastructure is inefficient and frequently produces unreliable results that cannot be replicated. Even randomized controlled trials (RCTs), the traditional gold standards of the research reliability hierarchy, are not without limitations. They can be costly, labor intensive, and slow, and can return results that are seldom generalizable to every patient population. Furthermore, many pertinent but unresolved clinical and medical systems issues do not seem to have attracted the interest of the research enterprise, which has come to focus instead on cellular and molecular investigations and single-agent (e.g., a drug or device) effects. For clinicians, the end result is a bit of a “data desert” when it comes to making decisions. The new research infrastructure proposed in this book will help the medical profession to make ethically sound and well informed decisions for their patients.

Nonlinear Regression with R

Nonlinear Regression with R PDF Author: Christian Ritz
Publisher: Springer Science & Business Media
ISBN: 0387096167
Category : Mathematics
Languages : en
Pages : 151

Get Book Here

Book Description
- Coherent and unified treatment of nonlinear regression with R. - Example-based approach. - Wide area of application.

The Prevention and Treatment of Missing Data in Clinical Trials

The Prevention and Treatment of Missing Data in Clinical Trials PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 030918651X
Category : Medical
Languages : en
Pages : 163

Get Book Here

Book Description
Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.