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Author: Diana Cole
Publisher: CRC Press
ISBN: 1498720900
Category : Mathematics
Languages : en
Pages : 273
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Book Description
Statistical and mathematical models are defined by parameters that describe different characteristics of those models. Ideally it would be possible to find parameter estimates for every parameter in that model, but, in some cases, this is not possible. For example, two parameters that only ever appear in the model as a product could not be estimated individually; only the product can be estimated. Such a model is said to be parameter redundant, or the parameters are described as non-identifiable. This book explains why parameter redundancy and non-identifiability is a problem and the different methods that can be used for detection, including in a Bayesian context. Key features of this book: Detailed discussion of the problems caused by parameter redundancy and non-identifiability Explanation of the different general methods for detecting parameter redundancy and non-identifiability, including symbolic algebra and numerical methods Chapter on Bayesian identifiability Throughout illustrative examples are used to clearly demonstrate each problem and method. Maple and R code are available for these examples More in-depth focus on the areas of discrete and continuous state-space models and ecological statistics, including methods that have been specifically developed for each of these areas This book is designed to make parameter redundancy and non-identifiability accessible and understandable to a wide audience from masters and PhD students to researchers, from mathematicians and statisticians to practitioners using mathematical or statistical models.
Author: Diana Cole
Publisher: CRC Press
ISBN: 1498720900
Category : Mathematics
Languages : en
Pages : 273
Get Book Here
Book Description
Statistical and mathematical models are defined by parameters that describe different characteristics of those models. Ideally it would be possible to find parameter estimates for every parameter in that model, but, in some cases, this is not possible. For example, two parameters that only ever appear in the model as a product could not be estimated individually; only the product can be estimated. Such a model is said to be parameter redundant, or the parameters are described as non-identifiable. This book explains why parameter redundancy and non-identifiability is a problem and the different methods that can be used for detection, including in a Bayesian context. Key features of this book: Detailed discussion of the problems caused by parameter redundancy and non-identifiability Explanation of the different general methods for detecting parameter redundancy and non-identifiability, including symbolic algebra and numerical methods Chapter on Bayesian identifiability Throughout illustrative examples are used to clearly demonstrate each problem and method. Maple and R code are available for these examples More in-depth focus on the areas of discrete and continuous state-space models and ecological statistics, including methods that have been specifically developed for each of these areas This book is designed to make parameter redundancy and non-identifiability accessible and understandable to a wide audience from masters and PhD students to researchers, from mathematicians and statisticians to practitioners using mathematical or statistical models.
Author: Rachel S. McCrea
Publisher: CRC Press
ISBN: 1439836590
Category : Mathematics
Languages : en
Pages : 316
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Book Description
An important first step in studying the demography of wild animals is to identify the animals uniquely through applying markings, such as rings, tags, and bands. Once the animals are encountered again, researchers can study different forms of capture-recapture data to estimate features, such as the mortality and size of the populations. Capture-recapture methods are also used in other areas, including epidemiology and sociology. With an emphasis on ecology, Analysis of Capture-Recapture Data covers many modern developments of capture-recapture and related models and methods and places them in the historical context of research from the past 100 years. The book presents both classical and Bayesian methods. A range of real data sets motivates and illustrates the material and many examples illustrate biometry and applied statistics at work. In particular, the authors demonstrate several of the modeling approaches using one substantial data set from a population of great cormorants. The book also discusses which computer programs to use for implementing the models and contains 130 exercises that extend the main material. The data sets, computer programs, and other ancillaries are available at www.capturerecapture.co.uk. The book is accessible to advanced undergraduate and higher-level students, quantitative ecologists, and statisticians. It helps readers understand model formulation and applications, including the technicalities of model diagnostics and checking.
Author: Aleš Prokop
Publisher: Springer Science & Business Media
ISBN: 9400768036
Category : Medical
Languages : en
Pages : 569
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Book Description
Growth in the pharmaceutical market has slowed down – almost to a standstill. One reason is that governments and other payers are cutting costs in a faltering world economy. But a more fundamental problem is the failure of major companies to discover, develop and market new drugs. Major drugs losing patent protection or being withdrawn from the market are simply not being replaced by new therapies – the pharmaceutical market model is no longer functioning effectively and most pharmaceutical companies are failing to produce the innovation needed for success. This multi-authored new book looks at a vital strategy which can bring innovation to a market in need of new ideas and new products: Systems Biology (SB). Modeling is a significant task of systems biology. SB aims to develop and use efficient algorithms, data structures, visualization and communication tools to orchestrate the integration of large quantities of biological data with the goal of computer modeling. It involves the use of computer simulations of biological systems, such as the networks of metabolites comprise signal transduction pathways and gene regulatory networks to both analyze and visualize the complex connections of these cellular processes. SB involves a series of operational protocols used for performing research, namely a cycle composed of theoretical, analytic or computational modeling to propose specific testable hypotheses about a biological system, experimental validation, and then using the newly acquired quantitative description of cells or cell processes to refine the computational model or theory.
Author: David L. Thomson
Publisher: Springer Science & Business Media
ISBN: 038778151X
Category : Medical
Languages : en
Pages : 1110
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Book Description
Here, biologists and statisticians come together in an interdisciplinary synthesis with the aim of developing new methods to overcome the most significant challenges and constraints faced by quantitative biologists seeking to model demographic rates.
Author: Michael Schaub
Publisher: Academic Press
ISBN: 0128209151
Category : Science
Languages : en
Pages : 640
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Book Description
Integrated Population Models: Theory and Ecological Applications with R and JAGS is the first book on integrated population models, which constitute a powerful framework for combining multiple data sets from the population and the individual levels to estimate demographic parameters, and population size and trends. These models identify drivers of population dynamics and forecast the composition and trajectory of a population. Written by two population ecologists with expertise on integrated population modeling, this book provides a comprehensive synthesis of the relevant theory of integrated population models with an extensive overview of practical applications, using Bayesian methods by means of case studies. The book contains fully-documented, complete code for fitting all models in the free software, R and JAGS. It also includes all required code for pre- and post-model-fitting analysis. Integrated Population Models is an invaluable reference for researchers and practitioners involved in population analysis, and for graduate-level students in ecology, conservation biology, wildlife management, and related fields. The text is ideal for self-study and advanced graduate-level courses. - Offers practical and accessible ecological applications of IPMs (integrated population models) - Provides full documentation of analyzed code in the Bayesian framework - Written and structured for an easy approach to the subject, especially for non-statisticians
Author: K. B. Newman
Publisher: Springer
ISBN: 1493909770
Category : Medical
Languages : en
Pages : 223
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Book Description
This book gives a unifying framework for estimating the abundance of open populations: populations subject to births, deaths and movement, given imperfect measurements or samples of the populations. The focus is primarily on populations of vertebrates for which dynamics are typically modelled within the framework of an annual cycle, and for which stochastic variability in the demographic processes is usually modest. Discrete-time models are developed in which animals can be assigned to discrete states such as age class, gender, maturity, population (within a metapopulation), or species (for multi-species models). The book goes well beyond estimation of abundance, allowing inference on underlying population processes such as birth or recruitment, survival and movement. This requires the formulation and fitting of population dynamics models. The resulting fitted models yield both estimates of abundance and estimates of parameters characterizing the underlying processes.
Author: Shiyu Zhou
Publisher: John Wiley & Sons
ISBN: 1119666287
Category : Mathematics
Languages : en
Pages : 356
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Book Description
Discover data analytics methodologies for the diagnosis and prognosis of industrial systems under a unified random effects model In Industrial Data Analytics for Diagnosis and Prognosis - A Random Effects Modelling Approach, distinguished engineers Shiyu Zhou and Yong Chen deliver a rigorous and practical introduction to the random effects modeling approach for industrial system diagnosis and prognosis. In the book’s two parts, general statistical concepts and useful theory are described and explained, as are industrial diagnosis and prognosis methods. The accomplished authors describe and model fixed effects, random effects, and variation in univariate and multivariate datasets and cover the application of the random effects approach to diagnosis of variation sources in industrial processes. They offer a detailed performance comparison of different diagnosis methods before moving on to the application of the random effects approach to failure prognosis in industrial processes and systems. In addition to presenting the joint prognosis model, which integrates the survival regression model with the mixed effects regression model, the book also offers readers: A thorough introduction to describing variation of industrial data, including univariate and multivariate random variables and probability distributions Rigorous treatments of the diagnosis of variation sources using PCA pattern matching and the random effects model An exploration of extended mixed effects model, including mixture prior and Kalman filtering approach, for real time prognosis A detailed presentation of Gaussian process model as a flexible approach for the prediction of temporal degradation signals Ideal for senior year undergraduate students and postgraduate students in industrial, manufacturing, mechanical, and electrical engineering, Industrial Data Analytics for Diagnosis and Prognosis is also an indispensable guide for researchers and engineers interested in data analytics methods for system diagnosis and prognosis.
Author: John P. Hoffmann
Publisher: CRC Press
ISBN: 1000437965
Category : Mathematics
Languages : en
Pages : 436
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Book Description
Research in social and behavioral sciences has benefited from linear regression models (LRMs) for decades to identify and understand the associations among a set of explanatory variables and an outcome variable. Linear Regression Models: Applications in R provides you with a comprehensive treatment of these models and indispensable guidance about how to estimate them using the R software environment. After furnishing some background material, the author explains how to estimate simple and multiple LRMs in R, including how to interpret their coefficients and understand their assumptions. Several chapters thoroughly describe these assumptions and explain how to determine whether they are satisfied and how to modify the regression model if they are not. The book also includes chapters on specifying the correct model, adjusting for measurement error, understanding the effects of influential observations, and using the model with multilevel data. The concluding chapter presents an alternative model—logistic regression—designed for binary or two-category outcome variables. The book includes appendices that discuss data management and missing data and provides simulations in R to test model assumptions. Features Furnishes a thorough introduction and detailed information about the linear regression model, including how to understand and interpret its results, test assumptions, and adapt the model when assumptions are not satisfied. Uses numerous graphs in R to illustrate the model’s results, assumptions, and other features. Does not assume a background in calculus or linear algebra, rather, an introductory statistics course and familiarity with elementary algebra are sufficient. Provides many examples using real-world datasets relevant to various academic disciplines. Fully integrates the R software environment in its numerous examples. The book is aimed primarily at advanced undergraduate and graduate students in social, behavioral, health sciences, and related disciplines, taking a first course in linear regression. It could also be used for self-study and would make an excellent reference for any researcher in these fields. The R code and detailed examples provided throughout the book equip the reader with an excellent set of tools for conducting research on numerous social and behavioral phenomena. John P. Hoffmann is a professor of sociology at Brigham Young University where he teaches research methods and applied statistics courses and conducts research on substance use and criminal behavior.
Author: Karl Tuyls
Publisher: Springer Science & Business Media
ISBN: 3540710361
Category : Science
Languages : en
Pages : 190
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Book Description
This book constitutes the thoroughly refereed post-proceedings of the First International Workshop on Knowledge Discovery and Emergent Complexity in Bioinformatics, KDECB 2006, held in Ghent, Belgium, in May 2006, in connection with the 15th Belgium-Netherlands Conference on Machine Learning. The 12 revised full papers cover various topics in the areas of knowledge discovery and emergent complexity research in bioinformatics.
Author: Nathalie Peyrard
Publisher: John Wiley & Sons
ISBN: 1789450470
Category : Social Science
Languages : en
Pages : 258
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Book Description
The study of ecological systems is often impeded by components that escape perfect observation, such as the trajectories of moving animals or the status of plant seed banks. These hidden components can be efficiently handled with statistical modeling by using hidden variables, which are often called latent variables. Notably, the hidden variables framework enables us to model an underlying interaction structure between variables (including random effects in regression models) and perform data clustering, which are useful tools in the analysis of ecological data. This book provides an introduction to hidden variables in ecology, through recent works on statistical modeling as well as on estimation in models with latent variables. All models are illustrated with ecological examples involving different types of latent variables at different scales of organization, from individuals to ecosystems. Readers have access to the data and R codes to facilitate understanding of the model and to adapt inference tools to their own data.
