Organophosphates PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Organophosphates PDF full book. Access full book title Organophosphates by Janice E. Chambers. Download full books in PDF and EPUB format.
Author: Janice E. Chambers
Publisher: Academic Press
ISBN:
Category : Medical
Languages : en
Pages : 472
Get Book Here
Book Description
This volume pulls together a wealth of up-to-date information on the toxicology of this diverse and ubiquitous class of insecticides. Leading experts review the reactivity of organophosphorus compounds with cholinesterase, as well as their metabolism and biological effects on humans and other nontarget organisms. The book not only covers the anticholinesterase actions of organophosphates, but also other, presumably independent, effects, such as teratogenicity, delayed neuropathy, immunotoxicity, and behavioral toxicity. Offers crucial overviews of chemical and biochemical reactivity and biological responsiveness of mainly nontarget organisms Reviews new developments in assessment of metabolism and disposition of organophosphorus compounds Examines organophosphorus compound-induced toxicity mediated by mechanisms other than inhibition of acetylcholinesterase Covers new research on differences in toxicity induced by the variety of organophosphorus Analyzes current controversies on the relevance of certain biochemical parameters in actual organophosphate toxicity in vivo
Author: Janice E. Chambers
Publisher: Academic Press
ISBN:
Category : Medical
Languages : en
Pages : 472
Get Book Here
Book Description
This volume pulls together a wealth of up-to-date information on the toxicology of this diverse and ubiquitous class of insecticides. Leading experts review the reactivity of organophosphorus compounds with cholinesterase, as well as their metabolism and biological effects on humans and other nontarget organisms. The book not only covers the anticholinesterase actions of organophosphates, but also other, presumably independent, effects, such as teratogenicity, delayed neuropathy, immunotoxicity, and behavioral toxicity. Offers crucial overviews of chemical and biochemical reactivity and biological responsiveness of mainly nontarget organisms Reviews new developments in assessment of metabolism and disposition of organophosphorus compounds Examines organophosphorus compound-induced toxicity mediated by mechanisms other than inhibition of acetylcholinesterase Covers new research on differences in toxicity induced by the variety of organophosphorus Analyzes current controversies on the relevance of certain biochemical parameters in actual organophosphate toxicity in vivo
Author: Janice E. Chambers
Publisher: Elsevier
ISBN: 0080917267
Category : Medical
Languages : en
Pages : 462
Get Book Here
Book Description
This volume pulls together a wealth of up-to-date information on the toxicology of this diverse and ubiquitous class of insecticides. Leading experts review the reactivity of organophosphorus compounds with cholinesterase, as well as their metabolism and biological effects on humans and other nontarget organisms. The book not only covers the anticholinesterase actions of organophosphates, but also other, presumably independent, effects, such as teratogenicity, delayed neuropathy, immunotoxicity, and behavioral toxicity. - Offers crucial overviews of chemical and biochemical reactivity and biological responsiveness of mainly nontarget organisms - Reviews new developments in assessment of metabolism and disposition of organophosphorus compounds - Examines organophosphorus compound-induced toxicity mediated by mechanisms other than inhibition of acetylcholinesterase - Covers new research on differences in toxicity induced by the variety of organophosphorus - Analyzes current controversies on the relevance of certain biochemical parameters in actual organophosphate toxicity in vivo
Author: Ramesh C Gupta
Publisher: Academic Press
ISBN: 0080543103
Category : Technology & Engineering
Languages : en
Pages : 781
Get Book Here
Book Description
This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use continues to pose a threat to human and animal health, aquatic systems and wildlife. These anticholinesterase agents produce a variety of toxicological effects in target and nontarget organs. In light of this complexicity, this multi-authored book is written by the well known scientists from many countries. The book is organized into nine sections, with a total of 49 chapters, to provide in-depth knowledge on various aspects of OP and CM compounds, including their use, classification, mechanism-based toxicity, and prophylactic and therapeutic measurements. Several chapters are written with special emphasis to cover timely topics, such as chemical warfare agents, physiologically-based pharmacokinetic modeling, structure and function of cholinesterases, paraoxonase, carboxylesterases; developmental neurotoxicity, the intermediate syndrome, oxidative stress, endocrine disruption, and DNA damage/gene expression and carcinogenesis. Section-VI with 5 chapters is specifically devoted to risk assessment, and safety and regulatory guidelines for pesticides. - Describes everything you need to know about Organophosphates and Carbamates - Extensively covers pesticides, nerve agents, therapeutic drugs, and flame retardants - Describes epidemiology of the world's major disasters involving Organophosphates and Carbamates - Covers animal, human, aquatic, and wildlife toxicity of Anticholinesterases - Insights into in-depth cholinergic and noncholinergic mechanisms of toxicity - Describes recent advancements in cholinesterases, paraoxonases, carboxylesterases, oxidative stress, endocrine disruption, cardiac and pulmonary toxicity, and carcinogenesis - Provides in vitro and in vivo models for neurotoxicity testing - Integrates knowledge of studies in lab animals and humans - Offers risk/safety assessment and national/international guidelines for permissible levels of pesticide residues - Describes management of Anticholinesterase poisoning in humans
Author:
Publisher: Academic Press
ISBN: 0128205156
Category : Science
Languages : en
Pages : 288
Get Book Here
Book Description
Neurotoxicity of Pesticides, Volume Four, in this comprehensive serial addresses contemporary advances in neurotoxicology of pesticides by providing authoritative review articles on key issues in the field. Edited by leading subject experts, topics of note in this new release include Organophosphates, OPs, Nerve agents, Pyrethroids, Neonicotinoids and Formamidines, among others.
Author: George B. Koelle
Publisher: Springer Science & Business Media
ISBN: 3642998755
Category : Medical
Languages : en
Pages : 1228
Get Book Here
Book Description
Although the anticholinesterase (anti-ChE) agents have only limited applica tions in therapy, and from the viewpoint of practical significance they are more appropriately classified as toxic compounds or insecticides than as drugs, in their capacity of pharmacological tools they have few equals. The concept of neuro humoral transmission was originally established largely from experiments in which physostigmine, or eserine, was employed to protect acetylcholine (ACh), the trans mitter of the cholinergic nerves, from rapid hydrolytic destruction by acetyl cholinesterase (AChE) and other cholinesterases (ChE's). Since then, a great num ber of additional reversible and irreversible anti-ChE agents also have been indis pensable in studies of synaptic and neuroeffector transmission, and of other physiological processes. At the same time, there is practically no other class of compounds for which a mechanism of pharmacological action can be described in such concrete biochemical and physiological terms. Consequently, it is not sur prising that a huge literature has developed on these several closely interdependent topics. The assembling anrl proper correlation of this material for the present volume has taken the collaborative efforts of over two dozen . investigators. It iR believed that their contributions to this end will prove invaluable to future in vestigators in providing a ready, inclusive source of established information, in defining areas where further studies are indicated, and in preventing unnecessary duplication of past work. How well these aims have been accomplished will be for time and the reader to judge.
Author:
Publisher:
ISBN:
Category : Chlorpyrifos
Languages : en
Pages : 180
Get Book Here
Book Description
Author: Ramesh C Gupta
Publisher: Academic Press
ISBN: 0128190914
Category : Science
Languages : en
Pages : 1322
Get Book Here
Book Description
Handbook of Toxicology of Chemical Warfare Agents, Third Edition, covers every aspect of deadly toxic chemicals used in conflicts, warfare and terrorism. Including findings from experimental as well as clinical studies, this essential reference offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors and biomarkers, on-site and laboratory analytical methods, decontamination and detoxification procedures, and countermeasures. Expanding on the second edition, Handbook of Toxicology of Chemical Warfare Agents has been completely updated, presenting the most recent advances in field. Brand new chapters include a new chapter on emergency preparedness, coverage of the chemical warfare agents used in Syria, the use of the Novichok agent in the UK, and more. - Unites world-leading experts to bring you cutting-edge, agent-specific information on Chemical Warfare Agents (CWA) and their adverse effects on human and animal health, and the environment - Provides you with all the information you need on CWA modes of action, detection, prevention, therapeutic treatment and countermeasures - New to this edition: a full update to reflect the most recent advances in the field and new chapters on emergency preparedness, the chemical warfare agents used in Syria, and the use of the Novichok agent in the UK
Author: Rachel H. Plattenberg
Publisher: Nova Publishers
ISBN: 9781600212857
Category : Nature
Languages : en
Pages : 324
Get Book Here
Book Description
Pollution is the release of chemical, physical, biological or radioactive contaminants to the environment. Principal forms of pollution include: air pollution, the release of chemicals and particulates into the atmosphere. Common examples include carbon monoxide, sulphur dioxide, chlorofluorocarbons (CFCs), and nitrogen oxides produced by industry and motor vehicles. Ozone and smog are created as nitrogen oxides and hydrocarbons react to sunlight. Water pollution affects oceans and inland bodies of water. Examples include organic and inorganic chemicals, heavy metals, petrochemicals, chloroform, and bacteria. Water pollution may also occur in the form of thermal pollution and the depletion of dissolved oxygen. Soil contamination often occurs when chemicals are released by spill or underground storage tank leakage. Contaminants include hydrocarbons, heavy metals, MTBE, herbicides, pesticides and chlorinated hydrocarbons. Often occurs with water pollution, thanks to surface runoff and groundwater. Radioactive contamination was added in the wake of 20th-century discoveries in atomic physics. Noise pollution encompasses roadway noise, aircraft noise, industrial noise as well as high-intensity sonar. Light pollution, includes light trespass, over-illumination and astronomical interference. Visual pollution, which can refer to the presence of overhead power lines, highway billboards, scarred landforms (as from strip mining), open storage of junk or municipal solid waste. The nature, distribution and ecological effects of all types and forms of pollutants in air, soil and water are the subject of this book.
Author: F. Moriarty
Publisher: Academic Press
ISBN: 0125067631
Category : Science
Languages : en
Pages : 365
Get Book Here
Book Description
Ecotoxicology, Third Edition discusses the ecological effects of pollutants: the ways in which ecosystems can be affected, and current attempts to predict and monitor such effects. The emphasis is on ecosystems; therefore toxicological approaches are critically assessed. Following a brief introduction to the principal characteristics of both pollutants and ecosystems, the various ecosystem components are considered in more detail. Populations, communities and gene pools are examined with an emphasis on the ways in which pollutants affect them specifically. The indirect effects of pollution are considered separately in a new chapter with particular attention paid to the mechanisms and biological effects of global warming. A discussion of the methods used to predict and to monitor the effects of pollutants, some illustrative examples of pollution problems and a final summary discussion, complete the book. A classic proven by its second edition Still the only book to properly integrate ecological principles with chemistry/biochemistry Focuses on the interaction between ecology and toxicology Designed for use by toxicologists with no ecology training, and for ecologists with no toxicology training There is a new chapter on pollutants in habitats and global warming
Author: David M. Whitacre
Publisher: Springer Science & Business Media
ISBN: 1441956239
Category : Science
Languages : en
Pages : 178
Get Book Here
Book Description
Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications.
