Ontogeny of the Mouse Immune System: Immunoglobulin Producing Cells PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Ontogeny of the Mouse Immune System: Immunoglobulin Producing Cells PDF full book. Access full book title Ontogeny of the Mouse Immune System: Immunoglobulin Producing Cells by Marvin L. Tyan. Download full books in PDF and EPUB format.
Author: Marvin L. Tyan
Publisher:
ISBN:
Category :
Languages : en
Pages : 16
Get Book Here
Book Description
When mouse fetal tissues of various ages were transferred to allogeneic or congenic hosts which differed from the immunoglobulin locus Ig 1, it was found that cells which have the potential to differentiate into immunoglobulin producing cells appear in the yolk sac, liver and caudal half of the embryo by the 9th day of gestation. Late in pregnancy these cells are found in the thymus, gut, lung, spleen, femur and peripheral blood. Certain of the data suggest that immunoglobulin producing cell lines and those which mediate cell-bound immune response arise early ingestation as separate cell populations. Further, it was shown that immunoglobulin synthesis per se is independent of the thymus. (Author).
Author: Marvin L. Tyan
Publisher:
ISBN:
Category :
Languages : en
Pages : 16
Get Book Here
Book Description
When mouse fetal tissues of various ages were transferred to allogeneic or congenic hosts which differed from the immunoglobulin locus Ig 1, it was found that cells which have the potential to differentiate into immunoglobulin producing cells appear in the yolk sac, liver and caudal half of the embryo by the 9th day of gestation. Late in pregnancy these cells are found in the thymus, gut, lung, spleen, femur and peripheral blood. Certain of the data suggest that immunoglobulin producing cell lines and those which mediate cell-bound immune response arise early ingestation as separate cell populations. Further, it was shown that immunoglobulin synthesis per se is independent of the thymus. (Author).
Author: M. L. Tyan
Publisher:
ISBN:
Category : Immunology
Languages : en
Pages : 30
Get Book Here
Book Description
The presence of potential immunologically competent cells in the various tissues of embryonic, newborn and adult mice was demonstrated by means of a modified 'graft-vs-host' method and by the injection of chromosomally marked cells into irradiated recipients. The results indicate that lymphoid stem cells which have the potential to participate in cell-bound immune reactions appear in the placenta and liver by the 9th or 10th day of gestation. Throughout pregnancy they are found in the liver. During the 11th to 14th days of gestation these stem cells are present in the upper trunk or in the thymus. On about the 15th day they appear in the lung and toward the end of the pregnancy in the fetal bone marrow and spleen. There was little or no evidence of the presence of lymphoid precursors capable of maturation to cells which mediate cell-bound immune responses in the gut prior to birth. Following parturition lymphoid stem cells were present in the liver, Peyer's patches, lung, bone marrow, lymph nodes, spleen, blood and thymus. However, by six weeks after birth the bone marrow appeared to be the major or sole source of these cells. Certain of the data suggest that immunoglobulin producing cells (as opposed to those which mediate cell-bound immunity) may arise in the yolk sac on the 9th or 10th day of gestation. Further, these immunoglobulin producing cells may reside in the gut as a relatively pure cell population after the 16th day of gestation. (Author).
Author: Yvonne Joy Rosenberg
Publisher:
ISBN:
Category : Antigens
Languages : en
Pages : 234
Get Book Here
Book Description
Author: Edward Stanley Rector
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Get Book Here
Book Description
Author: Kenneth Murphy
Publisher: Garland Science
ISBN: 9780815344575
Category : Medical
Languages : en
Pages :
Get Book Here
Book Description
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author: Pedro A. de Alarcón
Publisher: Cambridge University Press
ISBN: 1108488986
Category : Medical
Languages : en
Pages : 501
Get Book Here
Book Description
An essential guide to the pathogenesis, diagnosis and management of hematologic problems in the neonate, covering erythrocyte disorders, leukocyte disorders, immunologic disorders and hemostatic disorders. Guidance is practical, including blood test interpretation, advice on transfusions and reference ranges for hematological values.
Author: Bernd Kaspers
Publisher: Academic Press
ISBN: 0123972728
Category : Medical
Languages : en
Pages : 456
Get Book Here
Book Description
The second edition of Avian Immunology provides an up-to-date overview of the current knowledge of avian immunology. From the ontogeny of the avian immune system to practical application in vaccinology, the book encompasses all aspects of innate and adaptive immunity in chickens. In addition, chapters are devoted to the immunology of other commercially important species such as turkeys and ducks, and to ecoimmunology summarizing the knowledge of immune responses in free-living birds often in relation to reproductive success. The book contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. The world-wide importance of poultry protein for the human diet, as well as the threat of avian influenza pandemics like H5N1 and heavy reliance on vaccination to protect commercial flocks makes this book a vital resource. This book provides crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology. With contributions from 33 of the foremost international experts in the field, this book provides the most up-to-date review of avian immunology so far Contains a detailed description of the avian innate immune system reviewing constitutive barriers, chemical and cellular responses; it includes a comprehensive review of avian Toll-like receptors Contains a wide-ranging review of the "ecoimmunology" of free-living avian species, as applied to studies of population dynamics, and reviews methods and resources available for carrying out such research
Author: Edward J. Moticka
Publisher: Newnes
ISBN: 0123983754
Category : Medical
Languages : en
Pages : 396
Get Book Here
Book Description
A Historical Perspective on Evidence-Based Immunology focuses on the results of hypothesis-driven, controlled scientific experiments that have led to the current understanding of immunological principles. The text helps beginning students in biomedical disciplines understand the basis of immunologic knowledge, while also helping more advanced students gain further insights. The book serves as a crucial reference for researchers studying the evolution of ideas and scientific methods, including fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, the generation of diversity and mechanism of tolerance of T cells and B cells, the first cytokines, the concept of autoimmunity, the identification of NK cells as a unique cell type, the structure of antibody molecules and identification of Fab and Fc regions, and dendritic cells. Provides a complete review of the hypothesis-driven, controlled scientific experiments that have led to our current understanding of immunological principles Explains the types of experiments that were performed and how the interpretation of the experiments altered the understanding of immunology Presents concepts such as the division of lymphocytes into functionally different populations in their historical context Includes fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, and the generation of diversity and mechanism of tolerance of T and B cells
Author: Marie-Paule Lefranc
Publisher: Elsevier
ISBN: 0080542646
Category : Medical
Languages : en
Pages : 413
Get Book Here
Book Description
The T Cell Receptor FactsBook contains entries on all the 176 functional variable, diversity, joining, and constant regions of the human T cell receptor, including alpha, beta, gamma, and delta loci. Introductory chapters summarize information of T cell receptor chain synthesis, chromosomal location, and an overview of the human T cell receptor loci.
Author: Tasuku Honjo
Publisher: Academic Press
ISBN: 9780123979339
Category : Science
Languages : en
Pages : 0
Get Book Here
Book Description
Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics.
