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Author: Alexander Birbrair
Publisher: Academic Press
ISBN: 0128238836
Category : Science
Languages : en
Pages : 338
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Book Description
The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs - Novel Concepts, Volume 15 addresses how important induced pluripotent stems cells are and how can they can help treat certain diseases. Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how induced pluripotent stem cells are being used for treatment of different disorders, such as liver disease, type-1 diabetes, Parkinson's disease, macular degeneration of the retina and much more. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. - Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics - Covers spinal cord injuries, type-1 diabetes, liver disease, Parkinson's disease, graft vs. host disease, and much more - Contributed by world-renown experts in the field
Author: Alexander Birbrair
Publisher: Academic Press
ISBN: 0128238836
Category : Science
Languages : en
Pages : 338
Get Book Here
Book Description
The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs - Novel Concepts, Volume 15 addresses how important induced pluripotent stems cells are and how can they can help treat certain diseases. Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how induced pluripotent stem cells are being used for treatment of different disorders, such as liver disease, type-1 diabetes, Parkinson's disease, macular degeneration of the retina and much more. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. - Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics - Covers spinal cord injuries, type-1 diabetes, liver disease, Parkinson's disease, graft vs. host disease, and much more - Contributed by world-renown experts in the field
Author: Alexander Birbrair
Publisher: Academic Press
ISBN: 0128222301
Category : Science
Languages : en
Pages : 282
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Book Description
The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology.Recent Advances in iPSC-derived Cell Types, Volume 4 addresses how different cell types can be derived from induced pluripotent stem cells.Somatic cells can be reprogrammed into Induced pluripotent stem cells by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. The volume teaches readers about current advances in the field. This book describes the use of induced pluripotent stem cells to form different cell types which can be used in cell therapy as well as to model several diseases in vitro, enabling us to study the cellular and molecular mechanisms involved in different pathologies. In recent years, remarkable progress has been made in the obtention of induced pluripotent stem cells and their differentiation into several cellular populations, tissues and organs using state-of-art techniques. This volume will cover what we know so far about the use of iPSCs to derive different cell types, such as: erythroid cells, mucosal-associated invariant T cells, megakaryocytes, cerebral cortical neurons, inner ear cell types, airway epithelial cells, male germ cells, trophoblasts, cardiomyocytes, ßpancreatic cells, and more. The volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and organ transplantation; and is contributed by world-renowned authors in the field.
Author: Anthony Atala
Publisher: Academic Press
ISBN: 0123814235
Category : Science
Languages : en
Pages : 1203
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Book Description
Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. - Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology - The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine - New discoveries from leading researchers on restoration of diseased tissues and organs
Author: Alexander Birbrair
Publisher: Springer
ISBN: 3030110966
Category : Science
Languages : en
Pages : 233
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Book Description
This book presents a comprehensive discussion on the novel concepts in stem cell heterogeneity, from pluripotent stem cells to human mesenchymal stem cells, adult and cancer stem cells of the thyroid, sarcoma, and more. Thus, Stem Cell Heterogeneity - Novel Concepts starts from a timely update on the current information on stem cells heterogeneity in various tissues and discusses new concepts and future directions. It also provides a solid foundation of the history of stem cells from specific tissues and the current applications of this knowledge in regenerative medicine. When taken as a whole, alongside its companion volumes Stem Cells Heterogeneity in Different Organs, and Stem Cells Heterogeneity in Cancer, these three books present a comprehensive reference on stem cell heterogeneity in various tissues and current and future applications for regenerative medicine. It is essential reading for advanced cell biology students as well as researchers in stem cells and clinicians.
Author: Carlos Simón
Publisher: Cambridge University Press
ISBN: 1107034477
Category : Medical
Languages : en
Pages : 199
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Book Description
Stem cell science has the potential to impact human reproductive medicine significantly - cutting edge technologies allow the production and regeneration of viable gametes from human stem cells offering potential to preciously infertile patients. Written by leading experts in the field Stem Cells in Reproductive Medicine brings together chapters on the genetics and epigenetics of both the male and female gametes as well as advice on the production and regeneration of gene cells in men and women, trophoblasts and endometrium from human embryonic and adult stem cells. Although focussing mainly on the practical elements of the use of stem cells in reproductive medicine, the book also contains a section on new developments in stem cell research. The book is essential reading for reproductive medicine clinicians, gynecologists and embryologists who want to keep abreast of practical developments in this rapidly developing field.
Author: Keiichi Fukuda
Publisher: Springer
ISBN: 4431559663
Category : Science
Languages : en
Pages : 102
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Book Description
Human iPS cells have a great potential to be cell sources for regenerative medicine because of the promise of infinite self-renewal and the capability to differentiate into multiple cell types. This book focuses on another great potential of human iPS cells, which is the establishment of human disease models using patient-specific iPS cells. Human iPS cells can be easily obtained from a patient’s somatic cells and provide the entire information on the patient’s genome. Accordingly, we can generate disease models for inheritable diseases in cell culture dishes using iPS cells. This is a quite new technique but holds tremendous potential for our increased understanding of pathogenesis, and will then be the basis for novel drug development industries. All the authors are leading researchers in this field and they have reported many kinds of patient-derived iPS cells. In this book, they introduce the aspects that could be recapitulated in terms of disease modelling as well as further innovative findings such as novel pathogenetic insights and novel therapies.
Author: Suzanne Peterson
Publisher: Academic Press
ISBN: 0123854741
Category : Science
Languages : en
Pages : 652
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Book Description
This manual is a comprehensive compilation of "methods that work" for deriving, characterizing, and differentiating hPSCs, written by the researchers who developed and tested the methods and use them every day in their laboratories. The manual is much more than a collection of recipes; it is intended to spark the interest of scientists in areas of stem cell biology that they may not have considered to be important to their work. The second edition of the Human Stem Cell Manual is an extraordinary laboratory guide for both experienced stem cell researchers and those just beginning to use stem cells in their work. - Offers a comprehensive guide for medical and biology researchers who want to use stem cells for basic research, disease modeling, drug development, and cell therapy applications - Provides a cohesive global view of the current state of stem cell research, with chapters written by pioneering stem cell researchers in Asia, Europe, and North America - Includes new chapters devoted to recently developed methods, such as iPSC technology, written by the scientists who made these breakthroughs
Author: Alexander Birbrair
Publisher: Elsevier
ISBN: 0323857671
Category : Science
Languages : en
Pages : 316
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Book Description
iPSCs - State of the Science, Volume Sixteen, the latest release in the Advances in Stem Cell Biology series, is an expansive collection of information and new discoveries in the field. This volume addresses the importance of induced pluripotent stems cells and how can they be derived from different sources. It addresses advances in research in induced pluripotent stem cells from alternate sources, such as spermatogonial stem cells, ovarian tissue, cancer cells, and many other sources. It is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors. Provides an overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers iPSCs derived from amniotic fluid, oral tissue derived iPSCs, muse cells, postmortem tissue, and much more Contributed by world-renowned experts in the field
Author: Alexander Birbrair
Publisher: Academic Press
ISBN: 0323900607
Category : Science
Languages : en
Pages : 438
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Book Description
The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology.Molecular Players in iPSC Technology, Volume 12 addresses the molecular players underlying induced pluripotent stem cell (iPSC) generation, maintenance, expansion, and differentiation. The discovery of iPSCs revolutionized biomedical research. iPSC technology involves multiple molecular mechanisms. This volume covers exosomal microRNAs, auxiliary pluripotency-associated genes, inducible caspase-9 suicide gene, cell cycle proteins, ion channels, Notch signaling, kinase signaling, SOCS3/JAK2/STAT3 pathway, NANOG, Krüppel-like factors, H1FOO, and much more in iPSCs. The volume is written for researchers and scientists in stem cell therapy, cellular and molecular biology, and regenerative medicine and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of iPSC technology, regenerative medicine, and therapeutics Covers the different key molecular players involved in iPSC formation, maintenance, expansion, and differentiation Is contributed by world-renowned experts in the field
Author: Alexander Birbrair
Publisher: Elsevier
ISBN: 0323998925
Category : Science
Languages : en
Pages : 636
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Book Description
Current Topics in iPSCs provides a deep analysis of the underlying fundamentals that support short and mid-term developments and milestones in the business of mesenchymal stem cell therapies. This volume explores the next frontier of MSC therapies and how the transformational potential of therapeutic adult cells will be realised in all therapy areas. The impacts of clinical and economic benefits are dissected throughout each of the chapters. Written by thought leaders in the field for those curious about the interface of science and business. Explores the strategy at the forefront of the science of mesenchymal stem cells Provides an overview of all therapy areas where MSC and MSC-derived products can be used therapeutically Depicts transformational changes in healthcare that enable the implementation of MSC-powered technology platforms
