Novel Antibacterial Biomaterials for Medical Applications and Modeling of Drug Release Process

Novel Antibacterial Biomaterials for Medical Applications and Modeling of Drug Release Process PDF Author: Vesna Mišković-Stanković
Publisher: CRC Press
ISBN: 1040035973
Category : Technology & Engineering
Languages : en
Pages : 284

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Book Description
This book provides a comprehensive review of synthesis and physicochemical and biological characterization of novel antibacterial biomaterials produced according to original procedures and aimed at medical applications such as wound dressing, soft and hard tissue implants, drug delivery devices, and carriers for cell cultivation. It is intended for all researchers working in the fields of biomaterials and biomedical engineering, as well as medical professionals, science and engineering graduate students, academics, and industrial researchers. Includes in-depth discussions on synthesis and physicochemical characterization of novel poly vinyl alcohol-based hydrogels aimed at wound dressings and soft tissue implants Explores synthesis and physicochemical characterization of novel bioceramic hydroxyapatite-based coatings on metal surface aimed for hard tissue implants Reviews cytotoxicity and antibacterial activity of novel poly vinyl alcohol-based hydrogels aimed for wound dressing and soft tissue implants Discusses cytotoxicity and antibacterial activity of bioceramic hydroxyapatite-based coatings on metal surface aimed for hard tissue implants Provides original fractional derivative models of drug release process from hydrogels and bioceramic coatings on metal surface and explores diffusion mechanism

Novel Antibacterial Biomaterials for Medical Applications and Modeling of Drug Release Process

Novel Antibacterial Biomaterials for Medical Applications and Modeling of Drug Release Process PDF Author: Vesna Mišković-Stanković
Publisher:
ISBN: 9781032668871
Category :
Languages : en
Pages : 0

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Book Description
"This book provides a comprehensive review of synthesis and physicochemical and biological characterization of novel antibacterial biomaterials produced according to original procedures and aimed at medical applications such as wound dressing, soft and hard tissue implants, drug delivery devices and carriers for cell cultivation. This book is intended for all researchers working in the fields of biomaterials and biomedical engineering, as well as medical professionals, science and engineering graduate students, academics, and industrial researchers"--

Novel Antibacterial Biomaterials for Medical Applications and Modeling of Drug Release Process

Novel Antibacterial Biomaterials for Medical Applications and Modeling of Drug Release Process PDF Author: Vesna Mišković-Stanković
Publisher: CRC Press
ISBN: 1040035973
Category : Technology & Engineering
Languages : en
Pages : 284

Get Book

Book Description
This book provides a comprehensive review of synthesis and physicochemical and biological characterization of novel antibacterial biomaterials produced according to original procedures and aimed at medical applications such as wound dressing, soft and hard tissue implants, drug delivery devices, and carriers for cell cultivation. It is intended for all researchers working in the fields of biomaterials and biomedical engineering, as well as medical professionals, science and engineering graduate students, academics, and industrial researchers. Includes in-depth discussions on synthesis and physicochemical characterization of novel poly vinyl alcohol-based hydrogels aimed at wound dressings and soft tissue implants Explores synthesis and physicochemical characterization of novel bioceramic hydroxyapatite-based coatings on metal surface aimed for hard tissue implants Reviews cytotoxicity and antibacterial activity of novel poly vinyl alcohol-based hydrogels aimed for wound dressing and soft tissue implants Discusses cytotoxicity and antibacterial activity of bioceramic hydroxyapatite-based coatings on metal surface aimed for hard tissue implants Provides original fractional derivative models of drug release process from hydrogels and bioceramic coatings on metal surface and explores diffusion mechanism

Antimicrobial Materials for Biomedical Applications

Antimicrobial Materials for Biomedical Applications PDF Author: Abraham J Domb
Publisher: Royal Society of Chemistry
ISBN: 1788011880
Category : Technology & Engineering
Languages : en
Pages : 546

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Book Description
With the need to combat emerging infectious diseases, research around antimicrobial biomaterials and their applications is booming. This book provides the field with a much-needed fundamental overview of the science, addressing the chemistry of a broad range of biomaterial types, and their applications in the biomedical industry. Materials covered include polymers, from those with inherent antimicrobial activity to those that release antimicrobial agents, antimicrobial ceramics and inorganic compounds, such as metal based antimicrobial additives, and the developing field of biomimetic materials, are discussed. Surfaces, coatings and adhesives are covered, whilst the applications of these antimicrobial materials in biomedical applications, from catheters to orthopaedics, dentistry to ophthalmology, are explored. Edited by international leaders and with contributions from the best in the field, this book is the go-to resource for graduates and researchers in biomaterials science, biomedical engineering, chemical engineering, and materials and polymer chemistry.

Advanced Antimicrobial Materials and Applications

Advanced Antimicrobial Materials and Applications PDF Author: Inamuddin
Publisher: Springer
ISBN: 9789811570971
Category : Science
Languages : en
Pages : 0

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Book Description
Surface bio-contamination has become a severe problem that contributes to outbreaks of community acquired and nosocomial infections through contiguous fomite transmission of diseases. Every year, thousands of patients die due to nosocomial infections by pathogens. It is therefore essential to develop novel strategies to prevent or improve the treatment of biomaterial concomitant infections. The concept of antimicrobial materials is becoming increasingly important not only in the hospital and healthcare environments, but also for laboratories, home appliances, and certain industrial applications. Materials are now being developed to prevent the buildup, spread and transfer of harmful microbes, and to dynamically deactivate them. Drawing on research and examples from around the world, this book highlights the latest advances in, and applications of, antibacterial biomaterials for biomedical devices, and focuses on metals with antibacterial coatings/surfaces, antibacterial stainless steels and other commonly used antibacterial materials. It also discusses the role of innovative approaches and provides a comprehensive overview of cutting-edge research on the processing, properties and technologies involved in the development of antimicrobial applications. Given its scope, the book will be of interest to researchers and policymakers, as well as undergraduate and graduate students of biochemistry, microbiology, and environmental chemistry

Functional Biomaterials

Functional Biomaterials PDF Author: Sougata Jana
Publisher: Springer
ISBN: 9789811671548
Category : Science
Languages : en
Pages : 0

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Book Description
This book explores in depth a wide range of functional biomaterials-based systems for drug, gene delivery, and biomedical aspects. The chapters cover newer technologies such as polymeric micelle, pH-responsive biomaterials, stimuli-responsive hydrogels, silk fibroin, inorganic biomaterials, synthetic biomaterials, 3D printed biomaterials, metallic biomaterials, ceramic and hybrid biomaterials. It also describes the theranostic approaches for cancer therapy, the biomaterials-based nanofibers scaffolds in tissue engineering, as well as the strategies applications of metallic biomaterials for the medical and dental prosthetic field. This newer and updated approach will be attractive for biomedical engineering students working on materials science in the development of novel drug delivery strategies. The book will be an important reference for researchers and professionals working on biomaterial research in the pharmaceutical and medical fields.

Strategies to Modify the Drug Release from Pharmaceutical Systems

Strategies to Modify the Drug Release from Pharmaceutical Systems PDF Author: Marcos Luciano Bruschi
Publisher: Woodhead Publishing
ISBN: 0081001126
Category : Medical
Languages : en
Pages : 208

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Book Description
Since the earliest dosage forms to modern drug delivery systems, came a great development and growth of knowledge with respect to drug delivery. Strategies to Modify the Drug Release from Pharmaceutical Systems will address principles, systems, applications and advances in the field.It will be principally a textbook and a reference source of strategies to modify the drug release. Moreover, the characterization, mathematical and physicochemical models, applications and the systems will be discussed. Addresses the principles, systems, applications and advances in the field of drug delivery Highlights the mathematical and physicochemical principles related to strategies Discusses drug release and its possible modifications

Nanostructures for Antimicrobial Therapy

Nanostructures for Antimicrobial Therapy PDF Author: Anton Ficai
Publisher: Elsevier
ISBN: 0323461514
Category : Medical
Languages : en
Pages : 722

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Book Description
Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. Shows how nanoantibiotics can be used to more effectively treat disease Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area

Handbook of Bioceramics and Biocomposites

Handbook of Bioceramics and Biocomposites PDF Author: Iulian Vasile Antoniac
Publisher: Springer
ISBN: 9783319124599
Category : Technology & Engineering
Languages : en
Pages : 0

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Book Description
This handbook describes several current trends in the development of bioceramics and biocomposites for clinical use in the repair, remodelling, and regeneration of bone tissue. Comprehensive coverage of these materials allows fundamental aspects of the science and engineering to be seen in close relation to the clinical performance of dental and orthopaedic implants. Bioceramics and biocomposites appear to be the most dynamic area of materials development for both tissue engineering and implantable medical devices. Almost all medical specialties will continue to benefit from these developments, but especially dentistry and orthopaedics. In this Handbook, leading researchers describe the use of bionanomaterials to create new functionalities when interfaced with biological molecules or structures. Also described are technologies for bioceramics and biocomposites processing in order to fabricate medical devices for clinical use. Another important section of the book is dedicated to tissue regeneration with development of new matrices. A targeted or personalized treatment device reduces drug consumption and treatment expenses, resulting in benefits to the patient and cost reductions for public health systems. This authoritative reference on the state-of-the-art in the development and use of bioceramics and biocomposites can also serve as the basis of instructional course lectures for audiences ranging from advanced undergraduate students to post-graduates in materials science and engineering and biomedical engineering.

3D Printing of Pharmaceuticals

3D Printing of Pharmaceuticals PDF Author: Abdul W. Basit
Publisher: Springer
ISBN: 3319907557
Category : Medical
Languages : en
Pages : 240

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Book Description
3D printing is forecast to revolutionise the pharmaceutical sector, changing the face of medicine development, manufacture and use. Potential applications range from pre-clinical drug development and dosage form design through to the fabrication of functionalised implants and regenerative medicine. Within clinical pharmacy practice, printing technologies may finally lead to the concept of personalised medicines becoming a reality. This volume aims to be the definitive resource for anyone thinking of developing or using 3D printing technologies in the pharmaceutical sector, with a strong focus on the translation of printing technologies to a clinical setting. This text brings together leading experts to provide extensive information on an array of 3D printing techniques, reviewing the current printing technologies in the pharmaceutical manufacturing supply chain, in particular, highlighting the state-of-the-art applications in medicine and discussing modern drug product manufacture from a regulatory perspective. This book is a highly valuable resource for a range of demographics, including academic researchers and the pharmaceutical industry, providing a comprehensive inventory detailing the current and future applications of 3D printing in pharmaceuticals. Abdul W. Basit is Professor of Pharmaceutics at the UCL School of Pharmacy, University College London. Abdul’s research sits at the interface between pharmaceutical science and gastroenterology, forging links between basic science and clinical outcomes. He leads a large and multidisciplinary research group, and the goal of his work is to further the understanding of gastrointestinal physiology by fundamental research. So far, this knowledge has been translated into the design of new technologies and improved disease treatments, many of which are currently in late-stage clinical trials. He has published over 350 papers, book chapters and abstracts and delivered more than 250 invited research presentations. Abdul is also a serial entrepreneur and has filed 25 patents and founded 3 pharmaceutical companies (Kuecept, Intract Pharma, FabRx). Abdul is a frequent speaker at international conferences, serves as a consultant to many pharmaceutical companies and is on the advisory boards of scientific journals, healthcare organisations and charitable bodies. He is the European Editor of the International Journal of Pharmaceutics. Abdul was the recipient of the Young Investigator Award in Pharmaceutics and Pharmaceutical Technology from the American Association of Pharmaceutical Scientists (AAPS) and is the only non-North American scientist to receive this award. He was also the recipient of the Academy of Pharmaceutical Sciences (APS) award. Simon Gaisford holds a Chair in Pharmaceutics and is Head of the Department of Pharmaceutics at the UCL School of Pharmacy, University College London. He has published 110 papers, 8 book chapters and 4 authored books. His research is focused on novel technologies for manufacturing medicines, particularly using ink-jet printing and 3D printing, and he is an expert in the physico-chemical characterisation of compounds and formulations with thermal methods and calorimetry.

Silk-based Drug Delivery Systems

Silk-based Drug Delivery Systems PDF Author: Elia Bari
Publisher: Royal Society of Chemistry
ISBN: 1788017722
Category : Science
Languages : en
Pages : 243

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Book Description
Covering spider silk and silk worm cocoons, the editors elucidate the extraction, structure and properties of silk sericin and silk fibroin.