Lung Cancer

Lung Cancer PDF Author: Karen L. Reckamp
Publisher: Springer
ISBN: 3319403893
Category : Medical
Languages : en
Pages : 324

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Book Description
This book describes the molecular mechanisms of lung cancer development and progression that determine therapeutic interventions in the era of genomics, when the rapid evolution in lung cancer diagnosis and treatment necessitates critical review of new results to integrate advances into practice. The text opens with background and emerging information regarding the molecular biology of lung cancer pathogenesis. Updated results regarding lung cancer prevention and screening are discussed, followed by chapters on diagnostic techniques and pathological evaluation. This leads on to a detailed presentation of treatment modalities, from surgery and radiation therapy to standard chemotherapy and targeted agents. The coverage includes resistance to therapy and the emergence of immunotherapy for lung cancer; in addition, the current evidence in respect of small cell lung cancer is summarized. The book presents insights from experts across disciplines to emphasize the importance of collaborative care. Advances in our understanding of issues in geriatric oncology and palliative care complete the comprehensive discussion of lung cancer.

Lung Cancer

Lung Cancer PDF Author: Karen L. Reckamp
Publisher: Springer
ISBN: 3319403893
Category : Medical
Languages : en
Pages : 324

Get Book Here

Book Description
This book describes the molecular mechanisms of lung cancer development and progression that determine therapeutic interventions in the era of genomics, when the rapid evolution in lung cancer diagnosis and treatment necessitates critical review of new results to integrate advances into practice. The text opens with background and emerging information regarding the molecular biology of lung cancer pathogenesis. Updated results regarding lung cancer prevention and screening are discussed, followed by chapters on diagnostic techniques and pathological evaluation. This leads on to a detailed presentation of treatment modalities, from surgery and radiation therapy to standard chemotherapy and targeted agents. The coverage includes resistance to therapy and the emergence of immunotherapy for lung cancer; in addition, the current evidence in respect of small cell lung cancer is summarized. The book presents insights from experts across disciplines to emphasize the importance of collaborative care. Advances in our understanding of issues in geriatric oncology and palliative care complete the comprehensive discussion of lung cancer.

Lung Cancer:

Lung Cancer: PDF Author: David J. Stewart
Publisher: Springer Science & Business Media
ISBN: 160761524X
Category : Medical
Languages : en
Pages : 544

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Book Description
Defining the Lung Cancer Problem 1 Lung cancer is the leading cause of cancer death in the world. It kills almost as many Americans as cancers of the breast, prostate, colon, rectum, pancreas, and 2 kidney combined, and accounts for 28.6% of all US cancer deaths. With an increase in the 5-year relative survival rate from 13% to only 16% in the more than 2 30 years from 1974 to the present, it will take us another 840 years to eradicate lung cancer deaths if we do not improve the current rate of progress. As discussed in this text, lung cancer prevention has received substantial att- tion. The decrease in smoking in recent decades has helped, but smoking is not the only problem. Lung cancer in people who have never smoked is currently the 5th 3 leading cause of cancer death in the United States. Several factors contribute to the lethality of lung cancer, including the rapidity of tumor growth, advanced stage at diagnosis (due to nonspecificity of early sy- toms and the uncertain efficacy of screening), early development of metastases, and resistance to therapy. Several chapters in this book discuss new molecular targets that may be potentially exploitable in the future, as well as discussing our track record to date in exploiting them.

Non-Small Cell Lung Cancer: Prevention, Management and Emerging Therapies

Non-Small Cell Lung Cancer: Prevention, Management and Emerging Therapies PDF Author: Rex White
Publisher: American Medical Publishers
ISBN:
Category : Health & Fitness
Languages : en
Pages : 0

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Book Description
Non-small cell lung cancer refers to a disease in which the cancer cells are formed in tissues of the lung. There are three common types of non-small cell lung cancer, namely, adenocarcinoma, squamous cell carcinoma and large cell carcinoma. Smoking cigars, pipes or cigarettes is the major cause of this disease. Radiation therapy, air pollution and pulmonary fibrosis are some other causes of non-small cell lung cancer. Some common symptoms of non-small cell lung cancer are chest pain, appetite loss, unexplained weight loss, tiredness, and swelling of face or the veins in the neck. Patients can be examined by certain diagnostic tests, like chest X-rays, blood or urine tests, sputum cytology, bronchoscopy, etc. Surgery is the major treatment for non-small cell lung cancer. Some other treatments include radiofrequency ablation, chemotherapy, and targeted drug therapy. This book provides comprehensive insights into the prevention, management and emerging therapies for non-small cell lung cancer. It presents researches and studies performed by experts across the globe. This book will prove to be immensely beneficial to students and researchers studying this medical condition.

Molecular Pathology of Lung Cancer

Molecular Pathology of Lung Cancer PDF Author: Philip T. Cagle
Publisher: Springer Science & Business Media
ISBN: 1461431972
Category : Medical
Languages : en
Pages : 217

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Book Description
As with other books in the Molecular Pathology Library Series, Molecular Pathology of Lung Cancer bridges the gap between the molecular specialist and the clinical practitioner, including the surgical pathologist who now has a key role in decisions regarding molecular targeted therapy for lung cancer. Molecular Pathology of Lung Cancer provides the latest information and current insights into the molecular basis for lung cancer, including precursor and preinvasive lesions, molecular diagnosis, molecular targeted therapy, molecular prognosis, molecular radiology and related fields for lung cancer generally and for the specific cell types. As many fundamental concepts about lung cancer have undergone revision in only the past few years, this book will likely be the first to comprehensively cover the new molecular pathology of lung cancer. It provides a foundation in this field for pathologists, medical oncologists, radiation oncologists, thoracic surgeons, thoracic radiologists and their trainees, physician assistants, and nursing staff.

Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer

Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer PDF Author: Prashant Kesharwani
Publisher: Academic Press
ISBN: 0128163674
Category : Medical
Languages : en
Pages : 352

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Book Description
Nanotechnology-based Targeted Drug Delivery Systems for Lung Cancer is an indispensable resource that will help pharmaceutical scientists and clinical researchers design and develop novel drug delivery systems and devices for the treatment of lung cancer. As recent breakthroughs in nanomedicine are now making it possible to deliver drugs, genes and therapeutic agents to localized areas of disease to maximize clinical benefit, while also limiting unwanted side effects, this book explores promising approaches for the diagnosis and treatment of lung cancer using cutting-edge nanomedical technologies. Topics discussed include polymeric nanoparticles, solid lipid nanoparticles, liposomes, dendrimers, micelles and nanoemulsions. - Provides an overview of an array of nanotechnology-based drug delivery systems - Examines the design, synthesis and application of different nanocarriers in drug and gene delivery - Provides an in-depth understanding of the design of targeted nanotherapeutics and technologies and its implication in various site-specific cancers

Diagnosis and Treatment of Lung Cancer

Diagnosis and Treatment of Lung Cancer PDF Author: Frank C. Detterbeck
Publisher: Saunders
ISBN:
Category : Medical
Languages : en
Pages : 512

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Book Description
Access comprehensive, multidisciplinary guidance on the diagnosis and treatment of lung cancer! This new resource addresses the full range of clinical issues in diagnosis, staging, and treatment, as well as the latest scientific data and evidence-based guidelines. A user-friendlyorganization provides quick reference to data summaries, as well as more comprehensive and detailed information for readers who wish to explore topics in depth. Features contributions by authors from many different disciplines, to ensure a balanced approach. Addresses the clinical issues seen in practice, with the inclusion of basic science research topics that are likely to be put into clinical practice soon. Integrates evidence-based medicine throughout. Assesses the strength of all available dataenabling readers to weigh different arguments and make decisions based on medical issues, values, and the availability and efficacy of interventionsusing a data rating system. Addresses difficult, but clinically relevant issues for which limited data is available. Enables readers to quickly reference findings and data in data summary statements and summary tables.

Advanced Drug Delivery Systems in the Management of Cancer

Advanced Drug Delivery Systems in the Management of Cancer PDF Author: Kamal Dua
Publisher: Elsevier
ISBN: 0323900798
Category : Science
Languages : en
Pages : 574

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Book Description
Advanced Drug Delivery Systems in the Management of Cancer discusses recent developments in nanomedicine and nano-based drug delivery systems used in the treatment of cancers affecting the blood, lungs, brain, and kidneys. The research presented in this book includes international collaborations in the area of novel drug delivery for the treatment of cancer. Cancer therapy remains one of the greatest challenges in modern medicine, as successful treatment requires the elimination of malignant cells that are closely related to normal cells within the body. Advanced drug delivery systems are carriers for a wide range of pharmacotherapies used in many applications, including cancer treatment. The use of such carrier systems in cancer treatment is growing rapidly as they help overcome the limitations associated with conventional drug delivery systems. Some of the conventional limitations that these advanced drug delivery systems help overcome include nonspecific targeting, systemic toxicity, poor oral bioavailability, reduced efficacy, and low therapeutic index. This book begins with a brief introduction to cancer biology. This is followed by an overview of the current landscape in pharmacotherapy for the cancer management. The need for advanced drug delivery systems in oncology and cancer treatment is established, and the systems that can be used for several specific cancers are discussed. Several chapters of the book are devoted to discussing the latest technologies and advances in nanotechnology. These include practical solutions on how to design a more effective nanocarrier for the drugs used in cancer therapeutics. Each chapter is written with the goal of informing readers about the latest advancements in drug delivery system technologies while reinforcing understanding through various detailed tables, figures, and illustrations. Advanced Drug Delivery Systems in the Management of Cancer is a valuable resource for anyone working in the fields of cancer biology and drug delivery, whether in academia, research, or industry. The book will be especially useful for researchers in drug formulation and drug delivery as well as for biological and translational researchers working in the field of cancer. - Presents an overview of the recent perspectives and challenges within the management and diagnosis of cancer - Provides insights into how advanced drug delivery systems can effectively be used in the management of a wide range of cancers - Includes up-to-date information on diagnostic methods and treatment strategies using controlled drug delivery systems

60 Years of Survival Outcomes at The University of Texas MD Anderson Cancer Center

60 Years of Survival Outcomes at The University of Texas MD Anderson Cancer Center PDF Author: M. Alma Rodriguez
Publisher: Springer Science & Business Media
ISBN: 1461451973
Category : Medical
Languages : en
Pages : 343

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Book Description
This unique book provides a retrospective analysis of the changes in survival outcomes at the University of Texas, M.D. Anderson Cancer Center over the past six decades. Since opening its doors in 1944, M.D. Anderson has kept a continuous, uninterrupted data repository of the treatment and outcomes of each of its patients. It is this visionary database from the center’s tumor registry which makes this groundbreaking book possible. Tracking results across time, this book shows radical shifts in outcomes trends, where great progress has been made, and where there is still a long way to go, and offers a snapshot into the parallel history of developments in care. Such data is crucial to informing how patients are counseled, how treatment decisions are determined, and how prognoses are made. 60 Years of Survival Outcomes at the University of Texas, M.D. Anderson Cancer Center is the only book to concurrently present longitudinal data on survival outcomes across the spectrum of rare and common cancers. Each chapter deals with a specific disease site, discussing current management approaches and presenting key data replete with illustrative charts, graphs, and tables. With the resources available only to the practitioners at this inimitable institution, this book heralds a cornerstone moment in the study of survival outcomes and the depth of our knowledge of cancer care.

Geriatric Psycho-Oncology

Geriatric Psycho-Oncology PDF Author: Jimmie C. Holland
Publisher: Apos Clinical Reference Handbo
ISBN: 0199361460
Category : Medical
Languages : en
Pages : 225

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Book Description
Geriatric Psycho-Oncology is a comprehensive handbook that provides best practice models for the management of psychological, cognitive, and social outcomes of older adults living with cancer and their families. Chapters cover a wide range of topics including screening tools and interventions, psychiatric emergencies and disorders, physical symptom management, communication issues, and issues specific to common cancer sites. A resource section is appended to provide information on national services and programs. This book features contributions from experts designed to help clinicians review, anticipate and respond to emotional issues that often arise in the context of treating older cancer patients. Numerous cross-references and succinct tables and figures make this concise reference easy to use. Geriatric Psycho-Oncology is an ideal resource for helping oncologists and nurses recognize when it may be best to refer patients to their mental health colleagues and for those who are establishing or adding psychosocial components to existing clinics.

Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration (EBUS-TBNA): A Practical Approach

Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration (EBUS-TBNA): A Practical Approach PDF Author: S.E. Monaco
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318023965
Category : Medical
Languages : en
Pages : 147

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Book Description
This high-yield reference book focuses on the clinical, technical, and pathological aspects of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). Its reviews cover all aspects of EBUS-TBNA, including the clinical perspective, technical aspects of the procedure, and cytomorphology of common and uncommon entities, as well as highlights diagnostic challenges. Each chapter features a multitude of full-color high-resolution images and includes key references to the current literature in the field. Additionally, reference tables and informative figures highlight the salient points. The book is unique in that it is written by experienced thoracic surgeons, pulmonary medicine physicians, and cytopathologists who use EBUS-TBNA in a large medical center. This publication is of interest to individuals learning and practicing cytopathology, in addition to clinicians practicing pulmonary/thoracic medicine or surgery. In short, it provides important pearls of wisdom to create a comprehensive reference for all physicians involved with EBUS-TBNA.