Dihydropyridines PDF Download
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Author: Wolf-Dieter Busse
Publisher: Springer Science & Business Media
ISBN: 3642957161
Category : Medical
Languages : en
Pages : 131
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Book Description
This volume reviews important milestones in the history of the development of 1,4-dihydropyridines starting in the late 1960s. The discovery led to theestablishment of Ca2+ antagonists as leading cardiovascular drugs throughoutthe world. This volume includes presentations of the results of some recent collaborative extramural studies by American investigators.
Author: Wolf-Dieter Busse
Publisher: Springer Science & Business Media
ISBN: 3642957161
Category : Medical
Languages : en
Pages : 131
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Book Description
This volume reviews important milestones in the history of the development of 1,4-dihydropyridines starting in the late 1960s. The discovery led to theestablishment of Ca2+ antagonists as leading cardiovascular drugs throughoutthe world. This volume includes presentations of the results of some recent collaborative extramural studies by American investigators.
Author: M.F. Rousseau
Publisher: Springer Science & Business Media
ISBN: 3642602207
Category : Medical
Languages : en
Pages : 83
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Book Description
Nisoldipine, a second generation of dihydropyridine derivative, exhibits high vascular and coronary selectivity. This monography focuses on the pharmacologic profile of Nisoldipine Coat-Core, a new galenic form, and its beneficial role in various clinical aspects of myocardial ischemia. The contributors are experts in the field of calcium antagonists.
Author: Lionel H. Opie
Publisher: Springer Science & Business Media
ISBN: 1461308631
Category : Medical
Languages : en
Pages : 315
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Book Description
Calcium antagonists are now regarded as the most important advance in cardiac drug therapy since the advent of beta-adrenergic blocking agents. Acting ba sically as vasodilators-though with many other com plex mechanisms especially in the case of the anti arrhythmic calcium antagonists, these agents have grown in importance to become among the therapeutic agents of first choice for angina pectoris and hyper tension. The major aim of the present book is to present the clinician with the information needed for the practical use of calcium antagonists. What do all the numerous and often conflicting trials say? Do these agents really work? If so, which agent and in what dose? How do the three front runners, verapamil, nifedipine and diltia zem compare in the efficacy and side-effects with each other? How do the new second generation agents, now entering the North American market, slot in and com pare with the three first-liners? When the gloss is taken away from the advertisements, what is really left? The strong clinical bias of the present book should be complimented by further reading of books slanted towards fundamentals. One of the most important and recent of these is that by Dr Winifred Nayler (Calcium Antagonists, Academic Press, 1988). That book should be basic for essential background knowledge in the area of calcium antagonists. The important basic contribu tions of Fleckenstein deserve emphasis.
Author: Jeffrey K. Aronson
Publisher: Elsevier
ISBN: 0080932894
Category : Medical
Languages : en
Pages : 841
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Book Description
Elsevier now offers a series of derivative works based on the acclaimed Meylers Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing physician or health care clinician. Each year, heart disease kills more people than cancer. Patients are treated by a variety of specialists and primary care practitioners, depending on the organ system involved. This volume enables practitioners to assess the adverse effects of the complete range of drugs used in cardiovascular medicine, including antihypertensive drugs, and drugs used in the treatment of heart failure, angina, angina pectoris, and cardiac arrhythmia and enable practitioners to prescribe preventative treatments with medications such as blood pressure reducers, aspirin, and cholesterol-lowering drugs, as well as drugs used for more aggressive therapy.The material is drawn from the 15th edition of the internationally renowned encyclopedia, Meyler’s Side Effects of Drugs, and the latest volumes in the companion series, Side Effects of Drugs Annuals. Drug names have usually been designated by their recommended or proposed International Non-proprietary Names (rINN or pINN); when those are not available, clinical names have been used. In some cases, brand names have been used.This volume is critical for any health professional involved in the administration of cardiovascular mediations. Surpasses the Physician’s Desk Reference © by including clinical case studies and independent expert analysis Complete index of drug names Most complete cross referencing of drug-drug interactions available Extensive references to primary and secondary literature Also includes information on adverse effects in pregnancy The book is divided into six sections: Drugs used to treat hypertension, heart failure and angina pectoris Diuretics – a general introduction to their adverse effects, followed by monographs on individual drugs Antidysrhythmic drugs - a general introduction to their adverse effects, followed by monographs on individual drugs Drugs that act on the cerebral and peripheral circulations Anticoagulants, thrombolytic agents, and anti-platelet drugs Cardiovascular adverse effects of non-cardiovascular drugs
Author: William H. Frishman
Publisher: Springer Science & Business Media
ISBN: 146156767X
Category : Medical
Languages : en
Pages : 350
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Book Description
The third edition of Current Cardiovascular Drugs is designed to provide an updated practical compendium of current knowledge regarding cardiovascular drug therapy in a concise, easily readable format. The book is organized into chapters by drug class, and details the pharmacologic characteristics of specific treatment entities. The clinical efficacy and limitations of the various drug therapies are discussed using supportive reference material from the most authoritative sources and published clinical trials.
Author: G.j. Blokdijk
Publisher: Createspace Independent Publishing Platform
ISBN: 9781984913623
Category :
Languages : en
Pages : 128
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Book Description
Who can I contact if I want to meet with a specialist for long-term Nisoldipine medication management on an ongoing basis? What are the adverse health effects from Nisoldipine prescription drugs? Are there less intrusive, harmless and effective solutions instead of Nisoldipine prescription drugs? How will I feel when I'm on Nisoldipine medications? Could I have afforded it without Nisoldipine prescription drug insurance? Always talk to your doctor about Nisoldipine, your condition and your treatment. But what exactly to ask your doctor to make sure you are both covering everything you need to know about Nisoldipine? 'Nisoldipine; The Ultimate Step-By-Step Guide' presents readers with a whole new set of 528 pivotal questions to discuss your situation with your healthcare provider, consider your options, and help you make decisions that are right for you. 'Nisoldipine; The Ultimate Step-By-Step Guide' poses questions that Nisoldipine medication users didn't even know they needed to ask. With lots of room to note down your doctor's answers and an extensive index, this book is a must-have for anyone who has, or is about to have, Nisoldipine prescription medication, and indispensable for healthcare providers who want to make sure they are able to answer every question.
Author: Basil S. Lewis
Publisher: Springer Science & Business Media
ISBN: 3642582311
Category : Medical
Languages : en
Pages : 713
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Book Description
Following remarkable advances in medical care. the past decade has witnessed a significant improvement in the survival of patients with many different forms of heart disease. In the majority ofcases. however. the advances have been pa lIiative and not curative. The resu It has been the prod uction of an ever-increasing population of patients with heart disease. many of whom suffer from myocardial dysfunction and latent or overt heart failure. Heart failure is now a major cause of morbidity and mortality in cardiac patients. This book aims to combine in a single volume data relating to both pathophysiological mechanisms and the clinical management of the patient with heart failure. It includes chapters dealing with molecular. biochemical. and pathophysiological aspects of heart failure. ven tricular function and its assessment. and the clinical aspects of heart failure in different cardiac disorders, including ischemic heart disease. valvular heart disease. and the cardiomyopathies. There are sections on pharmacotherapy. the role of arrhythmias, exercise physiology. and neurohumoral mechanisms. The book also deals with newer inter ventional techniques. newer surgical procedures and some current problems relating to cardiac assist devices and heart and heart-lungs transplantation.
Author: Paul R. Lichtlen
Publisher:
ISBN:
Category : Calcium
Languages : en
Pages : 168
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Book Description
Author: P. G. Hugenholtz
Publisher:
ISBN: 9783540183945
Category : Calcium
Languages : en
Pages : 0
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Book Description
Author: Zipeng Gong
Publisher: Frontiers Media SA
ISBN: 2832553192
Category : Science
Languages : en
Pages : 190
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Book Description
In the main frame of the above research topic, 16 contributions have been published including but not limited to the comparative pharmacokinetics between normal and disease status, the changes in the expression and function of drug-metabolizing enzymes and drug transporters in disease status and their related regulatory mechanisms, ADME/toxicity of drugs as well as their regulation, drug-drug interactions mediated by nuclear receptors, transporters and metabolic enzymes based on the methods and techniques of pharmacokinetics, transcriptomics, and metabolomics. However , the pharmacokinetic study is not only crucial in the development of new drugs, but also the study of pharmacokinetic-pharmacokinetic(PK-PD) model plays an important role in the process of new drug development. PK-PD model can reveal the internal relationship between drug concentration and effect, help to understand the dynamic characteristics of the drug action site in vivo and deduce the action site producing effect and drug concentration at the action site, which enables researchers to recognize the comprehensive characteristics of drug PK and PD processes in vivo. However, preclinical pharmacokinetic data are mainly derived from healthy animals, which is unreasonable. On the one hand, patients are the final consumers of drugs because drugs are mainly used to treat patients with diseases. On the other hand, whether the body is in a pathological state and the severity of the disease have different effects on the ADMEof drugs, which is closely related to whether the clinical drug is safe and effective. Therefore, studying the pharmacokinetics and PK-PD model in disease states is more meaningful and clinically relevant.
