New Strategies for Treatment of Sepsis

New Strategies for Treatment of Sepsis PDF Author: Antonio Mirijello
Publisher: Mdpi AG
ISBN: 9783036524832
Category : Medical
Languages : en
Pages : 146

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Book Description
This book represents a collection of paper from different specialists involved in the management of septic patients, aimed to disseminate the knowledge in the field of sepsis, particularly to non-intensivists physicians.

New Strategies for Treatment of Sepsis

New Strategies for Treatment of Sepsis PDF Author: Antonio Mirijello
Publisher: Mdpi AG
ISBN: 9783036524832
Category : Medical
Languages : en
Pages : 146

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Book Description
This book represents a collection of paper from different specialists involved in the management of septic patients, aimed to disseminate the knowledge in the field of sepsis, particularly to non-intensivists physicians.

Sepsis Management in Resource-limited Settings

Sepsis Management in Resource-limited Settings PDF Author: Arjen M. Dondorp
Publisher: Springer
ISBN: 3030031438
Category : Medical
Languages : en
Pages : 216

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Book Description
This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion.

Sepsis

Sepsis PDF Author: Jordi Rello
Publisher: Springer Science & Business Media
ISBN: 3540790012
Category : Medical
Languages : en
Pages : 147

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Book Description
Sepsis is an important public health problem around the world. Severe sepsis carries significant morbidity, mortality and high costs. The incidence of sepsis is increasing because of the aging population, the growing number of immunocompromised hosts, the increasing use of invasive procedures, and, to a lesser extent, antibiotic resistance among pathogens. Despite recent advances in the pathogenesis, diagnosis, and therapeutic approaches the mortality rate associated with this condition remains high. Therefore, the goal of Sepsis: New Strategies is to review novel targets to be considered in patients with severe sepsis and to assess new developments for patients with sepsis originating in the respiratory tract.

Sepsis

Sepsis PDF Author: Jordi Rello
Publisher: Springer
ISBN: 9783540871712
Category : Medical
Languages : en
Pages : 142

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Book Description
Sepsis is an important public health problem around the world. Severe sepsis carries significant morbidity, mortality and high costs. The incidence of sepsis is increasing because of the aging population, the growing number of immunocompromised hosts, the increasing use of invasive procedures, and, to a lesser extent, antibiotic resistance among pathogens. Despite recent advances in the pathogenesis, diagnosis, and therapeutic approaches the mortality rate associated with this condition remains high. Therefore, the goal of Sepsis: New Strategies is to review novel targets to be considered in patients with severe sepsis and to assess new developments for patients with sepsis originating in the respiratory tract.

Sepsis Management

Sepsis Management PDF Author: Jordi Rello
Publisher: Springer Science & Business Media
ISBN: 3642035191
Category : Medical
Languages : en
Pages : 243

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Book Description
This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent experts in the field from Europe and beyond offer new insights into risk stratification, severity assessment, and management of critically ill patients with sepsis. The principal focus is on recently developed concepts in infection management and in antibiotic use, bearing in mind that in these patients the pharmacokinetics of antibiotics are altered, affecting renal clearance and requiring dosage adjustments. The significance of the PIRO (predisposing factors, infection, response, organ dysfunction) model in the development of effective treatment strategies is emphasized. This book will be of interest and value to all who are involved in the treatment of, or research into, sepsis and MODS.

Sepsis

Sepsis PDF Author: Derek J. Chadwick
Publisher: John Wiley & Sons
ISBN: 0470059583
Category : Medical
Languages : en
Pages : 304

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Book Description
Sepsis: New Insights, New Therapies brings together contributions from an international group of experts in diverse fields to consider how the various pathways implicated in early and late sepsis interact, with a particular emphasis on novel concepts and potential new therapeutic approaches. Topics covered include adaptive immunity, inflammation, neuroendocrinology, bioenergetics and metabolism. Several chapters in the latter half of the book are particularly concerned with treatment strategies involving modulation of the neuroendocrine response. Addresses the frequent, but under-recognised condition of sepsis and discusses new ways to prevent and treat it Describes numerous pharmacological approaches to therapy for early and late sepsis Includes detailed discussion of the various physiological systems implicated in sepsis Presents an international perspective, featuring contributions from experts from laboratories worldwide involved in the study of sepsis Sepsis: New Insights, New Therapies is an invaluable resource for all critical care physicians and researchers. It is also informative reading for immunologists, endocrinologists, neuroendocrinologists, physiologists, and pharmacologists.

Novel Therapeutic Strategies in the Treatment of Sepsis

Novel Therapeutic Strategies in the Treatment of Sepsis PDF Author: David Morrison
Publisher: CRC Press
ISBN: 9780824796617
Category : Medical
Languages : en
Pages : 392

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Book Description
This up-to-the-minute, single-source reference examines the latest research efforts and preclinical approaches in the treatment of sepsis-discussing emerging ideas on mechanisms to combat septic shock and offering novel methods for interrupting the System Inflammatory Response Syndrome (SIRS) that leads to sepsis.

Clinical Trials for the Treatment of Sepsis

Clinical Trials for the Treatment of Sepsis PDF Author: W.J. Sibbald
Publisher: Springer Science & Business Media
ISBN: 3642792243
Category : Medical
Languages : en
Pages : 427

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Book Description
The incidence of sepsis is increasing as new medical and surgical technologies are applied to an increasingly aging patient population. The treatment of sepsis emphasizes strategies to avoid multiple organ dysfunction, with particular attention to establishing source control, and then modifies the host's response to the excessive inflammatory response which characterizes sepsis. This book is a comprehensive review by internationally recognized experts of the epidemiology, monitoring and treatment of sepsis. Using an "evidence-based" approach, it comprises an extensive review of the literature on sepsis, provides up-to-date recommendations for monitoring and treating sepsis patients, and concludes with explicit recommendations for the design and monitoring of future clinical trials.

Handbook of Sepsis

Handbook of Sepsis PDF Author: W. Joost Wiersinga
Publisher: Springer
ISBN: 3319735063
Category : Medical
Languages : en
Pages : 264

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Book Description
This practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the intensive care unit. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented, and individual chapters focus on aspects such as fluid resuscitation, vasopressor therapy, response to multiorgan failure, antimicrobial therapy, and adjunctive immunotherapy. The closing section looks forward to the coming decade, discussing novel trial designs, sepsis in low- and middle-income countries, and emerging management approaches. The book is internatio nal in scope, with contributions from leading experts worldwide. It will be of value to residents and professionals/practitioners in the fields of infectious diseases and internal medicine, as well as to GPs and medical students.

Hemodynamic Monitoring

Hemodynamic Monitoring PDF Author: Michael R. Pinsky
Publisher: Springer
ISBN: 3319692690
Category : Medical
Languages : en
Pages : 476

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Book Description
This book, part of the European Society of Intensive Care Medicine textbook series, teaches readers how to use hemodynamic monitoring, an essential skill for today’s intensivists. It offers a valuable guide for beginners, as well as for experienced intensivists who want to hone their skills, helping both groups detect an inadequacy of perfusion and make the right choices to achieve the main goal of hemodynamic monitoring in the critically ill, i.e., to correctly assess the cardiovascular system and its response to tissue oxygen demands. The book is divided into distinguished sections: from physiology to pathophysiology; clinical assessment and measurements; and clinical practice achievements including techniques, the basic goals in clinical practice as well as the more appropriate hemodynamic therapy to be applied in different conditions. All chapters use a learning-oriented style, with practical examples, key points and take home messages, helping readers quickly absorb the content and, at the same time, apply what they have learned in the clinical setting. The European Society of Intensive Care Medicine has developed the Lessons from the ICU series with the vision of providing focused and state-of-the-art overviews of central topics in Intensive Care and optimal resources for clinicians working in Intensive Care.