Neurotrophic Factors

Neurotrophic Factors PDF Author: Sandra E. Loughlin
Publisher: Elsevier
ISBN: 0080571328
Category : Science
Languages : en
Pages : 632

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Book Description
This volume clearly synthesizes current information on defined neurotrophic factors, emphasizing their localization and molecular/cellular function in the central nervous system. Brain development and aging, neurodegenerative disorders, plasticity, and memory all are closely examined within the context of this rapidly expanding field. Researchers in neurobiology, cell biology, and molecular biology will find Neurotrophic Factors an invaluable reference for their research libraries. - Offers the most up-do-date synthesis of concepts on neurotrophic factors in the nervous system - Integrates molecular, cellular, and neuroanatomical concepts of neurotrophic factor function - Includes special chapters on primary, secondary, and tertiary messenger systems - Examines brain development, differentiation, neurodegenerative disorders, and adult plasticity

Life and Death in the Nervous System

Life and Death in the Nervous System PDF Author: C. F. Ibanez
Publisher: Elsevier Health Sciences
ISBN: 1483287955
Category : Medical
Languages : en
Pages : 499

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Book Description
Life and Death in the Nervous System

Neurotrophic Factors

Neurotrophic Factors PDF Author: Sandra E. Loughlin
Publisher: Elsevier
ISBN: 0080571328
Category : Science
Languages : en
Pages : 632

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Book Description
This volume clearly synthesizes current information on defined neurotrophic factors, emphasizing their localization and molecular/cellular function in the central nervous system. Brain development and aging, neurodegenerative disorders, plasticity, and memory all are closely examined within the context of this rapidly expanding field. Researchers in neurobiology, cell biology, and molecular biology will find Neurotrophic Factors an invaluable reference for their research libraries. - Offers the most up-do-date synthesis of concepts on neurotrophic factors in the nervous system - Integrates molecular, cellular, and neuroanatomical concepts of neurotrophic factor function - Includes special chapters on primary, secondary, and tertiary messenger systems - Examines brain development, differentiation, neurodegenerative disorders, and adult plasticity

Basic Neurochemistry

Basic Neurochemistry PDF Author: George J. Siegel
Publisher: Lippincott Raven
ISBN:
Category : Medical
Languages : en
Pages : 1216

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Book Description
Illustrations by Lorie M. Gavulic, MFA Sponsored by the American Society for Neurochemistry.

Translational Pain Research

Translational Pain Research PDF Author: Lawrence Kruger
Publisher: CRC Press
ISBN: 1439812101
Category : Health & Fitness
Languages : en
Pages : 458

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Book Description
One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical

CNS Regeneration

CNS Regeneration PDF Author: Mark H. Tuszynski
Publisher: Academic Press
ISBN:
Category : Medical
Languages : en
Pages : 720

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Book Description
CNS Regeneration focuses on some of the leading current neurological disease models and methods for promoting central nervous system regeneration. Editors and authors are experts in the field, with experience in basic as well as applied neuroscience. In a comprehensive, logical manner, the book unites important basic science advances in neuroscience with novel medical strategies. The first comprehensive, authoritative volume on the topic of CNS regeneration Reviews current therapeutic approaches Editors and authors are experts in the field Appeals to those interested in basic science as well as those concerned with its medical application

Neurotrophic Factors

Neurotrophic Factors PDF Author: Patrick Aebischer
Publisher: Springer
ISBN:
Category : Medical
Languages : en
Pages : 352

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Book Description
With contributions of numerous experts.

Neurotrophic Factors

Neurotrophic Factors PDF Author: Stephen D Skaper
Publisher: Humana Press
ISBN: 9781617795374
Category : Medical
Languages : en
Pages : 421

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Book Description
Nervous system development evolves from the well-orchestrated processes of neural induction, cell proliferation, differentiation, cell migration, survival, and synapse formation. Among these environmental cues, neurotrophic factors are secreted proteins that promote neurite outgrowth, neuronal cell differentiation and survival both in vivo and in vitro. Nerve growth factor (NGF) is the founding and best characterized member of the neurotrophin family of neurotrophic polypeptides. Neurotrophic Factors: Methods and Protocols presents a selection of protocols and procedures which make use of cellular, tissue, and whole animal models which can be applied to the investigation of neurotrophic factors and other agents impacting on these systems. Chapters cover a wide-range of topics such as dealing with the culture of neurons and glia from the central and peripheral nervous systems, neuron-glia co-culture models, and cell-based assays for the evaluation of neuroprotective molecules, as well as assays which can be applied to the study of agents with neuroregenerative potential. Protocols describing viral- and nanoparticle-based delivery methods to neural cells are also presented, following by chapters dealing with organotypic slice culture protocols. Lastly, several chapters are dedicated to in vivo lesion models of relevance to nervous system pathology, which can be applied to the investigation of neurotrophic factors and peptides. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Neurotrophic Factors: Methods and Protocols seeks to serve both professionals and novices alike with its well-honed methodologies in an effort to further our knowledge of what has been described as the last frontier of science.

Neurotrophic Factors

Neurotrophic Factors PDF Author: Franz Hefti
Publisher:
ISBN: 9783642599217
Category :
Languages : en
Pages : 348

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Book Description
This volume provides the first comprehensive overview of a novel field of neuropharmacology. Neurotrophic factors are currently in clinical trials and there is a broad research effort which aims at alternative administration strategies and at replacing them with small molecule mimetics. The field represents a unique and novel approach to the treatment of neurodegenerative diseases.

The Neurobiological Basis of Suicide

The Neurobiological Basis of Suicide PDF Author: Yogesh Dwivedi
Publisher: CRC Press
ISBN: 143983881X
Category : Medical
Languages : en
Pages : 485

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Book Description
With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

Holland-Frei Cancer Medicine

Holland-Frei Cancer Medicine PDF Author: Robert C. Bast, Jr.
Publisher: John Wiley & Sons
ISBN: 111900084X
Category : Medical
Languages : en
Pages : 2004

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Book Description
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates