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Author: Bernhard Schaller
Publisher: Nova Publishers
ISBN: 9781604562279
Category : Medical
Languages : en
Pages : 204
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Book Description
This book focuses on advances in imaging and mapping strategies to study the brain's structure, function and the relationship between both, from the whole brain to the molecular and cellular tissue level in order to improve the understanding of normal and disease processes. Studies of intact living organisms may be at the human, animal, cellular or molecular level, which advance our understanding of biological events in living systems and how these events relate to normal and pathological processes. Imaging modalities include nuclear medicine techniques (SPECT and PET) and non-nuclear techniques such as MRI, MRS, CT, ultrasound, intravital microscopy, optical imaging, diffuse optical tomography, electromagnetic tomography and other methods which elucidate molecular and cellular mechanisms, accelerate the understanding of biology, test the efficacy of therapeutic interventions in intact living systems and assess the therapeutic outcomes.
Author: Bernhard Schaller
Publisher: Nova Publishers
ISBN: 9781604562279
Category : Medical
Languages : en
Pages : 204
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Book Description
This book focuses on advances in imaging and mapping strategies to study the brain's structure, function and the relationship between both, from the whole brain to the molecular and cellular tissue level in order to improve the understanding of normal and disease processes. Studies of intact living organisms may be at the human, animal, cellular or molecular level, which advance our understanding of biological events in living systems and how these events relate to normal and pathological processes. Imaging modalities include nuclear medicine techniques (SPECT and PET) and non-nuclear techniques such as MRI, MRS, CT, ultrasound, intravital microscopy, optical imaging, diffuse optical tomography, electromagnetic tomography and other methods which elucidate molecular and cellular mechanisms, accelerate the understanding of biology, test the efficacy of therapeutic interventions in intact living systems and assess the therapeutic outcomes.
Author: João O. Malva
Publisher: Frontiers Media SA
ISBN: 2889717259
Category : Science
Languages : en
Pages : 498
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Book Description
Author: Ronald A. Cohen
Publisher: Springer Science & Business Media
ISBN: 1441963731
Category : Psychology
Languages : en
Pages : 404
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Book Description
Rapid developments in brain neuroimaging methods have occurred over the past decade. These advances have revolutionized cognitive and behavioral neuroscience, and are likely to have major influence on clinical psychological, psychiatric, and neurological practice over the coming years. There are a number of excellent books that focus on specific neuroimaging methods, such as fMRI. Furthermore, cognitive and neuroscience texts have increasingly incorporated functional brain neuroimaging. Yet, there are few books to date that consider and review emerging research in the application of brain neuroimaging methods for the study and assessment of behavioral and cognitive disorders. This book provides a broad coverage of current research trends in the clinical application of brain neuroimaging methods in the context of behavioral medicine, neuropsychology, and related areas of medical psychology. It uniquely integrates current neuroimaging methods and studies with current behavioral medicine research, and presents knowledge derived from recent developments in the fields of functional and structural brain imaging. By integrating information from experimental behavioral medicine with clinical insights, this book will serve as a source book for neuropsychologists, psychologists, neurologists, psychiatrists, and other professionals in both clinical practice and academic context. This integration results in the reader having a greater understanding of how the brain controls behavior, the disturbances of behavior that may occur with different disorders, and what clinicians should consider when assessing or working with patients with behavioral problems.
Author: Floris G. Wouterlood
Publisher: Academic Press
ISBN: 0123858720
Category : Medical
Languages : en
Pages : 298
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Book Description
In the biomedical sciences, the confocal laser scanning microscope (CLSM) has become the instrument of choice for producing high-resolution images and 3D reconstruction, breaking the barriers of conventional optical microscopy. Wouterlood (anatomy, VU U. Medical Center, Amsterdam, the Netherlands) introduces the confocal principle which eliminates out-of-focus haze, its components, and relevant equations. International scientists explain the principles and related methods of stimulated emission depletion (SRED), single molecule localization, and coherent anti-Stokes Raman (CARS) microscopy; labeling approaches; preparation of samples for imaging; and applications of, and developments in, this new wave of imaging, e.g., visualization of neuronal networks, DNA, and myelin. The text includes color and b&w images, and referral to an online CLSM simulator. Academic Press is an imprint of Elsevier. Annotation ©2013 Book News, Inc., Portland, OR (booknews.com).
Author: Idan Segev
Publisher: Frontiers E-books
ISBN: 2889193608
Category : Art
Languages : en
Pages : 445
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Book Description
Could we understand, in biological terms, the unique and fantastic capabilities of the human brain to both create and enjoy art? In the past decade neuroscience has made a huge leap in developing experimental techniques as well as theoretical frameworks for studying emergent properties following the activity of large neuronal networks. These methods, including MEG, fMRI, sophisticated data analysis approaches and behavioral methods, are increasingly being used in many labs worldwide, with the goal to explore brain mechanisms corresponding to the artistic experience. The 37 articles composing this unique Frontiers Research Topic bring together experimental and theoretical research, linking state-of-the-art knowledge about the brain with the phenomena of Art. It covers a broad scope of topics, contributed by world-renowned experts in vision, audition, somato-sensation, movement, and cinema. Importantly, as we felt that a dialog among artists and scientists is essential and fruitful, we invited a few artists to contribute their insights, as well as their art. Joan Miró said that “art is the search for the alphabet of the mind.” This volume reflects the state of the art search to understand neurobiological alphabet of the Arts. We hope that the wide range of articles in this volume will be highly attractive to brain researchers, artists and the community at large.
Author: Alessandro Grecucci
Publisher: Frontiers Media SA
ISBN: 2889453162
Category :
Languages : en
Pages : 143
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Book Description
In the last twenty years, many attempts have been made to provide neurobiological models of autism. Functional, structural and connectivity analyses have highlighted reduced responses in key social areas, such as amygdala, medial prefrontal cortex, cingulate cortex, and superior temporal sulcus. However, these studies present discrepant results and some of them have been questioned for methodological limitations. The aim of this research topic is to present advanced neuroimaging methods able to capture the complexity of the neural deficits displayed in autism. This special issue presents new studies using structural and functional MRI, as well as magnetoencephalography, and novel protocols to analyze data (Analysis of Cluster Variability, Noise Reduction Strategies, Source-based Morphometry, Functional Connectivity Density, Restriction Spectrum Imaging and the others). We believe it is time to integrate data provided by different techniques and methodologies in order to have a better understanding of autism.
Author: Matt Carter
Publisher: Academic Press
ISBN: 0323915612
Category : Medical
Languages : en
Pages : 416
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Book Description
Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. - Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods - Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more - Clear, straightforward explanations of each technique for anyone new to the field - A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture - Detailed recommendations on where to find protocols and other resources for specific techniques - "Walk-through" boxes that guide readers through experiments step-by-step
Author: Cynthia H. Y. Fu
Publisher: CRC Press
ISBN: 9781841842295
Category : Medical
Languages : en
Pages : 288
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Book Description
New neuroimaging techniques are developing at a break neck pace-every academic journal contains glossy pictures of brain activity corresponding to a particular task emblazoned in glorious technicolor. Discoveries about brain function in psychiatric disorders have been made at an equally rapid rate. However, most books on the subject have been written from a technical point of view. An introductory, easy-to-read guide, Neuroimaging in Psychiatry provides an overview and the clinical relevance of the latest neuroimaging findings. With contributions from an international panel of experts, this book reviews current findings from neuroimaging in schizophrenia, obsessive-compulsive disorder, depression, eating disorders, psychopathy, aging, and drug addiction. Chapter authors explore innovative and imaginative uses of neuro imaging technology, implications for our understanding of these disorders, and their impact on clinical practice. The book gives you a general overview of the main techniques to help you successfully complete a neuroimaging project.
Author: George J. Augustine
Publisher: Frontiers Media SA
ISBN: 2889451755
Category :
Languages : en
Pages : 127
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Book Description
Development of new imaging technologies in recent years has transformed neuroscience in profound ways. Following on the heels of the revolution based on the Green Fluorescent Protein, refined genetically-encoded fluorescent reporters and genetic targeting strategies now enable optical recording of synaptic transmission in defined neuronal populations at speeds approaching the enviable temporal resolution of electrophysiology. Super-resolution light microscopy permits observation of synapses and their molecular machinery at sub-diffraction resolution. At the ultrastructural level, automated forms of electron microscopy, improvements in specimen fixation methods, and recent efforts to correlate data from light and electron micrographs now make the reconstruction of functional neural circuits a reality. Finally, the use of optogenetic actuators, such as channelrhodopsins, allows precise temporal and spatial manipulation of neuronal activity and is revealing profound insights into the organization of neural circuits and their roles in behavior. This research topic highlights recent advances in both light and electron microscopy, with a specific focus on approaches that combine innovations from several different fields to obtain novel information about synapse structure and function. We are confident that this collection of articles - three original research papers, six reviews, one methods paper and one perspective article - will enable neuroscientists to achieve the next generation of experiments aimed at cracking the neural code.
Author: José M Medina
Publisher: Frontiers Media SA
ISBN: 288919566X
Category : Neuropsychology
Languages : en
Pages : 170
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Book Description
Mental chronometry encompasses all aspects of time processing in the nervous system and constitutes a standard tool in many disciplines including theoretical and experimental psychology and human neuroscience. Mental chronometry has represented a fundamental approach to elucidate the time course of many cognitive phenomena and their underlying neural circuits over more than a century. Nowadays, mental chronometry continues evolving and expanding our knowledge, and our understanding of the temporal organization of the brain in combination with different neuroscience techniques and advanced methods in mathematical analysis. In research on mental chronometry, human reaction/responses times play a central role. Together with reaction times, other topics in mental chronometry include vocal, manual and saccadic latencies, subjective time, psychological time, interval timing, time perception, internal clock, time production, time representation, time discrimination, time illusion, temporal summation, temporal integration, temporal judgment, redundant signals effect, perceptual, decision and motor time, etc. The aim of this research topic is to provide an overview of the state of the art in this field?its relevance, recent findings, current challenges, perspectives and future directions. Thus, as a result, a collection of 14 original research and opinion papers from different experts have been gathered together in a single volume. We hope this research topic will provide a useful framework and an up-to-date set of papers for further discussion on mental chronometry within the human brain. We are grateful to all the referees for their valuable support, effort, and time during the creation of the research topic. Granada, April 2015 José M Medina Willy Wong José A Díaz Hans Colonius
