NINDS at 50

NINDS at 50 PDF Author: Lewis P. Rowland
Publisher:
ISBN:
Category :
Languages : en
Pages : 348

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NINDS at 50

NINDS at 50 PDF Author: Lewis P. Rowland
Publisher:
ISBN:
Category :
Languages : en
Pages : 348

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Book Description


Neurological, Psychiatric, and Developmental Disorders

Neurological, Psychiatric, and Developmental Disorders PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309170931
Category : Medical
Languages : en
Pages : 458

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Book Description
Brain disordersâ€"neurological, psychiatric, and developmentalâ€"now affect at least 250 million people in the developing world, and this number is expected to rise as life expectancy increases. Yet public and private health systems in developing countries have paid relatively little attention to brain disorders. The negative attitudes, prejudice, and stigma that often surround many of these disorders have contributed to this neglect. Lacking proper diagnosis and treatment, millions of individual lives are lost to disability and death. Such conditions exact both personal and economic costs on families, communities, and nations. The report describes the causes and risk factors associated with brain disorders. It focuses on six representative brain disorders that are prevalent in developing countries: developmental disabilities, epilepsy, schizophrenia, bipolar disorder, depression, and stroke. The report makes detailed recommendations of ways to reduce the toll exacted by these six disorders. In broader strokes, the report also proposes six major strategies toward reducing the overall burden of brain disorders in the developing world.

Functional Neurologic Disorders

Functional Neurologic Disorders PDF Author:
Publisher: Academic Press
ISBN: 0128018496
Category : Medical
Languages : en
Pages : 684

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Book Description
Functional Neurologic Disorders, the latest volume in the Handbook of Clinical Neurology series, summarizes state-of-the-art research findings and clinical practice on this class of disorders at the interface between neurology and psychiatry. This 51-chapter volume offers an historical introduction, chapters on epidemiology and pathophysiolology, a large section on the clinical features of different type of functional neurologic symptoms and disorders (including functional movement disorders, non-epileptic seizures, dizziness, vision, hearing, speech and cognitive symptoms), and then concluding with approaches to therapy. This group of internationally acclaimed experts in neurology, psychiatry, and neuroscience represent a broad spectrum of areas of expertise, chosen for their ability to write clearly and concisely with an eye toward a clinical audience. This HCN volume sets a new landmark standard for a comprehensive, multi-authored work dealing with functional neurologic disorders (also described as psychogenic, dissociative or conversion disorders). - Offers a comprehensive interdisciplinary approach for the care of patients with functional disorders seen in neurologic practice, leading to more efficient prevention, management, and treatment - Provides a synthesis of research efforts incorporating clinical, brain imaging and neurophysiological studies - Fills an existing gap between traditional neurology and traditional psychiatry - Contents include coverage of history, epidemiology, clinical presentations, and therapy - Edited work with chapters authored by leaders in the field, the broadest, most expert coverage available

Improving the Utility and Translation of Animal Models for Nervous System Disorders

Improving the Utility and Translation of Animal Models for Nervous System Disorders PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309266335
Category : Medical
Languages : en
Pages : 111

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Book Description
Nervous system diseases and disorders are highly prevalent and substantially contribute to the overall disease burden. Despite significant information provided by the use of animal models in the understanding of the biology of nervous system disorders and the development of therapeutics; limitations have also been identified. Treatment options that are high in efficacy and low in side effects are still lacking for many diseases and, in some cases are nonexistent. A particular problem in drug development is the high rate of attrition in Phase II and III clinical trials. Why do many therapeutics show promise in preclinical animal models but then fail to elicit predicted effects when tested in humans? On March 28 and 29, 2012, the Institute of Medicine Forum on Neuroscience and Nervous System Disorders convened the workshop "Improving Translation of Animal Models for Nervous System Disorders" to discuss potential opportunities for maximizing the translation of new therapies from animal models to clinical practice. The primary focus of the workshop was to examine mechanisms for increasing the efficiency of translational neuroscience research through discussions about how and when to use animal models most effectively and then best approaches for the interpretation of the data collected. Specifically, the workshop objectives were to: discuss key issues that contribute to poor translation of animal models in nervous system disorders, examine case studies that highlight successes and failures in the development and application of animal models, consider strategies to increase the scientific rigor of preclinical efficacy testing, explore the benefits and challenges to developing standardized animal and behavioral models. Improving the Utility and Translation of Animal Models for Nervous System Disorders: Workshop Summary also identifies methods to facilitate development of corresponding animal and clinical endpoints, indentifies methods that would maximize bidirectional translation between basic and clinical research and determines the next steps that will be critical for improvement of the development and testing of animal models of disorders of the nervous system.

Pain

Pain PDF Author:
Publisher:
ISBN:
Category : Chronically ill
Languages : en
Pages : 58

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Epilepsy Across the Spectrum

Epilepsy Across the Spectrum PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309259533
Category : Medical
Languages : en
Pages : 568

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Book Description
Although epilepsy is one of the nation's most common neurological disorders, public understanding of it is limited. Many people do not know the causes of epilepsy or what they should do if they see someone having a seizure. Epilepsy is a complex spectrum of disorders that affects an estimated 2.2 million Americans in a variety of ways, and is characterized by unpredictable seizures that differ in type, cause, and severity. Yet living with epilepsy is about much more than just seizures; the disorder is often defined in practical terms, such as challenges in school, uncertainties about social situations and employment, limitations on driving, and questions about independent living. The Institute of Medicine was asked to examine the public health dimensions of the epilepsies, focusing on public health surveillance and data collection; population and public health research; health policy, health care, and human services; and education for people with the disorder and their families, health care providers, and the public. In Epilepsy Across the Spectrum, the IOM makes recommendations ranging from the expansion of collaborative epilepsy surveillance efforts, to the coordination of public awareness efforts, to the engagement of people with epilepsy and their families in education, dissemination, and advocacy for improved care and services. Taking action across multiple dimensions will improve the lives of people with epilepsy and their families. The realistic, feasible, and action-oriented recommendations in this report can help enable short- and long-term improvements for people with epilepsy. For all epilepsy organizations and advocates, local, state, and federal agencies, researchers, health care professionals, people with epilepsy, as well as the public, Epilepsy Across the Spectrum is an essential resource.

Neurological Research Supported by the National Institute of Neurological Diseases and Stroke

Neurological Research Supported by the National Institute of Neurological Diseases and Stroke PDF Author: National Institute of Neurological Diseases and Stroke
Publisher:
ISBN:
Category : Neurology
Languages : en
Pages : 264

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Book Description


Imaging of Traumatic Brain Injury

Imaging of Traumatic Brain Injury PDF Author: Yoshimi Anzai
Publisher: Thieme
ISBN: 1604067292
Category : Medical
Languages : en
Pages : 519

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Book Description
An image-rich text on neuroimaging of trauma patients Imaging of Traumatic Brain Injury is a radiological reference that covers all aspects of neurotrauma imaging and provides a clinical overview of traumatic brain injury (TBI). It describes the imaging features of acute head trauma, the pathophysiology of TBI, and the application of advanced imaging technology to brain-injured patients. Key Features: Covers acute as well as chronic traumatic brain injury Written in an easily accessible format, with pearls and summary boxes at the end of each chapter Includes state-of-the-art imaging techniques, including the multiplanar format, the utility of multiplanar reformats, perfusion imaging, susceptibility weighted imaging, and advanced MRI techniques Contains over 250 high-quality images This book will serve as a practical reference for practicing radiologists as well as radiology residents and fellows, neurosurgeons, trauma surgeons, and emergency physicians.

Neurological Research Supported by the National Institute of Neurological Diseases and Stroke

Neurological Research Supported by the National Institute of Neurological Diseases and Stroke PDF Author: National Institutes of Health (U.S.)
Publisher:
ISBN:
Category : Neurology
Languages : en
Pages : 264

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Book Description


Concussion Care Manual

Concussion Care Manual PDF Author: David L. Brody MD
Publisher: Oxford University Press
ISBN: 0190054816
Category : Medical
Languages : en
Pages : 257

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Book Description
It is hard to find a medical condition that has as much media attention as concussion. With growing interest in concussion care by the NFL, NHL, NBA, and many other sports organizations, the military, and by regular patients, the number of concussion care providers has rapidly increased. Concussion Care Manual, Second Edition is the perfect step-by-step concussion management guide for clinicians, coaches, and even parents of athletic children. This pocket-sized volume discusses how to manage a variety of complexities associated with concussions including proper diagnosis, management strategies, headaches, anxiety and depression, PTSD, dizziness, fatigue, and changes to mood, balance, personality, and sleep. This book also covers the essential elements on how to set up and run a concussion clinic, focusing on the administrative need-to-know. A much-needed list of references, scales, and resources are provided at the end of the book for further investigation. New to the Second Edition… -Fully revised based on the most up-to-date research in the field across disciplines - Evidence-based, this new edition summarizes what works and what doesn't from recent clinical trials and real world concussion care experience -Provides step by step guidance on how to provide appropriate active management when treating concussion