Molecular Analysis of B Lymphocyte Development and Activation PDF Download

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Molecular Analysis of B Lymphocyte Development and Activation

Molecular Analysis of B Lymphocyte Development and Activation PDF Author: Harinder Singh
Publisher: Springer Science & Business Media
ISBN: 3540263632
Category : Medical
Languages : en
Pages : 261

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Book Description
The B lymphocyte lineage represents an important paradigm for exploring the molecular mechanisms underlying cell fate specification, differentiation and cellular activation. In the past five years, major advances have been achieved in our understanding of the transcriptional control of early B cell development and terminal plasma cell differentiation. In addition new insights became available for the processes of B cell activation, class switch recombination and somatic hypermutation. Many of the new findings and their implications for a molecular understanding of B cell biology in particular and cell differentiation in general are covered in this volume.