Microenvironmental Aspects of Immunity PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Microenvironmental Aspects of Immunity PDF full book. Access full book title Microenvironmental Aspects of Immunity by B. Jankovic. Download full books in PDF and EPUB format.
Author: B. Jankovic
Publisher: Springer Science & Business Media
ISBN: 1461590175
Category : Medical
Languages : en
Pages : 710
Get Book
Book Description
Author: B. Jankovic
Publisher: Springer Science & Business Media
ISBN: 1461590175
Category : Medical
Languages : en
Pages : 710
Get Book
Book Description
Author:
Publisher:
ISBN:
Category : Immunity
Languages : en
Pages :
Get Book
Book Description
Author: Anne Le
Publisher: Springer
ISBN: 331977736X
Category : Medical
Languages : en
Pages : 186
Get Book
Book Description
Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
Author: Branislav D. Jankovic
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Get Book
Book Description
Author: Petranel T. Ferrao
Publisher: Frontiers Media SA
ISBN: 288963115X
Category :
Languages : en
Pages : 186
Get Book
Book Description
Cancer cells can change and adapt, especially within the host environment; a phenomenon known as cancer plasticity. Several factors, including the immune system can influence, and be influenced by, cancer plasticity which in turn can impact upon patient responses to treatment. As such, we currently face several challenges for implementing combination therapies as effective cancer treatment strategies. We have compiled a topic with a number of articles that emphasize the various aspects of cancer plasticity, describing in particular the important role of the tumor microenvironment. As we embark on a new era of precision medicine with multi-modal therapies for improving patient outcomes, this topic highlights some relevant points for consideration that are pertinent to the incorporation and effective use of new treatments as part of cancer treatment regimens, including immune-modulating drugs.
Author: Valérie Dutoit
Publisher: Frontiers Media SA
ISBN: 2889741915
Category : Medical
Languages : en
Pages : 212
Get Book
Book Description
Author: Yewei Zhang
Publisher: Frontiers Media SA
ISBN: 2832547699
Category : Medical
Languages : en
Pages : 246
Get Book
Book Description
A common feature of cancer metabolism is the ability to obtain essential nutrients from a nutrient-poor environment and use them to maintain viability as well as generate new biomass. Alterations in intracellular and extracellular metabolites can be accompanied by tumor-associated metabolic reprogramming with profound effects on gene expression, cell differentiation, and tumor microenvironment. In these cases, the metabolic microenvironment of the tumor itself can present an immunosuppressive environment that needs to be overcome. Specifically, it will help maximize the efficacy of cancer therapies by identifying targets that suppress or alter cancer metabolism to improve the tumor microenvironment nutrient availability or that modulate immune metabolism to bolster inflammation.
Author: Eitan Yefenof
Publisher: Springer Science & Business Media
ISBN: 140206750X
Category : Medical
Languages : en
Pages : 215
Get Book
Book Description
Traditionally, the interplay between cancer cells and host immunity has been studied systemically. Recent studies, however, indicate that the tumor microenvironment is unique in providing both supportive and inhibitory factors that determine the fate of the tumor and its host. This volume compiles reviews on innate and adaptive immune responses at the tumor microenvironment with emphasis on positive and negative outcomes that affect the progression of the disease.
Author: Pawel Kalinski
Publisher: Springer
ISBN: 331967577X
Category : Medical
Languages : en
Pages : 271
Get Book
Book Description
The tumor microenvironment has become a very important and hot topic in cancer research within the past few years. The tumor microenvironment is defined as the normal cells, molecules, and blood vessels that surround and feed a tumor cell. As many scientists have realized, studying the tumor microenvironment has become critical to moving the field forward, since there are many players in a tumor’s localized and surrounding area, which can significantly change cancer cell behavior. There is a dual relationship wherein the tumor can change its microenvironment and the microenvironment can affect how a tumor grows and spreads. Tumor Microenvironment in Cancer Progression and Cancer Therapy aims to shed light on the mechanisms, factors, and mediators that are involved in the cancer cell environment. Recent studies have demonstrated that in addition to promoting tumor progression and protecting tumor cells from the spontaneous immune-mediated rejection and different forms of cancer therapeutics, tumor microenvironment can also be a target and mediator of both standard and newly-emerging forms of cancer therapeutics. Thus, the dual role of the tumor microenvironment is the integral focus of the volume. The volume highlights the bi-directional interactions between tumor cells and non-malignant tumor component during tumor progression and treatment. It also focuses on the three groups of the reactive tumor component: stromal cells, blood vessels and the infiltrating immune cells. These three groups are discussed under the lens of their role in promoting tumor growth, shielding the tumor from rejection and from standard forms of cancer therapies. They are emerging as targets and mediators of standard and new forms of potential therapy.
Author: Roi Gazit
Publisher: Frontiers Media SA
ISBN: 2832530362
Category : Medical
Languages : en
Pages : 190
Get Book
Book Description
