Methods of Therapeutic Drug Monitoring Including Pharmacogenetics PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Methods of Therapeutic Drug Monitoring Including Pharmacogenetics PDF full book. Access full book title Methods of Therapeutic Drug Monitoring Including Pharmacogenetics by Georg Hempel. Download full books in PDF and EPUB format.
Author: Georg Hempel
Publisher: Elsevier
ISBN: 0444640673
Category : Science
Languages : en
Pages : 382
Get Book Here
Book Description
Methods of Therapeutic Drug Monitoring Including Pharmacogenetics, Second Edition, Volume Seven in the Handbook of Analytical Separations series, covers all aspects of drug monitoring, including laboratory work, pharmacokinetic analysis and clinical aspects, thus enabling readers from different fields to understand the whole process of therapeutic drug monitoring and how to avoid common pitfalls. The book contains analytical techniques for the quantification of drugs, along with pharmacogenetic and pharmacogenomic methods. Also included are updates on sample preparation, including dried blood spot technology and microextraction methods. In addition, the book includes new drugs, such as tyrosine kinase inhibitors and the monitoring of immunosuppressant drugs. - Presents a unique, interdisciplinary approach that appeals to a wide range of users - Written by authors from international labs, providing a global perspective that can be applied in various regulatory environments - Features additional therapeutic drugs to reflect the rising number of immunocompromised patients - Includes a new mass spectroscopic methods chapter to capture the frequent use in TDM and the improved availability of LC-MS across laboratories
Author: Georg Hempel
Publisher: Elsevier
ISBN: 0444640673
Category : Science
Languages : en
Pages : 382
Get Book Here
Book Description
Methods of Therapeutic Drug Monitoring Including Pharmacogenetics, Second Edition, Volume Seven in the Handbook of Analytical Separations series, covers all aspects of drug monitoring, including laboratory work, pharmacokinetic analysis and clinical aspects, thus enabling readers from different fields to understand the whole process of therapeutic drug monitoring and how to avoid common pitfalls. The book contains analytical techniques for the quantification of drugs, along with pharmacogenetic and pharmacogenomic methods. Also included are updates on sample preparation, including dried blood spot technology and microextraction methods. In addition, the book includes new drugs, such as tyrosine kinase inhibitors and the monitoring of immunosuppressant drugs. - Presents a unique, interdisciplinary approach that appeals to a wide range of users - Written by authors from international labs, providing a global perspective that can be applied in various regulatory environments - Features additional therapeutic drugs to reflect the rising number of immunocompromised patients - Includes a new mass spectroscopic methods chapter to capture the frequent use in TDM and the improved availability of LC-MS across laboratories
Author: Amitava Dasgupta
Publisher: Academic Press
ISBN: 0128158506
Category : Science
Languages : en
Pages : 384
Get Book Here
Book Description
Therapeutic Drug Monitoring Data: A Concise Guide, Fourth Edition serves as a ready resource of information on commonly monitored drugs that will help readers make decisions relating to the monitoring and interpretation of results. It is an easy-to-read source of information on intended use, pharmacokinetics, therapeutic range, and toxic concentrations, as well as bioavailability, disposition, metabolism and the excretion of commonly monitored therapeutic drugs. This fully updated fourth edition includes sections on new anticonvulsants, anti-depressant and anti-HIV drugs, new drugs for advanced cancer treatment, and thoroughly updated chapters that address new pitfalls and problems in the lab. - Serves as a ready resource of information for commonly monitored drugs - Presents a useful, quick guide for those making decisions related to monitoring and interpretation of results - Provides concise, easily digestible content for clinical laboratory scientists, toxicologists and clinicians
Author: Amitava Dasgupta
Publisher: Springer Science & Business Media
ISBN: 1588297802
Category : Medical
Languages : en
Pages : 441
Get Book Here
Book Description
Written in a handbook style with specific methods and tips on eliminating false positive and false negative results, this book is a practical guide to the detailed mechanisms of such occurrences.
Author: Kewal K. Jain
Publisher: Humana Press
ISBN: 1493925539
Category : Medical
Languages : en
Pages : 762
Get Book Here
Book Description
Advances in the technology used in personalized medicine and increased applications for clinical use have created a need for this expansion and revision of Kewal K. Jain’s Textbook of Personalized Medicine. As the first definitive work on this topic, this book reviews the fundamentals and development of personalized medicine and subsequent adoptions of the concepts by the biopharmaceutical industry and the medical profession. It also discusses examples of applications in key therapeutic areas, as well as ethical and regulatory issues, providing a concise and comprehensive source of reference for those involved in healthcare management, planning and politics. Algorithms are included as a guide to those involved in the management of important diseases where decision-making is involved due to the multiple choices available. Textbook of Personalized Medicine, Second Edition will serve as a convenient source of information for physicians, scientists, decision makers in the biopharmaceutical and healthcare industries and interested members of the public.
Author: Weimin Cai
Publisher: Springer
ISBN: 9789811538971
Category : Medical
Languages : en
Pages : 289
Get Book Here
Book Description
This book provides an introduction to the principles of pharmacogenomics and precision medicine, followed by the pharmacogenomics aspects of major therapeutic areas such as cardiovascular disease, cancer, organ transplantation, psychiatry, infection, antithrombotic drugs. It also includes genotyping technology and therapeutic drug monitoring in Pharmacogenomics; ethical, Legal and Regulatory Issues; cost-effectiveness of pharmacogenetics-guided treatment; application of pharmacogenomics in drug discovery and development and clinical Implementation of Pharmacogenomics for Personalized Precision Medicine. The contributors of Pharmacogenomics in Precision Medicine come from a team of experts, including professors from academic institutions and practitioner from hospital. It will give an in-depth overview of the current state of pharmacogenomics in drug therapy for all health care professionals and graduate students in the era of precision medicine.
Author: David F. Kisor
Publisher: Jones & Bartlett Publishers
ISBN: 1449633943
Category : Medical
Languages : en
Pages : 225
Get Book Here
Book Description
Pharmacogenetics, Kinetics, and Dynamics for Personalized Medicine provides a primer to understand pharmacogenetics (the study of genetic factors that influence how a drug works) in the applied context of pharmacokinetics (how the body handles a drug) and pharmacodynamics (the effects of a drug on the body). This valuable foundation illuminates how these principles and scientific advances can create optimal individual patient care, that is, "personalized medicine." Through specific drug examples, this resource explores how the genetic constitution of an individual may lead to the need for an altered dose or in some cases alternative drug therapy. Real-world cases highlight the specific relationships between genetics, drug action, and the body's response as well as adverse drug reactions, altered metabolism, and drug efficacy. Ethical issues concerning pharmacogenomics and study design are also discussed in this concise overview.
Author: Edward C.C. Wong
Publisher: Academic Press
ISBN: 0128179635
Category : Science
Languages : en
Pages : 1172
Get Book Here
Book Description
Biochemical and Molecular Basis of Pediatric Disease, Fifth Edition has been a well-respected reference in the field for decades. This revision continues the strong focus on understanding the pathogenesis of pediatric disease, emphasizing not only the important role of the clinical laboratory in defining parameters that change with the disease process, but also the molecular basis of many pediatric diseases. - Provides a fully-updated resource with more color illustrations - Focuses on the biochemical and molecular basis of disease as well as the analytical techniques - Defines important differences in the pathophysiology of diseases, comparing childhood with adult
Author: William Clarke
Publisher: Elsevier
ISBN: 9780128020258
Category : Medical
Languages : en
Pages : 0
Get Book Here
Book Description
Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions and Pharmacogenomics focuses on critical issues in therapeutic drug monitoring including special requirements of therapeutic drug monitoring important to special populations (infants and children, pregnant women, elderly patients, and obese patients). The book also covers issues of free drug monitoring and common interferences in using immunoassays for therapeutic drug monitoring. This book is essential reading for any clinician, fellow, or trainee who wants to gain greater insight into the process of therapeutic drug monitoring for individual dosage adjustment and avoiding drug toxicity for certain drugs within a narrow therapeutic window. The book is written specifically for busy clinicians, fellows, and trainees who order therapeutic drug monitoring and need to get more familiar with testing methodologies, issues of interferences, and interpretation of results in certain patient populations.
Author: Roger W Jelliffe
Publisher: Academic Press
ISBN: 0128033495
Category : Computers
Languages : en
Pages : 435
Get Book Here
Book Description
Individualized Drug Therapy for Patients: Basic Foundations, Relevant Software and Clinical Applications focuses on quantitative approaches that maximize the precision with which dosage regimens of potentially toxic drugs can hit a desired therapeutic goal. This book highlights the best methods that enable individualized drug therapy and provides specific examples on how to incorporate these approaches using software that has been developed for this purpose. The book discusses where individualized therapy is currently and offers insights to the future. Edited by Roger Jelliffe, MD and Michael Neely, MD, renowned authorities in individualized drug therapy, and with chapters written by international experts, this book provides clinical pharmacologists, pharmacists, and physicians with a valuable and practical resource that takes drug therapy away from a memorized ritual to a thoughtful quantitative process aimed at optimizing therapy for each individual patient. - 2018 PROSE Awards - Honorable Mention, Clinical Medicine: Association of American Publishers - Uses pharmacokinetic approaches as the tools with which therapy is individualized - Provides examples using specific software that illustrate how best to apply these approaches and to make sense of the more sophisticated mathematical foundations upon which this book is based - Incorporates clinical cases throughout to illustrate the real-world benefits of using these approaches - Focuses on quantitative approaches that maximize the precision with which dosage regimens of potentially toxic drugs can hit a desired therapeutic goal
Author: William E. Evans
Publisher: Applied Therapeutics, Incorporated
ISBN:
Category : Medical
Languages : en
Pages : 1236
Get Book Here
Book Description
The Third Edition of Applied Pharmacokinetics remains the gold standard by which all other clinical pharmacokinetics texts are measured. Written by leading pharmacokinetics researchers and practitioners, this book is the most advanced kinetics reference available. All chapters have been extensively updated or completely rewritten for this edition, and six new chapters have been added on pharmacodynamics, pharmacogenetics, pharmacokinetic considerations in the obese, dietary influences on drug disposition, zidovudine, and corticosteroids. Each chapter is tightly focused on the most important concepts and issues. Chapters on specific drugs are organized in a consistent format for quick, easy information retrieval. Major subheadings include Clinical Pharmacokinetics, Pharmacodynamics, Clinical Application of Pharmacokinetic Data, Analytical Methods, and Prospectus.
