Magnesium in the Central Nervous System

Magnesium in the Central Nervous System PDF Author: Robert Vink
Publisher: University of Adelaide Press
ISBN: 0987073052
Category : Medical
Languages : en
Pages : 354

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Book Description
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Magnesium in the Central Nervous System

Magnesium in the Central Nervous System PDF Author: Robert Vink
Publisher: University of Adelaide Press
ISBN: 0987073052
Category : Medical
Languages : en
Pages : 354

Get Book Here

Book Description
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Interrelations between Essential Metal Ions and Human Diseases

Interrelations between Essential Metal Ions and Human Diseases PDF Author: Astrid Sigel
Publisher: Springer
ISBN: 9789402402711
Category : Science
Languages : en
Pages : 0

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Book Description
MILS-13 provides an up-to-date review on the relationships between essential metals and human diseases, covering 13 metals and 3 metalloids: The bulk metals sodium, potassium, magnesium, and calcium, plus the trace elements manganese, iron, cobalt, copper, zinc, molybdenum, and selenium, all of which are essential for life. Also covered are chromium, vanadium, nickel, silicon, and arsenic, which have been proposed as being essential for humans in the 2nd half of the last century. However, if at all, they are needed only in ultra-trace amounts, and because of their prevalence in the environment, it has been difficult to prove whether or not they are required. In any case, all these elements are toxic in higher concentrations and therefore, transport and cellular concentrations of at least the essential ones, are tightly controlled; hence, their homeostasis and role for life, including deficiency or overload, and their links to illnesses, including cancer and neurological disorders, are thoroughly discussed. Indeed, it is an old wisdom that metals are indispensable for life. Therefore, Volume 13 provides in an authoritative and timely manner in 16 stimulating chapters, written by 29 internationally recognized experts from 7 nations, and supported by more than 2750 references, and over 20 tables and 80 illustrations, many in color, a most up-to-date view on the vibrant research area of the Interrelations between Essential Metal Ions and Human Diseases.

Magnesium Deficiency in the Pathogenesis of Disease

Magnesium Deficiency in the Pathogenesis of Disease PDF Author: Mildred S. Seelig
Publisher: Springer Science & Business Media
ISBN: 1468491083
Category : Medical
Languages : en
Pages : 495

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Book Description
There is a large and rapidly growing body of literature on the importance of mag nesium in biochemical and physiological processes. There is also much evidence that magnesium deficiency, alone and in combination with agents that interfere with its utilization, is associated with functional and structural abnormalities of mem branes, cells, organs, and systems. The manifestations of the changes caused by magnesium deficiency depend upon its extent and duration and on variable factors. Among the conditions that increase the risk of magnesium deficiency are (1) meta bolic factors that affect the absorption, distribution, and excretion of this mineral; (2) disease and therapy; (3) physiologic states that increase requirements for nutrients; and (4) nutritional imbalances. Excesses of nutrients that interfere with the absorption or increase the excretion of magnesium-such as fat, phosphate, sugar, and vitamin D-can contribute to long-lasting relative magnesium deficiency. All have been implicated in several of the diseases considered in this book. Whether their influence on the need for magnesium is a common denominator remains to be investigated further.

Manganese in Health and Disease

Manganese in Health and Disease PDF Author: Lucio G Costa
Publisher: Royal Society of Chemistry
ISBN: 1782622381
Category : Medical
Languages : en
Pages : 655

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Book Description
Manganese in the diet is nutritionally essential for normal physiologic functioning. However, excessive exposure to manganese has been associated with developmental, neurodegenerative and other disorders. The book comprehensively covers the toxicology of manganese. Leading investigators provide perspectives from toxicology, neuroscience, nutrition, molecular biology and risk assessment disciplines and chapters cover the toxicokinetics, toxicodynamic interactions and health effects of manganese, as well as its potential role in neurodegenerative diseases. A large section devoted to health effects presents the latest research that associates manganese exposure to potential human diseases. Any scientists, health professional or regulator involved with metal exposure and toxicology should find this volume essential reading. Students and researchers in neurotoxicology will also find this book a useful reference.

Modern Nutrition in Health and Disease

Modern Nutrition in Health and Disease PDF Author: A. Catherine Ross
Publisher: Jones & Bartlett Learning
ISBN: 1284229858
Category : Health & Fitness
Languages : en
Pages : 1645

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Book Description
This widely acclaimed book is a complete, authoritative reference on nutrition and its role in contemporary medicine, dietetics, nursing, public health, and public policy. Distinguished international experts provide in-depth information on historical landmarks in nutrition, specific dietary components, nutrition in integrated biologic systems, nutritional assessment through the life cycle, nutrition in various clinical disorders, and public health and policy issues. Modern Nutrition in Health and Disease, Eleventh Edition, offers coverage of nutrition's role in disease prevention, international nutrition issues, public health concerns, the role of obesity in a variety of chronic illnesses, genetics as it applies to nutrition, and areas of major scientific progress relating nutrition to disease.

Diet and Health

Diet and Health PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309039940
Category : Medical
Languages : en
Pages : 765

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Book Description
Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.

Transdermal Magnesium Therapy

Transdermal Magnesium Therapy PDF Author: Dr. Mark Sircus
Publisher: iUniverse
ISBN: 145028356X
Category : Medical
Languages : en
Pages : 360

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Book Description
This second edition of Transdermal Magnesium Therapy offers a full medical review of how magnesium affects cancer, the heart, diabetes, the emotions, inflammation, surgery, autism, transdermal medicine, and so much more. Magnesium is nothing short of a miracle; it has the potential to save you from considerable suffering and pain. The information presented here could even save your life. Magnesium is the lamp of life and one of the most important keys to overall health. When applied in the correct way, magnesium offers us a return to strength and vigor. When used in the emergency room, magnesium can save the day for both heart and stroke patients. What you will be introduced to is magnesium oil, a natural concentrated form of magnesium chloride that can be applied directly to the skin for intense effect. When we are deficient in magnesium, over three hundred enzymes in our body are unable to function properly. Magnesium deficiency has been scientifically identified as a critical factor in the onset of a wide variety of diseases. For various reasons and to varying degree, two-thirds or more of the population is magnesium deficient. Learn how to use this powerful secret to good health in Transdermal Magnesium Therapy.

The Magnesium Factor

The Magnesium Factor PDF Author: Mildred Seelig
Publisher: Penguin
ISBN: 9781583331569
Category : Health & Fitness
Languages : en
Pages : 388

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Book Description
This important book brings to light an often overlooked but central factor in some of the most prevalent and serious disorders that affect Americans today: magnesium deficiency. Written by a medical doctor and researcher who is considered to be the world's leading expert on the actions and uses of this vital mineral, The Magnesium Factor explains how magnesium deficiencies develop, why they are so widespread, and how they translate into metabolic disruptions that ultimately threaten the health of virtually every bodily system. The author then details how to determine whether you have, or are at risk for, this problem-and what you can do about it. Backed by the latest scientific research, yet written in a clear, accessible style, here is the authoritative source for information on a topic of critical interest for all health-conscious individuals.

The Magnesium Miracle (Second Edition)

The Magnesium Miracle (Second Edition) PDF Author: Carolyn Dean, M.D., N.D.
Publisher: Ballantine Books
ISBN: 0425286711
Category : Health & Fitness
Languages : en
Pages : 610

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Book Description
Now updated with 30 percent new material, the only comprehensive guide to one of the most essential but often-overlooked minerals, magnesium—which guards against and helps to alleviate heart disease, stroke, osteoporosis, diabetes, depression, arthritis, and asthma Magnesium is an essential nutrient, indispensable to your health and well-being. By adding this mineral to your diet, you are guarding against—and helping to alleviate—such threats as heart disease, stroke, osteoporosis, diabetes, depression, arthritis, and asthma. But despite magnesium’s numerous benefits, many Americans remain dangerously deficient. Updated and revised throughout with the latest research, this amazing guide explains the vital role that magnesium plays in your body and life. Inside you will discover • new findings about the essential role of magnesium in lowering cholesterol • improved methods for increasing magnesium intake and absorption rate • how calcium can increase the risk of heart disease—and how magnesium can lower it • a magnesium-rich eating plan as delicious as it is healthy • information on the link between magnesium and obesity • vitamins and minerals that work with magnesium to treat specific ailments • why paleo, raw food, and green juice diets can lead to magnesium deficiency The Magnesium Miracle, now more than ever, is the ultimate guide to a mineral that is truly miraculous. Praise for The Magnesium Miracle “Dr. Carolyn Dean has been light-years ahead of her time when it comes to the crucial mineral magnesium and its many lifesaving uses. Her work is a gift to humanity. I highly recommend it.”—Christiane Northrup, M.D. “Throughout this volume and with utmost clarity, Dr. Carolyn Dean presents invaluable recommendations—based on the latest magnesium research. Virtually every American can benefit.”—Paul Pitchford, author of Healing with Whole Foods “Dr. Carolyn Dean has the best credentials for bringing solutions to those suffering from the hidden magnesium disorders that affect most of us. This book needs to be read by anyone wishing to improve their quality of life.”—Stephen T. Sinatra, M.D., author of The Sinatra Solution: Metabolic Cardiology

Calcium and Magnesium in Drinking-water

Calcium and Magnesium in Drinking-water PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241563559
Category : Business & Economics
Languages : en
Pages : 194

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Book Description
Can calcium and magnesium ("hardness") in drinking water contribute to preventing disease? This book documents the outputs of an unprecedented group of experts assembled by the World Health Organization to address this question. It includes their comprehensive consensus view on what is known and what is not about the role and possible health benefit of calcium and magnesium in drinking-water. Also included is a series of chapters each authored by internationally renowned experts reviewing the state of the art in different aspects including: global dietary calcium and magnesium intakes; the contribution of drinking water to calcium and magnesium intake; health significance of calcium and magnesium; role of drinking-water in relation to bone metabolism; epidemiological studies and the association of cardiovascular disease risks with water hardness and magnesium in particular; water production; technical issues and economics. In both developed and developing countries, typical diets are often deficient in calcium and magnesium--essential minerals which are necessary for the development of strong bones and teeth, and for cardiovascular function. At the same time, there is evidence that consuming "hard" drinking-water may be associated with reduced risks for some diseases. Climate change and other ongoing changes will increase the use of high tech treatments--for example desalination and reclamation of polluted waters and mean that the issue will be of increasing future importance.