Long-term Exposure to Ambient Air Pollution and Trajectories of Cognitive Decline in Northern Manhattan

Long-term Exposure to Ambient Air Pollution and Trajectories of Cognitive Decline in Northern Manhattan PDF Author: Erin Ryan Kulick
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description
I did not observe conclusive evidence of an association between air pollution and cognition in models stratified by APOE-4 status. To my knowledge, this is the largest study to analyze the association of ambient air pollution on cognition and cognitive decline over time in a racially and ethnically diverse sample. These results further support the current evidence on the role of air pollution on accelerated cognitive aging and brain health.

Long-term Exposure to Ambient Air Pollution and Trajectories of Cognitive Decline in Northern Manhattan

Long-term Exposure to Ambient Air Pollution and Trajectories of Cognitive Decline in Northern Manhattan PDF Author: Erin Ryan Kulick
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description
I did not observe conclusive evidence of an association between air pollution and cognition in models stratified by APOE-4 status. To my knowledge, this is the largest study to analyze the association of ambient air pollution on cognition and cognitive decline over time in a racially and ethnically diverse sample. These results further support the current evidence on the role of air pollution on accelerated cognitive aging and brain health.

The Role of Chronic Exposure to Ambient Air Pollution in Dementia and Cognitive Aging

The Role of Chronic Exposure to Ambient Air Pollution in Dementia and Cognitive Aging PDF Author: Sindana Devayani Ilango
Publisher:
ISBN:
Category :
Languages : en
Pages : 111

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Book Description
As average life-expectancy increases worldwide, there is a heightened public health concern about impaired cognitive function and dementia with advancing age. There are an estimated 10 million new cases of dementia each year and the worldwide prevalence is expected to triple by 2050. Without current effective treatment, research has expanded to identify modifiable risk factors for dementia to promote healthy cognitive aging. Air pollution is a unique modifiable risk factor as levels can be shaped by individual behaviors and population-level environmental policies and regulations. Ambient air pollution is a mixture of particulate matter, gases, and other organic and metallic components. Emerging evidence suggests chronic exposure may affect diseases of the central nervous system, including dementia and cognitive impairment. It is biologically plausible that increased exposure to air pollution can produce a neuroinflammatory response, which in turn can result in structural changes in the brain. Although epidemiologic studies have observed a link among some populations, the causal pathway between air pollution and dementia remains unclear and these studies are subject to specific methodological challenges. The first chapter of this dissertation reviews the epidemiological evidence regarding the relationship between dementia, cognitive impairment, and air pollution and outlines some methodological challenges my research addresses. The second chapter demonstrates different methods to account for competing events in a cohort of older adults in France and provides recommendations for future research in studies of air pollution and dementia. The third chapter examines the causal pathway between air pollution and dementia, evaluating cardiovascular disease as a potential intermediate in a population-based cohort in Ontario, Canada. The fourth chapter expands the generalizability of the current research by examining the relationship between air pollution and cognitive impairment in a US cohort of Hispanic/Latino adults, an understudied ethnic group with well-documented disparities in both air pollution exposure and chronic health outcomes. The final chapter of this dissertation summarizes key findings and highlights future directions to advance epidemiologic research of air pollution and cognitive aging.

The Impact of Short Term Exposure to Ambient Air Pollution on Cognitive Performance and Human Capital Formation

The Impact of Short Term Exposure to Ambient Air Pollution on Cognitive Performance and Human Capital Formation PDF Author: Victor Lavy
Publisher:
ISBN:
Category : Educational attainment
Languages : en
Pages : 22

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Book Description
Cognitive performance is critical to productivity in many occupations and potentially linked to pollution exposure. We evaluate this potentially important relationship by estimating the effect of pollution exposure on standardized test scores among Israeli high school high-stakes tests (2000-2002). Since students take multiple exams on multiple days in the same location after each grade, we can adopt a fixed effects strategy estimating models with city, school, and student fixed effects. We focus on fine particulate matter (PM2.5) and carbon monoxide (CO), which are considered to be two of the most dangerous forms of air pollution. We find that while PM2.5 and CO levels are only weakly correlated with each other, both exhibit a robust negative relationship with test scores. We also find that PM2.5, which is thought to be particularly damaging for asthmatics, has a larger negative impact on groups with higher rates of asthma. For CO, which affects neurological functioning, the effect is more homogenous across demographic groups. Furthermore, we find that exposure to either pollutant is associated with a significant decline in the probability of not receiving a Bagrut certificate, which is required for college entrance in Israel. The results suggest that the gain from improving air quality may be underestimated by a narrow focus on health impacts. Insofar as air pollution may lead to reduced cognitive performance, the consequences of pollution may be relevant for a variety of everyday activities that require mental acuity. Moreover, by temporarily lowering the productivity of human capital, high pollution levels lead to allocative inefficiency as students with lower human capital are assigned a higher rank than their more qualified peers. This may lead to inefficient allocation of workers across occupations, and possibly a less productive workforce.

Alzheimer's Disease and Air Pollution

Alzheimer's Disease and Air Pollution PDF Author: L. Calderón-Garcidueñas
Publisher: IOS Press
ISBN: 1643681591
Category : Medical
Languages : en
Pages : 616

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Book Description
Most people think of Alzheimer’s disease as a condition which predominately affects elderly people, but an increasing amount of evidence indicates that in populations exposed to high concentration of air pollutants, Alzheimer’s disease development and progression can be identified in pediatric and young adulthood ages. Cognitive, olfactory, gait, equilibrium and auditory alterations are seen early, thus the concept of decades-long asymptomatic period prior to clinical cognitive impairment does not apply to the millions of people exposed day in and day out to polluted environments. This book Alzheimer's Disease and Air Pollution – The Development and Progression of a Fatal Disease from Childhood and the Opportunities for Early Prevention is a compilation of work by researchers intent on revealing the links between air pollution and neurodegeneration. The book is divided into 6 sections. It includes a section describing the ways in which air pollution from traffic and tobacco smoke can damage the brain; epidemiological studies establishing a strong link between dementia and particulate matter and ozone; papers explaining the properties of pollution; and works describing the intricate pathways which transform normal neurons into ghost tangles surrounded by a devastated brain. Air pollution is complex; different pollutants, different sizes and shapes and different portals of entry, play different roles, but their capacity to damage neural tissue is abundantly illustrated in this book, which highlights the need for preventive measures to protect the millions of people currently exposed to air pollutants, and the need to ameliorate their harmful effects.

Dementia in Low and Middle Income Countries

Dementia in Low and Middle Income Countries PDF Author: Christopher Butler
Publisher: Frontiers Media SA
ISBN: 2889764265
Category : Medical
Languages : en
Pages : 381

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Book Description


Aging-friendly environments and healthy aging

Aging-friendly environments and healthy aging PDF Author: Yao Yao
Publisher: Frontiers Media SA
ISBN: 2832528694
Category : Medical
Languages : en
Pages : 299

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Book Description


Respiratory Health Effects of Airborne Hazards Exposures in the Southwest Asia Theater of Military Operations

Respiratory Health Effects of Airborne Hazards Exposures in the Southwest Asia Theater of Military Operations PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309679109
Category : Medical
Languages : en
Pages : 271

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Book Description
More than 3.7 million U.S. service members have participated in operations taking place in the Southwest Asia Theater of Military Operations since 1990. These operations include the 1990-1991 Persian Gulf War, a post-war stabilization period spanning 1992 through September 2001, and the campaigns undertaken in the wake of the September 11, 2001, attacks. Deployment to Iraq, Kuwait, Saudi Arabia, Bahrain, Gulf of Aden, Gulf of Oman, Oman, Qatar, the United Arab Emirates, and Afghanistan exposed service members to a number of airborne hazards, including oil-well fire smoke, emissions from open burn pits, dust and sand suspended in the air, and exhaust from diesel vehicles. The effects of these were compounded by stressors like excessive heat and noise that are inevitable attributes of service in a combat environment. Respiratory Health Effects of Airborne Hazards Exposures in the Southwest Asia Theater of Military Operations reviews the scientific evidence regarding respiratory health outcomes in veterans of the Southwest Asia conflicts and identifies research that could feasibly be conducted to address outstanding questions and generate answers, newly emerging technologies that could aid in these efforts, and organizations that the Veterans Administration might partner with to accomplish this work.

Impacts of Climate Change on Human Health in the United States

Impacts of Climate Change on Human Health in the United States PDF Author: US Global Change Research Program
Publisher: Simon and Schuster
ISBN: 1510726217
Category : Science
Languages : en
Pages : 592

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Book Description
As global climate change proliferates, so too do the health risks associated with the changing world around us. Called for in the President’s Climate Action Plan and put together by experts from eight different Federal agencies, The Impacts of Climate Change on Human Health: A Scientific Assessment is a comprehensive report on these evolving health risks, including: Temperature-related death and illness Air quality deterioration Impacts of extreme events on human health Vector-borne diseases Climate impacts on water-related Illness Food safety, nutrition, and distribution Mental health and well-being This report summarizes scientific data in a concise and accessible fashion for the general public, providing executive summaries, key takeaways, and full-color diagrams and charts. Learn what health risks face you and your family as a result of global climate change and start preparing now with The Impacts of Climate Change on Human Health.

The Ocean and Cryosphere in a Changing Climate

The Ocean and Cryosphere in a Changing Climate PDF Author: Intergovernmental Panel on Climate Change (IPCC)
Publisher: Cambridge University Press
ISBN: 9781009157971
Category : Science
Languages : en
Pages : 755

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Book Description
The Intergovernmental Panel on Climate Change (IPCC) is the leading international body for assessing the science related to climate change. It provides policymakers with regular assessments of the scientific basis of human-induced climate change, its impacts and future risks, and options for adaptation and mitigation. This IPCC Special Report on the Ocean and Cryosphere in a Changing Climate is the most comprehensive and up-to-date assessment of the observed and projected changes to the ocean and cryosphere and their associated impacts and risks, with a focus on resilience, risk management response options, and adaptation measures, considering both their potential and limitations. It brings together knowledge on physical and biogeochemical changes, the interplay with ecosystem changes, and the implications for human communities. It serves policymakers, decision makers, stakeholders, and all interested parties with unbiased, up-to-date, policy-relevant information. This title is also available as Open Access on Cambridge Core.

Managing the Risks of Extreme Events and Disasters to Advance Climate Change Adaptation

Managing the Risks of Extreme Events and Disasters to Advance Climate Change Adaptation PDF Author: Intergovernmental Panel on Climate Change
Publisher: Cambridge University Press
ISBN: 1107025060
Category : Business & Economics
Languages : en
Pages : 593

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Book Description
Extreme weather and climate events, interacting with exposed and vulnerable human and natural systems, can lead to disasters. This Special Report explores the social as well as physical dimensions of weather- and climate-related disasters, considering opportunities for managing risks at local to international scales. SREX was approved and accepted by the Intergovernmental Panel on Climate Change (IPCC) on 18 November 2011 in Kampala, Uganda.