Locus Coeruleus, Vigilance and Stress: Brain Mechanisms of Adaptive Behavioral Responsiveness PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Locus Coeruleus, Vigilance and Stress: Brain Mechanisms of Adaptive Behavioral Responsiveness PDF full book. Access full book title Locus Coeruleus, Vigilance and Stress: Brain Mechanisms of Adaptive Behavioral Responsiveness by . Download full books in PDF and EPUB format.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Get Book Here
Book Description
We have recorded electrical activity from more than 200 neurons in the locus coeruleus (LC) in 2 behaving monkeys during the last year. We have made significant technical advances (e.g., use of 10 micrometers-diameter microwires for recordings, increased accuracy of electrode penetrations) which have increased the quality and quantity of data obtained. Results confirm our preliminary findings of the last period, i.e., LC neurons vary activity physically and tonically during a vigilance task indicating a role for the LC system in regulating attentional lability and adaptive responsiveness to urgent stimuli. Moreover, extensive analysis of reversal performance reveals that LC neurons may have a close relationship with cognitive processes underlying stimulus analysis and decision-making. Finally, this analysis also reveals that LC neurons alter their responsiveness to stimuli after reversal of cue meaning in advance of corresponding alterations in behavioral responsiveness, indicating that LC neurons may play an important role in early learning processes, helping to 'entrain' other brain systems to respond adaptively to new significant stimuli.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Get Book Here
Book Description
We have recorded electrical activity from more than 200 neurons in the locus coeruleus (LC) in 2 behaving monkeys during the last year. We have made significant technical advances (e.g., use of 10 micrometers-diameter microwires for recordings, increased accuracy of electrode penetrations) which have increased the quality and quantity of data obtained. Results confirm our preliminary findings of the last period, i.e., LC neurons vary activity physically and tonically during a vigilance task indicating a role for the LC system in regulating attentional lability and adaptive responsiveness to urgent stimuli. Moreover, extensive analysis of reversal performance reveals that LC neurons may have a close relationship with cognitive processes underlying stimulus analysis and decision-making. Finally, this analysis also reveals that LC neurons alter their responsiveness to stimuli after reversal of cue meaning in advance of corresponding alterations in behavioral responsiveness, indicating that LC neurons may play an important role in early learning processes, helping to 'entrain' other brain systems to respond adaptively to new significant stimuli.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 5
Get Book Here
Book Description
Methods were developed for recording from locus coeruleus (LC) neurons in behaving monkeys using a microwire electrode holder allowing easy electrode repositioning in vivo. These techniques have vastly improved our data collection, so that we now routinely record from over 100 LC neurons per animal. Recordings of individual neurons are stable for periods of 30 min to 4 h. Methods were also developed for computer presentation of stimuli and task control in an oddball visual discrimination task. Other development included computer methods for data acquisition and analysis (on a separate machine) during this task. Results indicated that most LC neurons are activated selectively for target stimuli during this task; they are not activated appreciably by nontarget stimuli. In addition, preliminary results suggest that tonic LC activity varies closely with the animal's attentiveness to the task. These results indicate that very small changes in the tonic discharge rate of LC neurons may produce marked changes in attentiveness, and that focused, attentive behavior may demand an intermediate level of LC discharge combined with robust phasic responses to meaningful sensory stimuli.
Author: Attila Köfalvi
Publisher: Springer Science & Business Media
ISBN: 0387743499
Category : Medical
Languages : en
Pages : 587
Get Book Here
Book Description
Endocannabinoids have tremendous therapeutic potential. This book introduces readers to our current understanding of the neurobiology of endocannabinoids and related systems, detailing their pathophysiological role and therapeutic potential. Authors, experienced clinical investigators, present and analyze results of recent clinical trials as well as the development of new therapeutic strategies and medicines.
Author:
Publisher:
ISBN:
Category : Aeronautics
Languages : en
Pages : 464
Get Book Here
Book Description
Author: Hubert Vaudry
Publisher: Springer Science & Business Media
ISBN: 9781402073069
Category : Medical
Languages : en
Pages : 432
Get Book Here
Book Description
Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.
Author:
Publisher: Academic Press
ISBN: 008058134X
Category : Medical
Languages : en
Pages : 1129
Get Book Here
Book Description
This volume in Advances in Pharmacology focuses on all aspects of catecholamine research, from very basic to medical. It is broad based and covers many areas within physiology and medicine.
Author: George Fink
Publisher: Academic Press
ISBN: 0128011378
Category : Medical
Languages : en
Pages : 503
Get Book Here
Book Description
Stress: Concepts, Cognition, Emotion, and Behavior: Handbook in Stress Series, Volume 1, examines stress and its management in the workplace and is targeted at scientific and clinical researchers in biomedicine, psychology, and some aspects of the social sciences. The audience is appropriate faculty and graduate and undergraduate students interested in stress and its consequences. The format allows access to specific self-contained stress subsections without the need to purchase the whole nine volume Stress handbook series. This makes the publication much more affordable than the previously published four volume Encyclopedia of Stress (Elsevier 2007) in which stress subsections were arranged alphabetically and therefore required purchase of the whole work. This feature will be of special significance for individual scientists and clinicians, as well as laboratories. In this first volume of the series, the primary focus will be on general stress concepts as well as the areas of cognition, emotion, and behavior. Offers chapters with impressive scope, covering topics including the interactions between stress, cognition, emotion and behaviour Features articles carefully selected by eminent stress researchers and prepared by contributors representing outstanding scholarship in the field Includes rich illustrations with explanatory figures and tables Includes boxed call out sections that serve to explain key concepts and methods Allows access to specific self-contained stress subsections without the need to purchase the whole nine volume Stress handbook series
Author: George S. Jr. Everly
Publisher: Springer Science & Business Media
ISBN: 0306478005
Category : Psychology
Languages : en
Pages : 482
Get Book Here
Book Description
This updated edition covers a range of new topics, including stress and the immune system, post-traumatic stress and crisis intervention, Eye Movement Desensitization and Reprocessing (EMDR), Critical Incident Stress Debriefing (CISD), Crisis Management Briefings in response to mass disasters and terrorism, Critical Incident Stress Management (CISM), spirituality and religion as stress management tools, dietary factors and stress, and updated information on psychopharmacologic intervention in the human stress response. It is a comprehensive and accessible guide for students, practitioners, and researchers in the fields of psychology, psychiatry, medicine, nursing, social work, and public health.
Author: David Cantor
Publisher: Boydell & Brewer
ISBN: 1580464769
Category : Medical
Languages : en
Pages : 377
Get Book Here
Book Description
This edited volume explores the emergence of the stress concept and its ever-changing definitions; its uses in making novel linkages between disciplines such as ecology, physiology, psychology, psychiatry, public health, urban planning, architecture, and a range of social sciences; its application in a variety of sites such as the battlefield, workplace, clinic, hospital, and home; and the emergence of techniques of stress management in a variety of different socio-cultural and scientific locations. In short, this volume explores what happened when stress entered the discourse around modernity.
Author: Robert J. Ursano
Publisher: Cambridge University Press
ISBN: 1107138493
Category : Medical
Languages : en
Pages : 367
Get Book Here
Book Description
This book presents a decade of advances in the psychological, biological and social responses to disasters, helping medics and leaders prepare and react.
