Legionellosis Diagnosis and Control in the Genomic Era PDF Download
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Author: Rachel E Gibbs
Publisher:
ISBN: 9781913652531
Category : Science
Languages : en
Pages : 344
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Book Description
Author: Rachel E Gibbs
Publisher:
ISBN: 9781913652531
Category : Science
Languages : en
Pages : 344
Get Book Here
Book Description
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 030949382X
Category : Medical
Languages : en
Pages : 291
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Book Description
Legionnaires' disease, a pneumonia caused by the Legionella bacterium, is the leading cause of reported waterborne disease outbreaks in the United States. Legionella occur naturally in water from many different environmental sources, but grow rapidly in the warm, stagnant conditions that can be found in engineered water systems such as cooling towers, building plumbing, and hot tubs. Humans are primarily exposed to Legionella through inhalation of contaminated aerosols into the respiratory system. Legionnaires' disease can be fatal, with between 3 and 33 percent of Legionella infections leading to death, and studies show the incidence of Legionnaires' disease in the United States increased five-fold from 2000 to 2017. Management of Legionella in Water Systems reviews the state of science on Legionella contamination of water systems, specifically the ecology and diagnosis. This report explores the process of transmission via water systems, quantification, prevention and control, and policy and training issues that affect the incidence of Legionnaires' disease. It also analyzes existing knowledge gaps and recommends research priorities moving forward.
Author: Ronald P. de Vries
Publisher: Caister Academic Press Limited
ISBN: 9781910190395
Category : Medical
Languages : en
Pages : 0
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Book Description
Genome sequencing has affected studies into the biology of all classes of organisms and this is certainly true for filamentous fungi. The level with which biological systems can be studied since the availability of genomes and post-genomic technologies is beyond what most people could have imagined previously. The fungal genera Aspergillus and Penicillium contain some species that are amongst the most widely used industrial microorganisms and others that are serious pathogens of plants, animals and humans. These genera are also at the forefront of fungal genomics with many genome sequences available and a whole genus genome sequencing project in progress for Aspergillus. This book highlights some of the changes in the studies into these fungi, since the availability of genome sequences. The contributions vary from insights in the taxonomy of these genera, use of genomics for forward genetics and genomic adaptations, to specific stories addressing virulence, carbon starvation, sulphur metabolism, feruloyl esterases, secondary metabolism and pH modulation, to the development of novel methodology for use in parallel to genome sequencing. It therefore provides a taste of the current status of research in Penicillium and Aspergillus and a promise of many more things to come. An essential reference for everyone working with Aspergillus and Penicillium and other filamentous fungi and the book is also recommended reading for everyone with an interest in fungal genomics.
Author: Ebbing Lautenbach
Publisher: Cambridge University Press
ISBN: 1107153166
Category : Medical
Languages : en
Pages : 455
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Book Description
A clear, hands-on outline of best practices for infection prevention that directly improve patient outcomes across the healthcare continuum.
Author: Raj S. Bhopal
Publisher: Oxford University Press
ISBN: 0198739680
Category : Medical
Languages : en
Pages : 481
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Book Description
First edition published in 2002. Second edition published in 2008.
Author: Franklin White
Publisher: Oxford University Press, USA
ISBN: 0199751900
Category : Medical
Languages : en
Pages : 378
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Book Description
Amid ongoing shifts world economic and political systems, the promise for future public health is more tenuous than ever. Will the today's economic systems sustain tomorrow's health? Will future generations inherit fair access to health and health care? The best hope for the health of future generations is the establishment of a well-grounded, global public health system for today. To that end, Global Public Health: Ecological Foundations addresses both the challenges and cooperative solutions of contemporary public health, all within a framework of social justice, environmental sustainability, and global cooperation. With an emphasis upon ecological foundations, this text approaches public health principles-history, foundations, topics, and applications-with a community-first perspective. By achieving global reach through cooperative, local interventions, this text illustrates that through the practice of public health we can also maintain the health of our world. Blending established wisdom with new perspectives, Global Public Health will stimulate better understanding of how the different streams of public health can work more synergistically to promote global health equity. It is a foundation on which future public health measures can be built and succeed.
Author: Justin D Radolf
Publisher:
ISBN: 9781913652616
Category :
Languages : en
Pages : 770
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Book Description
Lyme disease (Lyme borreliosis) is the most prevalent vector-borne illness in the United States and Europe and a growing threat to global health. In addition Lyme disease is considered a model system of emerging infectious diseases. The book Borrelia: Molecular Biology, Host Interaction and Pathogenesis published in 2010 was the first state-of-the-art reference work covering the myriad, interlaced facets of the enzootic disorders caused by pathogenic Borrelia. This current volume, by the same editors, builds on the previous work and contains a vast amount of new information, a wider scope, and increased coverage of genomics, genetics, evolutionary biology, vector biology, physiology, pathogenicity, immune response, and immune evasion. Written by renowned scientists who have made seminal contributions to the field, this book contains an expansive treatment of the options to track live spirochetes and evaluate gene expression in ticks and mice, provides insights into the workings of the flagellar motor, presents up-to-date research on the modulation of gene expression, and reviews recent studies on the Lyme disease spirochete's networks of regulatory pathways. The volume highlights and describes in detail the tremendous advances in understanding of the Borrelia genus at the molecular and cellular levels as well as the pathogenesis of Lyme disease and relapsing fever. This comprehensive volume is indispensable for anyone involved in Borrelia and Lyme disease research and is highly recommended for microbiologists, immunologists, and physicians with an interest in spirochetes, vector-borne illness, or emerging infectious diseases. The book is a recommended reference volume for all microbiology libraries.
Author: Jeremy Hawker
Publisher: John Wiley & Sons
ISBN: 1119328055
Category : Medical
Languages : en
Pages : 481
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Book Description
The essential guide to controlling and managing today’s communicable diseases The fourth edition of Communicable Disease Control and Health Protection Handbook offers public health workers of all kinds an authoritative and up-to-date guide to current protocols surrounding the identification and control of infectious diseases. With its concise, accessible design, the book is a practical tool that can be relied upon to explain topics ranging from the basic principles of communicable disease control to recent changes and innovations in health protection practice. Major syndromes and individual infections are insightfully addressed, while the authors also outline the WHO’s international health regulations and the organizational arrangements in place in all EU nations. New to the fourth edition are chapters on Ebola, the Zika virus, and other emerging pandemics. In addition, new writing on healthcare-associated infection, migrant and refugee health, and the importance of preparedness make this an essential and relevant text for all those in the field. This vital resource: Reflects recent developments in the science and administration of health protection practice Covers topics such as major syndromes, control of individual infections, main services and activities, arrangements for all European countries, and much more Includes new chapters on the Zika virus, Schistosomiasis, Coronavirus including MERS + SARS, and Ebola Follows a format designed for ease of use and everyday consultation Created to provide public and environmental health practitioners, physicians, epidemiologists, infection control nurses, microbiologists and trainees with a straightforward – yet informative – resource, Communicable Disease Control and Health Protection Handbook is a practical companion for all those working the field today.
Author: Centers for Disease Control and Prevention CDC
Publisher: Oxford University Press
ISBN: 0190628634
Category : Medical
Languages : en
Pages : 705
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Book Description
THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.
Author: Ignacio López-Goñi
Publisher: Caister Academic Press Limited
ISBN: 9781904455936
Category : Science
Languages : en
Pages : 0
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Book Description
Brucella is a genus of Gram-negative, facultative, intracellular bacteria that are highly pathogenic for a variety of mammals, including humans. Recently, the World Health Organization cited brucellosis to be the world's most widespread zoonosis. An important feature of the pathogenicity of these organisms is their ability to survive and replicate within the host macrophages. However, the mechanism for this is unclear. In addition, none of the classical bacterial virulence factors found in other bacterial pathogens have been found in the genomes of the 40 Brucella species and biovars analyzed to date. Nevertheless, the application of systems biology approaches in recent years has transformed research, permitting fascinating new insights into Brucella molecular biology and genomics. Written by highly acclaimed Brucella scientists, this book comprehensively reviews the most important advances in the field. The opening chapters focus on genetic diversity within Brucella, covering both classical and new species. Particular emphasis is given to how comparative genomics has led to advances in molecular diagnostics, taxonomy, and phylogeny. Additional chapters cover proteomic analysis, transcriptomic analysis, the VirB type IV secretion system, signaling complexes - e.g. the BvrR/BvrS two-component regulatory system and quorum sensing. These chapters highlight the intricate interplay between factors involved in virulence. Another chapter discusses the role of the Brucella cell envelope in bacterial virulence and evasion of host defenses, and the final two chapters review the current strategies for the development of novel antibacterial agents and improved vaccines. This volume is essential reading for everyone with an interest in Brucella and brucellosis. It is also recommended for cellular microbiologists and immunologists, and vaccine development scientists, as well as a wider body of scientists, veterinarians, and MDs with an interest in microbial diagnostics, microbial pathogenesis, and host-parasite interactions.
