Kinetics and Dynamics of Intravenous Anesthetics

Kinetics and Dynamics of Intravenous Anesthetics PDF Author: G.M. Woerlee
Publisher: Springer Science & Business Media
ISBN: 0585280096
Category : Medical
Languages : en
Pages : 262

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Book Description
Many drugs used in current anesthetic practice are administered intravenously. An appreciation of their kinetics and dynamics is of great assistance in determining the most appropriate drug to use, and optimal dosage regimens for any given patient. This book is specially oriented to the requirements of anesthesiologists. It will enable the student of those subjects to gain enough knowledge to make these subjects usable in daily anesthetic practice. As such it is intermediate in difficulty between mathematically oriented texts, and those which only offer a very qualitative understanding of these subjects. Practical applications and examples of the uses to which kinetic and dynamic principles can be put in daily practice are emphasized and illustrated. Basic principles and techniques with which the reader can perform kinetic and dynamic calculations are explained simply and demonstrated in detail using examples derived from clinical practice. Two appendices provide kinetic and dynamic data on the most commonly used anesthetic drugs. The last chapters use the principles discussed in the first chapters to show how variations of normal physiology and disease affect drug kinetics and dynamics. This is especially valuable to the clinician as it enables clinically useful, albeit qualitative, predictions to be made of the direction of any change of kinetic and dynamic parameters of drugs due to these factors.

Kinetics and Dynamics of Intravenous Anesthetics

Kinetics and Dynamics of Intravenous Anesthetics PDF Author: G.M. Woerlee
Publisher: Springer Science & Business Media
ISBN: 0585280096
Category : Medical
Languages : en
Pages : 262

Get Book Here

Book Description
Many drugs used in current anesthetic practice are administered intravenously. An appreciation of their kinetics and dynamics is of great assistance in determining the most appropriate drug to use, and optimal dosage regimens for any given patient. This book is specially oriented to the requirements of anesthesiologists. It will enable the student of those subjects to gain enough knowledge to make these subjects usable in daily anesthetic practice. As such it is intermediate in difficulty between mathematically oriented texts, and those which only offer a very qualitative understanding of these subjects. Practical applications and examples of the uses to which kinetic and dynamic principles can be put in daily practice are emphasized and illustrated. Basic principles and techniques with which the reader can perform kinetic and dynamic calculations are explained simply and demonstrated in detail using examples derived from clinical practice. Two appendices provide kinetic and dynamic data on the most commonly used anesthetic drugs. The last chapters use the principles discussed in the first chapters to show how variations of normal physiology and disease affect drug kinetics and dynamics. This is especially valuable to the clinician as it enables clinically useful, albeit qualitative, predictions to be made of the direction of any change of kinetic and dynamic parameters of drugs due to these factors.

Kinetics and Dynamics of Intravenous Anesthetics

Kinetics and Dynamics of Intravenous Anesthetics PDF Author: G.M. Woerlee
Publisher: Springer Science & Business Media
ISBN: 0585280096
Category : Medical
Languages : en
Pages : 262

Get Book Here

Book Description
Many drugs used in current anesthetic practice are administered intravenously. An appreciation of their kinetics and dynamics is of great assistance in determining the most appropriate drug to use, and optimal dosage regimens for any given patient. This book is specially oriented to the requirements of anesthesiologists. It will enable the student of those subjects to gain enough knowledge to make these subjects usable in daily anesthetic practice. As such it is intermediate in difficulty between mathematically oriented texts, and those which only offer a very qualitative understanding of these subjects. Practical applications and examples of the uses to which kinetic and dynamic principles can be put in daily practice are emphasized and illustrated. Basic principles and techniques with which the reader can perform kinetic and dynamic calculations are explained simply and demonstrated in detail using examples derived from clinical practice. Two appendices provide kinetic and dynamic data on the most commonly used anesthetic drugs. The last chapters use the principles discussed in the first chapters to show how variations of normal physiology and disease affect drug kinetics and dynamics. This is especially valuable to the clinician as it enables clinically useful, albeit qualitative, predictions to be made of the direction of any change of kinetic and dynamic parameters of drugs due to these factors.

Kinetics and dynamics of intravenous anesthetics

Kinetics and dynamics of intravenous anesthetics PDF Author: Gerald M. Woerlee
Publisher:
ISBN: 9789090034034
Category :
Languages : en
Pages : 231

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Book Description


An Overview of TCI and TIVA

An Overview of TCI and TIVA PDF Author: Anthony Absolom
Publisher: Lannoo Publishers
ISBN: 9789038211077
Category :
Languages : en
Pages : 108

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Book Description
An Overview of TCI and TIVA was written by two pioneers in the field of targeted drug delivery in anesthesia. Despite its small size, this book is a rich source of information on the structure, function, and clinical applications of target-controlled infusion (TCI) systems. [...] The text has the appearance of class notes rather than a formal manual; however, this feature enhances the tutorial dynamics of the book and should attract individuals involved in learning such as anesthesia residents and specialists flirting with total intravenous anesthesia (TIVA).' - David O. Warner, editor of Anesthesiology. AUTHORS: Anthony Absolom is Professor of Anesthaesiology at the University of Groningen. Michel Struys is Professor on Anaesthesia at Ghent University and the Universal Medical Center Groningen and Director at the British Journal of Anaesthesia. 27 b/w images

Anesthetic Pharmacology

Anesthetic Pharmacology PDF Author: Alex S. Evers
Publisher: Cambridge University Press
ISBN: 1139497022
Category : Medical
Languages : en
Pages : 2902

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Book Description
In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

Modern Anesthetics

Modern Anesthetics PDF Author: Jürgen Schüttler
Publisher: Springer Science & Business Media
ISBN: 3540748067
Category : Medical
Languages : en
Pages : 497

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Book Description
Some important constraints of anesthesia must be taken into consideration when the pharmacological properties of modern anesthetics are discussed. The most imp- tant of these could be that the target effect be achieved preferably within seconds, at most within a few minutes. Similarly, offset of drug action should be achieved within minutes rather hours. The target effects, such as unconsciousness, are pot- tially life-threatening, as are the side effects of modern anesthetics, such as respi- tory and cardiovascular depression. Finally, the patient’s purposeful responses are not available to guide drug dosage, because, either the patient is unconscious, or more problematically, the patient is aware but unable to communicate pain because of neuromuscular blockade. These constraints were already recognised 35 years ago, when in 1972 Volume XXX entitled “Modern Inhalation Anesthetics” appeared in this Handbook Series. The present volume is meant as a follow up and extension of that volume. At the beginning of the 1970’s anesthesia was commonly delivered by inhalation, with only very few exceptions. The clinical understanding of that time considered anesthesia as a unique state achieved by any of the inhalation anesthetics, in- pendent of their specific molecular structure. “The very mechanism of anesthetic action at the biophase” was discussed within the theoretical framework of the “u- tary theory of narcosis”.

Veterinary Anesthesia and Analgesia

Veterinary Anesthesia and Analgesia PDF Author: Kurt A. Grimm
Publisher: John Wiley & Sons
ISBN: 1118526236
Category : Medical
Languages : en
Pages : 1072

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Book Description
Veterinary Anesthesia and Analgesia: the Fifth Edition of Lumb and Jones is a reorganized and updated edition of the gold-standard reference for anesthesia and pain management in veterinary patients. Provides a thoroughly updated edition of this comprehensive reference on veterinary anesthesia and analgesia, combining state-of-the-art scientific knowledge and clinically relevant information Covers immobilization, sedation, anesthesia, and analgesia of companion, wild, zoo, and laboratory animals Takes a body systems approach for easier reference to information about anesthetizing patients with existing conditions Adds 10 completely new chapters with in-depth discussions of perioperative heat balance, coagulation disorders, pacemaker implantation, cardiac output measurement, cardiopulmonary bypass, shelter anesthesia and pain management, anesthetic risk assessment, principles of anesthetic pharmacology, and more Now printed in color, with more than 400 images

Drug Interactions in Anesthesia

Drug Interactions in Anesthesia PDF Author: Norman Ty Smith
Publisher:
ISBN: 9780812109986
Category : Medical
Languages : en
Pages : 504

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Book Description


The Anaesthesia Science Viva Book

The Anaesthesia Science Viva Book PDF Author: Simon Bricker
Publisher: Cambridge University Press
ISBN: 9780521682480
Category : Medical
Languages : en
Pages : 356

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Book Description
The definitive guide to this part of the FRCA exam.

Clinical Ambulatory Anesthesia

Clinical Ambulatory Anesthesia PDF Author: Johan Raeder
Publisher: Cambridge University Press
ISBN: 1139488864
Category : Medical
Languages : en
Pages :

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Book Description
Ambulatory care can be a challenging setting in which to provide anesthesia – not all patients are suitable for rapid discharge post-operatively and opinions differ as to which types of surgery should be performed as day cases. This comprehensive guide delivers up-to-date, evidence-based advice on how to provide optimal anesthesia care for ambulatory surgery. Written by a leading clinical anesthesiologist, it provides clear guidance about how to handle particular patients in particular situations. The evidence and scientific knowledge for each issue are presented with reference to major studies and review papers, followed by practical advice based on the author's continuous clinical and scientific experience over 30 years. Topics include planning, equipping and staffing ambulatory units, pharmacology, basic concepts of ambulatory care, pre- and post-operative issues and current controversies. Clinical Ambulatory Anesthesia is essential reading for the clinical, postgraduate anesthesiologist as well as nurse anesthetists involved with ambulatory care.