Isotopes for Medicine and the Life Sciences

Isotopes for Medicine and the Life Sciences PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309176697
Category : Medical
Languages : en
Pages : 144

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Book Description
Radioactive isotopes and enriched stable isotopes are used widely in medicine, agriculture, industry, and science, where their application allows us to perform many tasks more accurately, more simply, less expensively, and more quickly than would otherwise be possible. Indeed, in many casesâ€"for example, biological tracersâ€"there is no alternative. In a stellar example of "technology transfer" that began before the term was popular, the Department of Energy (DOE) and its predecessors has supported the development and application of isotopes and their transfer to the private sector. The DOE is now at an important crossroads: Isotope production has suffered as support for DOE's laboratories has declined. In response to a DOE request, this book is an intensive examination of isotope production and availability, including the education and training of those who will be needed to sustain the flow of radioactive and stable materials from their sources to the laboratories and medical care facilities in which they are used. Chapters include an examination of enriched stable isotopes; reactor and accelerator-produced radionuclides; partnerships among industries, national laboratories, and universities; and national isotope policy.

Isotopes for Medicine and the Life Sciences

Isotopes for Medicine and the Life Sciences PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309176697
Category : Medical
Languages : en
Pages : 144

Get Book Here

Book Description
Radioactive isotopes and enriched stable isotopes are used widely in medicine, agriculture, industry, and science, where their application allows us to perform many tasks more accurately, more simply, less expensively, and more quickly than would otherwise be possible. Indeed, in many casesâ€"for example, biological tracersâ€"there is no alternative. In a stellar example of "technology transfer" that began before the term was popular, the Department of Energy (DOE) and its predecessors has supported the development and application of isotopes and their transfer to the private sector. The DOE is now at an important crossroads: Isotope production has suffered as support for DOE's laboratories has declined. In response to a DOE request, this book is an intensive examination of isotope production and availability, including the education and training of those who will be needed to sustain the flow of radioactive and stable materials from their sources to the laboratories and medical care facilities in which they are used. Chapters include an examination of enriched stable isotopes; reactor and accelerator-produced radionuclides; partnerships among industries, national laboratories, and universities; and national isotope policy.

Principles and Techniques of Biochemistry and Molecular Biology

Principles and Techniques of Biochemistry and Molecular Biology PDF Author: Keith Wilson
Publisher: Cambridge University Press
ISBN: 0521516358
Category : Medical
Languages : en
Pages : 769

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Book Description
Uniquely integrates the theory and practice of key experimental techniques for bioscience undergraduates. Now includes drug discovery and clinical biochemistry.

Nitrogen Isotope Techniques

Nitrogen Isotope Techniques PDF Author: Roger Knowles
Publisher: Academic Press
ISBN:
Category : Science
Languages : en
Pages : 336

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Book Description
This book is the first laboratory manual to bring together basic procedures for measurement of stable and radioactive isotopes of nitrogen, with specific applications to plant, soil, and aquatic biology. This bench-top reference gives practical coverage of mass and emission spectrometry, nitrogen fixation, nitrification, and identification, organic nitrogen, and the radioactive isotope 13N. Methods are described so that researchers can adapt them, without the aid of outside references, to virtually any task they may encounter in investigations of nitrogen transformation processes. Serves as a practical guide for nitrogen isotope techniques Features studies of nitrogen transformations in terrestrial and aquatic systems Includes basic measurement techniques plus specific applications for stable and radioactive nitrogen isotopes Presents detailed protocols, overviews, and key references Includes fifty figures and sixteen tables Hands-on reference for both students and researchers

Carbon Isotope Techniques

Carbon Isotope Techniques PDF Author: David C. Coleman
Publisher: Academic Press
ISBN: 032315767X
Category : Science
Languages : en
Pages : 287

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Book Description
Carbon Isotope Techniques deals with the use of carbon isotopes in studies of plant, soil, and aquatic biology. Topics covered include photosynthesis/translocation studies in terrestrial ecosystems; carbon relationships of plant-microbial symbioses; microbe/plant/soil interactions; and environmental and aquatic toxicology. Stable carbon isotope ratios of natural materials are also considered. Comprised of 15 chapters, this book begins with an introduction to radiation-counting instruments used in measuring the radioactivity in soil and plant samples containing carbon-14. The discussion then turns to the basic methods of 14C use in plant science, highlighted by three examples of applications in the field of plant physiology and ecology. Subsequent chapters explore the use of carbon isotope techniques for analyzing the carbon relationships of plant-microbial symbioses; the interactions of microbes, plants, and soils; and the degradation of herbicides and organic xenobiotics. Carbon dating and bomb carbon are also described. The final section is devoted to the uses and procedures for 13C and 11C. This monograph is intended for advanced undergraduate or graduate students, as well as generalist scientists who have not previously used radioisotopes or stable isotopes in their research.

Isotopes

Isotopes PDF Author: Rob Ellam
Publisher: Oxford University Press
ISBN: 0198723628
Category : Science
Languages : en
Pages : 153

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Book Description
Isotopes are used in many areas of science and technology, including medicine, archaeology, and nuclear physics. They are central to our understanding of the Earth's past and current processes. Here, Rob Ellam explains the importance and applications of stable and radioactive isotopes.

The Elements: A Very Short Introduction

The Elements: A Very Short Introduction PDF Author: Philip Ball
Publisher: Oxford University Press
ISBN: 0192840991
Category : Science
Languages : en
Pages : 193

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Book Description
This Very Short Introduction is an exciting and non-traditional approach to understanding the terminology, properties, and classification of chemical elements. It traces the history and cultural impact of the elements on humankind from ancient times through today. Packed with anecdotes, The Elements is a highly engaging and entertaining exploration of the fundamental question: what is the world made from?

Tracer Kinetics and Physiologic Modeling

Tracer Kinetics and Physiologic Modeling PDF Author: R.M. Lambrecht
Publisher: Springer
ISBN:
Category : Mathematics
Languages : en
Pages : 524

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Book Description
These lectures were prepared by the authors for Seminars to be held on June 6, 1983, in St.Louis, Missouri, under the spon­ sorship of the Radiopharmaceutical Science Council of the So­ ciety of Nuclear Medicine . All manuscript? were refereed . Tracer kinetics and the modeling of physiological and bio­ chemical processes in vivo are the focus of a contemporary di­ rection in biochemical research. Recent advances in instrumen­ tation (especially positron emission tomography and digital autoradiography) and parallel developments in the production of short-lived radionuclides and rapid synthetic chemistry to pre­ pare tracers that probe metabolism, flow, receptor-ligand kinetics, etc., are responsible for new scientific frontiers. These developments, coupled with biomathematics and computer science, make it possible to quantitatively evaluate tracer kinetic models in animals and man. (The choice of animal models in radiotracer design and tracer kinetics is the subject of a book edited by R.M.Lambrecht and W.C.Eckleman in press at Sprin­ ger Verlag.) Tracer kinetics and physiological modeling is truly multi­ disciplinary, as evidenced by the intellectual diversity and international representation observable in the list of contri­ butors . The lectures outline and attempt to show the transition from the theoretical description to the practical application of modeling for understanding normal and pathological processes .

Isotope Techniques in Biochemistry

Isotope Techniques in Biochemistry PDF Author: Norman Samuel Radin
Publisher:
ISBN:
Category : Biochemistry
Languages : en
Pages : 56

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Book Description


Isotope Effects

Isotope Effects PDF Author: Max Wolfsberg
Publisher: Springer Science & Business Media
ISBN: 9048122651
Category : Science
Languages : en
Pages : 477

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Book Description
As the title suggests, Isotope Effects in the Chemical, Geological and Bio Sciences deals with differences in the properties of isotopically substituted molecules, such as differences in the chemical and physical properties of water and the heavy waters. Since the various fields in which isotope effects are applied do not only share fundamental principles but also experimental techniques, this book includes a discussion of experimental apparatus and experimental techniques. Isotope Effects in the Chemical, Geological and Bio Sciences is an educational monograph addressed to graduate students and others undertaking isotope effect research. The fundamental principles needed to understand isotope effects are presented in appropriate detail. While it is true that these principles are more familiar to students of physical chemistry and some background in physical chemistry is recommended, the text provides enough detail to make the book an asset to students in organic and biochemistry, and geochemistry.

Stable Isotope Techniques in the Study of Biological Processes and Functioning of Ecosystems

Stable Isotope Techniques in the Study of Biological Processes and Functioning of Ecosystems PDF Author: M.J. Unkovich
Publisher: Springer Science & Business Media
ISBN: 940159841X
Category : Science
Languages : en
Pages : 312

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Book Description
In the last two decades technological advances in isotope ratio mass spectrometry have been very rapid, opening up new possibilities for analysis of biological and environmental materials. The new instrumentation has facilitated faster analysis of samples via automated sample preparation and multi-isotope analysis of single samples, resulting in considerable cost savings, and enabling access to isotope analysis for many more researchers. These changes are reflected in the rapidly growing international literature on stable isotopes. While there have been some excellent books and review papers aimed at interpreting isotope signals in biology and environmental science, there have been fewer attempts to provide practical tools for researchers making forays into this exciting new arena. This book aims to address this inadequacy by providing a set of practical guidelines for the application of a range of novel and well proven stable isotope techniques to the fields of plant physiological ecology, agriculture, marine ecology and palaeoecology. The book is the outcome of a weeklong workshop held under the auspices of the Cooperative Research Centre for Legumes in Mediterranean Agriculture (CLIMA 1992 - 2000) at The University of Western Australia and the CSIRO Floreat Laboratories, Perth, Western Australia, in February 1999. The workshop was designed to provide practical tools and experiences for researchers and students concerned with how one goes about using stable isotopes in field investigations.