Interplay between Autophagy and Metabolic Syndrome: Causes, Consequences and Therapeutic Challenges

Interplay between Autophagy and Metabolic Syndrome: Causes, Consequences and Therapeutic Challenges PDF Author: Joilson O. Martins
Publisher: Frontiers Media SA
ISBN: 288971747X
Category : Science
Languages : en
Pages : 224

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Metabolic Cardiomyopathy

Metabolic Cardiomyopathy PDF Author: H. Böhles
Publisher: CRC Press
ISBN: 9783887631048
Category : Cardiomyopathy
Languages : en
Pages : 188

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Book Description
During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with CDG-syndrome is included. It should be helpful, not only to cardiologists, paediatricians, internists and general practicioners, but also to all those interested in a better understanding of the metabolic basis of clinical disease entities.

ABC of Obesity

ABC of Obesity PDF Author: Naveed Sattar
Publisher: John Wiley & Sons
ISBN: 1444312707
Category : Medical
Languages : en
Pages : 64

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Book Description
Obesity is a hugely expensive and increasing problem worldwide,leading to disability, reproductive problems, depression andaccelerated metabolic and vascular diseases in a large proportionof men, women and children. The ABC of Obesity is a newguide which will aid its effective management, addressing issuessuch as dieting, exercise, self esteem, drug treatment and surgery.Recent evidence is used to highlight frequent problems, successfultreatment options, and the most common causes. Written by leading experts, this is a widely accessible text andan indispensable guide for all general practitioners, juniordoctors, nurses, and other healthcare professionals who areinvolved in the treatment and research of this commoncondition.

Mitochondrial Dysfunction

Mitochondrial Dysfunction PDF Author: Lawrence H. Lash
Publisher: Elsevier
ISBN: 1483218619
Category : Science
Languages : en
Pages : 527

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Book Description
Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.

Role of Autophagy and Reactive Oxygen Species in Cancer Treatment

Role of Autophagy and Reactive Oxygen Species in Cancer Treatment PDF Author: Neeraj Mishra
Publisher: Springer Nature
ISBN: 3031664213
Category :
Languages : en
Pages : 372

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Cancer as a Metabolic Disease

Cancer as a Metabolic Disease PDF Author: Thomas Seyfried
Publisher: John Wiley & Sons
ISBN: 1118310306
Category : Science
Languages : en
Pages : 482

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Book Description
The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism. However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited. This book aims to provide evidence, through case studies, that cancer is primarily a metabolic disease requring metabolic solutions for its management and prevention. Support for this position is derived from critical assessment of current cancer theories. Brain cancer case studies are presented as a proof of principle for metabolic solutions to disease management, but similarities are drawn to other types of cancer, including breast and colon, due to the same cellular mutations that they demonstrate.

Cross-Talk and Interaction between Endocrinology and Urology: Challenges and Opportunities

Cross-Talk and Interaction between Endocrinology and Urology: Challenges and Opportunities PDF Author: Xiao-qiang Liu
Publisher: Frontiers Media SA
ISBN: 2832536840
Category : Medical
Languages : en
Pages : 237

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Book Description
The genitourinary system is closely related to the endocrine system. Some genitourinary organs are endocrine organs themselves. Over the past decades, the diagnosis and treatment on both endocrine and urological diseases have developed rapidly. Concerns regarding the normal growth, development, and physiological functions of the genitourinary system, as well as the pathogenesis and treatment of urinary diseases have been raised. The diseases from these two different systems belong to the specialties of internal medicine and surgery respectively. For example, prostate is regulated by androgen originates from testis, adrenal and even malignancies. Androgen deprivation therapy has definite effect on prostatic adenocarcinoma but may also develop castration resistance. The disorders of gonad and reproductive health are also implicated in hormone regulation, such as delayed hypogonadism. Many diseases such as Cushing's syndrome and aldosteronism are transdisciplinary. However, the research on the normal physiological function, and the comprehensive diagnosis and treatment of both systems are short of cross-integration, resulting in a lack of close cooperation between physicians and surgeons. We are calling for more attention on the joint participation in multidisciplinary diagnosis and treatment, as well as collaboration on basic research in the field of genitourinary and endocrine diseases.

Metabolic Abnormalities and Breast Cancer: Challenges From Bench to Bedside

Metabolic Abnormalities and Breast Cancer: Challenges From Bench to Bedside PDF Author: Xiaosong Chen
Publisher: Frontiers Media SA
ISBN: 2889761878
Category : Medical
Languages : en
Pages : 211

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New Drug Targets for Proteotoxicity in Cardiometabolic Diseases

New Drug Targets for Proteotoxicity in Cardiometabolic Diseases PDF Author: Jun Ren
Publisher: Frontiers Media SA
ISBN: 2889715833
Category : Science
Languages : en
Pages : 310

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The Dynamic Interplay Between Nutrition, Autophagy and Cell Metabolism

The Dynamic Interplay Between Nutrition, Autophagy and Cell Metabolism PDF Author: Vincenzo Flati
Publisher: Frontiers Media SA
ISBN: 2889669084
Category : Science
Languages : en
Pages : 86

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Book Description