Insulin - the Crooked Timber

Insulin - the Crooked Timber PDF Author: Kersten T. Hall
Publisher: Oxford University Press
ISBN: 0192855387
Category : Medical
Languages : en
Pages : 476

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Book Description
Before the discovery of insulin, a diagnosis of Type 1 diabetes was a death sentence. To mark the centenary of this landmark in medicine, this book charts the journey of how insulin was transformed from what one clinician called 'thick brown muck' into the very first drug to be produced using genetic engineering, and which earned the founders of US biotech company Genentech a small fortune. Taking the reader on a fascinating journey, starting with the discovery of insulin in the 1920s through to the present day, Insulin - The Crooked Timber reveals a story of monstrous egos, toxic career rivalries, and a few unsung heroes and heroines. It discusses in detail the circumstances of Canadian scientist Frederick Banting whose award of the 1923 Nobel Prize for this life-saving discovery proved to be both a blessing and a curse for him and explores how the human story behind this discovery still remains one of ongoing political and scientific controversy. The book is the result of the author's own shocking diagnosis with Type 1 diabetes and its story reminds us all of what technology can - and cannot do - for us. As the world struggles to emerge from the COVID-19 pandemic and face future challenges such as climate change, the lessons that we can learn from the story of insulin have never been more important.

Insulin - the Crooked Timber

Insulin - the Crooked Timber PDF Author: Kersten T. Hall
Publisher: Oxford University Press
ISBN: 0192855387
Category : Medical
Languages : en
Pages : 476

Get Book Here

Book Description
Before the discovery of insulin, a diagnosis of Type 1 diabetes was a death sentence. To mark the centenary of this landmark in medicine, this book charts the journey of how insulin was transformed from what one clinician called 'thick brown muck' into the very first drug to be produced using genetic engineering, and which earned the founders of US biotech company Genentech a small fortune. Taking the reader on a fascinating journey, starting with the discovery of insulin in the 1920s through to the present day, Insulin - The Crooked Timber reveals a story of monstrous egos, toxic career rivalries, and a few unsung heroes and heroines. It discusses in detail the circumstances of Canadian scientist Frederick Banting whose award of the 1923 Nobel Prize for this life-saving discovery proved to be both a blessing and a curse for him and explores how the human story behind this discovery still remains one of ongoing political and scientific controversy. The book is the result of the author's own shocking diagnosis with Type 1 diabetes and its story reminds us all of what technology can - and cannot do - for us. As the world struggles to emerge from the COVID-19 pandemic and face future challenges such as climate change, the lessons that we can learn from the story of insulin have never been more important.

Freedom From the Market

Freedom From the Market PDF Author: Mike Konczal
Publisher: The New Press
ISBN: 1620975386
Category : Social Science
Languages : en
Pages : 258

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Book Description
The progressive economics writer redefines the national conversation about American freedom “Mike Konczal [is] one of our most powerful advocates of financial reform‚ [a] heroic critic of austerity‚ and a huge resource for progressives.”—Paul Krugman Health insurance, student loan debt, retirement security, child care, work-life balance, access to home ownership—these are the issues driving America’s current political debates. And they are all linked, as this brilliant and timely book reveals, by a single question: should we allow the free market to determine our lives? In the tradition of Naomi Klein’s The Shock Doctrine, noted economic commentator Mike Konczal answers this question with a resounding no. Freedom from the Market blends passionate political argument and a bold new take on American history to reveal that, from the earliest days of the republic, Americans have defined freedom as what we keep free from the control of the market. With chapters on the history of the Homestead Act and land ownership, the eight-hour work day and free time, social insurance and Social Security, World War II day cares, Medicare and desegregation, free public colleges, intellectual property, and the public corporation, Konczal shows how citizens have fought to ensure that everyone has access to the conditions that make us free. At a time when millions of Americans—and more and more politicians—are questioning the unregulated free market, Freedom from the Market offers a new narrative, and new intellectual ammunition, for the fight that lies ahead.

The Discovery of Insulin

The Discovery of Insulin PDF Author: Michael Bliss
Publisher: University of Toronto Press
ISBN: 1487529139
Category : Diabetes
Languages : en
Pages : 351

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Book Description
This special centenary edition of The Discovery of Insulin celebrates a path-breaking medical discovery that has changed lives around the world.

The Man in the Monkeynut Coat

The Man in the Monkeynut Coat PDF Author: Kersten T. Hall
Publisher: Oxford University Press (UK)
ISBN: 0198704593
Category : Biography & Autobiography
Languages : en
Pages : 255

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Book Description
Tells the story of the English physicist and molecular biologist William T. Astbury and how his work forms a previously untold chapter in the story of the discovery of the structure of DNA.

Breakthrough

Breakthrough PDF Author: Thea Cooper
Publisher: Macmillan + ORM
ISBN: 142996569X
Category : Medical
Languages : en
Pages : 319

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Book Description
An “inspirational” account of how a young girl plight’s “launched a boon for diabetics the world over . . . A remarkable story . . . worthy reading” (Booklist). It is 1919 and Elizabeth Hughes, the eleven-year-old daughter of America’s most-distinguished jurist and politician, Charles Evans HugheAs, has been diagnosed with juvenile diabetes. It is essentially a death sentence. The only accepted form of treatment—starvation—whittles her down to forty-five pounds of skin and bones. Miles away, Canadian researchers Frederick Banting and Charles Best manage to identify and purify insulin from animal pancreases—a miracle soon marred by scientific jealousy, intense business competition and fistfights. In a race against time and a ravaging disease, Elizabeth becomes one of the first diabetics to receive insulin injections—all while its discoverers and a little known pharmaceutical company struggle to make it available to the rest of the world. Relive the heartwarming true story of the discovery of insulin as it’s never been told before. Written with authentic detail and suspense, and featuring walk-ons by William Howard Taft, Woodrow Wilson, and Eli Lilly himself, among many others. “[A] fascinating tale of Nobel Prize–winning research. . . . This book is an important read for anyone with diabetes. It is an enjoyable read for those who love mystery and human drama.” —Kenneth T. Jackson, Barzun Professor of History, Columbia University

The Sinister Side

The Sinister Side PDF Author: James Hall
Publisher: Oxford University Press
ISBN: 0199230862
Category : Art
Languages : en
Pages : 506

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Book Description
The Sinister Side is the first book to detail the richness and subtlety of left-right symbolism since the Renaissance, and to show how it was a catalyst for some of the greatest works of visual art from Leonardo and Michelangelo to Rembrandt and Picasso. Traditionally, the left side was regarded as evil, weak, and worldly, but with the Renaissance, artists began to represent the left side as the side that represented authentic human feelings and especially love. Writers including Lorenzo de' Medici, Michelangelo, and Winckelmann hailed the supreme moral and aesthetic beauty of the left side. Images of lovers foreground the left side of the body, emphasizing its refinement and sensitivity. In the late nineteenth century, with the rise of interest in the occult and in spiritualism, the left side becomes associated with the taboo and with the unconscious. James Hall's insightful discussion of left and right symbolism helps us to see how the self and the mind were perceived during these periods, and gives us a new key to understanding art in its social and intellectual context.

The Emergence of the Fourth Dimension

The Emergence of the Fourth Dimension PDF Author: Mark Blacklock
Publisher: Oxford University Press
ISBN: 0192551884
Category : Literary Criticism
Languages : en
Pages : 384

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Book Description
The Emergence of the Fourth Dimension describes the development and proliferation of the idea of higher dimensional space in the late nineteenth- and early twentieth-centuries. An idea from mathematics that was appropriated by occultist thought, it emerged in the fin de siècle as a staple of genre fiction and influenced a number of important Modernist writers and artists. Providing a context for thinking of space in dimensional terms, the volume describes an active interplay between self-fashioning disciplines and a key moment in the popularisation of science. It offers new research into spiritualism and the Theosophical Society and studies a series of curious hybrid texts. Examining works by Joseph Conrad, Ford Madox Ford, H.G. Wells, Henry James, H. P. Lovecraft, and others, the volume explores how new theories of the possibilities of time and space influenced fiction writers of the period, and how literature shaped, and was in turn shaped by, the reconfiguration of imaginative space occasioned by the n-dimensional turn. A timely study of the interplay between philosophy, literature, culture, and mathematics, it offers a rich resource for readers interested in nineteenth century literature, Modernist studies, science fiction, and gothic scholarship.

Last Best Gifts

Last Best Gifts PDF Author: Kieran Healy
Publisher: University of Chicago Press
ISBN: 0226322386
Category : Social Science
Languages : en
Pages : 208

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Book Description
More than any other altruistic gesture, blood and organ donation exemplifies the true spirit of self-sacrifice. Donors literally give of themselves for no reward so that the life of an individual—often anonymous—may be spared. But as the demand for blood and organs has grown, the value of a system that depends solely on gifts has been called into question, and the possibility has surfaced that donors might be supplemented or replaced by paid suppliers. Last Best Gifts offers a fresh perspective on this ethical dilemma by examining the social organization of blood and organ donation in Europe and the United States. Gifts of blood and organs are not given everywhere in the same way or to the same extent—contrasts that allow Kieran Healy to uncover the pivotal role that institutions play in fashioning the contexts for donations. Procurement organizations, he shows, sustain altruism by providing opportunities to give and by producing public accounts of what giving means. In the end, Healy suggests, successful systems rest on the fairness of the exchange, rather than the purity of a donor’s altruism or the size of a financial incentive.

A Male Hysteria

A Male Hysteria PDF Author: Edward Beasley
Publisher: University of Pennsylvania Press
ISBN: 1606189026
Category : History
Languages : en
Pages : 457

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Book Description
"This book explores the history and treatment of diabetes. It focuses on the nineteenth-century understanding of the disease and medicine's attempts to grapple with the disorder for the past two centuries"--

The Genetic Age

The Genetic Age PDF Author: Matthew Cobb
Publisher: Profile Books
ISBN: 1782838031
Category : Medical
Languages : en
Pages : 403

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Book Description
A TIMES ENVIRONMENT AND SCIENCE BOOK OF THE YEAR 2022 'The ideal guide to what is not just a fiendishly complex area of science but also an ethical minefield' Mail on Sunday A new gene editing technology, invented just seven years ago, has turned humanity into gods. Enabling us to manipulate the genes in virtually any organism with exquisite precision, CRISPR has given scientists a degree of control that was undreamt of even in science fiction. But CRISPR is just the latest, giant leap in a long journey to master genetics. The Genetic Age shows the astonishing, world-changing potential of the new genetics and the possible threats it poses, sifting between fantasy and the reality when it comes to both benefits and dangers. By placing each phase of discovery, anticipation and fear in the context of over fifty years of attempts to master the natural world, Matthew Cobb, the Baillie-Gifford-shortlisted author of The Idea of the Brain, weaves the stories of science, history and culture to shed new light on our future. With the powers now at our disposal, it is a future that is almost impossible to imagine - but it is one we will create ourselves.