Author: Istvan Berczi
Publisher: Elsevier
ISBN: 012801833X
Category : Science
Languages : en
Pages : 312
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Book Description
Insights to Neuroimmune Biology, Second Edition discusses the systemic regulatory network, coordination, organization, and interpretation of the rapidly accumulating knowledge on the topic of neuroimmune biology, with an ultimate goal of helping readers understand the function of higher organisms, including man, in their entire complexity. This publication provides assessments and interpretations of accumulated experimental evidence, enabling the scientific community to keep abreast of essential advancements of existing knowledge as we search for greater understanding of the biology of higher organisms. - Provides information on the importance and applicability of the field of neuroimmunology - Describes subjects that have shown significant recent developments - Introduces a whole new dimension to neuroimmunology by discussing Epigenetic Immunoregulation - Investigates the mechanisms and functions of the Neuroimmune Regulatory Supersystem - Promotes translational research in the field of neuroimmune biology - Covers challenges, such as dealing with problems of e.g., hypothalamic regulation of immune functions, interrelationships of stress and disease, epigenetic immunoregulation, neuroprotection, and neuroimmune regulation in pregnancy.
Author: Istvan Berczi
Publisher: Elsevier
ISBN: 0123846927
Category : Science
Languages : en
Pages : 285
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Book Description
New Insights to Neuroimmune Biology investigates the mechanisms that and functions of the Neuroimmune Regulatory Supersystem. Covering molecular regulation of cytokines in brain astrocytes, immunoregulation by the sympathetic nervous system, circadian regulation of immune reactions, antigen recognition by the CNS, the modulation of the immune response by head injury, neurogenic inflammation, the role of tachykinins in asthma and allergic disease, defence and defeat reactions, cytokines, behavior and affective disorders, increased activity of type 1 helper T cell functions after reward stimulation.This book has relevance to the entire scientific community in Biology, Medicine and Veterinary medicine as it discusses molecular, cellular, organic and systemic aspects as well as the physological, pathophysiological and behavioral mechnisms which are involved in Neuroimmiune Biology.
Author: Valentin A. Pavlov
Publisher: Frontiers Media SA
ISBN: 2889455335
Category :
Languages : en
Pages : 222
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Book Description
The nervous system plays an important role in the regulation of immunity and inflammation. On the other hand unbalanced immune responses in inflammatory and autoimmune conditions may have a deleterious impact on neuronal integrity and brain function. Recent studies have characterized neural pathways communicating peripheral inflammatory signals to the CNS, and brain- and spinal cord-derived circuitries controlling various innate and adaptive immune responses and inflammation. A prototypical neural reflex circuit that regulates immunity and inflammation is the vagus nerve-based “inflammatory reflex”. Ongoing research has revealed cellular and molecular mechanisms underlying these neural circuits and indicated new therapeutic approaches in inflammatory and autoimmune disorders. Pharmacological and bioelectronic modulation of neural circuitry has been successfully explored in preclinical settings of sepsis, arthritis, inflammatory bowel disease, obesity-driven disorders, diabetes and other diseases. These studies paved the way to successful clinical trials with bioelectronic neuronal modulation in rheumatoid arthritis and inflammatory bowel disease. Dysregulated release of cytokines and other inflammatory molecules may have a severe impact on brain function. Brain inflammation (neuroinflammation), imbalances in brain neuronal integrity and neurotransmitter systems, and cognitive impairment are characteristic features of post-operative conditions, sepsis, liver diseases, diabetes and other disorders characterized by immune and metabolic dysregulation. Derangements in cytokine release also play a pivotal role in depression. Characteristic brain reactive antibodies in autoimmune conditions, including systemic lupus erythematosus and neuromyelitis optica, significantly contribute to brain pathology and cognitive impairment. These studies, and the simultaneous characterization of neuro-protective cytokines, identified new therapeutic approaches for treating neurological complications in inflammatory and autoimmune disorders. This Frontiers Research Topic is a forum for publishing research findings and methodological and conceptual advances at the intersection of immunology and neuroscience. We hope that presenting new insight into bi-directional neuro-immune communication in inflammation and autoimmunity will foster further collaborations and facilitate the development of new efficient therapeutic strategies.
Author: Lee Arnold Green
Publisher: Christian Faith Publishing, Inc.
ISBN:
Category : Religion
Languages : en
Pages : 532
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Book Description
The Book of Affinitive Life: Part 1 in Conjunction: The Book of Life is mainly about life on Earth concerning the invited signals of love that create addictions and eventually transcend into affinitive life. It is commonly characterized in the world as a passion, hobby, or bond to someone or something; and it is practiced or lived by means of a habitual lifestyle or habit by virtue of signal responsiveness in response to behavior in interaction with whom or what affinitive life centers on. The surprisingly interesting spiritual fact about the love signal is that it lies beyond ordinary experiences and supernaturally transcends into an acquired spirit that is grafted into your natural spirit as an integral part, which is then potentially lived as affinitive life, and in turn, a passion, hobby, or bond to someone or something. Affinitive life as a passion, hobby, or bond is actually unknown to the world as such. That is because it is spirit-based and all spiritual lives are physically based. First Corinthians 2:14-15 says, "The natural man receiveth not the things of the Spirit of God: for they are foolishness unto him: neither can he know them, because they are spiritually discerned. But he that is spiritual judgeth all things, yet he himself is judged of no man." That means scientists could never use genetic engineering to find the true meaning of passions, hobbies, or bonding to someone or something as an affinitive life because it is foolishness to them. Genetic engineering is the direct manipulation of an organism's genome, which means its genes are used by biotechnology, also called genetic modification, which is genetic manipulation of the genes of an organism's genome. This book is the book of affinitive life, part 1, to the natural side of life and the book of life to the spirit side of life of invited signals of love. For that reason, the name of this book is The Book of Affinitive Life: Part 1 in Conjunction: The Book of Life. It is called The Book of Affinitive Life as it refers to and relates to the natural side of life first, and then to the same degree, it relates to the spirit side of life. Additionally, it characterizes the Book of Life, which no natural or ordinary man could write; there had to be a spiritual component. All affinitive lives are lived optionally as a habitual lifestyle or habit in natural life, in conjunction with natural life as an integral part.
Author: Vladimir V. Klimov
Publisher: Springer Nature
ISBN: 303104309X
Category : Medical
Languages : en
Pages : 317
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Book Description
Allergies are a significant health issue, yet few books exist on allergen tolerance of separation; here the author classifies allergen tolerance breakdown in specific types, according to the possibility that the autonomic breakdown of allergen tolerance in the unified airway depends on a deficit of pro-tolerogenic neurotransmitters at the local level. This paradigm, which explains the pathogenesis of allergic disorders, opens to new approaches to allergen-specific immunotherapy (AIT). While focusing on the new atopic disorders of the unified airway, such as local allergic rhinitis, "dual" allergic rhinitis, local allergic asthma, and local allergic conjunctivitis, the work combines clinical examples of allergic diseases and their treatment with their immunological background. The topics range from the specific immune-derived maintenance of allergen tolerance and the role of the neuroimmune network in allergic inflammation to conventional atopic diseases and more particular issues of local atopic disorders in the unified airway, oral tolerance, and its breakdown, and its translation in genitourinary aspects of allergic inflammation. Specific chapters are also devoted to allergen-specific immunotherapy (AIT) and anti-allergy treatments. Thought for upper graduate students, it will also be a valued resource for allergy practitioners, pulmonologists, ENT specialists, pediatricians, and translational researchers. Textbook of Allergen Tolerance includes classical didactic features such as abstracts, keywords, background notes, discussion points, and Q&A., as well as 20 audio files Text-to-Speech for the visually impaired, and 10 video to support the readers.
Author: Neil Andrew Harrison
Publisher: Cambridge University Press
ISBN: 110842404X
Category : Medical
Languages : en
Pages : 357
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Book Description
The rapidly growing field of immunopsychiatry combines expertise and insights from immunology, psychiatry and neuroscience to understand the role of inflammation and other immune processes in causing and treating mental illness. This represents a major shift in mental health science, traditionally focused on psychological and neuronal mechanisms of depression, psychosis and dementia. This book provides the first comprehensive overview of recent, inter-disciplinary research linking disordered function of the immune system to the brain and mental illness. It offers a broad and deep perspective on the implications of immune system involvement in psychiatric disorders, including a balanced focus on basic science and clinical applications. Chapters cover the scientific evidence linking immune processes to major mental illnesses such as schizophrenia, depression, anxiety and dementia. An invaluable guide for graduate students, doctors in training, scientific researchers and others interested in the link between the immune system and mental health.
Author:
Publisher: Elsevier
ISBN: 0080559352
Category : Science
Languages : en
Pages : 609
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Book Description
This book opens a new page of neuro-immunobiology providing substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. The volume is a collection of complex, new data drawn from multiple areas of investigation in the field. The contents summarize current understanding on the presence and function of CNS cytokines and their receptors in a variety of CNS cells during health and disease. The chapters are a collection of complex, new data demonstrating the presence and synthesis of cytokines in brain cells, as well as their receptors on cell membranes in health and disease. The strength of the volume are the descriptions of the authors own investigations, together with those of others in the field pertaining to a large number of cytokines in brain function, as well as mechanisms involved in the development of CNS disorders, including multiple sclerosis and Alzheimer's disease. Also included are novel approaches to the treatment of CNS disorders based on new experimental data. The contributors to this volume are internationally known scientists and clinical researchers in their respective fields of investigation and treatment.*Opens a new page of neuro-immunobiology and provides substantive evidence for the promise of this field in the treatment of disease*Summarizes current understanding on the presence and function of central nervous system (CNS) cytokines and their receptors in a variety of CNS cells during health and disease*Includes novel approaches to the treatment of CNS disorders based on new experimental data*Offers new insight into triggers for the development of autoimmune diseases in the brain and the possibilities for treatment
Author: Sana Loue
Publisher: Springer Nature
ISBN: 3031103300
Category : Psychology
Languages : en
Pages : 370
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Book Description
This book responds to the needs that arise at the intersection of people and animals, focusing on human-animal interaction, human-animal studies, the emotional work of caring for animals, and animal-assisted interventions and therapies. Unlike many works that focus primarily on issues at the micro level, such as animal-assisted interventions, this volume is unique in its focus on issues arising at the micro, macro, and mezzo levels, encompassing human-animal issues and interactions at the level of individuals and family, groups, institutions, and communities. Accordingly, this comprehensive guide addresses the need to better prepare practitioners to work in interdisciplinary environments, whether in the context of theory, research, practice, or advocacy. The authorship of the volume reflects the interdisciplinary foundations of veterinary social work, with contributions from social workers, psychologists, veterinarians, physicians, anthropologists, and bioethicists. The volume is divided into five parts that examine, respectively: the foundations (history and scope) of veterinary social work (Part I); the practice of veterinary social work with individuals, in the context of community programs, and in social work practice (Part II); veterinary social work and the veterinary setting, including veterinary well-being and conflict management (Part III); veterinary social work education (Part IV); and the future of veterinary social work (Part V). Importantly, the volume addresses not only practice issues in the veterinary, clinical, and community settings, but also examines ethical concerns in the clinical and research contexts and the implications of cultural and societal variations on the practice of veterinary social work. The Comprehensive Guide to Interdisciplinary Veterinary Social Work is the definitive resource for social workers and psychologists new to practice issues relating to animals, social work and psychology students at the graduate and undergraduate levels, veterinarians and veterinary students, hospital administrators (human hospitals), and veterinary hospital managers.
Author: Golam Khandaker
Publisher: Cambridge University Press
ISBN: 1009038362
Category : Medical
Languages : en
Pages : 357
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Book Description
The rapidly growing field of immunopsychiatry combines expertise and insights from immunology, psychiatry and neuroscience to understand the role of inflammation and other immune processes in causing and treating mental illness. This represents a major shift in mental health science, traditionally focused on psychological and neuronal mechanisms of depression, psychosis and dementia. This book provides the first comprehensive overview of recent, inter-disciplinary research linking disordered function of the immune system to the brain and mental illness. It offers a broad and deep perspective on the implications of immune system involvement in psychiatric disorders, including a balanced focus on basic science and clinical applications. Chapters cover the scientific evidence linking immune processes to major mental illnesses such as schizophrenia, depression, anxiety and dementia. An invaluable guide for graduate students, doctors in training, scientific researchers and others interested in the link between the immune system and mental health.
Author: Allan Siegel
Publisher: Springer Science & Business Media
ISBN: 0387848517
Category : Medical
Languages : en
Pages : 437
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Book Description
For many years, the immune and central nervous systems were thought to function independently with little or no interaction between the two. This view has und- gone dramatic changes over the past three decades. Indeed, we now know that there exists various feedback loops between the brain and immune systems that impact signi cantly upon different behavioral processes, including normal behavior and mental disorders. Pioneering efforts in generating this change were initiated by a number of early investigators. Included were those whose efforts were directed at establishing neuroimmune connections as well as others whose research focused upon the relationship between immunity, cytokines, and behavior. This book brings together outstanding scientists and clinicians who have made major contributions to the rapidly developing eld investigating the relationship between immunity and behavior. The book is divided into three parts. The rst part describes pathways by which the brain and immune systems communicate and int- act with each other. In the chapter “Cytokines and the Blood–Brain Barrier” p- vides insight into interactions between the blood–brain barrier and cytokines. Such interactions underlie basic communication between the immune system and brain that are present in normal as well as in disease conditions. In the chapter “Neu- chemical and Endocrine Responses to Immune Activation: The Role of Cytokines,” the neurochemical and endocrine consequences of immune challenge and cytokine administration on central neurotransmitter activity are discussed.
