Hypothalamic Integration of Energy Metabolism PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Hypothalamic Integration of Energy Metabolism PDF full book. Access full book title Hypothalamic Integration of Energy Metabolism by A. Kalsbeek. Download full books in PDF and EPUB format.
Author: A. Kalsbeek
Publisher: Elsevier
ISBN: 0080463487
Category : Science
Languages : en
Pages : 431
Get Book Here
Book Description
The prevalence of obesity in developed countries is fast becoming a health issue on par with infectious diseases and malnutrition. Research in this area has grown substantially and includes the neurochemical pathways of the hypothalamus and its role in regulating energy expenditures in the body. This volume in the Progress in Brain Research series examines the emerging role of the hypothalamus as a crucial link between the sensing of nutrients and the control of insulin sensitivity, glucose uptake, and glucose production, the integrative role of the hypothalamus in thyroid and bone metabolism, the interaction between circadian information and energy metabolism, and the important interplay between the immune system and energy metabolism.· All contributors are recognized experts in their respective specialities· Provides expanded coverage of hypothalamic mechanisms involved in energy metabolism· Includes many outstanding full-colour illustrations· Contains special sections on circadian rhythms, immune system, thyroid and bone metabolism
Author: A. Kalsbeek
Publisher: Elsevier
ISBN: 0080463487
Category : Science
Languages : en
Pages : 431
Get Book Here
Book Description
The prevalence of obesity in developed countries is fast becoming a health issue on par with infectious diseases and malnutrition. Research in this area has grown substantially and includes the neurochemical pathways of the hypothalamus and its role in regulating energy expenditures in the body. This volume in the Progress in Brain Research series examines the emerging role of the hypothalamus as a crucial link between the sensing of nutrients and the control of insulin sensitivity, glucose uptake, and glucose production, the integrative role of the hypothalamus in thyroid and bone metabolism, the interaction between circadian information and energy metabolism, and the important interplay between the immune system and energy metabolism.· All contributors are recognized experts in their respective specialities· Provides expanded coverage of hypothalamic mechanisms involved in energy metabolism· Includes many outstanding full-colour illustrations· Contains special sections on circadian rhythms, immune system, thyroid and bone metabolism
Author:
Publisher:
ISBN:
Category : Energy metabolism
Languages : en
Pages : 413
Get Book Here
Book Description
Author: Jean-Pierre Montmayeur
Publisher: CRC Press
ISBN: 1420067761
Category : Medical
Languages : en
Pages : 646
Get Book Here
Book Description
Presents the State-of-the-Art in Fat Taste TransductionA bite of cheese, a few potato chips, a delectable piece of bacon - a small taste of high-fat foods often draws you back for more. But why are fatty foods so appealing? Why do we crave them? Fat Detection: Taste, Texture, and Post Ingestive Effects covers the many factors responsible for the se
Author: E. I. Sokolov
Publisher: VSP
ISBN: 9789067642125
Category : Medical
Languages : en
Pages : 338
Get Book Here
Book Description
This book is the result of the study of metabolic and hormonal disorders in patients suffering obesity and diabetes mellitus, focusing on mechanisms of formation of atherosclerotic changes in the myocardium and vessels in diabetes mellitus patient.
Author: Serge H. Luquet
Publisher: Frontiers Media SA
ISBN: 2889632024
Category :
Languages : en
Pages : 397
Get Book Here
Book Description
The hypothalamus plays a crucial role in the regulation of food intake and energy homeostasis. Hypothalamic neuronal circuits thus represent a privileged target for the treatment of eating disorders and metabolic diseases. The present eBook constitutes a unique collection of research articles and reviews that highlight new concepts and recent findings about the neuroendocrine control of feeding behavior.
Author: Frank P. Brooks
Publisher:
ISBN:
Category : Endocrine glands
Languages : en
Pages : 416
Get Book Here
Book Description
Author: Maria Moreno
Publisher: Frontiers Media SA
ISBN: 2889198855
Category : Physiology
Languages : en
Pages : 119
Get Book Here
Book Description
Alteration in adequate energy balance maintenance results in serious disturbances such as obesity and its related metabolic disorders. In Mammals, energy balance is homeostatically controlled through hormonal and neuroendocrine systems which cooperation is based on cross-talk between central and peripheral signals. The hypothalamus as well as peripheral hormones among which adipokines from adipose tissue and thyroid hormones play a crucial role in energy homeostasis. Unraveling the physiological, cellular and molecular mechanisms through which hormonal and neuroendocrine systems regulate energy balance has been a long-standing challenge in biology and is now more necessary when considering the world-wide increasing prevalence of obesity. Indeed, recognizing and understanding the biochemical and nutrient signaling pathways contributing to the nervous and endocrine integration of physiological mechanisms involved in the normal and/or abnormal regulation of energy balance is fundamental also to the development of new, effective, and targeted treatments for obesity. Recent studies have highlighted the role of hypothalamic pro-opiomelanocortin-expressing neurons in the regulation of energy homeostasis by controlling energy expenditure and food intake. This is accomplished through a precise balance of production and degradation of a-melanocyte-stimulating hormone, an anorexigenic neuropeptide which is degraded to an inactive form unable to inhibit food intake by the key enzyme prolyl carboxypeptidase (PRCP), thus suggesting that pharmacologic approaches targeting PRCP may provide a novel and effective option for the management of obesity and its associated metabolic disorders. Indeed, efforts have been made to generate potent, brain-penetrant PRCP inhibitors. Weight loss due to negative energy balance is a goal for obese subjects not always reachable by dietary caloric restriction or increased physical activity. Lipid-lowering therapies have been suggested to have potential benefits, however, the establishment of comprehensive therapeutic strategies is still awaited. Recently, it has been reported that thyroid hormone (TH)- derivatives such as 3,5-diiodothyronine and 3-iodothyronamine possess interesting biological activities, opening new perspectives in thyroid physiology and TH derivatives therapeutic usage. Moreover, several studies, focusing on the interaction between thyroid hormone (TH), the autonomic nervous system and the liver, revealed an important role for the hypothalamus in the differential effects of TH on autonomic outflow to peripheral organs controlling energy balance. This Research Topic aims to give a comprehensive and integrate view of the factors involved in the endocrine and neuroendocrine signaling in energy balance regulation to highlight their involvement into physiological processes and regulatory systems as well as their perturbation during pathological processes.
Author: Roger D. Cone
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 416
Get Book Here
Book Description
In the decade before the publication of this study, melanocortin biology matured. Three additional receptors were discovered, and animal models were established addressing the function of each receptor. Researchers now know that the diverse physiologic responses to melanocortins - including their role in development, weight and endocrine regulation, cortisol production, secretion from exocrine glands, and pigmentation - can be defined in terms of individual receptors. In this text, contributors from the field of evolutionary biology, peptide chemistry, pigmentation biology, neuroscience, endocrinology and genetics provide the reader with a comprehensive review of melanocortin biology. Six areas of active research are addressed: peptide and small molecule chemistry; receptor structure and function; energy homeostasis; pigmentation; adrenocorticol function; and behaviour. There are 56 papers and 20 posters altogether, taken from the Fifth Melanocortin Meeting, held in 2002.
Author: Claude Kordon
Publisher: Springer Science & Business Media
ISBN: 3642189997
Category : Medical
Languages : en
Pages : 200
Get Book Here
Book Description
In mammals, a robust physiologic system acts to maintain relative constancy of weight. A key element of this system is leptin. The nature of this "brain-somatic" cross talk is as yet poorly understood, but it is likely to have important implications for the pathophysiology and treatment of obesity, diabetes and other metabolic disorders.
Author: Bertalan Dudás
Publisher: Nova Biomedical Books
ISBN: 9781620818060
Category : Hypothalamus
Languages : en
Pages : 0
Get Book Here
Book Description
The hypothalamus is a particularly complex part of the brain; it represents only a fragment of the brain volume and yet it is considered as one the most important regions involved in maintaining homeostasis and in the resulting survival of the individual. Since most of the experimental data in the scientific literature are based on animal studies, there is an emerging need for a volume that provides a review of the current research and knowledge of the major hypothalamic functions in humans. This book is intended to tackle these functions and the ensuing morphological and pathological aspects in order to give the reader a cross section of the most recent data and major trends in the current hypothalamic research in a convenient, compact format.
