Human Cancer Markers

Human Cancer Markers PDF Author: Stewart Sell
Publisher: Springer Science & Business Media
ISBN: 1461258081
Category : Medical
Languages : en
Pages : 443

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Book Description
The ability to diagnose cancer by simple measurement of a serum or tissue' 'marker" has been a goal of medical science for many years. There is ample evidence that tumor cells are different from normal cells and pro duce substances that can be detected by currently available immuno chemical or biochemical methods. These "cancer markers" may be se creted proteins, enzymes, hormones, fetal serum components, monoclonal immunoglobulins, cell surface components, or cytoplasmic constituents. The purpose of this book is to present the current status of our knowledge of such cancer markers. The first tumor marker identified by laboratory means was Bence Jones protein. In a series of lectures delivered to the Royal College of Phy sicians in London in 1846, Dr. H. Bence Jones described studies on a urine sample sent to him with the following note: "Dear Dr. Jones-The tube contains urine of very high specific gravity. When boiled it becomes slightly opaque . . . . etc. " Dr. Jones found that heating of the urine after addition of nitric acid resulted in formation of a heavy precipitate; acid ad dition may have been required to bring the urine to pH 4-6 at which Bence Jones proteins are more likely to precipitate when heated. This urinary pre cipitate was associated with a bone disease termed "mollities ossium. " [H. Bence Jones, Papers on Chemical Pathology, Lecture III. Lancet 2, 269-274 (1847)].

Human Cancer Markers

Human Cancer Markers PDF Author: Stewart Sell
Publisher: Springer Science & Business Media
ISBN: 1461258081
Category : Medical
Languages : en
Pages : 443

Get Book Here

Book Description
The ability to diagnose cancer by simple measurement of a serum or tissue' 'marker" has been a goal of medical science for many years. There is ample evidence that tumor cells are different from normal cells and pro duce substances that can be detected by currently available immuno chemical or biochemical methods. These "cancer markers" may be se creted proteins, enzymes, hormones, fetal serum components, monoclonal immunoglobulins, cell surface components, or cytoplasmic constituents. The purpose of this book is to present the current status of our knowledge of such cancer markers. The first tumor marker identified by laboratory means was Bence Jones protein. In a series of lectures delivered to the Royal College of Phy sicians in London in 1846, Dr. H. Bence Jones described studies on a urine sample sent to him with the following note: "Dear Dr. Jones-The tube contains urine of very high specific gravity. When boiled it becomes slightly opaque . . . . etc. " Dr. Jones found that heating of the urine after addition of nitric acid resulted in formation of a heavy precipitate; acid ad dition may have been required to bring the urine to pH 4-6 at which Bence Jones proteins are more likely to precipitate when heated. This urinary pre cipitate was associated with a bone disease termed "mollities ossium. " [H. Bence Jones, Papers on Chemical Pathology, Lecture III. Lancet 2, 269-274 (1847)].

Human Cytogenetic Cancer Markers

Human Cytogenetic Cancer Markers PDF Author: Sandra R. Wolman
Publisher: Springer Science & Business Media
ISBN: 1461239524
Category : Medical
Languages : en
Pages : 491

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Book Description
Seventeen cutting-edge chapters review both basic research and clinical applications of chromosomal markers of cancer. The new markers offer great promise, not only for their clinical utility in diagnosis, prognosis, and disease monitoring, but also for their contributions to a better understanding of the mechanisms of tumor development and progression. The chapters-all written by leading authorities-skillfully reveal fresh insights into the translational role of cytogenetics in identifying the cellular and molecular changes that occur in cancer. Coverage is devoted to many tissue systems-colon, breast, prostate, lung, skin, brain, and kidney-where the diagnostic and prognostic utility of chromosome markers is clearly demonstrated. A seminal book certain to become the front-line reference and authoritative resource needed by all scientists and clinicians engaged in cancer research, diagnosis, and management.

Cellular Cancer Markers

Cellular Cancer Markers PDF Author: Carleton T. Garrett
Publisher: Springer Science & Business Media
ISBN: 1475723814
Category : Medical
Languages : en
Pages : 491

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Book Description
In Cellular Cancer Markers leading pathologists and physicians review today's most promising cellular cancer markers, an important emerging class of prognostic markers that can be used in the clinical evaluation of cancer patients. The markers reviewed have been chosen because they are biologically relevant to the growth of cells and possess an accurate and reproducible assay for detection. They also are predictors of tumor behavior, are useful in making clinical decisions, and are cost effective. Cellular Cancer Markers provides a status report for markers of tumor cell activation, proliferation, and longevity that makes possible an informed judgment regarding the value of many newly proposed tumor markers. It also offers insight into the latest approaches to diagnosing cancer and an appreciation of how these marker-based tests can clarify the prognosis of cancer.

Human Tumor Markers

Human Tumor Markers PDF Author: F. Cimino
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110846519
Category : Science
Languages : en
Pages : 940

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Book Description
No detailed description available for "Human Tumor Markers".

Tumor Markers

Tumor Markers PDF Author: Eleftherios P. Diamandis
Publisher: Amer. Assoc. for Clinical Chemistry
ISBN: 9781890883713
Category : Medical
Languages : en
Pages : 584

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Book Description


Cancer and Pregnancy

Cancer and Pregnancy PDF Author: Eytan R. Barnea
Publisher: Springer Science & Business Media
ISBN: 1447107071
Category : Medical
Languages : en
Pages : 316

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Book Description
Cancer and Pregnancy covers the clinical challenges to diagnosing and treating malignancies in the pregnant patient; however, the book also shows how an understanding of the common features of both processes (rapid cell proliferation) may lead to novel anti-cancer treatment options. The book should be read by obstetricians and gynaecologists, clinical oncologists, reproduction specialists, and those involved in investigation of development, biology, toxicology, immunology, as well as cancer research.

Program and abstracts from the 5th International Conference on Human Tumor Markers

Program and abstracts from the 5th International Conference on Human Tumor Markers PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 35

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Book Description


Markers of Chemically Induced Cancer

Markers of Chemically Induced Cancer PDF Author: Gustave Freeman
Publisher: William Andrew
ISBN:
Category : Cancer
Languages : en
Pages : 264

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Book Description


Human Tumor Markers, Biological Basis and Clinical Relevance

Human Tumor Markers, Biological Basis and Clinical Relevance PDF Author: Herbert E. Nieburgs
Publisher:
ISBN: 9780845102282
Category : Cancer
Languages : en
Pages : 337

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Book Description


Tumor Markers

Tumor Markers PDF Author: Nasser Javadpour
Publisher: Praeger
ISBN:
Category : Health & Fitness
Languages : en
Pages : 312

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Book Description
Tumor markers, or antigens, are subtances produced in the body by malignant tumors. Their detection is useful in both diagnosing cancer and monitoring therapy. This straight-forward book provides a comprehensive overview designed to assist physicians who deal with cancer patients. The contributions by leading authorities include discussions of techniques for detecting tumor markers, steroid receptors, monoclonal antibodies, flow cytometry, chromosomal abnormalities, radioimmunodetection, ectopic hormones, cell markers in leukemia, nucleolar antigens, and non-specific markers.