HISTOIRE NATURELLE DU CANCER DU SEIN, APPROCHE BIOMATHEMATIQUE

HISTOIRE NATURELLE DU CANCER DU SEIN, APPROCHE BIOMATHEMATIQUE PDF Author: SERGE.. KOSCIELNY
Publisher:
ISBN:
Category :
Languages : fr
Pages :

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Book Description
CE TRAVAIL EST BASE SUR L'ETUDE D'UNE POPULATION DE FEMMES TRAITEES POUR DES CANCERS DU SEIN A L'INSTITUT GUSTAVE ROUSSY, A VILLEJUIF, ENTRE 1954 ET 1978. L'ANALYSE DE LA RELATION ENTRE LA PROBABILITE DE DISSEMINATION METASTATIQUE ET LA DIMENSION DES TUMEURS DU SEIN AU MOMENT DU TRAITEMENT INITIAL A ETE EFFECTUEE SANS FAIRE D'HYPOTHESE CONCERNANT LE MODE DE CROISSANCE TUMORALE. CETTE ETUDE FOURNIT UNE ESTIMATION INDIRECTE DE LA DISTRIBUTION DU VOLUME TUMORAL AU MOMENT DE L'INITIATION DES METASTASES DISTANTES (VOLUME SEUIL). LES DONNEES INDIQUENT QUE LE VOLUME SEUIL EST EN MOYENNE TRES PEU INFERIEUR A CELUI DE LA TUMEUR AU MOMENT DU DIAGNOSTIC. CE RESULTAT EST UTILISE POUR DEVELOPPER UN MODELE DE SIMULATION DE L'HISTOIRE NATURELLE DU CANCER DU SEIN, TENANT COMPTE DES DONNEES CLINIQUES. NOUS TROUVONS QUE LA DUREE DE CROISSANCE DES METASTASES EST ENVIRON DEUX FOIS PLUS COURTE QUE CELLE PREVUE PAR LES MODELES PRECEDENTS (18 TEMPS DE DOUBLEMENT AU LIEU DE 30). LE MODELE PREDIT QUE L'INCIDENCE DES METASTASES SERA REDUITE D'ENVIRON 30% SI LES TUMEURS PRIMITIVES SONT TRAITEES 12 MOIS PLUS TOT. CETTE PREDICTION EST EN ACCORD AVEC LES RESULTATS DES PROGRAMMES DE DEPISTAGE SYSTEMATIQUES DU CANCER DU SEIN. LA CHIMIOTHERAPIE ADJUVANTE EST ETUDIEE EN ESTIMANT LA DISTRIBUTION DE LA DIMENSION DES METASTASES OCCULTES AU MOMENT DU TRAITEMENT DE LA TUMEUR PRIMITIVE. L'ETUDE DE FACTEURS PRONOSTIQUES EST ILLUSTREE PAR UN MODELE BASE SUR L'HYPOTHESE D'UN ENVAHISSEMENT PROGRESSIF DES GANGLIONS AXILLAIRES. NOUS MONTRONS NOTAMMENT QUE LA SIGNIFICATION PRONOSTIQUE DE L'ENVAHISSEMENT AXILLAIRE PEUT ETRE PRECISEE EN TENANT COMPTE DE LA DIMENSION TUMORALE

HISTOIRE NATURELLE DU CANCER DU SEIN, APPROCHE BIOMATHEMATIQUE

HISTOIRE NATURELLE DU CANCER DU SEIN, APPROCHE BIOMATHEMATIQUE PDF Author: SERGE.. KOSCIELNY
Publisher:
ISBN:
Category :
Languages : fr
Pages :

Get Book Here

Book Description
CE TRAVAIL EST BASE SUR L'ETUDE D'UNE POPULATION DE FEMMES TRAITEES POUR DES CANCERS DU SEIN A L'INSTITUT GUSTAVE ROUSSY, A VILLEJUIF, ENTRE 1954 ET 1978. L'ANALYSE DE LA RELATION ENTRE LA PROBABILITE DE DISSEMINATION METASTATIQUE ET LA DIMENSION DES TUMEURS DU SEIN AU MOMENT DU TRAITEMENT INITIAL A ETE EFFECTUEE SANS FAIRE D'HYPOTHESE CONCERNANT LE MODE DE CROISSANCE TUMORALE. CETTE ETUDE FOURNIT UNE ESTIMATION INDIRECTE DE LA DISTRIBUTION DU VOLUME TUMORAL AU MOMENT DE L'INITIATION DES METASTASES DISTANTES (VOLUME SEUIL). LES DONNEES INDIQUENT QUE LE VOLUME SEUIL EST EN MOYENNE TRES PEU INFERIEUR A CELUI DE LA TUMEUR AU MOMENT DU DIAGNOSTIC. CE RESULTAT EST UTILISE POUR DEVELOPPER UN MODELE DE SIMULATION DE L'HISTOIRE NATURELLE DU CANCER DU SEIN, TENANT COMPTE DES DONNEES CLINIQUES. NOUS TROUVONS QUE LA DUREE DE CROISSANCE DES METASTASES EST ENVIRON DEUX FOIS PLUS COURTE QUE CELLE PREVUE PAR LES MODELES PRECEDENTS (18 TEMPS DE DOUBLEMENT AU LIEU DE 30). LE MODELE PREDIT QUE L'INCIDENCE DES METASTASES SERA REDUITE D'ENVIRON 30% SI LES TUMEURS PRIMITIVES SONT TRAITEES 12 MOIS PLUS TOT. CETTE PREDICTION EST EN ACCORD AVEC LES RESULTATS DES PROGRAMMES DE DEPISTAGE SYSTEMATIQUES DU CANCER DU SEIN. LA CHIMIOTHERAPIE ADJUVANTE EST ETUDIEE EN ESTIMANT LA DISTRIBUTION DE LA DIMENSION DES METASTASES OCCULTES AU MOMENT DU TRAITEMENT DE LA TUMEUR PRIMITIVE. L'ETUDE DE FACTEURS PRONOSTIQUES EST ILLUSTREE PAR UN MODELE BASE SUR L'HYPOTHESE D'UN ENVAHISSEMENT PROGRESSIF DES GANGLIONS AXILLAIRES. NOUS MONTRONS NOTAMMENT QUE LA SIGNIFICATION PRONOSTIQUE DE L'ENVAHISSEMENT AXILLAIRE PEUT ETRE PRECISEE EN TENANT COMPTE DE LA DIMENSION TUMORALE

Geometric and Computational Spectral Theory

Geometric and Computational Spectral Theory PDF Author: Alexandre Girouard
Publisher: American Mathematical Soc.
ISBN: 147042665X
Category : Mathematics
Languages : en
Pages : 298

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Book Description
A co-publication of the AMS and Centre de Recherches Mathématiques The book is a collection of lecture notes and survey papers based on the mini-courses given by leading experts at the 2015 Séminaire de Mathématiques Supérieures on Geometric and Computational Spectral Theory, held from June 15–26, 2015, at the Centre de Recherches Mathématiques, Université de Montréal, Montréal, Quebec, Canada. The volume covers a broad variety of topics in spectral theory, highlighting its connections to differential geometry, mathematical physics and numerical analysis, bringing together the theoretical and computational approaches to spectral theory, and emphasizing the interplay between the two.

Medical Computer Vision

Medical Computer Vision PDF Author: Bjoern Menze
Publisher: Springer
ISBN: 3642184219
Category : Computers
Languages : en
Pages : 235

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Book Description
This book constitutes the thoroughly refereed post-workshop proceedings of the International Workshop on Medical Computer Vision, MCV 2010, held in Beijing, China, in September 2010 as a satellite event of the 13th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2010. The 10 revised full papers and 11 revised poster papers presented were carefully reviewed and selected from 38 initial submissions. The papers explore the use of modern image recognition technology in tasks such as semantic anatomy parsing, automatic segmentation and quantification, anomaly detection and categorization, data harvesting, semantic navigation and visualization, data organization and clustering, and general-purpose automatic understanding of medical images.

Women in England, 1870-1950

Women in England, 1870-1950 PDF Author: Jane E. Lewis
Publisher: Brighton, Sussex : Wheatsheaf Books ; Bloomington : Indiana University Press
ISBN:
Category : Family & Relationships
Languages : en
Pages : 264

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Book Description
"... offers an alternative depth of context for viewing the structure of women's lives.... thoughtful and judicious." --Joyce Berkman "Women in England breaks ground in its interpretive treatment of feminist, suffrage, and labor issues in a single volume." --Signs A penetrating account of the changing nature of English working and middle-class women's experiences at school, home, work, and in politics from 1870 to 1950.

Connecting Spheres

Connecting Spheres PDF Author: Marilyn J. Boxer
Publisher: Oxford University Press, USA
ISBN: 9780195041330
Category : History
Languages : en
Pages : 308

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Book Description
Integrating the discoveries of the new feminist scholarship with the main themes of Western civilization, this text examines women's influence on, and daily connections with, the religious, political, economic, scientific, social, and cultural changes that have transformed our world during the last half-millennium.

Global Solutions of Reaction-Diffusion Systems

Global Solutions of Reaction-Diffusion Systems PDF Author: Franz Rothe
Publisher: Springer
ISBN: 3540389172
Category : Science
Languages : en
Pages : 222

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Book Description


Food Fray

Food Fray PDF Author: Lisa H. WEASEL Ph.D.
Publisher: AMACOM Div American Mgmt Assn
ISBN: 0814401783
Category : Technology & Engineering
Languages : en
Pages : 258

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Book Description
More than ten years ago, the first genetically modified foods took their place on the shelves of American supermarkets. But while American consumers remained blissfully unconcerned with the new products that suddenly filled their kitchens, Europeans were much more wary of these “Frankenfoods.” When famine struck Africa in 2002, several nations refused shipments of genetically modified foods, fueling a controversy that put the issue on the world's political agenda for good. In Food Fray, esteemed molecular biologist Dr. Lisa H. Weasel brings readers into the center of this debate, capturing the real-life experiences of the scientists, farmers, policymakers and grassroots activists on the front lines. Here she combines solid scientific knowledge and a gripping narrative to tell the real story behind the headlines and the hype. Seminal and cutting-edge, Food Fray enlightens and informs and will allow readers to make up their own minds about one of the most important issues facing us today.

Almost-periodic Functions in Abstract Spaces

Almost-periodic Functions in Abstract Spaces PDF Author: Samuel Zaidman
Publisher: Pitman Advanced Publishing Program
ISBN:
Category : Mathematics
Languages : en
Pages : 148

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Book Description
This research not presents recent results in the field of almost-periodicity. The emphasis is on the study of vector-valued almost-periodic functions and related classes, such as asymptotically almost-periodic or almost-automorphic functions. Many examples are given, and applications are indicated. The first three chapters form a self-contained introduction to the study of continuity, derivability and integration in locally convex or Banach spaces. The remainder of the book is devoted to almost-periodicity and related topics. The functions are defined on IR, IR[superscript n] or an abstract group; the range is a Banach or a Hilbert space. Although treatment of the material related to pure mathematics, the theory has many applications in the area of abstract differential equations.

Women's History

Women's History PDF Author: June Purvis
Publisher: Psychology Press
ISBN: 0415238897
Category : History
Languages : en
Pages : 341

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Book Description
Women's History: Britain 1850-1945 introduces the main themes and debates of feminist history during this period of change, and brings together the findings of new research. It examines the suffrage movement, race and empire, industrialisation, the impact of war and womens literature. Specialists in their own fields have each written a chapter on a key aspect of womens lives including health, the family, education, sexuality, work and politics. Each contribution provides an overview of the main issues and debates within each area and offers suggestions for further reading. It not only provides an invaluable introduction to every aspect of womens participation in the political, social and economic history of Britain, but also brings the reader up to date with current historical thinking on the study of womens history itself.

Parabolic Equations in Biology

Parabolic Equations in Biology PDF Author: Benoît Perthame
Publisher: Springer
ISBN: 331919500X
Category : Mathematics
Languages : en
Pages : 204

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Book Description
This book presents several fundamental questions in mathematical biology such as Turing instability, pattern formation, reaction-diffusion systems, invasion waves and Fokker-Planck equations. These are classical modeling tools for mathematical biology with applications to ecology and population dynamics, the neurosciences, enzymatic reactions, chemotaxis, invasion waves etc. The book presents these aspects from a mathematical perspective, with the aim of identifying those qualitative properties of the models that are relevant for biological applications. To do so, it uncovers the mechanisms at work behind Turing instability, pattern formation and invasion waves. This involves several mathematical tools, such as stability and instability analysis, blow-up in finite time, asymptotic methods and relative entropy properties. Given the content presented, the book is well suited as a textbook for master-level coursework.