Author: Yoshitsugu Tajima
Publisher: Springer Science & Business Media
ISBN: 4431877738
Category : Medical
Languages : en
Pages : 244
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Book Description
Malignant neoplasms occurring in the biliary tract and pancreas remain a therap- tic challenge. The mechanism of carcinogenesis as well as the growth and spread of these tumors is still poorly understood, making the development of rational tre- ment strategies difficult. In order to improve the clinical results achieved by sur- cal or other medical treatment of such malignant tumors, the establishment of an experimental animal model is critical. For this purpose, attempts were made to induce carcinoma experimentally in the biliary tree and finally an animal model using the hamster was established in 1994 at our laboratory. Because the tumor in this model mimicked the characteristics of human tumors, a series of experimental investigations were conducted to clarify the pathological characteristics of biliary carcinoma, the genetic alterations during biliary carcinogenesis, and the relationship between biliary inflammation and c- cinogenesis. The chemopreventive effects on the occurrence of biliary carcinoma were also successfully examined. In addition, in vitro studies led to the establi- ment of transplantable biliary cancer cell lines and biliary epithelial cell lines by utilizing the hamster model. This monograph represents the collective efforts in hepato-biliary and pancreatic disease research over the past 20 years. I hope that this monograph will be a source of useful knowledge for basic researchers as well as for clinicians involved in the care of patients with hepato-biliary and pancreatic neoplasms. Takashi Kanematsu, M.D., Ph.D.
Author: Takuji Tanaka
Publisher: MDPI
ISBN: 3038426083
Category : Medical
Languages : en
Pages : 257
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This book is a printed edition of the Special Issue "Inflammation and Cancer" that was published in IJMS
Author:
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ISBN:
Category : Cancer
Languages : en
Pages : 836
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Author:
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ISBN:
Category : Medicine
Languages : en
Pages : 1840
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Author: 小柳泰久,青木達哉
Publisher: 医学図書出版株式会社
ISBN: 9784871513173
Category :
Languages : en
Pages : 444
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Book Description
Author: Mark A. Suckow
Publisher: Academic Press
ISBN: 0123809207
Category : Medical
Languages : en
Pages : 1289
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Book Description
This is a single volume, comprehensive book sanctioned by the American College of Laboratory Animal Medicine (ACLAM), covering the rabbit, guinea pig, hamster, gerbil and other rodents often used in research. This well illustrated reference includes basic biology, anatomy, physiology, behavior, infectious and noninfectious diseases, husbandry and breeding, common experimental methods, and use of the species as a research model. It is a resource for advancements in the humane and responsible care of: rabbit, guinea pig, hamster, gerbil, chinchilla, deer mouse, kangaroo rat, cotton rat, sand rat, and degu Includes up-to-date, common experimental methods. Organized by species for easy access during bench research.
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ISBN:
Category : Medicine
Languages : en
Pages : 742
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ISBN:
Category : Toxicology
Languages : en
Pages : 624
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ISBN:
Category : Cancer
Languages : en
Pages : 716
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Book Description
Current information about research grants and contracts supported by the National Cancer Institute. Subject listing gives contract or grant number and topic. Investigator, grant number, and contract number indexes.
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ISBN:
Category : Cancer
Languages : en
Pages : 714
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