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Author: Orla Hardiman
Publisher: Springer
ISBN: 3319233092
Category : Medical
Languages : en
Pages : 335
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Book Description
This new edition provides an accessible guide to the commonest neurodegenerative diseases, outlining the main clinical features, treatment options and outcomes of the conditions most frequently encountered in clinical practice. Beginning with an overview of the general principles that underlie degeneration, and the contribution of established and new diagnostics techniques, the book goes on to describe the most common neurodegenerative conditions and, new for the second edition, also HIV dementia and multiple sclerosis. Final chapters cover important management issues including the use of palliative care strategies, biomarkers and neuropsychology. Written by experts in the field internationally Neurodegenerative Disorders, Second Edition is a practical guide for clinicians that will be indispensable for the management of these conditions.
Author: Orla Hardiman
Publisher: Springer
ISBN: 3319233092
Category : Medical
Languages : en
Pages : 335
Get Book Here
Book Description
This new edition provides an accessible guide to the commonest neurodegenerative diseases, outlining the main clinical features, treatment options and outcomes of the conditions most frequently encountered in clinical practice. Beginning with an overview of the general principles that underlie degeneration, and the contribution of established and new diagnostics techniques, the book goes on to describe the most common neurodegenerative conditions and, new for the second edition, also HIV dementia and multiple sclerosis. Final chapters cover important management issues including the use of palliative care strategies, biomarkers and neuropsychology. Written by experts in the field internationally Neurodegenerative Disorders, Second Edition is a practical guide for clinicians that will be indispensable for the management of these conditions.
Author: R.J. Castellani
Publisher: IOS Press
ISBN: 164368065X
Category : Medical
Languages : en
Pages : 506
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Book Description
Holbourne’s theory that rotational head movement and shear strains were limiting factors in producing acute parenchymal brain damage was a watershed moment in understanding traumatic brain injury (TBI). Long term effects, and in particular neurodegenerative proteinopathy subsequent to TBI, remain theoretical, notwithstanding the poorly understood ‘punch drunk’ syndrome of the early and mid-20th century, and the 21st century concept of chronic traumatic encephalopathy. This book, the Handbook of Traumatic Brain Injury and Neurodegeneration, has as its theme the marriage between neurodegenerative disease and neurotrauma through TBI surrogates such as sport, military service, and experimental models, and the legitimacy of that marriage. In the 32 contributions included here, this handbook not only explores the deleterious effects of genuine TBI, but also, and more importantly, the relationship between TBI and neurodegeneration. Controversy notwithstanding, there is much to be learned about the biological effects of TBI, substrates for long-term sequelae, the relationship between TBI and diverse neuropsychiatric disorders, and targets for therapy. The overall message to the neuroscience community from these papers may be a cautionary tale. The null hypothesis, that there is no causal relationship between TBI and progressive neurodegenerative disease, appears to be very much in play, and the book will be of interest to all those working in the field.
Author: Gabor G. Kovacs
Publisher: Cambridge University Press
ISBN: 1316337650
Category : Medical
Languages : en
Pages : 320
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Book Description
This practical guide to the diagnosis of neurodegenerative diseases discusses modern molecular techniques, morphological classification, fundamentals of clinical symptomology, diagnostic pitfalls and immunostaining protocols. It is based on the proteinopathy concept of neurodegenerative disease, which has influenced classification and provides new strategies for therapy. Numerous high-quality images, including histopathology photomicrographs and neuroradiology scans, accompany the description of morphologic alterations and interpretation of immunoreactivities. Diagnostic methods and criteria are placed within recent developments in neuropathology, including the now widespread application of immunohistochemistry. To aid daily practice, the guide includes diagnostic algorithms and offers personal insights from experienced experts in the field. Special focus is given to the way brain tissue should be handled during diagnosis. This is a must-have reference for medical specialists and specialist medical trainees in the fields of pathology, neuropathology and neurology working with neuropathologic features of neurodegenerative diseases.
Author: Panagiotis Vlamos
Publisher: Springer Nature
ISBN: 3319759221
Category : Medical
Languages : en
Pages : 1031
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Book Description
The Handbook of Computational Neurodegeneration provides a comprehensive overview of the field and thus bridges the gap between standard textbooks of research on neurodegeneration and dispersed publications for specialists that have a narrowed focus on computational methods to study this complicated process. The handbook reviews the central issues and methodological approaches related to the field for which the reader pursues a thorough overview. It also conveys more advanced knowledge, thus serving both as an introductory text and as a starting point for an in-depth study of a specific area, as well as a quick reference source for the expert by reflecting the state of the art and future prospects. The book includes topics that are usually missing in standard textbooks and that are only marginally represented in the specific literature. The broad scope of this handbook is reflected by five major parts that facilitate an integration of computational concepts, methods and applications in the study of neurodegeneration. Each part is intended to stand on its own, giving an overview of the topic and the most important problems and approaches, which are supported by examples, practical applications, and proposed methodologies. The basic concepts and knowledge, standard procedures and methods are presented, as well as recent advances and new perspectives.
Author: Musthafa M Essa
Publisher: Springer
ISBN: 9789819975563
Category : Science
Languages : en
Pages : 0
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Book Description
This Handbook discusses the pathology, etiology, pathogenesis, and therapeutic interventions of different neurodegenerative diseases. The initial section of the Handbook reviews the recent advances in understanding neurodegenerative diseases and the commonalities and differences between the major pathologies. The subsequent section presents recent developments in understanding fundamental biological mechanisms that influence the onset and development of neurodegenerative diseases. It provides current biomedical studies that are aimed at identifying the underlying causes of neurodegeneration. The book also examines the recent observations from biological, cellular, and studies from the model organisms for gaining mechanistic insights into neurodegenerative disorders. It also presents the epidemiological and genetics studies relevant to clinical aspects of neurodegenerative diseases. The book's subsequent chapters offer new and more effective therapeutic strategies to combat these devastating diseases. Towards the end, the Handbook presents recent advances in molecular diagnostics for neurodegenerative disorders and a perspective on the future directions to provide a framework for further developments and refinements of molecular diagnostics to combat neurodegenerative diseases.
Author: David B. Vodusek
Publisher: Elsevier
ISBN: 0444632549
Category : Medical
Languages : en
Pages : 518
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Book Description
The neurology of sex and bladder disorders requires specialized knowledge and represents a challenge for clinical neurologists focused on the neurological condition. Sex and bladder disorders are often related to more general neurological disorders like Parkinson's disease and multiple sclerosis, and often the sex and bladder disorders are passed to specialists in urology. Neurology of Sexual and Bladder Disorders: Handbook of Clinical Neurology is a focused, yet comprehensive overview that provides complete tutorial reference to the science, diagnosis and treatment of sex and bladder disorders from a neurologic perspective. - Comprehensive coverage of the neurology of sex and bladder disorders - Details the latest techniques for the study, diagnosis and treatment of sex and bladder dysfunction from a neurological perspective - A focused reference for clinical practitioners and neurology research communities
Author: Kewal K. Jain
Publisher: Humana
ISBN: 9781493994670
Category : Medical
Languages : en
Pages : 0
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Book Description
This fully revised edition explores the management of neurological disorders with a focus on neuroprotection, disease modification, and neuroregeneration rather than symptomatic treatment. Since the publication of the first edition, advances in biotechnology, particularly in cell and gene therapies, are reflected in this volume, as are numerous new and repurposed drugs in clinical trials. Overall, The Handbook of Neuroprotection serves as a comprehensive review of neuroprotection based on knowledge of the molecular basis of disorders of the central nervous system. In-depth and authoritative, The Handbook of Neuroprotection, Second Edition features a compendium of vital knowledge aimed at providing researchers with an essential reference for this key neurological area of study.
Author:
Publisher: Elsevier
ISBN: 0444636420
Category : Medical
Languages : en
Pages : 448
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Book Description
Brain Banking, Volume 150, serves as the only book on the market offering comprehensive coverage of the functional realities of brain banking. It focuses on brain donor recruitment strategies, brain bank networks, ethical issues, brain dissection/tissue processing/tissue dissemination, neuropathological diagnosis, brain donor data, and techniques in brain tissue analysis. In accordance with massive initiatives, such as BRAIN and the EU Human Brain Project, abnormalities and potential therapeutic targets of neurological and psychiatric disorders need to be validated in human brain tissue, thus requiring substantial numbers of well characterized human brains of high tissue quality with neurological and psychiatric diseases. - Offers comprehensive coverage of the functional realities of brain banking, with a focus on brain donor recruitment strategies, brain bank networks, ethical issues, and more - Serves as a valuable resource for staff in existing brain banks by highlighting best practices - Enhances the sharing of expertise between existing banks and highlights a range of techniques applicable to banked tissue for neuroscience researchers - Authored by leaders from brain banks around the globe – the broadest, most expert coverage available
Author: Dick F. Swaab
Publisher: Elsevier
ISBN: 0128199741
Category : Science
Languages : en
Pages : 520
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Book Description
The Human Hypothalamus: Neuropsychiatric Disorders, Volume 181 in the Handbook of Clinical Neurology series, provides comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. This volume identifies the neurobiology and neurophysiology of disorders relating to the hypothalamus and provides treatment information for these disorders. Disorders covered include neuropsychiatric, neurodegenerative, periodic, and autoimmune disorders. Coverage includes Alzheimer's, Parkinson's, epilepsy, sleep, pain, depression, anxiety, OCD, PTSD, schizophrenia, autism, aggressions, addiction, and more. - Summarizes research on how the hypothalamus relates to neurological disorders - Contains neuropsychiatric, neurodegenerative, periodic and autonomic disorders - Includes the neurobiology of, and treatment for, each disorder - Covers depression, anxiety, OCD, PTSD, schizophrenia, autism, aggression, addiction, and more - Provides coverage of sleep and pain
Author:
Publisher: Academic Press
ISBN: 0128026154
Category : Medical
Languages : en
Pages : 640
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Book Description
Neuropathology, Volume 145, the latest release in the Handbook of Clinical Neurology series, includes all the major topics found in a typical neuropathology text, but differentiates itself by providing a thorough overview of the morphological background of neurological disorders for researchers and clinicians who do not specialize in pathology or its clinicopathological aspects. This volume offers strong coverage of brain imaging and advances in molecular pathology and genetics, and is particularly timely given the amount of neuropathological research currently taking place. - Provides a resource for the non-pathologist, aiding primary clinicians and researchers in the interpretation of patient symptoms and research findings - Includes standard neuropathology, but extends to clinicopathology, imaging and molecular pathology/genetics - Presents an interdisciplinary approach that can be applied in everyday clinic and research efforts
