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Author: Robert Helms
Publisher: Garrett County Press
ISBN: 1891053280
Category : Biography & Autobiography
Languages : en
Pages : 270
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Book Description
From first person accounts of pharmaceutical studies gone bad to intricate medical histories, Guinea Pig Zero provides a fascinating look at the people who sell their bodies to science. While the book provides advice to present-day research subjects (by rating research clinics), the book also provides context by investigating the history and ethics behind this important, but little-known medical industry.
Author: Robert Helms
Publisher: Garrett County Press
ISBN: 1891053280
Category : Biography & Autobiography
Languages : en
Pages : 270
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Book Description
From first person accounts of pharmaceutical studies gone bad to intricate medical histories, Guinea Pig Zero provides a fascinating look at the people who sell their bodies to science. While the book provides advice to present-day research subjects (by rating research clinics), the book also provides context by investigating the history and ethics behind this important, but little-known medical industry.
Author: Roberto Abadie
Publisher: Duke University Press
ISBN: 0822393247
Category : Social Science
Languages : en
Pages : 199
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Book Description
The Professional Guinea Pig documents the emergence of the professional research subject in Phase I clinical trials testing the safety of drugs in development. Until the mid-1970s Phase I trials were conducted on prisoners. After that practice was outlawed, the pharmaceutical industry needed a replacement population and began to aggressively recruit healthy, paid subjects, some of whom came to depend on the income, earning their living by continuously taking part in these trials. Drawing on ethnographic research among self-identified “professional guinea pigs” in Philadelphia, Roberto Abadie examines their experiences and views on the conduct of the trials and the risks they assume by participating. Some of the research subjects he met had taken part in more than eighty Phase I trials. While the professional guinea pigs tended to believe that most clinical trials pose only a moderate health risk, Abadie contends that the hazards presented by continuous participation, such as exposure to potentially dangerous drug interactions, are discounted or ignored by research subjects in need of money. The risks to professional guinea pigs are also disregarded by the pharmaceutical industry, which has become dependent on the routine participation of experienced research subjects. Arguing that financial incentives compromise the ethical imperative for informed consent to be freely given by clinical-trials subjects, Abadie confirms the need to reform policies regulating the participation of paid subjects in Phase I clinical trials.
Author: Margery Cuyler
Publisher: Walker Childrens
ISBN: 9780802797957
Category : Juvenile Fiction
Languages : en
Pages : 0
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Book Description
In bouncy, appealing rhyme, young readers are introduced to a classroom with a hairy problem-guinea pigs that keep adding and adding! From one lonely guinea pig to two to five and all the way up to twenty, the kids find that having a classroom pet is more than they bargained for. Finally, each student gets to take a guinea pig home, until they are left with zero. That is, until Mr. Gilbert brings in a rabbit with a growing belly . . . ! From master storyteller Margery Cuyler and with energetic illustrations from Tracey Campbell Pearson, Guinea Pigs Add Up is perfect for budding mathematicians-or anyone with a love for unruly animals.
Author: Gary Marcus
Publisher: Penguin
ISBN: 110155228X
Category : Music
Languages : en
Pages : 252
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Book Description
On the eve of his 40th birthday, Gary Marcus, a renowned scientist with no discernible musical talent, learns to play the guitar and investigates how anyone—of any age —can become musical. Do you have to be born musical to become musical? Do you have to start at the age of six? Using the tools of his day job as a cognitive psychologist, Gary Marcus becomes his own guinea pig as he takes up the guitar. In a powerful and incisive look at how both children and adults become musical, Guitar Zero traces Marcus’s journey, what he learned, and how anyone else can learn, too. A groundbreaking peek into the origins of music in the human brain, this musical journey is also an empowering tale of the mind’s enduring plasticity. Marcus investigates the most effective ways to train body and brain to learn to play an instrument, in a quest that takes him from Suzuki classes to guitar gods. From deliberate and efficient practicing techniques to finding the right music teacher, Marcus translates his own experience—as well as reflections from world-renowned musicians—into practical advice for anyone hoping to become musical, or to learn a new skill. Guitar Zero debunks the popular theory of an innate musical instinct while simultaneously challenging the idea that talent is only a myth. While standing the science of music on its head, Marcus brings new insight into humankind’s most basic question: what counts as a life well lived? Does one have to become the next Jimi Hendrix to make a passionate pursuit worthwhile, or can the journey itself bring the brain lasting satisfaction? For all those who have ever set out to play an instrument—or wish that they could—Guitar Zero is an inspiring and fascinating look at the pursuit of music, the mechanics of the mind, and the surprising rewards that come from following one’s dreams.
Author: Rebecca Dresser
Publisher: Oxford University Press
ISBN: 0190459271
Category : Medical
Languages : en
Pages : 321
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Book Description
The research ethics system was created without the help of people who know what it is like to be a research subject. This is a serious omission. Experts have overlooked ethical issues that matter to subjects. Silent Partners moves subjects to the forefront, giving them a voice in research ethics.
Author: Sonia Shah
Publisher: New Press, The
ISBN: 1595588310
Category : Medical
Languages : en
Pages : 257
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Book Description
Hailed by John le Carré as “an act of courage on the part of its author” and singled out for praise by the leading medical journals in the United States and the United Kingdom, The Body Hunters uncovers the real-life story behind le Carré's acclaimed novel The Constant Gardener and the feature film based on it. "A trenchant exposé . . . meticulously researched and packed with documentary evidence" (Publishers Weekly), Sonia Shah's riveting journalistic account shines a much-needed spotlight on a disturbing new global trend. Drawing on years of original research and reporting in Africa and Asia, Shah examines how the multinational pharmaceutical industry, in its quest to develop lucrative drugs, has begun exporting its clinical research trials to the developing world, where ethical oversight is minimal and desperate patients abound. As the New England Journal of Medicine notes, “it is critical that those engaged in drug development, clinical research and its oversight, research ethics, and policy know about these stories,” which tell of an impossible choice being faced by many of the world's poorest patients—be experimented upon or die for lack of medicine.
Author: Eileen Welsome
Publisher: Delta
ISBN: 0307767337
Category : History
Languages : en
Pages : 724
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Book Description
When the vast wartime factories of the Manhattan Project began producing plutonium in quantities never before seen on earth, scientists working on the top-secret bomb-building program grew apprehensive. Fearful that plutonium might cause a cancer epidemic among workers and desperate to learn more about what it could do to the human body, the Manhattan Project's medical doctors embarked upon an experiment in which eighteen unsuspecting patients in hospital wards throughout the country were secretly injected with the cancer-causing substance. Most of these patients would go to their graves without ever knowing what had been done to them. Now, in The Plutonium Files, Pulitzer Prize-winning reporter Eileen Welsome reveals for the first time the breadth of the extraordinary fifty-year cover-up surrounding the plutonium injections, as well as the deceitful nature of thousands of other experiments conducted on American citizens in the postwar years. Welsome's remarkable investigation spans the 1930s to the 1990s and draws upon hundreds of newly declassified documents and other primary sources to disclose this shadowy chapter in American history. She gives a voice to such innocents as Helen Hutchison, a young woman who entered a prenatal clinic in Nashville for a routine checkup and was instead given a radioactive "cocktail" to drink; Gordon Shattuck, one of several boys at a state school for the developmentally disabled in Massachusetts who was fed radioactive oatmeal for breakfast; and Maude Jacobs, a Cincinnati woman suffering from cancer and subjected to an experimental radiation treatment designed to help military planners learn how to win a nuclear war. Welsome also tells the stories of the scientists themselves, many of whom learned the ways of secrecy on the Manhattan Project. Among them are Stafford Warren, a grand figure whose bravado masked a cunning intelligence; Joseph Hamilton, who felt he was immune to the dangers of radiation only to suffer later from a fatal leukemia; and physician Louis Hempelmann, one of the most enthusiastic supporters of the plan to inject humans with potentially carcinogenic doses of plutonium. Hidden discussions of fifty years past are reconstructed here, wherein trusted government officials debated the ethical and legal implications of the experiments, demolishing forever the argument that these studies took place in a less enlightened era. Powered by her groundbreaking reportage and singular narrative gifts, Eileen Welsome has created a work of profound humanity as well as major historical significance. From the Hardcover edition.
Author: Carl Elliott
Publisher: Beacon Press
ISBN: 0807061441
Category : Medical
Languages : en
Pages : 233
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Book Description
By New Yorker and Atlantic writer Carl Elliott, a readable and even funny account of the serious business of medicine. A tongue-in-cheek account of the changes that have transformed medicine into big business. Physician and medical ethicist Carl Elliott tracks the new world of commercialized medicine from start to finish, introducing the professional guinea pigs, ghostwriters, thought leaders, drug reps, public relations pros, and even medical ethicists who use medicine for (sometimes huge) financial gain. Along the way, he uncovers the cost to patients lost in a health-care universe centered around consumerism.
Author: Osagie K. Obasogie
Publisher: Univ of California Press
ISBN: 0520961943
Category : Social Science
Languages : en
Pages : 547
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Book Description
For decades, the field of bioethics has shaped the way we think about ethical problems in science, technology, and medicine. But its traditional emphasis on individual interests such as doctor-patient relationships, informed consent, and personal autonomy is minimally helpful in confronting the social and political challenges posed by new human biotechnologies such as assisted reproduction, human genetic modification, and DNA forensics. Beyond Bioethics addresses these provocative issues from an emerging standpoint that is attentive to race, gender, class, disability, privacy, and notions of democracy—a "new biopolitics." This authoritative volume provides an overview for those grappling with the profound dilemmas posed by these developments. It brings together the work of cutting-edge thinkers from diverse fields of study and public engagement, all of them committed to this new perspective grounded in social justice and public interest values.
Author:
Publisher:
ISBN:
Category : Environmental health
Languages : en
Pages : 1520
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Book Description
