Micro-, Meso- and Macro-Connectomics of the Brain PDF Download
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Author: Henry Kennedy
Publisher: Springer
ISBN: 3319277774
Category : Medical
Languages : en
Pages : 173
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Book Description
This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Author: Henry Kennedy
Publisher: Springer
ISBN: 3319277774
Category : Medical
Languages : en
Pages : 173
Get Book Here
Book Description
This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Author: Allen Timothy Newton
Publisher:
ISBN:
Category : Brain
Languages : en
Pages : 125
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Book Description
Author: Lorena Deuker
Publisher:
ISBN:
Category :
Languages : en
Pages : 64
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Book Description
Author: Viktor K. Jirsa
Publisher: Springer
ISBN: 3540715126
Category : Technology & Engineering
Languages : en
Pages : 525
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Book Description
Our contemporary understanding of brain function is deeply rooted in the ideas of the nonlinear dynamics of distributed networks. Cognition and motor coordination seem to arise from the interactions of local neuronal networks, which themselves are connected in large scales across the entire brain. The spatial architectures between various scales inevitably influence the dynamics of the brain and thereby its function. But how can we integrate brain connectivity amongst these structural and functional domains? Our Handbook provides an account of the current knowledge on the measurement, analysis and theory of the anatomical and functional connectivity of the brain. All contributors are leading experts in various fields concerning structural and functional brain connectivity. In the first part of the Handbook, the chapters focus on an introduction and discussion of the principles underlying connected neural systems. The second part introduces the currently available non-invasive technologies for measuring structural and functional connectivity in the brain. Part three provides an overview of the analysis techniques currently available and highlights new developments. Part four introduces the application and translation of the concepts of brain connectivity to behavior, cognition and the clinical domain.
Author: Alex Fornito
Publisher: Academic Press
ISBN: 0124081185
Category : Medical
Languages : en
Pages : 496
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Book Description
Fundamentals of Brain Network Analysis is a comprehensive and accessible introduction to methods for unraveling the extraordinary complexity of neuronal connectivity. From the perspective of graph theory and network science, this book introduces, motivates and explains techniques for modeling brain networks as graphs of nodes connected by edges, and covers a diverse array of measures for quantifying their topological and spatial organization. It builds intuition for key concepts and methods by illustrating how they can be practically applied in diverse areas of neuroscience, ranging from the analysis of synaptic networks in the nematode worm to the characterization of large-scale human brain networks constructed with magnetic resonance imaging. This text is ideally suited to neuroscientists wanting to develop expertise in the rapidly developing field of neural connectomics, and to physical and computational scientists wanting to understand how these quantitative methods can be used to understand brain organization. - Winner of the 2017 PROSE Award in Biomedicine & Neuroscience and the 2017 British Medical Association (BMA) Award in Neurology - Extensively illustrated throughout by graphical representations of key mathematical concepts and their practical applications to analyses of nervous systems - Comprehensively covers graph theoretical analyses of structural and functional brain networks, from microscopic to macroscopic scales, using examples based on a wide variety of experimental methods in neuroscience - Designed to inform and empower scientists at all levels of experience, and from any specialist background, wanting to use modern methods of network science to understand the organization of the brain
Author: National Academy of Sciences
Publisher: National Academies Press
ISBN: 0309045290
Category : Medical
Languages : en
Pages : 195
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Book Description
The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."
Author: Gregory Hickok
Publisher: Academic Press
ISBN: 0124078621
Category : Psychology
Languages : en
Pages : 1188
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Book Description
Neurobiology of Language explores the study of language, a field that has seen tremendous progress in the last two decades. Key to this progress is the accelerating trend toward integration of neurobiological approaches with the more established understanding of language within cognitive psychology, computer science, and linguistics. This volume serves as the definitive reference on the neurobiology of language, bringing these various advances together into a single volume of 100 concise entries. The organization includes sections on the field's major subfields, with each section covering both empirical data and theoretical perspectives. "Foundational" neurobiological coverage is also provided, including neuroanatomy, neurophysiology, genetics, linguistic, and psycholinguistic data, and models. - Foundational reference for the current state of the field of the neurobiology of language - Enables brain and language researchers and students to remain up-to-date in this fast-moving field that crosses many disciplinary and subdisciplinary boundaries - Provides an accessible entry point for other scientists interested in the area, but not actively working in it – e.g., speech therapists, neurologists, and cognitive psychologists - Chapters authored by world leaders in the field – the broadest, most expert coverage available
Author: Janine Bijsterbosch
Publisher: Oxford University Press
ISBN: 0192535757
Category : Medical
Languages : en
Pages : 287
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Book Description
Spontaneous 'resting-state' fluctuations in neuronal activity offer insights into the inherent organisation of the human brain, and may provide markers for diagnosis and treatment of mental disorders. Resting state functional magnetic resonance imaging (fMRI) can be used to investigate intrinsic functional connectivity networks, which are identified based on similarities in the signal measured from different regions. From data acquisition to results interpretation, An Introduction to Resting State fMRI Functional Connectivity discusses a wide range of approaches without expecting previous knowledge of the reader, making it truly accessible to readers from a broad range of backgrounds. Supplemented with online examples to enable the reader to obtain hands-on experience working with data, the text also provides details to enhance learning for those already experienced in the field. The Oxford Neuroimaging Primers are written for new researchers or advanced undergraduates in neuroimaging to provide a thorough understanding of the ways in which neuroimaging data can be analysed and interpreted. Aimed at students without a background in mathematics or physics, this book is also important reading for those familiar with task fMRI but new to the field of resting state fMRI.
Author: Karl J. Friston
Publisher: Elsevier
ISBN: 0080472958
Category : Medical
Languages : en
Pages : 1161
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Book Description
This updated second edition provides the state of the art perspective of the theory, practice and application of modern non-invasive imaging methods employed in exploring the structural and functional architecture of the normal and diseased human brain. Like the successful first edition, it is written by members of the Functional Imaging Laboratory - the Wellcome Trust funded London lab that has contributed much to the development of brain imaging methods and their application in the last decade. This book should excite and intrigue anyone interested in the new facts about the brain gained from neuroimaging and also those who wish to participate in this area of brain science.* Represents an almost entirely new book from 1st edition, covering the rapid advances in methods and in understanding of how human brains are organized* Reviews major advances in cognition, perception, emotion and action* Introduces novel experimental designs and analytical techniques made possible with fMRI, including event-related designs and non-linear analysis
Author: Hans O. Lüders
Publisher: CRC Press
ISBN: 1000148955
Category : Medical
Languages : en
Pages : 396
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Book Description
Deep brain stimulation has been used effectively for many years to treat patients suffering from Parkinson's disease. Now, neurologists and neurosurgeons are using electric pulse generators to block abnormal activity, i.e. epileptic fits. Promising research results indicate that electric pulses implanted deep in the brain can affect neurocircuitry and help stop oncoming seizures. Supplying a solid background on brain stimulation and its application to epilepsy, Deep Brain Stimulation and Epilepsy provides a historical overview, explores pathogenesis of brain stimulation, discusses animal experiments and human studies, and explores future prospects of brain stimulation for epileptic control. The editor and his team of contributors distill information drawn directly from the literature into one convenient resource.
