Frontiers in Anti-Infective Drug Discovery: Volume 9

Frontiers in Anti-Infective Drug Discovery: Volume 9 PDF Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
ISBN: 1681088304
Category : Medical
Languages : en
Pages : 229

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Book Description
This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the book series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field. The ninth volume of this series features 5 reviews that cover some aspects of clinical and pre-clinical antimicrobial drug development, with 2 chapters focusing on drugs to treat leishmaniasis and dengue fever, respectively. - Use of preclinical and early clinical data for accelerating antimicrobial drug development - Post-translational modifications: host defence mechanism, pathogenic weapon, and emerged target of anti-infective drugs - Scope and limitations on the potent antimicrobial activities of hydrazone derivatives - Current scenario of anti-leishmanial drugs and treatment - Dengue hemorrhagic fever: the potential repurposing drugs

Frontiers in Anti-Infective Drug Discovery: Volume 9

Frontiers in Anti-Infective Drug Discovery: Volume 9 PDF Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
ISBN: 1681088304
Category : Medical
Languages : en
Pages : 229

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Book Description
This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the book series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field. The ninth volume of this series features 5 reviews that cover some aspects of clinical and pre-clinical antimicrobial drug development, with 2 chapters focusing on drugs to treat leishmaniasis and dengue fever, respectively. - Use of preclinical and early clinical data for accelerating antimicrobial drug development - Post-translational modifications: host defence mechanism, pathogenic weapon, and emerged target of anti-infective drugs - Scope and limitations on the potent antimicrobial activities of hydrazone derivatives - Current scenario of anti-leishmanial drugs and treatment - Dengue hemorrhagic fever: the potential repurposing drugs

Frontiers in Clinical Drug Research-Anti Infectives: Volume 9

Frontiers in Clinical Drug Research-Anti Infectives: Volume 9 PDF Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
ISBN: 9815179829
Category : Science
Languages : en
Pages : 205

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Book Description
Frontiers in Clinical Drug Research – Anti Infectives (Volume 9) is a book series that provides updated reviews on the latest advancements in development of pharmaceutical agents for treating infectious diseases. The series covers various topics, including chemistry, pharmacology, molecular biology, and biochemistry of natural and synthetic drugs. Additionally, it addresses multi-drug resistance and pre-clinical/clinical findings on antibiotics, vaccines, antifungal agents, and antitubercular drugs. This series is an invaluable resource for pharmaceutical scientists and postgraduate students, offering critical information to support clinical trials and research in anti-infective drug discovery and epidemiology. The ninth volume presents five in-depth reviews, with topics including mature drugs and antivirals for COVID-19, bacteriocins as potent anti-infective agents, therapeutic interventions targeting free radicals in viral diseases, and a detailed exploration of natural anti-infective agents. The five reviews included in this volume are: - The role of mature drugs in the COVID-19 era - Antivirals to treat COVID-19 - Ribosomally synthesized bacteriocins as potent anti-infective agents - Therapeutic interventions against free radicals in viral diseases - A comprehensive overview of natural anti-infective agents.

Frontiers in Anti-Infective Drug Discovery: Volume 10

Frontiers in Anti-Infective Drug Discovery: Volume 10 PDF Author: M. Iqbal Choudhary
Publisher: Bentham Science Publishers
ISBN: 1681089351
Category : Medical
Languages : en
Pages : 168

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Book Description
Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field. The tenth volume of this series features 4 reviews on the following topics: -Pharmacotherapy of Posterior Segment Ocular Infections -Discovery and Development of Antimalarial Drug-Resistance Reversal Agents -Omics Technologies and Anti-Infective Drug Discovery -Possible Cutaneous Adverse Effects of Anti-Infective Vaccinations

Frontiers in Anti-Infective Drug Discovery: Volume 8

Frontiers in Anti-Infective Drug Discovery: Volume 8 PDF Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
ISBN: 9811412375
Category : Medical
Languages : en
Pages : 277

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Book Description
This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the book series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field. The eighth volume of this series features 8 chapters that cover methods for antimicrobial drug discovery (with 2 chapters that focus on genomics) as well as updates on drug development against Helicobacter pylori and emerging coronaviruses, among other interesting topics: - Eradication of Helicobacter pylori Infection with Non-Bismuth Quadruple Concomitant Therapy - Drug Discovery Strategies Against Emerging Coronaviruses: A Global Threat - Opportunities Offered By Fragment-Based Drug Design in Antibiotic Development - Phage therapy as a Tool for Control of Foodborne Diseases: Advantages and Limitations - Subtractive Genomics Approaches: Towards Anti-Bacterial Drug Discovery - Recent Advances in the Discovery of Antimicrobials through Metagenomics - Phyto-Nano-Antimicrobials: Synthesis, Characterization, Discovery, and Advances - Aptamers as Anti-infective Agents.

Frontiers in Anti-Infective Drug Discovery

Frontiers in Anti-Infective Drug Discovery PDF Author: Atta-ur- Rahman
Publisher: Bentham Science Publishers
ISBN: 1681085623
Category : Medical
Languages : en
Pages : 293

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Book Description
This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the book series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field. The seventh volume of this series features 7 chapters that cover the following topics: - Gut micriobiota and gastrointestinal cancer - Dengue virus infections - Synergistic antibiotic drug interactions - Molecular modeling of antibacterial drugs - Nucleic acid aptamers as anti-infective agents - Fungal multidrug resistance - The role of hydrogen sulfide in infections.

Frontiers in Anti-Infective Agents: Volume 6

Frontiers in Anti-Infective Agents: Volume 6 PDF Author: Parvesh Singh
Publisher: Bentham Science Publishers
ISBN: 9814998435
Category : Medical
Languages : en
Pages : 194

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Book Description
Anti-infective agents are a distinct class of pharmacologically important molecules that have served mankind in different capacities to combat life-threatening pathological conditions. They include antibacterial, antifungal, antiviral, antituberculosis, antimalarial, and urinary anti-infective agents. However, evolutionary changes, adaptations, and the development of new strains of pathogenic microorganisms have reduced the therapeutic efficacy of existing drugs, thus, limiting their clinical utility over the years. Frontiers in Anti-Infective Agents Volume 6 is a collection of notable research efforts, successful anti-infective drug development programs, and a comprehensive overview of successful and unsuccessful clinical trials conducted in this domain. This volume continues from the last one with interesting reviews on 1) “Reverse Vaccinology” for vaccination design using computational data to identify vaccine targets, 2) leptospirosis, 3) phage therapy for bacterial infections, 4) quorum sensing inhibitors from natural products, and 5) nitrogen and oxygen-based heterocyclic compounds that can act as anti-infective agents. The volume, therefore, covers a range of frontier topics on anti-infective research and development. This compilation is a timely reference for postgraduate scholars and researchers seeking updates in specific areas of anti-infective drug development. Allied healthcare professionals (clinical and public healthcare professionals) can also benefit from the information presented within.

Tuberculosis Treatment: The Search For New Drugs

Tuberculosis Treatment: The Search For New Drugs PDF Author: Marcus V.N. de Souza
Publisher: Bentham Science Publishers
ISBN: 1608057887
Category : Medical
Languages : en
Pages : 236

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Book Description
Despite the high impact on human health caused by Tuberculosis (TB) infections worldwide, nearly 45 years have passed since a novel drug was introduced for its treatment. As MDR-TB and XDR-TB cases rise globally new strategies and drugs are desperately needed to address this problem. Tuberculosis Treatment: The Search For New Drugs covers a wide range of topics about TB drug discovery. The e-book begins with historical information about Tuberculosis discovery and treatment and explores modern treatment strategies, formulations (synthetic and natural) and class of compounds. The extraction of important drugs from various sources is also covered in separate chapters along with information about promising drugs undergoing clinical testing. The e-book is a useful reference for readers interested in learning about the array of pharmaceuticals discovered and used to combat Mycobacterium tuberculosis infections.

21st Century Challenges in Antimicrobial Therapy and Stewardship

21st Century Challenges in Antimicrobial Therapy and Stewardship PDF Author: Islam M. Ghazi
Publisher: Bentham Science Publishers
ISBN: 9811461813
Category : Medical
Languages : en
Pages : 493

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Book Description
21st Century Challenges in Antimicrobial Therapy and Stewardship addresses selected topics that are of importance in the practice of infectious disease management. The text starts by illustrating the global landscape of antimicrobial drug resistance, which influences antimicrobial use and therapeutic decisions in the clinic. The contributors explain the reasons for the spread of antibiotic resistance, the pharmacology of antibiotics of different classes, innovative drug delivery methods which can improve the efficacy and safety of new drug candidates and achieve targeted drug delivery as well as drug resistance monitoring techniques and issues in the practice of antimicrobial stewardship and infection control. Key Features: - 14 organized chapters on several aspects of antimicrobial therapy and stewardship - Introductory knowledge on global antimicrobial trends - Coverage of molecular basis of antimicrobial resistance in gram positive, gram negative and fungal microbes - Focused coverage on new developments in antimicrobial drug development, drug delivery, formulation and diagnostic tools - Information on unmet needs of patients and clinicians, including the treatment of difficult infections - Comprehensive coverage of issues in antimicrobial stewardship 21st Century Challenges in Antimicrobial Therapy and Stewardship brings to readers – healthcare administrators, educators, pharmacists, clinicians and students, alike – the knowledge of the molecular basis of antimicrobial drug therapy, drug resistance in pathogens and current practices in antimicrobial stewardship programs. This knowledge, in turn, fosters an awareness among healthcare industry participants to collaborate in an interprofessional environment to combat multidrug resistance.

Frontiers in Clinical Drug Research - CNS and Neurological Disorders

Frontiers in Clinical Drug Research - CNS and Neurological Disorders PDF Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
ISBN: 1608057755
Category : Science
Languages : en
Pages : 373

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Book Description
Frontiers in Clinical Drug Research - CNS and Neurological Disorders is an ebook series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the ebook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology. The second volume of this series features 8 chapters that cover a variety of topics including: -treatment of multiple sclerosis and schizophrenia -neurochemistry of tremors -relationship between GABA and Alzheimer’s disease therapy -relationship between neurological diseases and cancer -research on angiogenesis-related blindness

Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 9

Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 9 PDF Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
ISBN: 168108905X
Category : Science
Languages : en
Pages : 279

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Book Description
Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology. The ninth volume of this series features reviews that cover the following topics related to the treatment of a different CNS disorders, related diseases and basic neuropharmacology research: - Integrating imaging and microdialysis into systems neuropharmacology - Depression heterogeneity and the potential of a transdiagnostic and dimensional approach to identify biologically relevant phenotypes - CAR-T cells in brain tumors and autoimmune diseases – from basics to the clinic - Revaluation of thyrotropin-releasing hormone and its mimetics as candidates for treating a wide range of neurological and psychiatric disorders - Natural BACE1 inhibitors: promising drugs for the management of Alzheimer’s disease - The possibilities of safe lithium therapy in the treatment of neurological and psychoemotional disorders - Pharmacotherapy of multiple sclerosis and treatment strategies