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Author: Arjen Hommersom
Publisher: Springer
ISBN: 3319280074
Category : Computers
Languages : en
Pages : 336
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Book Description
Medicine and health care are currently faced with a significant rise in their complexity. This is partly due to the progress made during the past three decades in the fundamental biological understanding of the causes of health and disease at the molecular, (sub)cellular, and organ level. Since the end of the 1970s, when knowledge representation and reasoning in the biomedical field became a separate area of research, huge progress has been made in the development of methods and tools that are finally able to impact on the way medicine is being practiced. Even though there are huge differences in the techniques and methods used by biomedical researchers, there is now an increasing tendency to share research results in terms of formal knowledge representation methods, such as ontologies, statistical models, network models, and mathematical models. As there is an urgent need for health-care professionals to make better decisions, computer-based support using this knowledge is now becoming increasingly important. It may also be the only way to integrate research results from the different parts of the spectrum of biomedical and clinical research. The aim of this book is to shed light on developments in knowledge representation at different levels of biomedical application, ranging from human biology to clinical guidelines, and using different techniques, from probability theory and differential equations to logic. The book starts with two introductory chapters followed by 18 contributions organized in the following topical sections: diagnosis of disease; monitoring of health and disease and conformance; assessment of health and personalization; prediction and prognosis of health and disease; treatment of disease; and recommendations.
Author: Arjen Hommersom
Publisher: Springer
ISBN: 3319280074
Category : Computers
Languages : en
Pages : 336
Get Book Here
Book Description
Medicine and health care are currently faced with a significant rise in their complexity. This is partly due to the progress made during the past three decades in the fundamental biological understanding of the causes of health and disease at the molecular, (sub)cellular, and organ level. Since the end of the 1970s, when knowledge representation and reasoning in the biomedical field became a separate area of research, huge progress has been made in the development of methods and tools that are finally able to impact on the way medicine is being practiced. Even though there are huge differences in the techniques and methods used by biomedical researchers, there is now an increasing tendency to share research results in terms of formal knowledge representation methods, such as ontologies, statistical models, network models, and mathematical models. As there is an urgent need for health-care professionals to make better decisions, computer-based support using this knowledge is now becoming increasingly important. It may also be the only way to integrate research results from the different parts of the spectrum of biomedical and clinical research. The aim of this book is to shed light on developments in knowledge representation at different levels of biomedical application, ranging from human biology to clinical guidelines, and using different techniques, from probability theory and differential equations to logic. The book starts with two introductory chapters followed by 18 contributions organized in the following topical sections: diagnosis of disease; monitoring of health and disease and conformance; assessment of health and personalization; prediction and prognosis of health and disease; treatment of disease; and recommendations.
Author: Ira J. Kalet
Publisher: Academic Press
ISBN: 0123914620
Category : Business & Economics
Languages : en
Pages : 709
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Book Description
This second edition of a pioneering technical work in biomedical informatics provides a very readable treatment of the deep computational ideas at the foundation of the field. Principles of Biomedical Informatics, 2nd Edition is radically reorganized to make it especially useable as a textbook for courses that move beyond the standard introductory material. It includes exercises at the end of each chapter, ideas for student projects, and a number of new topics, such as:• tree structured data, interval trees, and time-oriented medical data and their use• On Line Application Processing (OLAP), an old database idea that is only recently coming of age and finding surprising importance in biomedical informatics• a discussion of nursing knowledge and an example of encoding nursing advice in a rule-based system• X-ray physics and algorithms for cross-sectional medical image reconstruction, recognizing that this area was one of the most central to the origin of biomedical computing• an introduction to Markov processes, and• an outline of the elements of a hospital IT security program, focusing on fundamental ideas rather than specifics of system vulnerabilities or specific technologies. It is simultaneously a unified description of the core research concept areas of biomedical data and knowledge representation, biomedical information access, biomedical decision-making, and information and technology use in biomedical contexts, and a pre-eminent teaching reference for the growing number of healthcare and computing professionals embracing computation in health-related fields. As in the first edition, it includes many worked example programs in Common LISP, the most powerful and accessible modern language for advanced biomedical concept representation and manipulation. The text also includes humor, history, and anecdotal material to balance the mathematically and computationally intensive development in many of the topic areas. The emphasis, as in the first edition, is on ideas and methods that are likely to be of lasting value, not just the popular topics of the day. Ira Kalet is Professor Emeritus of Radiation Oncology, and of Biomedical Informatics and Medical Education, at the University of Washington. Until retiring in 2011 he was also an Adjunct Professor in Computer Science and Engineering, and Biological Structure. From 2005 to 2010 he served as IT Security Director for the University of Washington School of Medicine and its major teaching hospitals. He has been a member of the American Medical Informatics Association since 1990, and an elected Fellow of the American College of Medical Informatics since 2011. His research interests include simulation systems for design of radiation treatment for cancer, software development methodology, and artificial intelligence applications to medicine, particularly expert systems, ontologies and modeling. - Develops principles and methods for representing biomedical data, using information in context and in decision making, and accessing information to assist the medical community in using data to its full potential - Provides a series of principles for expressing biomedical data and ideas in a computable form to integrate biological, clinical, and public health applications - Includes a discussion of user interfaces, interactive graphics, and knowledge resources and reference material on programming languages to provide medical informatics programmers with the technical tools to develop systems
Author: Ira J. Kalet
Publisher: Academic Press
ISBN: 0080557945
Category : Computers
Languages : en
Pages : 503
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Book Description
Principles of Biomedial Informatics provides a foundation for understanding the fundamentals of biomedical informatics, which deals with the storage, retrieval, and use of biomedical data for biological problem solving and medical decision making. It covers the application of these principles to the three main biomedical domains of basic biology, clinical medicine, and public health. The author offers a coherent summary, focusing on the three core concept areas of biomedical data and knowledge representation: biomedical information access, biomedical decision making, and information and technology use in biomedical contexts. Develops principles and methods for representing biomedical data, using information in context and in decision making, and accessing information to assist the medical community in using data to its full potential Provides a series of principles for expressing biomedical data and ideas in a computable form to integrate biological, clinical, and public health applications Includes a discussion of user interfaces, interactive graphics, and knowledge resources and reference material on programming languages to provide medical informatics programmers with the technical tools to develop systems
Author: Dr. JANARDHAN KADARI
Publisher: Shashwat Publication
ISBN: 8119281101
Category : Science
Languages : en
Pages : 237
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Book Description
Mathematical and statistical concepts are applied to cellular and molecular biology, genetics, population genetics, quantitative blochemistry, nucleic acid chemistry, microbiology, biotechnology. medicine, pharmacy, numerical taxonomy, ecology and evolution.The Coalescing of genetics, mathematics, Computers has resulted in the emergence of bioinformatics. We talk of next generationn DNA sequencing and micro array. R was created by "Rossihaka and Robert Gentleman" at university of Auckland (New Zealand) currently developed by R development core team
Author: Indra Neil Sarkar
Publisher: Academic Press
ISBN: 0124016847
Category : Computers
Languages : en
Pages : 589
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Book Description
Beginning with a survey of fundamental concepts associated with data integration, knowledge representation, and hypothesis generation from heterogeneous data sets, Methods in Biomedical Informatics provides a practical survey of methodologies used in biological, clinical, and public health contexts. These concepts provide the foundation for more advanced topics like information retrieval, natural language processing, Bayesian modeling, and learning classifier systems. The survey of topics then concludes with an exposition of essential methods associated with engineering, personalized medicine, and linking of genomic and clinical data. Within an overall context of the scientific method, Methods in Biomedical Informatics provides a practical coverage of topics that is specifically designed for: (1) domain experts seeking an understanding of biomedical informatics approaches for addressing specific methodological needs; or (2) biomedical informaticians seeking an approachable overview of methodologies that can be used in scenarios germane to biomedical research. - Contributors represent leading biomedical informatics experts: individuals who have demonstrated effective use of biomedical informatics methodologies in the real-world, high-quality biomedical applications - Material is presented as a balance between foundational coverage of core topics in biomedical informatics with practical "in-the-trenches" scenarios. - Contains appendices that function as primers on: (1) Unix; (2) Ruby; (3) Databases; and (4) Web Services.
Author: Vishal Jain
Publisher: John Wiley & Sons
ISBN: 1119641381
Category : Computers
Languages : en
Pages : 384
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Book Description
With the advancements of semantic web, ontology has become the crucial mechanism for representing concepts in various domains. For research and dispersal of customized healthcare services, a major challenge is to efficiently retrieve and analyze individual patient data from a large volume of heterogeneous data over a long time span. This requirement demands effective ontology-based information retrieval approaches for clinical information systems so that the pertinent information can be mined from large amount of distributed data. This unique and groundbreaking book highlights the key advances in ontology-based information retrieval techniques being applied in the healthcare domain and covers the following areas: Semantic data integration in e-health care systems Keyword-based medical information retrieval Ontology-based query retrieval support for e-health implementation Ontologies as a database management system technology for medical information retrieval Information integration using contextual knowledge and ontology merging Collaborative ontology-based information indexing and retrieval in health informatics An ontology-based text mining framework for vulnerability assessment in health and social care An ontology-based multi-agent system for matchmaking patient healthcare monitoring A multi-agent system for querying heterogeneous data sources with ontologies for reducing cost of customized healthcare systems A methodology for ontology based multi agent systems development Ontology based systems for clinical systems: validity, ethics and regulation
Author: Stephen Muggleton
Publisher: Oxford University Press
ISBN: 0198862539
Category : Computers
Languages : en
Pages : 533
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Book Description
This book, authored by an array of internationally recognised researchers, is of direct relevance to all those involved in Academia and Industry wanting to obtain insights into the topics at the forefront of the revolution in Artificial Intelligence and Cognitive Science.
Author: Frank van Harmelen
Publisher: Elsevier
ISBN: 0080557023
Category : Computers
Languages : en
Pages : 1035
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Book Description
Handbook of Knowledge Representation describes the essential foundations of Knowledge Representation, which lies at the core of Artificial Intelligence (AI). The book provides an up-to-date review of twenty-five key topics in knowledge representation, written by the leaders of each field. It includes a tutorial background and cutting-edge developments, as well as applications of Knowledge Representation in a variety of AI systems. This handbook is organized into three parts. Part I deals with general methods in Knowledge Representation and reasoning and covers such topics as classical logic in Knowledge Representation; satisfiability solvers; description logics; constraint programming; conceptual graphs; nonmonotonic reasoning; model-based problem solving; and Bayesian networks. Part II focuses on classes of knowledge and specialized representations, with chapters on temporal representation and reasoning; spatial and physical reasoning; reasoning about knowledge and belief; temporal action logics; and nonmonotonic causal logic. Part III discusses Knowledge Representation in applications such as question answering; the semantic web; automated planning; cognitive robotics; multi-agent systems; and knowledge engineering. This book is an essential resource for graduate students, researchers, and practitioners in knowledge representation and AI. * Make your computer smarter* Handle qualitative and uncertain information* Improve computational tractability to solve your problems easily
Author: Pedro Barahona
Publisher: Springer Science & Business Media
ISBN: 354038409X
Category : Computers
Languages : en
Pages : 279
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Book Description
This book presents thoroughly arranged tutorial papers corresponding to lectures given by leading researchers at the Second International Summer School on Reasoning Web in Lisbon, Portugal, in September 2006. Building on the predessor school held in 2005 and published as LNCS 3564, the ten tutorial lectures presented provide competent coverage of current topics in semantic Web research and development.
Author: Manfred Stede
Publisher: Springer Nature
ISBN: 303102169X
Category : Computers
Languages : en
Pages : 175
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Book Description
Argumentation mining is an application of natural language processing (NLP) that emerged a few years ago and has recently enjoyed considerable popularity, as demonstrated by a series of international workshops and by a rising number of publications at the major conferences and journals of the field. Its goals are to identify argumentation in text or dialogue; to construct representations of the constellation of claims, supporting and attacking moves (in different levels of detail); and to characterize the patterns of reasoning that appear to license the argumentation. Furthermore, recent work also addresses the difficult tasks of evaluating the persuasiveness and quality of arguments. Some of the linguistic genres that are being studied include legal text, student essays, political discourse and debate, newspaper editorials, scientific writing, and others. The book starts with a discussion of the linguistic perspective, characteristics of argumentative language, and their relationship to certain other notions such as subjectivity. Besides the connection to linguistics, argumentation has for a long time been a topic in Artificial Intelligence, where the focus is on devising adequate representations and reasoning formalisms that capture the properties of argumentative exchange. It is generally very difficult to connect the two realms of reasoning and text analysis, but we are convinced that it should be attempted in the long term, and therefore we also touch upon some fundamentals of reasoning approaches. Then the book turns to its focus, the computational side of mining argumentation in text. We first introduce a number of annotated corpora that have been used in the research. From the NLP perspective, argumentation mining shares subtasks with research fields such as subjectivity and sentiment analysis, semantic relation extraction, and discourse parsing. Therefore, many technical approaches are being borrowed from those (and other) fields. We break argumentation mining into a series of subtasks, starting with the preparatory steps of classifying text as argumentative (or not) and segmenting it into elementary units. Then, central steps are the automatic identification of claims, and finding statements that support or oppose the claim. For certain applications, it is also of interest to compute a full structure of an argumentative constellation of statements. Next, we discuss a few steps that try to 'dig deeper': to infer the underlying reasoning pattern for a textual argument, to reconstruct unstated premises (so-called 'enthymemes'), and to evaluate the quality of the argumentation. We also take a brief look at 'the other side' of mining, i.e., the generation or synthesis of argumentative text. The book finishes with a summary of the argumentation mining tasks, a sketch of potential applications, and a--necessarily subjective--outlook for the field.
