Finite-Size Effects in Stochastic Models of Population Dynamics: Applications to Biomedicine and Biology PDF Download
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Author: Francesca Di Patti
Publisher: Firenze University Press
ISBN: 8884539765
Category : Science
Languages : en
Pages : 128
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Book Description
Author: Francesca Di Patti
Publisher: Firenze University Press
ISBN: 8884539765
Category : Science
Languages : en
Pages : 128
Get Book Here
Book Description
Author: Francesca Di Patti
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Author: Sylvie Meleard
Publisher: Springer
ISBN: 3319217119
Category : Mathematics
Languages : en
Pages : 111
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Book Description
In this contribution, several probabilistic tools to study population dynamics are developed. The focus is on scaling limits of qualitatively different stochastic individual based models and the long time behavior of some classes of limiting processes. Structured population dynamics are modeled by measure-valued processes describing the individual behaviors and taking into account the demographic and mutational parameters, and possible interactions between individuals. Many quantitative parameters appear in these models and several relevant normalizations are considered, leading to infinite-dimensional deterministic or stochastic large-population approximations. Biologically relevant questions are considered, such as extinction criteria, the effect of large birth events, the impact of environmental catastrophes, the mutation-selection trade-off, recovery criteria in parasite infections, genealogical properties of a sample of individuals. These notes originated from a lecture series on Structured Population Dynamics at Ecole polytechnique (France). Vincent Bansaye and Sylvie Méléard are Professors at Ecole Polytechnique (France). They are a specialists of branching processes and random particle systems in biology. Most of their research concerns the applications of probability to biodiversity, ecology and evolution.
Author: Enzo Marino
Publisher: Firenze University Press
ISBN: 8866550515
Category : Coastal engineering
Languages : en
Pages : 232
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Book Description
This thesis presents a numerical model capable of simulating offshore wind turbines exposed to extreme loading conditions. External condition-based extreme responses are reproduced by coupling a fully nonlinear wave kinematic solver with a hydro-aero-elastic simulator. First, a two-dimensional fully nonlinear wave simulator is developed. The transient nonlinear free surface problem is formulated assuming the potential theory and a high-order boundary element method is implemented to discretize Laplace's equation. For temporal evolution a second-order Taylor series expansion is used. The code, after validation with experimental data, is successfully adopted to simulate overturning plunging breakers which give rise to dangerous impact loads when they break against wind turbine substructures. Emphasis is then placed on the random nature of the waves. Indeed, through a domain decomposition technique a global simulation framework embedding the numerical wave simulator into a more general stochastic environment is developed. The proposed model is meant as a contribution to meet the more and more pressing demand for research in the offshore wind energy sector as it permits taking into account dangerous effects on the structural response so as to increase the global structural safety level.
Author: Marco Inzitari
Publisher: Firenze University Press
ISBN: 8884539161
Category : Medical
Languages : en
Pages : 62
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Book Description
Gait and mobility are cardinal to maintain autonomy and independency in daily life, also for older persons. Changes in these functions might be critical in the transition towards disability and loss of autonomy during the aging process. The aim of the present work, which collects three years of research conducted between Italy and the United States, was to assess some of the main risk factors for the progressive impairment of mobility and gait in older adults living in the community. According to our results, abnormalities in the nervous and cardiovascular systems, even subtle, are associated with a subsequent worsening of these functions. These data might help to better understand the progressive development of disability in the elderly, and in the future might also have practical implications for prevention.
Author: Maria Di Rosa
Publisher: Firenze University Press
ISBN: 8855184199
Category : Science
Languages : en
Pages : 224
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Book Description
In this work the central area of Corsica island was studied in order to reconstruct the tectono-metamorphic history of the continental and oceanic high pressure units that occupy the structurally deeper levels of the tectonic stacking of Alpine Corsica and their stratigraphic and structural relationship with the European margin (Hercynian Corsica). The study includes the geological mapping, the mesoscale and microscale structural analysis, the acquisition of chemical analyzes and micromaps with the microprobe, thermobarometric estimation through specific methodologies for metapelites, U-Th-Pb dating of zircons and allanites. The results obtained allows to reconstruct the geodynamic model of this sector of the Alpine belt from the Permian to the Burdigalian.
Author: Laura Colzi
Publisher: Firenze University Press
ISBN: 8855183796
Category : Science
Languages : en
Pages : 232
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Book Description
One of the most important tools to investigate the chemical history of our Galaxy and our own Solar System is to measure the isotopic fractionation of chemical elements. In the present study new astronomical observations devoted to the study of hydrogen and nitrogen fractionation (D/H and 14N/15N ratios) of molecules, towards massive star-forming regions in different evolutionary phases, have been presented. Moreover, a new detailed theoretical study of carbon fractionation, 12C/13C ratios, has been done. One of the main results was the confirmation that the 14N/15N ratio increases with the galactocentric distance, as predicted by stellar nucleosynthesis Galactic chemical evolution models. This work gives new important inputs on the understanding of local chemical processes that favor the production of molecules with different isotopes in star-forming regions.
Author: Raffaella Valenti
Publisher: Firenze University Press
ISBN: 8864537783
Category :
Languages : en
Pages : 184
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Author: Dalila De Vita
Publisher: Firenze University Press
ISBN: 8855183435
Category : Medical
Languages : en
Pages : 68
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Book Description
Malformations of cortical development (MCDs) result from a disruption in the process of the human brain cortex formation: currently, there are no pharmacological treatments for diffuse MCDs. Next-generation sequencing has accelerated the identification of MCDs causing genes: in some cases, functional studies are needed to clarify the role of genetic variants. The aim of this PhD project has been to apply a multidisciplinary approach to identify causative mutations in patients with MCDs, validate the pathogenic role of the identified mutations, and assess the effectiveness of novel in vitro treatment for mTOR pathway related MCDs.
Author: Marco Fondi
Publisher: Firenze University Press
ISBN: 8866550434
Category : Medical
Languages : en
Pages : 82
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Book Description
Bioinformatics, that is the interdisciplinary field that blends computer science and biostatistics with biological and biomedical sciences, is expected to gain a central role in next feature. Indeed, it has now affected several fields of biology, providing crucial hints for the understanding of biological systems and also allowing a more accurate design of wet lab experiments. In this work, the analysis of sequence data has be used in different fields, such as evolution (e.g. the assembly and evolution of metabolism), infections control (e.g. the horizontal flow of antibiotic resistance), ecology (bacterial bioremediation).
