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Author: Rebecca Sanft
Publisher: Academic Press
ISBN: 0128195967
Category : Science
Languages : en
Pages : 262
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Book Description
Exploring Mathematical Modeling in Biology through Case Studies and Experimental Activities provides supporting materials for courses taken by students majoring in mathematics, computer science or in the life sciences. The book's cases and lab exercises focus on hypothesis testing and model development in the context of real data. The supporting mathematical, coding and biological background permit readers to explore a problem, understand assumptions, and the meaning of their results. The experiential components provide hands-on learning both in the lab and on the computer. As a beginning text in modeling, readers will learn to value the approach and apply competencies in other settings. Included case studies focus on building a model to solve a particular biological problem from concept and translation into a mathematical form, to validating the parameters, testing the quality of the model and finally interpreting the outcome in biological terms. The book also shows how particular mathematical approaches are adapted to a variety of problems at multiple biological scales. Finally, the labs bring the biological problems and the practical issues of collecting data to actually test the model and/or adapting the mathematics to the data that can be collected. - Presents a single volume on mathematics and biological examples, with data and wet lab experiences suitable for non-experts - Contains three real-world biological case studies and one wet lab for application of the mathematical models - Includes R code templates throughout the text, which are also available through an online repository, along with the necessary data files to complete all projects and labs
Author: Rebecca Sanft
Publisher: Academic Press
ISBN: 0128195967
Category : Science
Languages : en
Pages : 262
Get Book Here
Book Description
Exploring Mathematical Modeling in Biology through Case Studies and Experimental Activities provides supporting materials for courses taken by students majoring in mathematics, computer science or in the life sciences. The book's cases and lab exercises focus on hypothesis testing and model development in the context of real data. The supporting mathematical, coding and biological background permit readers to explore a problem, understand assumptions, and the meaning of their results. The experiential components provide hands-on learning both in the lab and on the computer. As a beginning text in modeling, readers will learn to value the approach and apply competencies in other settings. Included case studies focus on building a model to solve a particular biological problem from concept and translation into a mathematical form, to validating the parameters, testing the quality of the model and finally interpreting the outcome in biological terms. The book also shows how particular mathematical approaches are adapted to a variety of problems at multiple biological scales. Finally, the labs bring the biological problems and the practical issues of collecting data to actually test the model and/or adapting the mathematics to the data that can be collected. - Presents a single volume on mathematics and biological examples, with data and wet lab experiences suitable for non-experts - Contains three real-world biological case studies and one wet lab for application of the mathematical models - Includes R code templates throughout the text, which are also available through an online repository, along with the necessary data files to complete all projects and labs
Author: Rebecca Sanft
Publisher: Academic Press
ISBN: 0128195959
Category : Science
Languages : en
Pages : 260
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Book Description
Exploring Mathematical Modeling in Biology through Case Studies and Experimental Activities provides supporting materials for courses taken by students majoring in mathematics, computer science or in the life sciences. The book's cases and lab exercises focus on hypothesis testing and model development in the context of real data. The supporting mathematical, coding and biological background permit readers to explore a problem, understand assumptions, and the meaning of their results. The experiential components provide hands-on learning both in the lab and on the computer. As a beginning text in modeling, readers will learn to value the approach and apply competencies in other settings. Included case studies focus on building a model to solve a particular biological problem from concept and translation into a mathematical form, to validating the parameters, testing the quality of the model and finally interpreting the outcome in biological terms. The book also shows how particular mathematical approaches are adapted to a variety of problems at multiple biological scales. Finally, the labs bring the biological problems and the practical issues of collecting data to actually test the model and/or adapting the mathematics to the data that can be collected.
Author: Olfa Boubaker
Publisher: Academic Press
ISBN: 0128226218
Category : Technology & Engineering
Languages : en
Pages : 398
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Book Description
Control Theory in Biomedical Engineering: Applications in Physiology and Medical Robotics highlights the importance of control theory and feedback control in our lives and explains how this theory is central to future medical developments. Control theory is fundamental for understanding feedback paths in physiological systems (endocrine system, immune system, neurological system) and a concept for building artificial organs. The book is suitable for graduate students and researchers in the control engineering and biomedical engineering fields, and medical students and practitioners seeking to enhance their understanding of physiological processes, medical robotics (legs, hands, knees), and controlling artificial devices (pacemakers, insulin injection devices).Control theory profoundly impacts the everyday lives of a large part of the human population including the disabled and the elderly who use assistive and rehabilitation robots for improving the quality of their lives and increasing their independence. - Gives an overview of state-of-the-art control theory in physiology, emphasizing the importance of this theory in the medical field through concrete examples, e.g., endocrine, immune, and neurological systems - Takes a comprehensive look at advances in medical robotics and rehabilitation devices and presents case studies focusing on their feedback control - Presents the significance of control theory in the pervasiveness of medical robots in surgery, exploration, diagnosis, therapy, and rehabilitation
Author: Brian P. Ingalls
Publisher: MIT Press
ISBN: 0262545829
Category : Science
Languages : en
Pages : 423
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Book Description
An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.
Author: David J. T. Sumpter
Publisher: Princeton University Press
ISBN: 1400837103
Category : Science
Languages : en
Pages : 313
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Book Description
How and why animals produce group behaviors Fish travel in schools, birds migrate in flocks, honeybees swarm, and ants build trails. How and why do these collective behaviors occur? Exploring how coordinated group patterns emerge from individual interactions, Collective Animal Behavior reveals why animals produce group behaviors and examines their evolution across a range of species. Providing a synthesis of mathematical modeling, theoretical biology, and experimental work, David Sumpter investigates how animals move and arrive together, how they transfer information, how they make decisions and synchronize their activities, and how they build collective structures. Sumpter constructs a unified appreciation of how different group-living species coordinate their behaviors and why natural selection has produced these groups. For the first time, the book combines traditional approaches to behavioral ecology with ideas about self-organization and complex systems from physics and mathematics. Sumpter offers a guide for working with key models in this area along with case studies of their application, and he shows how ideas about animal behavior can be applied to understanding human social behavior. Containing a wealth of accessible examples as well as qualitative and quantitative features, Collective Animal Behavior will interest behavioral ecologists and all scientists studying complex systems.
Author: Rita Borromeo Ferri
Publisher: Springer
ISBN: 3319680722
Category : Education
Languages : en
Pages : 163
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Book Description
This timely resource fills a gap in existing literature on mathematical modeling by presenting both theory- and evidence-based ideas for its teaching and learning. The book outlines four key professional competencies that must be developed in order to effectively and appropriately teach mathematical modeling, and in so doing it seeks to reduce the discrepancies between educational policy and educational research versus everyday teaching practice. Among the key competencies covered are: Theoretical competency for practical work. Task competency for instructional flexibility. Instructional competency for effective and quality lessons. Diagnostic competency for assessment and grading. Learning How to Teach Mathematical Modeling in School and Teacher Education is relevant to practicing and future mathematics teachers at all levels, as well as teacher educators, mathematics education researchers, and undergraduate and graduate mathematics students interested in research based methods for teaching mathematical modeling.
Author: Gloria Ann Stillman
Publisher: Springer
ISBN: 3319629689
Category : Education
Languages : en
Pages : 620
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Book Description
This volume documents on-going research and theorising in the sub-field of mathematics education devoted to the teaching and learning of mathematical modelling and applications. Mathematical modelling provides a way of conceiving and resolving problems in the life world of people whether these range from the everyday individual numeracy level to sophisticated new problems for society at large. Mathematical modelling and real world applications are considered as having potential for multi-disciplinary work that involves knowledge from a variety of communities of practice such as those in different workplaces (e.g., those of educators, designers, construction engineers, museum curators) and in different fields of academic endeavour (e.g., history, archaeology, mathematics, economics). From an educational perspective, researching the development of competency in real world modelling involves research situated in crossing the boundaries between being a student engaged in modelling or mathematical application to real word tasks in the classroom, being a teacher of mathematical modelling (in or outside the classroom or bridging both), and being a modeller of the world outside the classroom. This is the focus of many of the authors of the chapters in this book. All authors of this volume are members of the International Community of Teachers of Mathematical Modelling (ICTMA), the peak research body into researching the teaching and learning of mathematical modelling at all levels of education from the early years to tertiary education as well as in the workplace.
Author: Gabriele Kaiser
Publisher: Springer Science & Business Media
ISBN: 9400709102
Category : Education
Languages : en
Pages : 711
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Book Description
This book contains suggestions for and reflections on the teaching, learning and assessing of mathematical modelling and applications in a rapidly changing world, including teaching and learning environments. It addresses all levels of education from universities and technical colleges to secondary and primary schools. Sponsored by the International Community of Teachers of Mathematical Modelling and Applications (ICTMA), it reflects recent ideas and methods contributed by specialists from 30 countries in Africa, the Americas, Asia, Australia and Europe. Inspired by contributions to the Fourteenth Conference on the Teaching of Mathematical Modelling and Applications (ICTMA14) in Hamburg, 2009, the book describes the latest trends in the teaching and learning of mathematical modelling at school and university including teacher education. The broad and versatile range of topics will stress the international state-of-the-art on the following issues: Theoretical reflections on the teaching and learning of modelling Modelling competencies Cognitive perspectives on modelling Modelling examples for all educational levels Practice of modelling in school and at university level Practices in Engineering and Applications
Author: Edward A. Bender
Publisher: Courier Corporation
ISBN: 0486137120
Category : Mathematics
Languages : en
Pages : 273
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Book Description
Employing a practical, "learn by doing" approach, this first-rate text fosters the development of the skills beyond the pure mathematics needed to set up and manipulate mathematical models. The author draws on a diversity of fields — including science, engineering, and operations research — to provide over 100 reality-based examples. Students learn from the examples by applying mathematical methods to formulate, analyze, and criticize models. Extensive documentation, consisting of over 150 references, supplements the models, encouraging further research on models of particular interest. The lively and accessible text requires only minimal scientific background. Designed for senior college or beginning graduate-level students, it assumes only elementary calculus and basic probability theory for the first part, and ordinary differential equations and continuous probability for the second section. All problems require students to study and create models, encouraging their active participation rather than a mechanical approach. Beyond the classroom, this volume will prove interesting and rewarding to anyone concerned with the development of mathematical models or the application of modeling to problem solving in a wide array of applications.
Author: Eberhard Voit
Publisher: Garland Science
ISBN: 1351332937
Category : Computers
Languages : en
Pages : 783
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Book Description
A First Course in Systems Biology is an introduction for advanced undergraduate and graduate students to the growing field of systems biology. Its main focus is the development of computational models and their applications to diverse biological systems. The book begins with the fundamentals of modeling, then reviews features of the molecular inventories that bring biological systems to life and discusses case studies that represent some of the frontiers in systems biology and synthetic biology. In this way, it provides the reader with a comprehensive background and access to methods for executing standard systems biology tasks, understanding the modern literature, and launching into specialized courses or projects that address biological questions using theoretical and computational means. New topics in this edition include: default modules for model design, limit cycles and chaos, parameter estimation in Excel, model representations of gene regulation through transcription factors, derivation of the Michaelis-Menten rate law from the original conceptual model, different types of inhibition, hysteresis, a model of differentiation, system adaptation to persistent signals, nonlinear nullclines, PBPK models, and elementary modes. The format is a combination of instructional text and references to primary literature, complemented by sets of small-scale exercises that enable hands-on experience, and large-scale, often open-ended questions for further reflection.
