The Genetics of Drosophila PDF Download
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Author: Thomas Hunt Morgan
Publisher:
ISBN:
Category : Drosophila
Languages : en
Pages : 276
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Book Description
Author: Monroe W. Strickberger
Publisher: John Wiley & Sons
ISBN:
Category : Nature
Languages : en
Pages : 170
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Book Description
Drosophila life cycle; Preparation and maintenance of cultures techniques in handling flies and conducting experiments; Examination of wild-type and mutant flies; Statistical testing for experiments; Cell division and chromossomes; Monohybrid crosses; Dihybrid crosses; Linkage of three sex-linked genes; Analysis of different unknown genotypes; Genotype competition in a population cage; Localizing an unknown mutant; Multiple effects of single mutants; Fluorescent eye pigment chromatography; Measurement of developmental interaction between mutants; Phenocopies; Detection of X - chromosome lethals produced by irradiation; Localion and action of sex-linked lethals; Effect of random drift and different intensities of selection on mutant gene frequency.
Author: Thomas Hunt Morgan
Publisher:
ISBN:
Category : Drosophila
Languages : en
Pages : 276
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Book Description
Author: Ulrich Graf
Publisher: Springer Science & Business Media
ISBN: 3642768059
Category : Science
Languages : en
Pages : 233
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Book Description
The Biological Sciences are in the midst of a scientific rev olution. During the past decade under the rubric of molecu lar biology, chemistry and physics have assumed an integral role in biological research. This is especially true in ge netics, where the cloning of genes and the manipulation of genomic DNA have become in many organisms routine laboratory procedures. These noteworthy advances, it must be empha sized, especially in molecular genetics, are not autonomous. Rather, they have been accomplished with those organisms whose formal genetics has been documented in great detail. For the beginning student or the established investigator who is interested in pursuing eukaryote molecular genetic re search, Drosophila melanogaster, with its rich body of formal genetic information is one organism of choice. The book "Drosophila Genetics. A Practical Course" is an indispens able source of information for the beginner in the biology and formal genetics of Drosophila melanogaster. The scope of this guide, a revision and enlargement of the original German language version, is broad and instructive. The information included ranges from the simple, but necessary, details on how to culture and manipulate Drosophila flies to a series of more sophisticated genetic experiments. After completing the experiments detailed in the text, all students - neophyte or experienced - will be richly rewarded by having acquired a broad base of classical genetics information relevant for the biologist in its own right and prerequisite to Drosophila genetics research - formal and/or molecular. Davis, California, Melvin M.
Author: Seppo Lakovaara
Publisher: Springer Science & Business Media
ISBN: 1461583217
Category : Medical
Languages : en
Pages : 466
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Book Description
In 1906 Castle, Carpenter, Clarke, Mast, and Barrows published a paper entitled "The effects of inbreeding, cross-breeding, and selection upon the fertility and variability of Drosophila." This article, 55 pages long and published in the Proceedings of the Amer ican Academy, described experiments performed with Drosophila ampe lophila Lov, "a small dipterous insect known under various popular names such as the little fruit fly, pomace fly, vinegar fly, wine fly, and pickled fruit fly." This study, which was begun in 1901 and published in 1906, was the first published experimental study using Drosophila, subsequently known as Drosophila melanogaster Meigen. Of course, Drosophila was known before the experiments of Cas tles's group. The small flies swarming around grapes and wine pots have surely been known as long as wine has been produced. The honor of what was the first known misclassification of the fruit flies goes to Fabricius who named them Musca funebris in 1787. It was the Swedish dipterist, C.F. Fallen, who in 1823 changed the name of ~ funebris to Drosophila funebris which was heralding the beginning of the genus Drosophila. Present-day Drosophila research was started just 80 years ago and first published only 75 years ago. Even though the history of Drosophila research is short, the impact and volume of study on Drosophila has been tremendous during the last decades.
Author: Stephanie Elizabeth Mohr
Publisher: Harvard University Press
ISBN: 0674984730
Category : Science
Languages : en
Pages : 273
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Book Description
A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila’s importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases. Written by a leader in the Drosophila research community, First in Fly celebrates key insights uncovered by investigators using this model organism. Stephanie Elizabeth Mohr draws on these “first in fly” findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease.
Author: George A. Hudock
Publisher:
ISBN:
Category : Genetics
Languages : en
Pages : 114
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Book Description
Author: Manuel Marí-Beffa
Publisher: Cambridge University Press
ISBN: 9780521833158
Category : Science
Languages : en
Pages : 412
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Book Description
Originally published in 2005, this unique resource presents 27 easy-to-follow laboratory exercises for use in student practical classes in developmental biology. These experiments provide key insights into developmental questions, and many of them are described by the leaders in the field who carried out the original research. This book intends to bridge the gap between experimental work and the laboratory classes taken at the undergraduate and post-graduate levels. All chapters follow the same format, taking the students from materials and methods, through results and discussion, so that they learn the underlying rationale and analysis employed in the research. The book will be an invaluable resource for graduate students and instructors teaching practical developmental biology courses. Chapters include teaching concepts, discussion of the degree of difficulty of each experiment, potential sources of failure, as well as the time required for each experiment to be carried out in a class with students.
Author: Launcelot A. Owen
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Robert E. Kohler
Publisher: University of Chicago Press
ISBN: 0226450635
Category : Science
Languages : en
Pages : 337
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Book Description
"One of the most productive of all laboratory animals, Drosophila has been a key tool in genetics research for nearly a century. At the center of Drosophila culture from 1910 to 1940 was the school of Thomas Hunt Morgan and his students Alfred Sturtevant and Calvin Bridges, who, by inbreeding fruit flies, created a model laboratory creature - the 'standard' fly. By examining the material culture and working customs of Morgan's research group, [the author] brings to light essential features of the practice of experimental science. [This book] takes a broad view of experimental work, ranging from how the fly was introducted into the laboratory and how it was physically redesigned for use in genetic mapping, to how the 'Drosophilists' organized an international network for exchanging fly stocks that spread their practices around the world"--Back cover.
Author: Daryl S. Henderson
Publisher: Springer Science & Business Media
ISBN: 1592596657
Category : Science
Languages : en
Pages : 467
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Book Description
Leading drosophilists describe in step-by-step detail all the essential techniques for studying Drosophila chromosomes and suggest new avenues for scientific exploration. The chapters emphasize specimen preparation (from dissection to mounting) and cover both polytene and mitotic/meiotic chromosomes in depth. Each fully tested and readily reproducible protocol offers a background introduction, equipment and reagent lists, and tips on troubleshooting and avoiding pitfalls. A cutting-edge FISH and immunolocalization technique will be important for discovering how DNA sequence influences higher-order chromosome architecture and ultimately gene expression.
