Evolution of the Human Genome I

Evolution of the Human Genome I PDF Author: Naruya Saitou
Publisher: Springer
ISBN: 4431566031
Category : Science
Languages : en
Pages : 306

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Book Description
This book reviews the human genome from an evolutionary perspective. No such book has ever been published before, although there are many books on human genomes. There are two parts in this book: Overview of the Human Genome (Part I) and The Human Genome Viewed through Genes (Part II). In Part I, after a brief review of human evolution and the human genome (by Naruya Saitou), chapters on rubbish or junk DNA (by Dan Graur), GC content heterogeneity (by Satoshi Oota), protein coding and RNA coding genes (by Tadashi Imanishi), duplicated genes (by Takashi Kitano), recombinations (by Montanucci and Bertranpetit), and copy number variations including microsatellites (by Naoko Takezaki) are discussed. Readers can obtain various new insights on the human genome from this part. In Part II, genes in X and Y chromosomes (by Yoko Satta and others), HLA genes (by Timothy A. Jinam), opsin genes (by Shoji Kawamura and Amanda D. Melin), genes related to phenotypic variations (by Ryosuke Kimura), transcription factors (by Mahoko Takahashi and So Nakagawa), diabetes-related genes (by Ituro Inoue), disease genes in general (by Ituro Inoue and Hirofumi Nakaoka), and microbial genomes (by Chaochun Wei) are discussed. The human genome sequences were determined in 2004, and after more than 10 years we are now beginning to understand the human genome from an evolutionary point of view. This book furnishes readers with a good summary of current research in the field.

Evolution of the Human Genome I

Evolution of the Human Genome I PDF Author: Naruya Saitou
Publisher: Springer
ISBN: 4431566031
Category : Science
Languages : en
Pages : 306

Get Book Here

Book Description
This book reviews the human genome from an evolutionary perspective. No such book has ever been published before, although there are many books on human genomes. There are two parts in this book: Overview of the Human Genome (Part I) and The Human Genome Viewed through Genes (Part II). In Part I, after a brief review of human evolution and the human genome (by Naruya Saitou), chapters on rubbish or junk DNA (by Dan Graur), GC content heterogeneity (by Satoshi Oota), protein coding and RNA coding genes (by Tadashi Imanishi), duplicated genes (by Takashi Kitano), recombinations (by Montanucci and Bertranpetit), and copy number variations including microsatellites (by Naoko Takezaki) are discussed. Readers can obtain various new insights on the human genome from this part. In Part II, genes in X and Y chromosomes (by Yoko Satta and others), HLA genes (by Timothy A. Jinam), opsin genes (by Shoji Kawamura and Amanda D. Melin), genes related to phenotypic variations (by Ryosuke Kimura), transcription factors (by Mahoko Takahashi and So Nakagawa), diabetes-related genes (by Ituro Inoue), disease genes in general (by Ituro Inoue and Hirofumi Nakaoka), and microbial genomes (by Chaochun Wei) are discussed. The human genome sequences were determined in 2004, and after more than 10 years we are now beginning to understand the human genome from an evolutionary point of view. This book furnishes readers with a good summary of current research in the field.

Evolution of the Human Genome II

Evolution of the Human Genome II PDF Author: Naruya Saitou
Publisher: Springer Nature
ISBN: 4431569049
Category : Science
Languages : en
Pages : 264

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Book Description
This two-volume set provides a general overview of the evolution of the human genome; The first volume overviews the human genome with descriptions of important gene groups. This second volume provides up-to-date, concise yet ample knowledge on the genome evolution of modern humans. It comprises twelve chapters divided into two parts discussing “Non-neutral Evolution on Human Genes” (Part I) and “Evolution of Modern Human Populations” (Part II.) The most significant feature of this book is the continent-wise discussion of modern human dispersal using human genomic data in Part II. Recent results such as introgression of paleogenomes to modern humans, new methods such as computer simulation of global human dispersals, and new information on genes for humanness will be of particular interest to the readers. Since the euchromatin regions of the human genome was sequenced in 2003, a huge number of research papers were published on modern human evolution for a variety of populations. It is now time to summarize these achievements. This book stands out as the most comprehensive book on the modern human evolution, focusing on genomic points of view with a broad scope. Primary target audiences are researchers and graduate students in evolutionary biology.

Ancestors in Our Genome

Ancestors in Our Genome PDF Author: Eugene E. Harris (Professor)
Publisher:
ISBN: 0199978034
Category : Science
Languages : en
Pages : 249

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Book Description
In 2001, scientists were finally able to determine the full human genome sequence, and with the discovery began a genomic voyage back in time. Since then, we have sequenced the full genomes of a number of mankind's primate relatives at a remarkable rate. The genomes of the common chimpanzee (2005) and bonobo (2012), orangutan (2011), gorilla (2012), and macaque monkey (2007) have already been identified, and the determination of other primate genomes is well underway. Researchers are beginning to unravel our full genomic history, comparing it with closely related species to answer age-old questions about how and when we evolved. For the first time, we are finding our own ancestors in our genome and are thereby gleaning new information about our evolutionary past. In Ancestors in Our Genome, molecular anthropologist Eugene E. Harris presents us with a complete and up-to-date account of the evolution of the human genome and our species. Written from the perspective of population genetics, and in simple terms, the book traces human origins back to their source among our earliest human ancestors, and explains many of the most intriguing questions that genome scientists are currently working to answer. For example, what does the high level of discordance among the gene trees of humans and the African great apes tell us about our respective separations from our common ancestor? Was our separation from the apes fast or slow, and when and why did it occur? Where, when, and how did our modern species evolve? How do we search across genomes to find the genomic underpinnings of our large and complex brains and language abilities? How can we find the genomic bases for life at high altitudes, for lactose tolerance, resistance to disease, and for our different skin pigmentations? How and when did we interbreed with Neandertals and the recently discovered ancient Denisovans of Asia? Harris draws upon extensive experience researching primate evolution in order to deliver a lively and thorough history of human evolution. Ancestors in Our Genome is the most complete discussion of our current understanding of the human genome available.

Human Evolutionary Genetics

Human Evolutionary Genetics PDF Author: Mark Jobling
Publisher: Garland Science
ISBN: 1317952251
Category : Science
Languages : en
Pages : 1538

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Book Description
Human Evolutionary Genetics is a groundbreaking text which for the first time brings together molecular genetics and genomics to the study of the origins and movements of human populations. Starting with an overview of molecular genomics for the non-specialist (which can be a useful review for those with a more genetic background), the book shows h

Human Evolution

Human Evolution PDF Author: Graeme Finlay
Publisher: Cambridge University Press
ISBN: 1107040124
Category : Medical
Languages : en
Pages : 373

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Book Description
Brings together new research demonstrating how evidence based on genetic phenomena should end any lingering controversy over human evolution.

Principles of Evolutionary Medicine

Principles of Evolutionary Medicine PDF Author: Peter D. Gluckman
Publisher: Oxford University Press
ISBN: 0199663920
Category : Medical
Languages : en
Pages : 401

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Book Description
A new updated edition of the first integrated and comprehensive textbook to explain the principles of evolutionary biology from a medical perspective and to focus on how medicine and public health might utilise evolutionary biology.

Bones, Brains and DNA

Bones, Brains and DNA PDF Author: Ian Tattersall
Publisher: Bunker Hill Publishing, Inc.
ISBN: 9781593730567
Category : Juvenile Nonfiction
Languages : en
Pages : 60

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Book Description
Based on the New Hall of Human Origins in the American Museum of Natural History which opens in November 2006, Bones, Brains and DNA takes the young reader to the cutting edge of science, exploring and examining the tools by which we study our origins. Covering the milestones in evolution, global migration and how we became human through the invention of language, music, art and technology.

Molecular Biology of the Cell

Molecular Biology of the Cell PDF Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0

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Book Description


Gene Sharing and Evolution

Gene Sharing and Evolution PDF Author: Joram Piatigorsky
Publisher: Harvard University Press
ISBN: 9780674023413
Category : Science
Languages : en
Pages : 434

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Book Description
In Gene Sharing and Evolution Piatigorsky explores the generality and implications of gene sharing throughout evolution and argues that most if not all proteins perform a variety of functions in the same and in different species, and that this is a fundamental necessity for evolution.

Inside the Human Genome

Inside the Human Genome PDF Author: John C. Avise
Publisher: Oxford University Press
ISBN: 0190453079
Category : Science
Languages : en
Pages : 188

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Book Description
Humanity's physical design flaws have long been apparent--we get hemorrhoids and impacted wisdom teeth, for instance--but do the imperfections extend down to the level of our genes? Inside the Human Genome is the first book to examine the philosophical question of why, from the perspectives of biochemistry and molecular genetics, flaws exist in the biological world. Distinguished evolutionary geneticist John Avise offers a panoramic yet penetrating exploration of the many gross deficiencies in human DNA--ranging from mutational defects to built-in design faults--while at the same time offering a comprehensive treatment of recent findings about the human genome. The author shows that the overwhelming scientific evidence for genomic imperfection provides a compelling counterargument to intelligent design. He also develops a case that theologians should welcome rather than disavow these discoveries. The evolutionary sciences can help mainstream religions escape the shackles of Intelligent Design, and thereby return religion to its rightful realm--not as the secular interpreter of the biological minutiae of our physical existence, but rather as a respectable philosophical counselor on grander matters of ultimate concern.