Estimating Exposure to Dioxin-like Compounds

Estimating Exposure to Dioxin-like Compounds PDF Author:
Publisher:
ISBN:
Category : Dioxins
Languages : en
Pages : 696

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Estimating Exposure to Dioxin-like Compounds

Estimating Exposure to Dioxin-like Compounds PDF Author:
Publisher:
ISBN:
Category : Dioxins
Languages : en
Pages : 696

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Book Description


Estimating Exposure to Dioxin-like Compounds: Site-specific assessment procedures

Estimating Exposure to Dioxin-like Compounds: Site-specific assessment procedures PDF Author:
Publisher:
ISBN:
Category : Dioxins
Languages : en
Pages : 562

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Estimating Exposure to Dioxin-like Compounds: Executive summary

Estimating Exposure to Dioxin-like Compounds: Executive summary PDF Author:
Publisher:
ISBN:
Category : Dioxins
Languages : en
Pages : 136

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A Risk-Management Strategy for PCB-Contaminated Sediments

A Risk-Management Strategy for PCB-Contaminated Sediments PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309073219
Category : Political Science
Languages : en
Pages : 451

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Book Description
This book provides a risk-based framework for developing and implementing strategies to manage PCB-contaminated sediments at sites around the country. The framework has seven stages, beginning with problem definition, continuing through assessment of risks and management options, and ending with an evaluation of the success of the management strategy. At the center of the framework is continuous and active involvement of all affected parties-particularly communities-in the development, implementation, and evaluation of the management strategy. A Risk-Management Strategy for PCB-Contaminated Sediments emphasizes the need to consider all risks at a contaminated site, not just human health and ecological effects, but also the social, cultural, and economic impacts. Given the controversy that has arisen at many PCB-contaminated sites, this book provides a consistent, yet flexible, approach for dealing with the many issues associated with assessing and managing the risks at Superfund and other contaminated sites.

Veterans and Agent Orange

Veterans and Agent Orange PDF Author: Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides
Publisher: National Academies Press
ISBN: 9780309075299
Category : Medical
Languages : en
Pages : 791

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Book Description
Have U.S. military personnel experienced health problems from being exposed to Agent Orange, its dioxin contaminants, and other herbicides used in Vietnam? This definitive volume summarizes the strength of the evidence associating exposure during Vietnam service with cancer and other health effects and presents conclusions from an expert panel. Veterans and Agent Orange provides a historical review of the issue, examines studies of populations, in addition to Vietnam veterans, environmentally and occupationally exposed to herbicides and dioxin, and discusses problems in study methodology. The core of the book presents What is known about the toxicology of the herbicides used in greatest quantities in Vietnam. What is known about assessing exposure to herbicides and dioxin. What can be determined from the wide range of epidemiological studies conducted by different authorities. What is known about the relationship between exposure to herbicides and dioxin, and cancer, reproductive effects, neurobehavioral disorders, and other health effects. The book describes research areas of continuing concern and offers recommendations for further research on the health effects of Agent Orange exposure among Vietnam veterans. This volume will be critically important to both policymakers and physicians in the federal government, Vietnam veterans and their families, veterans organizations, researchers, and health professionals.

Pentachlorophenol and some related compounds

Pentachlorophenol and some related compounds PDF Author: International Agency for Research on Cancer
Publisher: International Agency for Research on Cancer
ISBN: 9789283201557
Category : Law
Languages : en
Pages : 0

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Book Description
This volume of the IARC Monographs provides evaluations of the carcinogenicity of pentachlorophenol, 2,4,6-trichlorophenol, 3,3',4,4'-tetrachloroazobenzene, aldrin, and dieldrin. Pentachlorophenol, aldrin, and dieldrin are classified as persistent organic pollutants under the Stockholm Convention. Pentachlorophenol has been widely used as a wood preservative and insecticide, but its production and use are now restricted. 2,4,6-Trichlorophenol has also been used as a wood preservative and insecticide, and in the synthesis of some fungicides. Aldrin and dieldrin are synthetic organochlorine pesticides used as broad-spectrum soil insecticides for the protection of various food crops, as seed dressings, and to control infestations of pests such as ants and termites. In several countries their use has been banned or severely restricted since the early 1970s. 3,3',4,4'-Tetrachloroazobenzene is not manufactured commercially but is formed during the production and degradation of chloroanilide herbicides such as propanil, linuron, and diuron. Exposure to all five agents considered may occur in the general population as well as in various occupational settings. An IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of environmental or occupational exposure of these agents.

Human and Environmental Risks of Chlorinated Dioxins and Related Compounds

Human and Environmental Risks of Chlorinated Dioxins and Related Compounds PDF Author: Richard E. Tucker
Publisher: Springer Science & Business Media
ISBN: 146133599X
Category : Science
Languages : en
Pages : 793

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Book Description
Increasing international concern is being expressed regarding the contamination of the environment with polychlorinated dibenzo-p dioxins (PCDDs) and polychlorinated dibenzofurans because certain of these chemicals have been shown to be highly toxic to animals and are ubiquitous in the environment. They are known to be distributed as contaminants of commercial products and as by-products from com bustion processes. A considerable volume of information has accumulated on these chemicals in the past two decades, particularly for the most toxic of them, 2,3,7,8-tetrach1orodibenzo-p-dioxin (2,3,7,8-TCDD). However, this body of knowledge has not succeeded in resolving genuine judgmental differences among experts in the field as to the degree of hazard to human health and the environment. In light of the widespread public concern, it is clearly imperative to come to grips with the continuing scientific controversy, to review the data, assess the issues, to see where areas of agreement exist, and where further research is needed to resolve remaining areas of disagree ment. This volume represents an effort to contribute to these goals.

Systems Biology in Toxicology and Environmental Health

Systems Biology in Toxicology and Environmental Health PDF Author: Rebecca Fry
Publisher: Academic Press
ISBN: 0128015683
Category : Medical
Languages : en
Pages : 285

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Book Description
Systems Biology in Toxicology and Environmental Health uses a systems biological perspective to detail the most recent findings that link environmental exposures to human disease, providing an overview of molecular pathways that are essential for cellular survival after exposure to environmental toxicants, recent findings on gene-environment interactions influencing environmental agent-induced diseases, and the development of computational methods to predict susceptibility to environmental agents. Introductory chapters on molecular and cellular biology, toxicology and computational biology are included as well as an assessment of systems-based tools used to evaluate environmental health risks. Further topics include research on environmental toxicants relevant to human health and disease, various high-throughput technologies and computational methods, along with descriptions of the biological pathways associated with disease and the developmental origins of disease as they relate to environmental contaminants. Systems Biology in Toxicology and Environmental Health is an essential reference for undergraduate students, graduate students, and researchers looking for an introduction in the use of systems biology approaches to assess environmental exposures and their impacts on human health. - Provides the first reference of its kind, demonstrating the application of systems biology in environmental health and toxicology - Includes introductions to the diverse fields of molecular and cellular biology, toxicology, and computational biology - Presents a foundation that helps users understand the connections between the environment and health effects, and the biological mechanisms that link them

Provisional Guidance for Quantitative Risk Assessment of Polycyclic Aromatic Hydrocarbons

Provisional Guidance for Quantitative Risk Assessment of Polycyclic Aromatic Hydrocarbons PDF Author:
Publisher:
ISBN:
Category : Health risk assessment
Languages : en
Pages : 28

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Mixture Toxicity

Mixture Toxicity PDF Author: Cornelis A. M. van Gestel
Publisher: CRC Press
ISBN: 1439830096
Category : Medical
Languages : en
Pages : 312

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Book Description
In the last decade and a half, great progress has been made in the development of concepts and models for mixture toxicity, both in human and environmental toxicology. However, due to their different protection goals, developments have often progressed in parallel but with little integration. Arguably the first book to clearly link ecotoxicology an