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Author: Lynda H. Powell
Publisher: Springer Nature
ISBN: 3030393305
Category : Psychology
Languages : en
Pages : 324
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Book Description
This is the first comprehensive guide to the design of behavioral randomized clinical trials (RCT) for chronic diseases. It includes the scientific foundations for behavioral trial methods, problems that have been encountered in past behavioral trials, advances in design that have evolved, and promising trends and opportunities for the future. The value of this book lies in its potential to foster an ability to “speak the language of medicine” through the conduct of high-quality behavioral clinical trials that match the rigor commonly seen in double-blind drug trials. It is relevant for testing any treatment aimed at improving a behavioral, social, psychosocial, environmental, or policy-level risk factor for a chronic disease including, for example, obesity, sedentary behavior, adherence to treatment, psychosocial stress, food deserts, and fragmented care. Outcomes of interest are those that are of clinical significance in the treatment of chronic diseases, including standard risk factors such as cholesterol, blood pressure, and glucose, and clinical outcomes such as hospitalizations, functional limitations, excess morbidity, quality of life, and mortality. This link between behavior and chronic disease requires innovative clinical trial methods not only from the behavioral sciences but also from medicine, epidemiology, and biostatistics. This integration does not exist in any current book, or in any training program, in either the behavioral sciences or medicine.
Author: Lynda H. Powell
Publisher: Springer Nature
ISBN: 3030393305
Category : Psychology
Languages : en
Pages : 324
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Book Description
This is the first comprehensive guide to the design of behavioral randomized clinical trials (RCT) for chronic diseases. It includes the scientific foundations for behavioral trial methods, problems that have been encountered in past behavioral trials, advances in design that have evolved, and promising trends and opportunities for the future. The value of this book lies in its potential to foster an ability to “speak the language of medicine” through the conduct of high-quality behavioral clinical trials that match the rigor commonly seen in double-blind drug trials. It is relevant for testing any treatment aimed at improving a behavioral, social, psychosocial, environmental, or policy-level risk factor for a chronic disease including, for example, obesity, sedentary behavior, adherence to treatment, psychosocial stress, food deserts, and fragmented care. Outcomes of interest are those that are of clinical significance in the treatment of chronic diseases, including standard risk factors such as cholesterol, blood pressure, and glucose, and clinical outcomes such as hospitalizations, functional limitations, excess morbidity, quality of life, and mortality. This link between behavior and chronic disease requires innovative clinical trial methods not only from the behavioral sciences but also from medicine, epidemiology, and biostatistics. This integration does not exist in any current book, or in any training program, in either the behavioral sciences or medicine.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309255716
Category : Medical
Languages : en
Pages : 424
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Book Description
In the late 1980s, the National Cancer Institute initiated an investigation of cancer risks in populations near 52 commercial nuclear power plants and 10 Department of Energy nuclear facilities (including research and nuclear weapons production facilities and one reprocessing plant) in the United States. The results of the NCI investigation were used a primary resource for communicating with the public about the cancer risks near the nuclear facilities. However, this study is now over 20 years old. The U.S. Nuclear Regulatory Commission requested that the National Academy of Sciences provide an updated assessment of cancer risks in populations near USNRC-licensed nuclear facilities that utilize or process uranium for the production of electricity. Analysis of Cancer Risks in Populations near Nuclear Facilities: Phase 1 focuses on identifying scientifically sound approaches for carrying out an assessment of cancer risks associated with living near a nuclear facility, judgments about the strengths and weaknesses of various statistical power, ability to assess potential confounding factors, possible biases, and required effort. The results from this Phase 1 study will be used to inform the design of cancer risk assessment, which will be carried out in Phase 2. This report is beneficial for the general public, communities near nuclear facilities, stakeholders, healthcare providers, policy makers, state and local officials, community leaders, and the media.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309036879
Category : Nature
Languages : en
Pages : 476
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Book Description
The most recent volume in the Drinking Water and Health series contains the results of a two-part study on the toxicity of drinking water contaminants. The first part examines current practices in risk assessment, identifies new noncancerous toxic responses to chemicals found in drinking water, and discusses the use of pharmacokinetic data to estimate the delivered dose and response. The second part of the book provides risk assessments for 14 specific compounds, 9 presented here for the first time.
Author: Alex Mercer
Publisher: Boydell & Brewer
ISBN: 1580465080
Category : Medical
Languages : en
Pages : 353
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Book Description
In 1949 the U.S. National Cancer Institute (NCI) and the Canadian Department of National Health and Welfare (DNHW) commissioned a film, eventually called Challenge. Science Against Cancer, as part of a major effort to recruit young scientists into cancer research. Both organizations feared that poor recruitment would stifle the development of the field at a time when funding for research was growing dramatically. The fear was that there would not be enough new young scientists to meet the demand, and that the shortfall would undermine cancer research and the hopes invested in it. Challenge aimed to persuade young scientists to think of cancer research as a career. This book is the story of that forgotten film and what it tells us about mid-twentieth century American and Canadian cancer research, educational filmmaking, and health education campaigns. It explores why Canadian and American health agencies turned to film to address the problem of scientist recruitment; how filmmakers turned such recruitment concerns into something they thought would work as a film; and how information officers at the NCI and DNHW sought to shape the impact of Challenge by embedding it in a broader educational and propaganda program. It is, in short, an account of the important, but hitherto undocumented, roles of filmmakers and information officers in the promotion of post-Second World War cancer research.
Author: Diana Kuh
Publisher: Oxford University Press
ISBN: 9780198578154
Category : Medical
Languages : en
Pages : 500
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Book Description
From reviews of the previous edition:'We still have much to learn if disease patterns are to be explained by taking a life course approach... this book provides strong arguments for this approach... the book is a highly qualified starting point for the debate... it will remain a useful summary of pioneer research of huge potential importance for public health.' -Epidemiology'This is not just another epidemiology textbook. It is essential reading for anyone with an active mind who is interested in public health.' -Journal of Public Health Medicine'A truly exciting and extremely informative endeavour for anyone interested in the determinants of human health and disease. This discussion is at the core of current public health issues.' -European Journal of Public Health'The conclusion is of major importance to public health policy. It reinforces the need for a life course strategy, with attention being paid to the mother, baby, child adolescent, and elderly person.' -BMJ'Provokes thought about the origins of chronic diseases, suggests new approaches to identifying particular susceptible individuals and encourages the identification of optimal points in the life course for possible preventive interventions.' -Chronic Diseases in CanadaThe first edition in 1997 of A life course approach to chronic disease epidemiology became a classic text for epidemiological and public health researchers interested in the childhood origins of adult chronic disease. Since then the new field of life course epidemiology has expanded rapidly, attracting the interest not only of academics across the health and social sciences but also policy makers, funding bodies, and the general public. Its purpose is to study how biological and social factors during gestation, childhood, adolescence and earlier adult life independently, cumulatively and interactively influence later life health and disease.Contributors to this fully revised second edition capture the excitement of the developing field and assess the latest evidence regarding sources of risk to health across the life course and across generations. The original chapters on life course influences on cardiovascular disease, diabetes, blood pressure, respiratory disease and cancer have been updated and extended. New chapters on life course influences on obesity, biological ageing and neuropsychiatric disorders have been added. Life course explanations for disease trends and for socioeconomic differentials in disease risk are given more attention in this new edition, reflecting recent developments in the field. The section on policy implications has been expanded, assessing the role of interventions to improve childhood social circumstances, as well as interventions to improve early growth. Emerging new research themes and the theoretical and methodological challenges facing life course epidemiology are highlighted.Readership: Epidemiologists, public health researchers, public health policy makers for developed and developing countries, sociologists and biologists, psychiatrists and social and chronic disease epidemiologists
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309165911
Category : Medical
Languages : en
Pages : 234
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Book Description
In recent years, a number of chronic diseases have been linked, in some cases definitively, to an infectious etiology: peptic ulcer disease with Helicobacter pylori, cervical cancer with several human papillomaviruses, Lyme arthritis and neuroborreliosis with Borrelia burgdorferi, AIDS with the human immunodeficiency virus, liver cancer and cirrhosis with hepatitis B and C viruses, to name a few. The proven and suspected roles of microbes does not stop with physical ailments; infections are increasingly being examined as associated causes of or possible contributors to a variety of serious, chronic neuropsychiatric disorders and to developmental problems, especially in children. The Infectious Etiology of Chronic Diseases: Defining the Relationship, Enhancing the Research, and Mitigating the Effects, summarizes a two-day workshop held by the Institute of Medicine's Forum on Microbial Threats to address this rapidly evolving field. Participants explored factors driving infectious etiologies of chronic diseases of prominence, identified difficulties in linking infectious agents with chronic outcomes, and discussed broad-based strategies and research programs to advance the field.
Author: George Weisz
Publisher: JHU Press
ISBN: 1421413027
Category : Law
Languages : en
Pages : 326
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Book Description
Chronic Disease in the Twentieth Century challenges the conventional wisdom that the concept of chronic disease emerged because medicine's ability to cure infectious disease led to changing patterns of disease. Instead, it suggests, the concept was constructed and has evolved to serve a variety of political and social purposes. How and why the concept developed differently in the United States, an United Kingdom, and France are central concerns of this work. While an international consensus now exists, the different paths taken by these three countries continue to exert profound influence. This book seeks to explain why, among the innumerable problems faced by societies, some problems in some places become viewed as critical public issues that shape health policy. -- from back cover.
Author: Peter Croft
Publisher: Oxford University Press, USA
ISBN: 0199235767
Category : Medical
Languages : en
Pages : 377
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Book Description
This book provides an invaluable framework and basis for thinking about chronic pain and the potential for its prevention in public health terms.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309039940
Category : Medical
Languages : en
Pages : 765
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Book Description
Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309124999
Category : Computers
Languages : en
Pages : 334
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Book Description
In the realm of health care, privacy protections are needed to preserve patients' dignity and prevent possible harms. Ten years ago, to address these concerns as well as set guidelines for ethical health research, Congress called for a set of federal standards now known as the HIPAA Privacy Rule. In its 2009 report, Beyond the HIPAA Privacy Rule: Enhancing Privacy, Improving Health Through Research, the Institute of Medicine's Committee on Health Research and the Privacy of Health Information concludes that the HIPAA Privacy Rule does not protect privacy as well as it should, and that it impedes important health research.
