Endemic Cretinism

Endemic Cretinism PDF Author: John Dennison
Publisher: Springer Science & Business Media
ISBN: 1461402816
Category : Medical
Languages : en
Pages : 225

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Book Description
Responding to a renewed interest in the growing problem of iodine deficiency worldwide, Drs. Charles Oxnard and Peter Obendorf, along with experienced translator and anatomist John Dennison, take a fresh look at the classic text, Der endemische Kretinismus, published in 1936 by Springer. Translated here for the first time into English, this landmark text will be a welcome resource for researchers confronting the problem of iodine deficiency. Oxnard and Obendorf point out that there is very little detailed knowledge or numerical data on cretinism available in the English-speaking world. In addition, highly-renowned Professor Basil S. Hetzel, recently-retired World Health Organization Chairman of the International Council for Control of Iodine Deficiency Disorders, published in 2009 with Dr Chen Zu-pei on the resurgence of iodine deficiency in China. Indeed, throughout the entire developing world there may be as many as two billion people at risk to iodine deficiency; perhaps three quarters of a billion have goiter, and ten million may be cretins. Even in developed countries, iodine deficiency is re-emerging (as in New South Wales in 19% of children) with the result of significantly reduced numbers of gifted children (though this is not cretinism per se). Certain to be of significant interest to a wide range of researchers, health providers and professionals, including government health administrators, this English translation of Endemic Cretinism is a major contribution to the literature.

Endemic Cretinism

Endemic Cretinism PDF Author: John Dennison
Publisher: Springer Science & Business Media
ISBN: 1461402816
Category : Medical
Languages : en
Pages : 225

Get Book

Book Description
Responding to a renewed interest in the growing problem of iodine deficiency worldwide, Drs. Charles Oxnard and Peter Obendorf, along with experienced translator and anatomist John Dennison, take a fresh look at the classic text, Der endemische Kretinismus, published in 1936 by Springer. Translated here for the first time into English, this landmark text will be a welcome resource for researchers confronting the problem of iodine deficiency. Oxnard and Obendorf point out that there is very little detailed knowledge or numerical data on cretinism available in the English-speaking world. In addition, highly-renowned Professor Basil S. Hetzel, recently-retired World Health Organization Chairman of the International Council for Control of Iodine Deficiency Disorders, published in 2009 with Dr Chen Zu-pei on the resurgence of iodine deficiency in China. Indeed, throughout the entire developing world there may be as many as two billion people at risk to iodine deficiency; perhaps three quarters of a billion have goiter, and ten million may be cretins. Even in developed countries, iodine deficiency is re-emerging (as in New South Wales in 19% of children) with the result of significantly reduced numbers of gifted children (though this is not cretinism per se). Certain to be of significant interest to a wide range of researchers, health providers and professionals, including government health administrators, this English translation of Endemic Cretinism is a major contribution to the literature.

Iodine and the Brain

Iodine and the Brain PDF Author: G. Robert Delong
Publisher: Springer Science & Business Media
ISBN: 1461307651
Category : Medical
Languages : en
Pages : 376

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Book Description
This volume contains the proceedings of a conference held at the National Institutes of Health in Bethesda on March 21-23. 1988. jointly sponsored by the International Council for Control of Iodine Deficiency Disorders (ICCIDD) and the Fogarty International Center of the National Institutes of Health. Several themes converged to make this meeting timely. The first is an increasing awareness of iodine deficiency disorders as a world-wide problem of public health and a preventable cause of mental deficiency. and as a subject of scientific effort. Increased interest in these problems owes a great deal to accessibility to remote and under developed areas of the world where iodine deficiency persists. As with any subject. greater scrutiny yields unexpected complexity and interest. It is true that provision of iodine. typically as iodized salt, is the necessary and sufficient preventative for iodine deficiency disorders. without including endemic cretinism. This provision is a governmental, economic and social problem. Apart from this, however, the scientific and medical problem of iodine deficiency and its effect on brain development and function is one of great interest and importance for developmental neurology and psychology. Even though the specific preventative agent is known, we do not totally understand the neurobiological questions raised.

History and Iconography of Endemic Goitre and Cretinism

History and Iconography of Endemic Goitre and Cretinism PDF Author: F. Merke
Publisher: Springer
ISBN:
Category : Medical
Languages : en
Pages : 360

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Book Description


Endemic Cretinism

Endemic Cretinism PDF Author: Basil S. Hetzel
Publisher:
ISBN:
Category : Congenial hypothyrodism
Languages : en
Pages : 150

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Book Description


Clinical Management of Thyroid Disease E-Book

Clinical Management of Thyroid Disease E-Book PDF Author: Fredric E. Wondisford
Publisher: Elsevier Health Sciences
ISBN: 1437719694
Category : Medical
Languages : en
Pages : 435

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Book Description
Clinical Management of Thyroid Disease is an exciting new book edited by Fredric Wondisford, MD—developer of the revolutionary new drug, Thyrotropin—and Sally Radovick, MD, with contributions from experts in the field. It fulfills the niche of a succinct, clinical resource to help you translate research into practice. This full-color volume offers valuable information on thyroid cancer and non-cancerous lesions, the effect of drugs on thyroid function, genetic disorders, and more in an accessible, easy-to-read consistent format. Presents the expertise of authors and editorial staff comprised of leaders in the field of thyroid research and clinical management for the best-qualified guidance on diagnosis and treatment. Provides a full-color, comprehensive approach that makes valuable information easy to locate and quick to read. Covers relevant topics applicable to all levels of training and expertise to serve as a detailed clinical reference on everything from the basic to the sophisticated. Captures research advances on hot topics such as thyroid cancer and non-cancerous lesions, the effect of drugs on thyroid function, and genetic disorders so that you can incorporate them into the way you treat patients.

Trace Minerals in Foods

Trace Minerals in Foods PDF Author: K. Smith
Publisher: CRC Press
ISBN: 9780824778354
Category : Technology & Engineering
Languages : en
Pages : 250

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Book Description
Twelve contributions evaluate the chemistry of trace elements in preparations and their potential bioavailability to the consumer; consider palatability, mineral interactions, and other nutritional factors; discuss trace elements' biology and pharmacokinetics to facilitate the development of protoco

Towards the Eradication of Endemic Goiter, Cretinism, and Iodine Deficiency

Towards the Eradication of Endemic Goiter, Cretinism, and Iodine Deficiency PDF Author: PAHO/WHO Technical Group on Endemic Goiter, Cretinism, and Iodine Deficiency. Meeting
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 448

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Book Description
This book presents the scientific papers, discussions, and recommendations of the 1983 Lima, Peru PAHO/WHO Technical Group Meeting. The text is divided into 5 parts, examining the various topics in the subjects (pathophysiology, special problems, methods of diagnosis and treatment, geographic documentation, and recommendations.

70 Years of Levothyroxine

70 Years of Levothyroxine PDF Author: George J. Kahaly
Publisher: Springer Nature
ISBN: 3030632776
Category : Medical
Languages : en
Pages : 141

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Book Description
This open access book presents the history, pharmacokinetics and pharmacodynamics of levothyroxine, discussing its role in the thyroid pathophysiology of patients of various ages and during pregnancy. It also describes the influence of levothyroxine on heart, bone and in cancer. When it was first synthesized in 1949, levothyroxine represented a significant advance in the treatment of hypothyroidism, providing a safe and effective treatment option for millions of hypothyroid patients around the globe. This synthetic form of thyroxine is now one of the most prescribed drugs in the world. Levothyroxine was first introduced by Merck KGaA,Darmstadt, Germany, in 1972, and since then the company has remained actively engaged in research on this mainstay of hypothyroidism treatment. This book is intended for healthcare professionals.

Comprehensive Handbook of Iodine

Comprehensive Handbook of Iodine PDF Author: Victor R. Preedy
Publisher: Academic Press
ISBN: 9780080920863
Category : Technology & Engineering
Languages : en
Pages : 1334

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Book Description
Over two billion people worldwide are at risk for the spectrum of disorders known as "The Iodine Deficiency Disorders." 1-10% will suffer cretinism; 5-30% will have some sort of brain damage or neurological impairment and 30-70% will be hypothyroid. The causes of iodine deficiencies can be considered from both simplistic and more complex perspectives: From the leaching of iodine from soil resulting in crops with low iodine content to malnutrition resulting in impaired iodine absorption. Poor dietary diversification and impoverished socio-economic development can also lead to iodine deficiencies. Although it is possible to diagnose and treat deficiencies, there is still an ongoing dialogue regarding the detailed molecular pathology of iodine homeostatis, how hypothyroidism impacts the body tissues, and efficient diagnosis and treatment of the Iodine Deficiency Disorders. This Handbook provides a resource of information on the various pathways and processes based on different countries or diseases. Because there is a constant flow of new information on iodine and related disorders, the goal of this Handbook is to provide a base of scientific information upon which additional knowledge can be applied. Provides important information on one of the most common micro-nutrient deficiencies in the world, the most important "single nutrient-multiple consequences" paradigm today Includes information on iodine-related diseases, including those that are common, preventable and treatable Provides insight from a broad perspective of viewpoints -- from subcellular transports to economic impact

Molecular Basis of Nutrition and Aging

Molecular Basis of Nutrition and Aging PDF Author: Marco Malavolta
Publisher: Academic Press
ISBN: 0128018275
Category : Science
Languages : en
Pages : 784

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Book Description
Molecular Basis of Nutrition and Aging: A Volume in the Molecular Nutrition Series focuses on the nutritional issues associated with aging and the important metabolic consequences of diet, nutrition, and health. The book is subdivided into four parts that reflect the impact of nutrition from a biomolecular level to individual health. In Part One, chapters explore the general aspects of aging, aging phenotypes, and relevant aspects of nutrition related to the elderly and healthy aging. Part Two includes molecular and cellular targets of nutrition in aging, with chapters exploring lipid peroxidation, inflammaging, anabolic and catabolic signaling, epigenetics, DNA damage and repair, redox homeostasis, and insulin sensitivity, among others. Part Three looks at system-level and organ targets of nutrition in aging, including a variety of tissues, systems, and diseases, such as immune function, the cardiovascular system, the brain and dementia, muscle, bone, lung, and many others. Finally, Part Four focuses on the health effects of specific dietary compounds and dietary interventions in aging, including vitamin D, retinol, curcumin, folate, iron, potassium, calcium, magnesium, zinc, copper, selenium, iodine, vitamin B, fish oil, vitamin E, resveratrol, polyphenols, vegetables, and fruit, as well as the current nutritional recommendations. Offers updated information and a perspectives on important future developments to different professionals involved in the basic and clinical research on all major nutritional aspects of aging Explores how nutritional factors are involved in the pathogenesis of aging across body systems Investigates the molecular and genetic basis of aging and cellular senescence through the lens of the rapidly evolving field of molecular nutrition