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Author: Zoltan Molnar
Publisher: Springer
ISBN: 9783540642251
Category : Medical
Languages : en
Pages : 262
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Book Description
This book addresses the current debate on the areal specialization of the cerebral cortex, with a detailed examination of the interactions between the developing thalamus and cerebral cortex. It discusses recent in vivo and in vitro approaches and how they reveal possible guiding mechanisms involved in the deployment of the thalamocortical fibers and the earliest interactions between the new thalamic fibers and the developing cortical circuitry. It also presents new views on the possible evolutionary origin of the developmental algorithms employed during thalamocortical development.
Author: Zoltan Molnar
Publisher: Springer
ISBN: 9783540642251
Category : Medical
Languages : en
Pages : 262
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Book Description
This book addresses the current debate on the areal specialization of the cerebral cortex, with a detailed examination of the interactions between the developing thalamus and cerebral cortex. It discusses recent in vivo and in vitro approaches and how they reveal possible guiding mechanisms involved in the deployment of the thalamocortical fibers and the earliest interactions between the new thalamic fibers and the developing cortical circuitry. It also presents new views on the possible evolutionary origin of the developmental algorithms employed during thalamocortical development.
Author: Zoltán Molnár
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 290
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Book Description
Author: Zoltan Molnar
Publisher: International Thomson Publishing Services
ISBN: 9780412140914
Category : Science
Languages : en
Pages : 200
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Book Description
Author: Daniel Blakey
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Gordon M. Shepherd
Publisher: Oxford University Press
ISBN: 0190636114
Category : Medical
Languages : en
Pages : 625
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Book Description
In order to focus on principles, each chapter in this work is brief, organized around 1-3 wiring diagrams of the key circuits, with several pages of text that distil the functional significance of each microcircuit
Author: S. Murray Sherman
Publisher: MIT Press
ISBN: 0262315009
Category : Science
Languages : en
Pages : 299
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Book Description
Two leading authorities on thalamocortical connections consider how the neural circuits of the brain relate to our actions and perceptions. In this book, two leading authorities on the thalamus and its relationship to cortex build on their earlier findings to arrive at new ways of thinking about how the brain relates to the world, to cognition, and behavior. Based on foundations established earlier in their book Exploring the Thalamus and Its Role in Cortical Function, the authors consider the implications of these ground rules for thalamic inputs, thalamocortical connections, and cortical outputs. The authors argue that functional and structural analyses of pathways connecting thalamus and cortex point beyond these to lower centers and through them to the body and the world. Each cortical area depends on the messages linking it to body and world. These messages relate to the way we act and think; each cortical area receives thalamic inputs and has outputs to motor centers. Sherman and Guillery go on to discuss such topics as the role of branching axons that carry motor instructions as well as copies of these motor instructions for relay to cortex under the control of the thalamic gate. This gate allows the thalamus to control the passage of information on the basis of which cortex relates to the rest of the nervous system.
Author: Reha Erzurumlu
Publisher: Springer Science & Business Media
ISBN: 0387386076
Category : Medical
Languages : en
Pages : 336
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Book Description
This volume provides an update on the multitude of technical and experimental approaches in understanding the development and plasticity of the mammalian sensory thalamus and neocortex. The focus is on visual and somatosensory thalamus and neocortex in rodents and carnivores, and functional imaging studies in developing and aging human neocortex. It further provides a synthetic theoretical framework for future studies.
Author: Aarti Nair
Publisher:
ISBN: 9781321928600
Category : Autism spectrum disorders in children
Languages : en
Pages : 74
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Book Description
Rationale : The present dissertation project specifically sought to understand brain networks connecting with the thalamus, an important subcortical relay structure through which almost all sensory information is routed. In view of the known fundamental importance of thalamocortical connectivity for the development of regional functional specialization in cerebral cortex, it is surprising how little firm knowledge is available about the thalamus and its connections with cortex in Autism Spectrum Disorders (ASD). Therefore, it is crucial to examine the role of the thalamus in regulating these functions for an improved understanding of neurodevelopmental mechanisms associated with ASD. Design : The first study of this project examined functional and anatomical connectivity between five broad cortical regions of interests (ROIs; e.g., temporal lobes) and the thalamus for a sample of children and adolescents with ASD (N=26) compared to TD controls (N=27). This first study allowed us to broadly characterize the connectivity between ipsilateral thalamus and the different lobes. In the second study, we delved deeper into the specificity of connections between more narrowly specialized regions (e.g., fusiform gyrus or anterior temporal pole) and the thalamus for a larger sample of children and adolescents with ASD (N=37) compared to TD controls (N=38). Results : In the first study, we found evidence of both anatomical and functional underconnectivity between the prefrontal, parietal-occipital, motor, and somatosensory cortices with ipsilateral thalamus. The only exception was functional connectivity with the temporal lobe, which was increased in the ASD group, especially in the right hemisphere. Delving deeper into the specificity of these connections in the second study, we found that functional connectivity was atypically reduced in the ASD group for supramodal association cortices involved in higher-order cognition (e.g., language, face processing), but was increased for sensorimotor and limbic regions (e.g., auditory cortex). Discussions : Our findings provide evidence of regionally specific aberrations of thalamic connectivity in frontal and temporal lobes, with additional involvement of some parieto-occipital ROIs. These findings could be related to early maturation of limbic and sensorimotor regions in the context of early overgrowth in ASD, at the expense of thalamocortical connectivity with later maturing cortical regions.
Author: Dean C.. Delis
Publisher:
ISBN: 9780158091310
Category : Cognition
Languages : en
Pages : 388
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Book Description
Author: Ryoichiro Kageyama
Publisher: Springer Science & Business Media
ISBN: 4431544968
Category : Medical
Languages : en
Pages : 283
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Book Description
This book reviews recent progress in cortical development research, focusing on the mechanisms of neural stem cell regulation, neuronal diversity and connectivity formation, and neocortical organization. Development of the cerebral cortex, the center for higher brain functions such as cognition, memory, and decision making, is one of the major targets of current research. The cerebral cortex is divided into many areas, including motor, sensory, and visual cortices, each of which consists of six layers containing a variety of neurons with different activities and connections. As this book explains, such diversity in neuronal types and connections is generated at various levels. First, neural stem cells change their competency over time, giving sequential rise to distinct types of neurons and glial cells: initially deep layer neurons, then superficial layer neurons, and lastly astrocytes. The activities and connections of neurons are further modulated via interactions with other brain regions, such as the thalamocortical circuit, and via input from the environment. This book on cortical development is essential reading for students, postdocs, and neurobiologists.
