Development of Micro/nanobubbles for Theranostic Applications

Development of Micro/nanobubbles for Theranostic Applications PDF Author: Ruyuan Song
Publisher:
ISBN:
Category :
Languages : en
Pages : 127

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Book Description

Development of Micro/nanobubbles for Theranostic Applications

Development of Micro/nanobubbles for Theranostic Applications PDF Author: Ruyuan Song
Publisher:
ISBN:
Category :
Languages : en
Pages : 127

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Book Description


Micro- and Nanobubbles

Micro- and Nanobubbles PDF Author: Hideki Tsuge
Publisher: CRC Press
ISBN: 9814463108
Category : Medical
Languages : en
Pages : 378

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Book Description
Microbubbles and nanobubbles have several characteristics that are comparable with millimeter- and centimeter-sized bubbles. These characteristics are their small size, which results in large surface area and high bioactivity, low rising velocity, decreased friction drag, high internal pressure, large gas dissolution capacity, negatively charged surface, and ability to be crushed and form free radicals. Microbubbles and nanobubbles have found applications in a variety of fields such as engineering, agriculture, environment, food, and medicine. Microbubbles have been successfully used in aquacultures of oysters in Hiroshima, scallops in Hokkaido, and pearls in Mie Prefecture, Japan. This field has shown a strong potential for growth. This book comprehensively discusses microbubbles and nanobubbles and their application in aquaculture, environment, engineering, medicine, stock raising, agriculture, and marine industry. It presents their potential as a new technology that can be utilized globally.

Advances in Functional Micro-/Nanoimaging Probes

Advances in Functional Micro-/Nanoimaging Probes PDF Author: Zhe Liu
Publisher: Springer
ISBN: 9811048045
Category : Technology & Engineering
Languages : en
Pages : 136

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Book Description
This book highlights the latest advances in functional micro/nano imaging probes and their applications for biomedical imaging and therapy. Given the rapid emergence of transdisciplinary research and applications in materials, chemical probes and translational medicine in recent years, scientists in these areas are expected to keep up to date on the latest technologies and advances to promote comprehensive innovations. Addressing this need, the book presents recently introduced features, emerging techniques, and new strategies, complemented by detailed illustrations. Covering the status quo and offering an outlook on the future, it benefits all readers with an interest in functional materials, especially micro/nano imaging materials for biomedical imaging applications, providing them with both vital updates and inspiration for their own research.

Ultrafine Bubbles

Ultrafine Bubbles PDF Author: Koichi Terasaka
Publisher: CRC Press
ISBN: 1000333639
Category : Science
Languages : en
Pages : 294

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Book Description
Ultrafine bubbles (UFBs) are gas-filled bubbles with a diameter smaller than 1 μm. They are sometimes called bulk nanobubbles because these are not on a solid surface but inside a bulk liquid (water). They are already being used in commercial processes such as cleaning and plant cultivation. However, many mysteries still exist with respect to UFBs, such as mechanisms of stability, OH radical formation, and biological and medical effects. This is the first book on UFBs that reviews research done on them. It is helpful for those interested in the fundamentals of this emerging field and its applications, including cleaning, biological, medical, and dental students and researchers.

Applications of Nanoscience in Photomedicine

Applications of Nanoscience in Photomedicine PDF Author: Michael R. Hamblin
Publisher: Elsevier
ISBN: 1908818786
Category : Science
Languages : en
Pages : 573

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Book Description
Nanoscience has become one of the key growth areas in recent years. It can be integrated into imaging and therapy to increase the potential for novel applications in the field of photomedicine. In the past commercial applications of nanoscience have been limited to materials science research only, however, in recent years nanoparticles are rapidly being incorporated into industrial and consumer products. This is mainly due to the expansion of biomedical related research and the burgeoning field of nanomedicine. Applications of Nanoscience in Photomedicine covers a wide range of nanomaterials including nanoparticles used for drug delivery and other emerging fields such as optofluidics, imaging and SERS diagnostics. Introductory chapters are followed by a section largely concerned with imaging, and finally a section on nanoscience-enabled therapeutics. - Covers a comprehensive up-to-date information on nanoscience - Focuses on the combination of photomedicine with nanotechnology to enhance the diversity of applications - Pioneers in the field have written their respective chapters - Opens a plethora of possibilities for developing future nanomedicine - Easy to understand and yet intensive coverage chapter by chapter

Bionanotechnology in Cancer

Bionanotechnology in Cancer PDF Author: D. Sakthi Kumar
Publisher: CRC Press
ISBN: 0429750412
Category : Medical
Languages : en
Pages : 679

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Book Description
The cancer research world is looking forward to bionanotechnology to find the best solutions for a complete cure from cancer, which is not possible with the current established treatment methods. The past decade of research on nano imaging and drug delivery in cancer has witnessed many interesting papers and reviews, but there has not been a concise resource that discusses all fields related to nano cancer research in diagnosis and drug delivery. This book fills this gap and presents the latest bionano research in cancer, focusing on nanodiagnostics and nanotherapy. The book is organized into two sections. The section on nanodiagnostics focuses on topics such as diagnostic methods in cancer-related therapy and use of radiolabeled nanoparticles, magnetic nanoparticles, acoustically reflective nanoparticles, X-ray computed tomography, and optical nanoprobes for diagnosis. The section on nanotherapy focuses on nanomaterials in chemotherapy, magnetic nanoparticles for hyperthermia against cancer, phototherapy, nanotechnology-mediated radiation therapy, nanoparticle-mediated small-RNA deliveries for molecular therapies, and theranostics. The book will serve as the gateway to enter the beautiful and elegant field of bionanoscience, which is considered the last hope for the fight against cancer and will be a highly useful resource for the students, researchers, teachers, and curious readers working in this field or related fields.

Nanotheranostics for Cancer Applications

Nanotheranostics for Cancer Applications PDF Author: Prakash Rai
Publisher: Springer
ISBN: 3030017753
Category : Technology & Engineering
Languages : en
Pages : 484

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Book Description
This book is the first to focus specifically on cancer nanotheranostics. Each of the chapters that make up this comprehensive volume is authored by a researcher, clinician, or regulatory agency member known for their expertise in this field. Theranostics, the technology to simultaneously diagnose and treat a disease, is a nascent field that is growing rapidly in this era of personalized medicine. As the need for cost-effective disease diagnosis grows, drug delivery systems that can act as multifunctional carriers for imaging contrast and therapy agents could provide unique breakthroughs in oncology. Nanotechnology has enabled the development of smart theranostic platforms that can concurrently diagnose disease, start primary treatment, monitor response and initiate secondary treatments if required. In oncology, chemotherapeutics have been routinely used. Some drugs have proven effective but all carry risks of adverse side effects. There is growing interest in using remotely triggered drug delivery systems to limit cytotoxicity in the diseased area. This book reviews the use of theranostic nanoparticles for cancer applications over the past decade. First, it briefly discusses the challenges and limitations of conventional cancer treatments, and presents an overview of the use of nanotechnology in treating cancer. These introductory chapters are followed by those exploring cancer diagnosis and a myriad of delivery methods for nanotherapeutics. The book also addresses multifunctional platforms, treatment monitoring, and regulatory considerations. As a whole, the book aims to briefly summarize the development and clinical potential of various nanotheranostics for cancer applications, and to delineate the challenges that must be overcome for successful clinical development and implementation of such cancer theranostics.

Advances in Nanotheranostics I

Advances in Nanotheranostics I PDF Author: Zhifei Dai
Publisher: Springer
ISBN: 3662485443
Category : Technology & Engineering
Languages : en
Pages : 338

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Book Description
This book highlights the recent advances in nanotheranostics from basic research to potential applications, and discusses the modular design and engineering of multiplex nanoparticles including gold nanostructures, luminescent nanoparticles, dendrimers and liposomes. Each chapter demonstrates multifunctional nanoparticles with topics covering targeting, imaging, delivery, diagnostics, and therapy as new modalities for cancer theranostics. This comprehensive book presents expert views on the latest developments in theranostic nanomedicine. It focuses on potential theranostic applications of multifunctional nanoparticles ranging from identifying noninvasively cancer cells by molecular detection, and visualizing in vivo drug delivery by means of contrast enhanced imaging, to destroying cancer cell s with minimal side effects via selective accumulation at tumor sites, and real-time monitoring therapeutic effectiveness. It also presents an interdisciplinary survey of nanotheranostics and as such is a valuable resource for researchers and students in related fields. Zhifei Dai is a Professor at the Department of Biomedical Engineering, College of Engineering, Peking University, China.

Theranostic Imaging in Cancer Precision Medicine

Theranostic Imaging in Cancer Precision Medicine PDF Author: Marie-France Penet
Publisher: Frontiers Media SA
ISBN: 2889744728
Category : Medical
Languages : en
Pages : 115

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Book Description


Stabilized Nanobubbles for Diagnostic Applications

Stabilized Nanobubbles for Diagnostic Applications PDF Author: Christopher Hernandez
Publisher:
ISBN:
Category : Biomedical engineering
Languages : en
Pages : 181

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Book Description
.Bulk nanobubbles, also known as ultrafine bubbles (ISO/ TC281), have recently gained the interest of the research community for their potential application as ultrasound contrast agents for molecular imaging and cancer therapy. However, even with this growing interest, the very existence of nanobubbles and their use as contrast agents have been a subject of controversy for over a decade. This is due to the theoretical effect of reducing the bubble diameter to the nanoscale on both its Laplace pressure and resonance frequency leading to instability and reduced imaging quality, respectively. Despite these theoretical limitations, we have developed a stable and echogenic nanobubble formulation through incorporation of Pluronic, a nonionic triblock co-polymer surfactant, into the lipid shell of perfluorocarbon gas bubbles. To further understand the biophysical properties of these novel nanobubbles, we explored factors contributing to their echogenicity, stability, and fate after gas dissipation. Bubbles were confirmed to be in the sub-micron range and produced strong contrast at clinical ultrasound frequencies. Additionally, it was demonstrated that the incorporation of Pluronic into the lipid membrane increases the stability of nanobubbles under ultrasound by decreasing its monolayer surface tension. Due to the strong interest in the use of nanobubbles as drug delivery agents, their ultimate fate when destroyed by high-power ultrasound was investigated using cryo-EM. Lastly, as a proof of study, CA-125 and PSMA-targeted nanobubbles were developed for the detection of ovarian and prostate cancer, respectively. Results demonstrated that nanobubbles can be used to target and reach antigens expressed on cancer cells beyond the tumor vasculature. Characterization and optimization of nanobubble properties achieved the creation of novel, stabilized nanobubbles for numerous potential clinical applications.